The Westin Miyako Kyoto Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2010



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Bioactive Lipids: Biochemistry and Diseases (D2)


Organizer(s) Shuh Narumiya, Takao Shimizu and Garret A. FitzGerald
June 6—11, 2010
The Westin Miyako Kyoto • Kyoto, Japan
Abstract Deadline: Feb 23, 2010
Late Abstract Deadline: Mar 9, 2010
Scholarship Deadline: Feb 23, 2010
Early Registration Deadline: Apr 6, 2010

Sponsored by Astellas Pharma Inc. and Takeda Pharmaceutical Company Limited. Also supported by the Japan Society for the Promotion of Science in cooperation with Kyoto University.

Summary of Meeting:
The world of lipid mediators is expanding. New and unexpected biological functions, biosynthetic pathways and receptors are being revealed for lipids as appreciation grows for their complex interactions with protein and the genome. New actions are still being added to classic mediators such as prostaglandins and leukotrienes. Lipid mediators are now recognized to influence a broad swath of biology from inflammation to allergy, immunity, cardiovascular diseases, cancer and behavior. Advances in lipidomics enable us to monitor dynamics of a variety of lipid mediators simultaneously. In this symposium we invite distinguished scientists to share their progress in this expanding field and to present a comprehensive view on what lipid mediators do in our body. We also invite scientists interested in the translation of such basic science from model systems to an understanding of the role of lipids in human physiology, disease and drug action. Expansion of our understanding of the role of lipid mediators affords the opportunity for novel therapeutic opportunities, examples of which will be discussed in the symposium.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, JUNE 6

15:00—19:30
Registration

Mizuho Foyer
18:30—19:30
Refreshments

Mizuho Foyer
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Shuh Narumiya, Kyoto University, Japan

Osamu Hayaishi, Osaka Bioscience Institute, Japan
Prostaglandins and Sleep


MONDAY, JUNE 7

07:30—08:30
Breakfast

Mizuho Ballroom
07:30—08:30
Poster Setup

Mizuho Ballroom
08:30—19:00
Poster Viewing

Mizuho Ballroom
08:30—12:00
Biochemistry of Lipid Metabolism I
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Edward A. Dennis, University of California, San Diego, USA

* Jesper Z. Haeggstrom, Karolinska Institute, Sweden

Takao Shimizu, University of Tokyo, Japan
Turnover of Glycerophospholipids by Deacylation-Reacylation Cycle

Makoto Murakami, Tokyo Metropolitan Institute of Medical Science, Japan
Biological Functions of sPLA2s

Sasanka Ramanadham, UAB Comprehensive Diabetes Center, USA
Involvement of Novel iPLA2beta-Dependent Mechanisms in beta-Cell Apoptosis

William L. Smith, University of Michigan, USA
Cyclooxygenase Homodimers Function as Conformational Heterodimers with Allosteric and Catalytic Subunits

Michael H. Gelb, University of Washington, USA
Short Talk: Phospholipase A2 Mediated Eicosanoid Generation During Inflammation

Claude Wolf, Faculté de Médecine St Antoine, France
Short Talk: Profiling of Liver Triglycerides Reveals Specific Molecular Species Associated with Fatty Liver in Mice

09:40—10:00
Coffee Break

Mizuho Foyer
12:00—13:00
Lunch

Mizuho Ballroom
12:30—15:00
Poster Session 1

Mizuho Ballroom
14:45—15:00
Coffee Available

Mizuho Foyer
15:00—17:30
Biochemistry of Lipid Metabolism II
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Takao Shimizu, University of Tokyo, Japan

* William L. Smith, University of Michigan, USA

Kikuko Watanabe, Koshien University, Japan
A Novel Type of PGF Synthase belonging to the Thioredoxin-Like Superfamily

Jesper Z. Haeggstrom, Karolinska Institute, Sweden
Structure and function of LTA4 hydrolase, LTC4 synthase, and related enzymes

B. Therese Kinsella, University College Dublin, Ireland
Biochemistry of the Human Prostacyclin Receptor

Edward A. Dennis, University of California, San Diego, USA
Short Talk: Lipidomics of Eicosanoids in Cell Signaling and Inflammation

Toshiko Suzuki-Yamamoto, Okayama Prefectural University, Japan
Short Talk: Localization of Prostaglandin F2alpha Synthase and Receptor FP in the Rat Cerebellum

Marcia E. Newcomer, Louisiana State University, USA
Short Talk: The Crystal Structure of Human 5-Lipoxygenase

17:30
On Own for Dinner


TUESDAY, JUNE 8

07:30—08:30
Breakfast

Mizuho Ballroom
08:30—12:00
Biochemistry of Lipid Metabolism III
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Jerold J. Chun, The Scripps Research Institute, USA

* Kikuko Watanabe, Koshien University, Japan

Robert C. Murphy, University of Colorado Denver, USA
Transcellular Biosynthesis of Leukotrienes in vivo

Alan R. Brash, Vanderbilt University Medical Center, USA
Lipoxygenases, Essential Fatty Acids, and the Epidermis

Helena Idborg, Karolinska Institute, Sweden
Short Talk: Evaluation of Urinary Prostaglandin E2 Metabolite as a Biomarker of Inflammation

Michal L. Schwartzman, New York Medical College, USA
Cytochrome P450-Derived EETs and HETEs in Vascular Biology

Junken Aoki, Tohoku University, Japan
Autotaxin and LPA Signaling in Cardiovascular Development

Yutaka Yatomi, Graduate School of Medicine, The University of Tokyo, Japan
Short Talk: Clinical Introduction of Plasma Lysophosphatidic Acid and Serum Autotaxin Assays

09:40—10:00
Coffee Break

Mizuho Foyer
12:00
On Own for Lunch and Recreation

12:00—13:00
Poster Setup

Mizuho Ballroom
13:00—21:30
Poster Viewing

Mizuho Ballroom
15:45—16:00
Coffee Available

Mizuho Foyer
16:00—18:30
Immunoregulation
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Andrew D. Luster, Massachusetts General Hospital, USA

* Sarah Spiegel, Virginia Commonwealth University, USA

Suzanne Ostrand-Rosenberg, University of Maryland, USA
Prostaglandin E2 Drives Immune Suppression in the Tumor Microenvironment

Shuh Narumiya, Kyoto University, Japan
Prostanoids and Immune Inflammation

Kenji Chiba, Mitsubishi Tanabe Pharma Corporation, Japan
Immunoregulation by the Sphingosine 1-Phosphate Receptor Modulator, FTY720

Andreas Zimmer, University of Bonn, Germany
Endocannabinoids and Immunoregulation

Doina Ganea, Temple University School of Medicine, USA
Short Talk: Dendritic Cells – A Crucial Target for the Anti-Inflammatory Effects of Docosahexaenoic Acid (DHA)

Marc Stephan Lamphier, Eisai Research Institute, USA
Short Talk: A Novel Antagonist of the Prostaglandin E2 Receptor EP4 Inhibits Th1 Differentiation and Th17 Expansion and is Orally Active in Arthritis Models

18:30—19:30
Social Hour with Lite Bites

Mizuho Ballroom
19:00—21:30
Poster Session 2

Mizuho Ballroom

WEDNESDAY, JUNE 9

07:30—08:30
Breakfast

Mizuho Ballroom
08:30—12:00
Allergy and Inflammation
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Shuh Narumiya, Kyoto University, Japan

* Colin D. Funk, Queen's University, Canada

K. Frank Austen, Harvard Medical School, USA
The Integrated Biology of the Cysteinyl Leukotrienes and their Receptors

Andrew D. Luster, Massachusetts General Hospital, USA
Lipid-Cytokine-Chemokine Cascades Control Leukocyte Trafficking in Disease

Jilly F. Evans, PharmAkea Therapeutics, USA
Development of FLAP Inhibitors

Sarah Spiegel, Virginia Commonwealth University, USA
Novel Intracellular Targets of Sphingosine-1-Phosphate

Yumiko Imai, Akita University School of Medicine, Japan
Short Talk: Hyper-Response of Innate Immune System Triggered by Oxidative Stress and Oxidized Phospholipids Controls the Severity of Acute Lung Injury

Susanna Louise Lundström, Karolinska Institutet, Sweden
Short Talk: Allergic Asthmatics Exhibit Altered Responses in Oxylipin Profile Compared to Healthy and Asthmatic Controls following Allergen Provocation

09:40—10:00
Coffee Break

Mizuho Foyer
12:00
On Own for Lunch and Recreation

12:00—13:00
Poster Setup

Mizuho Ballroom
13:00—21:30
Poster Viewing

Mizuho Ballroom
15:45—16:00
Coffee Available

Mizuho Foyer
16:00—17:50
Nervous System
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Garret A. FitzGerald, University of Pennsylvania, USA

* Yoshihiro Urade, Osaka Bioscience Institute, Japan

Jerold J. Chun, The Scripps Research Institute, USA
Lysophospholipid Signaling in Disease

Daniele Piomelli, University of California, Irvine, USA
Endocannabinoids and the Brain

Shuntaro Hara, Showa University, Japan
Short Talk: Involvement of Microsomal Prostaglandin E Synthase-1 (mPGES-1) in Alzheimer’s Disease

Fumiaki Kojima, Asahikawa Medical College, Japan
Short Talk: Prostaglandin E2 Exacerbates Ischemic Brain Injury via the EP4 Receptor Subtype in Mice Subjected to a Middle Cerebral Artery Occlusion

17:50—18:30
Cardiovascular Diseases I
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
Shaun R. Coughlin, University of California, San Francisco, USA
Sphingosine-1-Phosphate in the Plasma Compartment Regulates Basal and Stimulated Vascular Leak in Mouse

18:30—19:30
Social Hour with Lite Bites

Mizuho Ballroom
19:00—21:30
Poster Session 3

Mizuho Ballroom

THURSDAY, JUNE 10

07:30—08:30
Breakfast

Mizuho Ballroom
08:30—12:00
Cardiovascular Diseases II
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Shaun R. Coughlin, University of California, San Francisco, USA

* Michal L. Schwartzman, New York Medical College, USA

Garret A. FitzGerald, University of Pennsylvania, USA
Cardiovascular Biology of the Prostanoids

Colin D. Funk, Queen's University, Canada
Eicosanoids in Cardiovascular Disease

Paola Patrignani, G. D'Annunzio University, Italy
Role of Prostanoids in Endothelial Biology

Alison M. Strack, Merck & Co., USA
Niacin and DP1 Antagonists: Studies in Mouse Models of Atherosclerosis

Barry Rubin, Toronto General Hospital, Canada
Short Talk: Lack of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) in Bone Marrow Derived Leucocytes Impairs Left Ventricular Remodelling and Increases Mortality After Myocardial Infarction

Yoshinori Katsumata, Keio University, Japan
Short Talk: Prostaglandin D2 Transduces Signals into Cardiomyocytes Independently of Canonical PGD2 Receptor

09:40—10:00
Coffee Break

Mizuho Foyer
12:00
On Own for Lunch and Recreation

15:45—16:00
Coffee Available

Mizuho Foyer
16:00—18:30
Immunomodulation by Lipid Mediators and Related Drugs
Meeting has ended...abstracts no longer viewable online.

Mizuho Ballroom
* Jilly F. Evans, PharmAkea Therapeutics, USA

* Alison M. Strack, Merck & Co., USA

Yoshihiro Urade, Osaka Bioscience Institute, Japan
PGD2 in Neuroinflammation and Muscular Dystrophy

Takayuki Maruyama, Ono Pharmaceutical Co.Ltd., Japan
Possibilities of EP Agonists and Antagonists for Novel Therapies

David F. Woodward, Allergan, Inc., USA
Short Talk: Design of Antagonists for PGF2alpha-Ethanolamide and PGE2-Glyceryl Ester by Using a Single Oxabicycloheptane Scaffold

Masataka Majima, Kitasato University School of Medicine, Japan
Short Talk: Recruitment of Mast Cells to the Tumor Microenvironment via the High Affinity Leukotriene B4 Receptor Regulates Tumor Stromal Profiles and Tumor-Associated Angiogenesis

18:30—19:30
Social Hour with Lite Bites

Mizuho Ballroom
18:30—20:30
Entertainment

Mizuho Ballroom

FRIDAY, JUNE 11

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13AI088818-01




We gratefully acknowledge additional support for this conference from:

Astellas Pharma Inc. Avanti Polar Lipids, Inc.
Daiichi Sankyo Co., Ltd. Dainippon Sumitomo Pharma Co., Ltd.
Japan Society for the Promotion of Science Kyowa Hakko Kirin Co., Ltd.
Mitsubishi Tanabe Pharma Corporation
Nacalai Tesque, Inc.

Novartis Pharma KK Japan Ono Pharmaceutical Co. Ltd.
Takeda Pharmaceutical Company Limited The Uehara Memorial Foundation

Asubio Pharma Co., Ltd.

Journal of Lipid Research

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Merck Research Laboratories


Minase Research Institute, Ono Pharmaceutical Co. Ltd.


Ono Pharmaceutical Co.Ltd.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Pubget Inc.

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676