Exosomes/Microvesicles: Novel Mechanisms of Cell-Cell Communication (E4)

Scientific Organizers: Richard A. Cerione and Xandra O. Breakefield


June 19—22, 2016

Keystone Resort, Keystone, Colorado, USA


Supported by the Directors' Fund


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** Meeting has ended **

Discounted Abstract Deadline: February 18, 2016

*All deadlines end at 11:59 PM US Mountain Standard Time

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(The Abstract Deadline: is March 17, 2016)

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Abstract Deadline: March 17, 2016

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is February 18, 2016)

Discounted Registration Deadline: April 19, 2016

*All deadlines end at 11:59 PM US Mountain Standard Time


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*Includes 50.00 USD of your abstract submission fee

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Meeting Summary



An emerging area of great excitement in the cell biology and pharmaceutical/biotech communities involves the release and subsequent uptake of membrane-enclosed packets of information, often referred to as extracellular vesicles. These non-traditional vesicles contain a potent array of cargo, including hundreds of proteins such as growth factors and receptors, metabolic enzymes, transcription factors and a large variety of RNA transcripts as well as DNA. Extracellular vesicles span a range of sizes from 50 nm to 1 micron and comprise a heterogenous set, including exosomes and microvesicles that appear to be generated through distinct mechanisms. Extracellular vesicles are thought to serve as a means of cell-to-cell communication and contribute to a number of disease states, including cancer and neurodegeneration, thus offering new targets for therapeutic intervention and novel possibilities for diagnostic biomarkers. However, a number of important questions need to be answered. What are the regulatory cues that determine content and release of these vesicles from ”donor” cells? How many different types of extracellular vesicles are there and do they vary among cell types? Are there specific uptake mechanisms of vesicles into ”recipient cells” and is the cargo functional in these cells? The time is right for a Keystone Symposia meeting that covers this exciting area and aims to bring together investigators from different disciplines and areas of interest to present their newest findings concerning the biogenesis of extracellular vesicles, how they are shed and dock onto target cells, and the biological and disease consequences of their functions.