Hilton Santa Fe Historic Plaza Hotel Floorplan

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This meeting took place in 2011



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Lung Development and Repair (B5)


Organizer(s) Brigid L.M. Hogan, Ross Metzger and Edward E. Morrisey
February 6—11, 2011
Hilton Santa Fe Historic Plaza Hotel • Santa Fe, New Mexico USA
Abstract Deadline: Oct 6, 2010
Late Abstract Deadline: Nov 8, 2010
Scholarship Deadline: Oct 6, 2010
Early Registration Deadline: Dec 3, 2010

Sponsored by Celgene Corporation

Summary of Meeting:
The lung is a complex three-dimensional organ. Its vital functions depend upon the initial establishment and maintenance of dynamic interactions between multiple tissue types. These include the highly branched system of airway tubes and terminal alveolar sacs, blood and lymphatic vessels, nerves, smooth muscle and fibroblasts, and cells of the immune system. Defects in these interactions underlie many serious respiratory disorders, both in the neonate and adult. This meeting will highlight recent advances in our understanding of the molecular and cellular processes driving the development of the lung and how its organization is maintained over the long term in the adult, as well as how these mechanisms are perturbed in disease. New ideas and approaches will be catalyzed by examples from other organ systems. The meeting will also address a major goal in lung biology - to identify the progenitor cells that mediate tissue regeneration and repair after damage by environmental factors or disease.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, FEBRUARY 6

15:00—20:00
Registration

Promenade
17:00
SuperBowl shown on the big screen.

Mesa A-B
18:15—19:15
Refreshments

Promenade
19:15—20:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Brigid L. M. Hogan, Duke University Medical Center, USA

Mark A. Krasnow, Stanford University School of Medicine, USA
Clonal Analysis of Lung Development, Maintenance and Cancer


MONDAY, FEBRUARY 7

07:00—08:00
Breakfast

Chamisa/Ortiz
08:00—11:00
How It All Begins
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
Kenneth S. Zaret, University of Pennsylvania, USA
Signaling to Chromatin during Induction of Foregut Organs

Ross J. Metzger, University of California, San Francisco, USA
Genetic Control of Airway Morphogenesis

Edward E. Morrisey, University of Pennsylvania, USA
Epigentic Regulation of Lung Development and Regeneration

Jörg Heierhorst, St. Vincent's Institute of Medical Research, Australia
Short Talk: The Zn2+-Finger Protein ASCIZ is an Essential Transcriptional Regulator of Pulmonary Organogenesis

* Lee A. Niswander, University of Colorado Boulder, USA
Lung Branching Morphogenesis Visualized and Coupled with Functional Genomics

09:20—09:40
Coffee Break

Promenade
11:00—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
11:00
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Promenade
17:00—19:00
Tissue Interactions in Lung and Organ Development
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Ross J. Metzger, University of California, San Francisco, USA

Frank Costantini, Columbia University, USA
Control of Branching Morphogenesis during Kidney Development

Nikolce Gjorevski, Princeton University, USA
Branching Programs in Engineered Tissues

Gail R. Martin, University of California, San Francisco, USA
A Surprising Role for FGF/Erk1/2 Signaling in Regulating Meiotic Spindle Orientation

David M. Ornitz, Washington University School of Medicine, USA
Short Talk: Growth Factor Signaling Pathways in Lung Mesenchyme Development

19:00—20:00
Social Hour with Lite Bites

Chamisa/Ortiz
19:30—22:00
Poster Session 1

Mesa C

TUESDAY, FEBRUARY 8

07:00—08:00
Breakfast

Chamisa/Ortiz
08:00—11:00
Progenitor Cells in Lung Development I
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Gail R. Martin, University of California, San Francisco, USA

Xin Sun, University of California, San Diego, USA
Elucidating the Genetic Network that Controls the Initiation of the Mammalian Respiratory Lineage

Maya Kumar, Stanford University, USA
Clonal Analysis of Mesenchymal Progenitors in Mouse Lung Development

John M. Shannon, Cincinnati Children's Hospital Medical Center, USA
Short Talk: Specification of Foregut Endodermal Cells to a Lung Fate Occurs Early in Development

Raphael Kopan, University of Cincinnati College of Medicine, USA
Notch Signaling and Lung Progenitors

Christos Samakovlis, Wenner-Gren Institute Stockholm University, Sweden
A Genome-Wide Analysis of Airway Maturation in Drosophila

09:20—09:40
Coffee Break

Promenade
11:00—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
11:00
On Own for Lunch and Recreation

14:30—16:30
Workshop

Mesa A-B
* Kenneth S. Zaret, University of Pennsylvania, USA

* Jeffrey A. Whitsett, Cincinnati Children's Hospital Medical Center, USA

Mélanie Bilodeau, Hospital for Sick Children, Canada
Tracking Lung Development

Amy P. Wong, Hospital for Sick Children, Canada
Establishment of CFTR-Expressing Epithelia from Pluripotent Stem Cells

Michael D. Green, Mount Sinai School of Medicine, USA
Generation of Anterior Foregut Endoderm From Human Embryonic and Induced Pluripotent Stem Cells

Ulrich Martin, Hannover Medical School, Germany
Differentiation of Murine Embryonic (mESCs) and Induced Pluripotent Stem Cells (miPSCs) into Definitive Endoderm and Airway Epithelial Cells

Olga G. Chernaya, University of Illinois, Chicago, USA
Isolation and Characterization of Candidate Mouse Lung Epithelial Progenitor Cells

16:30—17:00
Coffee Available

Promenade
17:00—19:00
Building Alveoli and the Lung Blood Supply
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Mark A. Krasnow, Stanford University School of Medicine, USA

M. Celeste Simon, University of Pennsylvania, USA
HIF-2alpha Deletion Promotes Kras-Driven Lung Tumor Development

Holger Gerhardt, Max Delbrück Center for Molecular Medicine, Germany
Mechanisms in Vascular Patterning

William T. Pu, Children's Hospital, Harvard Medical School, USA
More than a Cover: Mesothelium Function in Organ Development and Disease

Ashley N. Hipps, Vanderbilt University Medical Center, USA
Short Talk: NF-kappaB Activation in Fetal Lung Macrophages Disrupts Saccular Airway Formation

19:00—20:00
Social Hour with Lite Bites

Chamisa/Ortiz
19:30—22:00
Poster Session 2

Mesa C

WEDNESDAY, FEBRUARY 9

07:00—08:00
Breakfast

Chamisa/Ortiz
08:00—11:00
Establishing and Differentiating Epithelial Lineages
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Brigid L. M. Hogan, Duke University Medical Center, USA

John Wallingford, University of Texas at Austin, USA
Planar Cell Polarity in Development and Function of Mucociliary Epithelia

Wellington V. Cardoso, Columbia University Medical Center, USA
Notch Regulation of Airway Progenitors Cell Fate in Development and Regeneration

Jeffrey A. Whitsett, Cincinnati Children's Hospital Medical Center, USA
Ttf-1, Spdef and FoxA2 Interact in a Network Regulating Mucus Metaplasia and Innate Immunity

Liming Pei, Children's Hospital of Philadelphia/University of Pennsylvania, USA
Short Talk: TR Repression Prevents Type I Pneumocyte Associated Respiratory Distress Syndrome

Timothy J. Cole, Monash University, Australia
Short Talk: Glucocorticoid and Retinoic Acid Signaling during Late Gestation in the Mouse Lung

09:20—09:40
Coffee Break

Promenade
11:15—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
11:15
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Promenade
17:00—19:00
Progenitor Cells in Lung Development II
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Edward E. Morrisey, University of Pennsylvania, USA

Adam Giangreco, University College London, UK
Lung Stem Cells and Lineage Selection in Mammalian Conducting Airways

Barry R. Stripp, Duke University, USA
Defining Epithelial Progenitor Cells for Lung Maintenance and Repair

Saverio Bellusci, University of Southern California, USA
Fibroblast Growth Factor 10 Signaling in Lung Mesenchymal Lineage Formation

Jonathan L. McQualter, University of Melbourne, Australia
Short Talk: Organisation of Epithelial Stem/Progenitor Cells in the Adult Mouse Lung

19:00—20:00
Social Hour with Lite Bites

Chamisa/Ortiz
19:30—22:00
Poster Session 3

Mesa C

THURSDAY, FEBRUARY 10

07:00—08:00
Breakfast

Chamisa/Ortiz
08:00—11:15
Lung Injury and Repair
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Xin Sun, University of California, San Diego, USA

Harold A. Chapman, University of California, San Francisco, USA
Integrin alpha6beta4 Identifies an Adult Distal Lung Epithelial Population with Progenitor Potential in vivo

Dean Sheppard, University of California, San Francisco, USA
Contributions of Integrins to Lung Inflammation, Injury and Repair

Carla F. Kim, Boston Children's Hospital, USA
Stem Cell Approaches to Understand Lung and Injury Repair and Lung Cancers

Brigid L. M. Hogan, Duke University Medical Center, USA
Epithelial Stem Cells in Lung Development, Maintenance and Repair

Marie-Liesse Asselin-Labat, Walter and Eliza Hall Institute, Australia
Short Talk: Paracrine Signals Regulating Stem Cell Function

Catriona Y. Logan, Stanford University, USA
Short Talk: A Cis-Enhancer Region that Functions to Sense Lung Injury and Regulates Wnt Expression

09:20—09:40
Coffee Break

Promenade
11:15
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Promenade
17:00—19:00
Potential Cellular Therapies: Problems and Prospects?
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Harold A. Chapman, University of California, San Francisco, USA

Michael J. Welsh, University of Iowa, USA
Airway Abnormalities in Pigs with Targeted Disruption of the Gene Encoding CFTR

Jayaraj Rajagopal, Massachusetts General Hospital, USA
Airways from Endogenous Stem Cells

Darrell N. Kotton, Boston University, USA
Directed Differentiation of Pluripotent Stem Cells into Endodermal Lung Progenitors

20:00—21:00
Social Hour with Lite Bites

Promenade/Mesa Ballroom
20:00—23:00
Entertainment

Mesa Ballroom

FRIDAY, FEBRUARY 11

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HL106827-01




We gratefully acknowledge additional support for this conference from:

Celgene Corporation Cell Signaling Technology, Inc.
March of Dimes Foundation
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


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Phone:+1 970-262-2690

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