Gut Microbiota Modulation of Host Physiology: The Search for Mechanism (C1)

Scientific Organizers: Fredrik Bäckhed, Ruth E. Ley and Yasmine Belkaid


March 1—6, 2015

Keystone Resort, Keystone, Colorado, USA


Sponsored by Boehringer Ingelheim Pharmaceuticals, Inc., Cell Research, Nestlé Institute of Health Sciences, Novartis Institutes for BioMedical Research and Theravance Biopharma


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Meeting Summary



Over the past decade, it has become evident that the gut microbiome is an important environmental factor that affects many physiologic processes, such as cell proliferation and differentiation, behavior, immune function and metabolism. Moreover, it may contribute to a wide variety of diseases, including cancer, inflammatory diseases, metabolic diseases and responses to pathogens. This meeting will emphasize mechanistic understandings of the relationship between microbiota and host physiology, rather than simply characterize microbiota in different disease states. Speakers will address not only bacteria in the gut, but also fungi and microbiome on the skin and in the lung. The goal of the meeting is to facilitate the understanding by which mechanisms of the microbiota modulate host physiologic processes and increase our understanding of how an altered microbiota contributes to health and disease in humans. In addition, the broad representation of speakers from diverse fields, such as microbiology, immunology, physiology and infectious disease, is likely to foster new collaborations.