Capital Hotel Floorplan

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This meeting took place in 2009



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Human Immunology and Immunodeficiencies (D7)


Organizer(s) Lennart Hammarström, Xiao-Jun Xu, Jean-Laurent Casanova and Xiao-Ming Gao
May 12—17, 2009
Capital Hotel • Beijing, China
Abstract Deadline: Jan 12, 2009
Late Abstract Deadline: Feb 11, 2009
Scholarship Deadline: Jan 12, 2009
Early Registration Deadline: Apr 2, 2009

Organized in Collaboration with the Chinese Society of Immunology. Sponsored by Pfizer Inc.

Summary of Meeting:
The study of human immunodeficiency, whether inherited or acquired, is an outstanding and illuminating approach for the understanding of human immunology. The clinical investigation of these experiments of nature provide novel insights into the physiology of immune responses. In the course of this Keystone Symposia meeting we aim to bring together experts in the three related fields of primary immunodeficiencies, complex genetics of infectious diseases, and virus-induced immunodeficiency. The immunological and clinical lessons learned from the care and investigation of patients with these conditions will be discussed.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, MAY 12

15:00—19:30
Registration

Jinyun Foyer
18:30—19:30
Refreshments

Jinyun Foyer
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Lennart Hammarström, Karolinska Institute, Sweden

* Xiao-Jun Xu, Peking University Health Science Center, China

* Jean-Laurent Casanova, Rockefeller University, USA

* Xiao-Ming Gao, Peking University Health Science Center, China

Xuetao Cao, Chinese Academy of Medical Sciences, China
Immune Regulation by Antigen-Presenting Cells: From Basic to Clinic

20:30—21:30
Orientation for New Attendees and New Investigators
Keystone Symposia's Chief Scientific Officer, Dr. Andy Robertson, to lead discussion in a "What to Expect during your Attendance" for interested delegates.

Jinyun Ballroom

WEDNESDAY, MAY 13

07:30—08:30
Breakfast

Four Seasons Restaurant
07:30—08:30
Poster Setup

Jinyun Ballroom
08:30—11:30
Development of Immunity
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Lennart Hammarström, Karolinska Institute, Sweden

* Jean-Laurent Casanova, Rockefeller University, USA

Tasuku Honjo, Kyoto University Graduate School of Medicine, Japan
The Molecular Mechanism for Generation of Antibody Memory

Michael S. Neuberger, Medical Research Council, UK
The Functions of AID and other DNA Deaminases in Immunity

Max D. Cooper, Emory University, USA
Convergent Evolution of Adaptive Immunity

Yaofeng Zhao, China Agricultural University, China
Short Talk: Ornithorhynchus anatinus (platypus) Links the Evolution of Immunoglobulin Genes in Eutherian Mammals and Lower Tetrapods

10:10—10:30
Coffee Break

Jinyun Foyer
11:30—12:30
Lunch

Four Seasons Restaurant
12:15—15:00
Poster Session 1

Jinyun Ballroom
14:30—15:00
Coffee Available

Jinyun Foyer
15:00—17:00
Antibody Deficiencies
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Qiang Pan-Hammarström, Karolinska Institutet, Sweden

* Xi-Qiang Yang, Chongqing University of Medical Sciences, China

Mary Ellen Conley, Rockefeller University, USA
Defects in Early B Cell Development

Lennart Hammarström, Karolinska Institute, Sweden
Genetics of IgAD and CVID

Yu Lung Lau, University of Hong Kong, China
Primary Immunodeficiencies in Hong Kong

Stuart G. Tangye, Garvan Institute of Medical Research, Australia
Short Talk: B Cell Differentiation and Function in Patients with Defects in STAT3 Signaling

17:00
On Own for Dinner


THURSDAY, MAY 14

07:30—08:30
Breakfast

Four Seasons Restaurant
08:30—11:45
Non-B Cell PIDs
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Alain Fischer, CHU Necker, France

* Xiao-Jun Xu, Peking University Health Science Center, China

Luigi D. Notarangelo, Children's Hospital, Boston, USA
Human and Mice Models of Omenn Syndrome and Leaky SCID: Unraveling the Paradox of Autoreactivity, Immunopathology and Immune Deficiency

Yoshiyuki Minegishi, University of Tokushima, Japan
Molecular Basis of Hyper IgE Syndrome (HIES)

Jean-Pierre de Villartay, INSERM U768, France
DNA Repair in the Immune System: From V(D)J to IG Class Switch Recombination

Amos Etzioni, Rambam Medical Center, Israel
Leukocyte Adhesion Defects

Bodo Grimbacher, Royal Free Hospital & University College Medical School, UK
The Involvement of Th17 Cells in Primary Immunodeficiencies

10:10—10:30
Coffee Break

Jinyun Foyer
11:45—13:00
Lunch

Four Seasons Restaurant
13:00—14:30
Workshop 1

Jinyun Ballroom
* Amos Etzioni, Rambam Medical Center, Israel

* Xiao-Dong Zhao, Chongqing Medical University, China

Saleh Zaid Al-Muhsen, King Saud University, and King Faisal Specialist Hospital, Saudi Arabia
Molecular and Clinical Profile of a Large Cohort with Chronic Granulomatous Disease from Saudi Arabia

Raffaele Badolato, Universita di Brescia, Italy
Abnormal Generation of NK-T Cell Subset in Hermansky-Pudlak Type 2 Syndrome Patients

Elissa K. Deenick, Garvan Institute of Medical Research, Australia
SAP Deficient Mice Reveal New Insights into the Mechanisms of T-B Collaboration

Liping Jiang, Children's Hospital of Chongqing Medical University, China
Deficiency of TH17 Cell Numbers in Two Hyper-IgE Syndrome Patients with STAT3 Gene Mutation

Pamela Lee, University of Hong Kong, Hong Kong
Genotype-Phenotype Correlation Study in 62 Patients with X-Linked Agammaglobulinemia

14:30—15:00
Coffee Available

Jinyun Foyer
15:00—16:30
Therapy for Primary Immunodeficiency Diseases
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Luigi D. Notarangelo, Children's Hospital, Boston, USA

* Xiao-Ming Gao, Peking University Health Science Center, China

Alain Fischer, CHU Necker, France
Severe Combined Immunodeficiences (SCID): Diversity, Pathophysiology and Gene Therapy

Matthew Porteus, Stanford University School of Medicine, USA
New Directions in Gene Therapy: Zinc Finger Nuclease Stimulated Homologous Recombination for the Treatement of Primary Immunodeficiencies

16:30
On Own for Dinner


FRIDAY, MAY 15

07:30—08:30
Breakfast

Four Seasons Restaurant
07:30—08:30
Poster Setup

Jinyun Ballroom
08:30—11:45
Genetics of Common Infectious Diseases
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Erwin Schurr, Research Institute of the McGill University Health Centre, Canada

Alexandre Alcaïs, University of Paris René Descartes-INSERM U550, France
Human Genetics of Mycobacterial Infections

Etienne Pays, Universite Libre de Bruxelles, Belgium
Genetics of Trypanosome Infection

Philip M. Murphy, NIAID, National Institutes of Health, USA
Complex Genetics of West Nile Virus Infection

Luis Quintana-Murci, Institut Pasteur, CNRS URA3012, France
Evolutionary Genetics as a Tool for Exploring New Frontiers of Host Defence

Jean-Laurent Casanova, Rockefeller University, USA
A Genetic Dissection of Immunity to Infection in Natura

10:10—10:30
Coffee Break

Jinyun Foyer
11:45—12:45
Lunch

Four Seasons Restaurant
12:15—15:00
Poster Session 2

Jinyun Ballroom
14:30—15:00
Coffee Available

Jinyun Foyer
15:00—17:00
Genetics of Common Infectious Diseases (continued)
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Philip M. Murphy, NIAID, National Institutes of Health, USA

* Etienne Pays, Universite Libre de Bruxelles, Belgium

Erwin Schurr, Research Institute of the McGill University Health Centre, Canada
Complex Genetics of Leprosy

Thomas B. Boren, Umea University, Sweden
Dynamics of Adhesin-Receptor interactions: Lessons from H. pylori

Shen-Ying Zhang, Rockefeller University, USA
Mendelian Genetic Predisposition to Herpes Simplex Encephalitis in Childhood

17:00—18:00
High Tea

Jinyun Foyer
18:00—19:30
Workshop 2

Jinyun Ballroom
* Yoshiyuki Minegishi, University of Tokushima, Japan

* Yu Lung Lau, University of Hong Kong, China

Kohsuke Imai, Tokyo Medical and Dental University, Japan
Primary Immunodeficiency Database Network in Japan

Xiao-Fei Kong, Rockefeller University, Casanova Laboratory, USA
A Novel form of Recessive STAT1 Deficiency Associated with Impaired but not Abolished Responses to IFN-alpha/beta, IFN-gamma, IFN-lambda1 and IL-27

Elin Alexandra Kindberg, University of Linköping, Sweden
A Deletion in the Chemokine Receptor 5 (CCR5) Gene is Associated with Tick-Borne Encephalitis

Marie Meeths, Karolinska Institutet, Sweden
Spectrum and Clinical Presentation of RAB27A Mutations

Vanessa Sancho Shimizu, University Paris Descartes Faculty of Medicine Necker, France
Novel Genes Controlling Susceptibility to Herpes Simplex Encephalitis


SATURDAY, MAY 16

07:30—08:30
Breakfast

Four Seasons Restaurant
08:30—11:30
Mechanism of Immunodeficiency in HIV
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Daniel E. Kaufmann, University of Montreal, Canada

* Margaret A. Liu, ProTherImmune and Karolinska Institutet, USA

Adriano Boasso, Imperial College London, UK
Type I IFN and IDO-Mediated Immune Dysregulation in HIV Infection

Frank Kirchhoff, University of Ulm, Germany
Downregulation of Expression of MHC Class I Molecules by HIV

Guido Silvestri, Emory University School of Medicine, USA
HIV-Associated Chronic Immune Activation

Mary Carrington, Frederick National Laboratory for Cancer Research, USA
Immunogenetic Effects on HIV-1 Infection

10:10—10:30
Coffee Break

Jinyun Foyer
11:30
On Own for Lunch

16:30—17:00
Coffee Available

Jinyun Foyer
17:00—18:45
Mechanism of Immunodeficiency in HIV (continued)
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Frank Kirchhoff, University of Ulm, Germany

* Michael S. Neuberger, Medical Research Council, UK

* Mary Carrington, Frederick National Laboratory for Cancer Research, USA

Daniel E. Kaufmann, University of Montreal, Canada
Immunoregulatory Pathways and HIV-Specific T Cell Dysfunction

Brent E. Palmer, University of Colorado Health Sciences Center, USA
Dysregulation of CD4+ T Cell Coregulatory Receptor Expression during Chronic HIV Infection

Zuopeng Wu, John Curtin School of Medical Research, Australia
Short Talk: Pre-mRNA Alternative Splicing is Essential in Regulating T Cell Immunity and Homeostasis

18:45—19:30
Concluding Remarks
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
Margaret A. Liu, ProTherImmune and Karolinska Institutet, USA
Common and Contrasting Mechanisms of Acquired and Inherited Immunodeficiencies

19:30—20:30
Social Hour

Jinyun Foyer
20:30—21:30
Entertainment

Jinyun Ballroom

SUNDAY, MAY 17

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Invitrogen Corporation Pfizer Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676