Swissotel The Stamford Floorplan

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This meeting took place in 2010



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Developmental Origins and Epigenesis in Human Health and Disease (D1)


Organizer(s) Judith Swain, Peter D. Gluckman, Michael Meaney and Anne Ferguson-Smith
April 26—30, 2010
Swissotel The Stamford • Singapore, Singapore
Abstract Deadline: Dec 28, 2009
Late Abstract Deadline: Jan 29, 2010
Scholarship Deadline: Dec 28, 2009
Early Registration Deadline: Mar 12, 2010

In collaboration with Agency for Science, Technology and Research (A*STAR)

Summary of Meeting:
Developmental plasticity results from the interplay of fetal environment and genetic factors. There is considerable data to indicate that these interactions play an important role in the susceptibility of the individual to the development of chronic diseases such as diabetes, obesity, and to the cognitive capacity of that individual. Evidence suggests that gene/environment interactions may result in epigenetic changes that not only indicate susceptibility to chronic disease, but may play a causative role in the processes. The specific nature of the signaling pathways that dictate these susceptibilities and capacities are not known. This symposium is designed to explore experimental models of development, to understanding the role of epigenetics in regulating important signaling pathways, and to examine the relationship of the fetal environment to normal development and the susceptibility to chronic disease.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


MONDAY, APRIL 26

15:00—19:30
Registration

Stamford Foyer
18:30—19:30
Refreshments

Stamford Foyer
19:30—19:45
Opening Address and Welcoming Remarks

Stamford Ballroom
* Judith L. Swain, Singapore Institute for Clinical Sciences, Singapore

Chuan Poh Lim, Chairman, Agency for Science Technology and Research (A*STAR), Singapore

19:45—20:45
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Stamford Ballroom
* Anne C. Ferguson-Smith, University of Cambridge, UK

Adrian P. Bird, University of Edinburgh, UK
Investigating the Molecular Basis of Rett Syndrome


TUESDAY, APRIL 27

08:00—09:00
Breakfast

Stamford Ballroom
08:00—09:00
Poster Setup

Stamford Foyer
09:00—12:00
Mechanisms of Developmental Plasticity
Meeting has ended...abstracts no longer viewable online.

Stamford Ballroom
* Anne C. Ferguson-Smith, University of Cambridge, UK
Genomic Imprinting as an Adaptive Model of Developmental Plasticity

Stephen M. Cohen, Institute of Molecular and Cell Biology, Singapore
MicroRNA Functions: Insights from Drosophila Genetics

Emma Whitelaw, Queensland Institute of Medical Research, Australia
A New Model of Fetal Alcohol Spectrum Disordering in the Mouse

John S. Mattick, Garvan Institute of Medical Research, Australia
RNA as the Regulator of Epigenetic Memory and the Mediator of Epigenome-Environment Interactions

Kian Peng Koh, KU Leuven, Belgium
Short Talk: Tet1/Cxxc6 and Related Enzymes, a New Family of 5-Methylcytosine Hydroxylases, Modulate Pluripotency and Cell Lineage Specification in Mouse Embryonic Stem Cells

10:20—10:40
Coffee Break

Stamford Foyer
12:00—13:00
Lunch

Stamford Ballroom
12:00—17:00
Poster Viewing

Stamford Foyer
12:00—14:30
Poster Session 1

Stamford Foyer
14:30—15:00
Coffee Available

Stamford Foyer
15:00—17:00
Phenotypic Plasticity in Evolution
Meeting has ended...abstracts no longer viewable online.

Stamford Ballroom
* Russell D. Fernald, Stanford University, USA
Social Control of the Brain

Hamish G. Spencer, University of Otago, New Zealand
The Evolution of Phenotypic Plasticity: Insights from Theory

Diane Patricia Genereux, University of Washington, USA
Short Talk: Parent-Daughter Strand DNA Methylation Patterns: Snapshots of Epigenetic Processors

Yijun Ruan, University of Connecticut, USA
Short Talk: Estrogen Induced Chromatin Interaction and Transcription Regulation in Cancer Cells


WEDNESDAY, APRIL 28

08:00—09:00
Breakfast

Stamford Ballroom
08:00—09:00
Poster Setup

Stamford Foyer
09:00—12:00
Developmental Influences in Chronic Disease
Meeting has ended...abstracts no longer viewable online.

Stamford Ballroom
* Peter Gluckman, University of Auckland, New Zealand
The Developmental Contribution to the Risk of Chronic Disease

Caleb E. Finch, University of Southern California, USA
Early Exposure to Infections Accelerates Aging

Joseph H. Nadeau, Pacific Northwest Research Institute, USA
Transgenerational Epigenetic Control of Phenotypic Variation and Disease Risk

10:20—10:40
Coffee Break

Stamford Foyer
12:00—13:00
Lunch

Stamford Ballroom
12:00—17:00
Poster Viewing

Stamford Foyer
12:30—14:30
Poster Session 2

Stamford Foyer
14:30—15:00
Coffee Available

Stamford Foyer
15:00—17:00
Neural and Developmental Epigenetics
Meeting has ended...abstracts no longer viewable online.

Stamford Ballroom
* Michael Meaney, McGill University, Canada
Developmental Influences on Cognitive Processes

Yi Eve Sun, University of California, Los Angeles, USA
DNA Methylation and Neural Cell Fate

Zhao Xu, Beth Israel Deaconess Medical Center, USA
Pathway Discovery in Adipocyte Biology Using Epigenomics


THURSDAY, APRIL 29

08:00—09:00
Breakfast

Stamford Ballroom
09:00—11:40
Environmental Control of Tissue Differentiation
Meeting has ended...abstracts no longer viewable online.

Stamford Ballroom
Zofia Zukowska, University of Minnesota, USA
Gender-Specific Stress-Induced Programming for Obesity: Role of Neuropeptide Y and Adipose Stem Cells

Davor Solter, Institute of Medical Biology, Singapore

Judy C. Sng, Singapore Institute of Clinical Sciences, Singapore
Control of the Critical Period in Sensory Development

* Jonathan R. Seckl, University of Edinburgh School of Clinical Sciences & Community Health, UK
Glucocorticoid 'Programming' of the Brain: From Stress to Liquorice

10:20—10:40
Coffee Break

Stamford Foyer
14:45—15:00
Coffee Available

Stamford Foyer
15:00—17:00
Environmental Factors and Developmental Plasticity
Meeting has ended...abstracts no longer viewable online.

Stamford Ballroom
* Judith L. Swain, Singapore Institute for Clinical Sciences, Singapore

Michael K. Skinner, Washington State University, USA
The Environment and Epigenetics on Transgenerational Inheritance

Robert A. Waterland, Baylor College of Medicine, USA
The Search for Human Metastable Epialleles

Corrado Spadafora, Italian National Institute of Health, Italy
Retrotransposons, Reverse Transcriptase and the Genesis of New Genetic Information

17:00—19:00
Social Hour with Lite Bites

Stamford Foyer

FRIDAY, APRIL 30

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HD065349-01




We gratefully acknowledge additional support for this conference from:

Agency for Science, Technology and Research (A*STAR) Singapore Tourism Board

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


American Society for Human Genetics

Pubget Inc.

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


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If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

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Phone:+1 970-262-2676