Boston Park Plaza Floorplan

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This meeting took place in 2011


Here are the related meetings in 2018:
Precision Medicine in Cancer (E1)
One Million Genomes: From Discovery to Health (G1)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Changing Landscape of the Cancer Genome (F3)


Organizer(s) Lynda Chin, Christoph Lengauer and Michael Stratton
June 20—25, 2011
Boston Park Plaza • Boston, Massachusetts USA
Abstract Deadline: Mar 7, 2011
Late Abstract Deadline: Mar 21, 2011
Scholarship Deadline: Feb 21, 2011
Early Registration Deadline: Apr 20, 2011

Sponsored by Bayer USA Foundation, Novartis Institutes for BioMedical Research, Onyx Pharmaceuticals, Inc., and Pfizer Inc.

Summary of Meeting:
Large scale cancer-genomics across the globe are capturing increasingly detailed views of the cancer genomes. These data have the potential to transform every aspect of cancer research. The challenges now are to decipher what the genomic landscape is teaching us about the initiation, progression and clinical behavior of a tumor. The goals of this meeting are (1) to bring together the data producers and analysts to share their latest findings, both technical and biological, from large-scale cancer genomic projects and address the challenges in analyses of these complex cancer genomic data; (2) to highlight how these genomic data are enabling a system/network-view of the genome and how the patterns of mutations are teaching new insight into underlying etiologies; and (3) to explore how cancer genomics can impact on drug discovery and development.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


MONDAY, JUNE 20

15:00—19:30
Registration

Imperial Check Room
18:15—19:15
Refreshments

Plaza Ballroom
19:15—20:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
Thomas J. Hudson, AbbVie, USA
Large-Scale Cancer Genomics


TUESDAY, JUNE 21

07:30—08:30
Breakfast

Plaza Ballroom
07:30—08:30
Poster Setup

Plaza Ballroom
08:30—17:00
Poster Viewing

Plaza Ballroom
08:30—12:00
Integrative Cancer Genome Projects
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
* Lynda Chin, University of Texas MD Anderson Cancer Center, USA
The Genomic Landscape of Glioblastoma

Nabahet Ameur, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Integrated Genomic Analysis and Next Generation Sequencing of Rhabdomyosarcoma Reveals Novel Molecular Alterations

James R. Downing, St. Jude Children's Research Hospital, USA
Molecular Pathology of Acute Leukemia

Andy Futreal, University of Texas MD Anderson Cancer Center, USA
The Somatic Genetic Architecture of Clear Cell Renal Carcinoma

Katherine A. Hoadley, University of North Carolina at Chapel Hill, USA
Short Talk: Progression in Triple Negative Breast Cancer: Comparing the Genomes of Primary and Multiple Metastatic Tumors

Matthew L. Meyerson, Dana-Farber Cancer Institute, USA
Somatic Genome Alterations in Human Epithelial Cancers

09:40—10:00
Coffee Break

Imperial Foyer
12:00—13:00
Lunch

Plaza Ballroom
12:30—15:00
Poster Session 1

Plaza Ballroom
15:00—16:30
NCI Health Disparities Workshop
The major goals of this workshop are to 1) know current basic research conducted in the biological factors associated with cancer health disparities; 2) to increase our overall understanding of the possible biological mechanisms with focus on molecular or cellular factors that may play a role in cancer health disparities; 3) educate the scientific community on basic research in cancer health disparities; and 4) build a network and community for basic research in cancer health disparities. The questions to be addressed in the workshop: - Are there biological differences between racial/ethnic population groups? - Does the biological difference identified lead to cancer health disparity? - Are there any research evidences to support biological differences that lead to cancer health disparities? - Can we develop interventions tailored to sub-populations (aimed at reducing disparity)?

Imperial Ballroom
* Ming Zhao, National Cancer Institute, National Institutes of Health, USA
Introduction: Basic Research in Cancer Health Disparities

Scott A. Waldman, Thomas Jefferson University, USA
Occult Tumor Burden Contributes to Racial Disparities in Stage-Specific Colorectal Cancer Outcomes

Effie W. Petersdorf, University of Washington, Fred Hutchinson Cancer Research Center, Seattle Cancer Care Alliance, USA
Genetic Mechanisms of Survivorship Disparities after Unrelated Hematopoietic Cell Transplantation

16:30—17:00
Coffee Available

Imperial Foyer
17:00—19:00
Genome Technologies: Current State and 3rd Generation
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
* Michael Stratton, Wellcome Trust Sanger Institute, UK

Stacey Gabriel, Broad Institute, USA
Overview of State of NGS and Where We Are Going with Next NGS

John D. McPherson, Ontario Institute for Cancer Research, Canada
Targeted Resequencing using the PacBio RS Platform

Wendy Winckler, Broad Institute of MIT and Harvard, USA
Short Talk: Transcript Profiling Low Quantity/Low Quality Samples Using Illumina RNA Sequencing

Meredith Yeager, SAIC-National Cancer Institute, NIH, USA
Ion Torrent’s PGM Coupled with Fluidigm’s Access Array Provides a Multiplexed Sample Approach to Rapid Evaluation of Novel Genomic Targets

19:00
On Own for Dinner


WEDNESDAY, JUNE 22

07:30—08:30
Breakfast

Plaza Ballroom
07:30—08:30
Poster Setup

Plaza Ballroom
08:30—17:00
Poster Viewing

Plaza Ballroom
08:30—12:00
Cancer Genome Analysis: Bioinformatics
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
* Iya G. Khalil, GNS Healthcare, USA

Peter Campbell, Wellcome Trust Sanger Institute, UK
Mutation and Indel Calling

Amy Brock, Harvard University, USA
Short Talk: Network Inference Modeling Identifies Targets for Mammary Cancer Reversal

Josh Stuart, University of California, Santa Cruz, USA
Inferring Pathway Activities from Integrated Cancer Genomics Data

Marco A. Marra, British Columbia Cancer Agency, Canada
Do Mutations in Histone Modifying Genes Drive B Cell Lymphomas?

Silvio Bicciato, University of Modena and Reggio Emilia, Italy
Short Talk: Inferring Cancer Metastasis Pathways from Meta-Analysis of Genomics Data

Gaddy Getz, Broad Institute, USA
Structure of Genome at Break Points/Rearrangement

09:40—10:00
Coffee Break

Imperial Foyer
12:00—13:00
Lunch

Plaza Ballroom
12:30—15:00
Poster Session 2

Plaza Ballroom
15:00—16:30
Workshop 1: Analysis of Next Generation Sequencing Data for the Power Users

Imperial Ballroom
* Peter Campbell, Wellcome Trust Sanger Institute, UK

Kristian Cibulskis, Broad Institute, USA
muTect: A Reliable and Accurate Method for Detecting Somatic Mutations in Next Generation Cancer Genome Sequencing

Nathan D. Dees, Washington University, USA
MuSiC: Identifying Mutational Significance in Cancer Genomes

Matthew D. Wilkerson, University of North Carolina at Chapel Hill, USA
Sequence Mutations, Transcript Isoforms, and Concurrent Gene Alterations in Lung Cancer

Boris A. Reva, Memorial Sloan Kettering Cancer Center, USA
Predicting the Functional Impact of Protein Mutations: Application to Cancer Genomics

Francesco Ferrari, Harvard Medical School, USA
What is the Optimal Read Length for Next Generation Sequencing Experiments?

Xin Victoria Wang, Dana Farber Cancer Institute, USA
Estimation of Sequencing Error Rates in Short Reads

16:30—17:00
Coffee Available

Imperial Foyer
17:00—19:00
Cancer Genome Analysis: Algorithm Development and Network Modeling
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
* Gaddy Getz, Broad Institute, USA

James J. Collins, Broad Institute of MIT & Harvard, USA
Reversed Engineering Network Modeling of Cancer Genomic Data

Iya G. Khalil, GNS Healthcare, USA
Therapeutically-Driven Network Models of Cancer

Raymond J. Cho, University of California, San Francisco, USA
Short Talk: Temporal Dissection of Tumorigenesis in Primary Cancers

Andrea Califano, Columbia University, USA
Integrative and Systems Genomics Approaches for the Systematic Elucidation of Tumor Initiation and Progression

19:00
On Own for Dinner


THURSDAY, JUNE 23

07:30—08:30
Breakfast

Plaza Ballroom
08:30—12:00
Integrative Cancer Genome Projects
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
* Giulio F. Draetta, University of Texas MD Anderson Cancer Center, USA

Victor E. Velculescu, Johns Hopkins University, USA
Personalized Genomic Analyses of Human Cancer

Katerina A. Politi, Yale University School of Medicine, USA
Short Talk: Focused Gene Re-Sequencing of Murine Lung Adenocarcinomas to Identify Genes Involved in Metastatic Progression and Drug Resistance

Xose S. Puente, University of Oviedo, Spain
Chronic Lymphocytic Leukemia Genome Project

Jessica Zucman-Rossi, INSERM U674, France
Molecular Classification of Benign and Malignant Liver Tumors

David T.W. Jones, DKFZ, Germany
Short Talk: A Few Old Friends and Many New Faces – First Results from the ICGC Pediatric Brain Tumor Project

Richard K. Wilson, Washington University School of Medicine, USA
Recent Advances in Cancer Genome Sequencing

09:40—10:00
Coffee Break

Imperial Foyer
12:00—13:00
Poster Setup

Plaza Ballroom
13:00—22:00
Poster Viewing

Plaza Ballroom
11:30
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Imperial Foyer
17:00—19:00
Genome Biology
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
* Matthew L. Meyerson, Dana-Farber Cancer Institute, USA

Michael Stratton, Wellcome Trust Sanger Institute, UK
Genomic Characteristics of Breast Cancers

Franziska Michor, Dana-Farber Cancer Institute, USA
Evolution of the Cancer Genome

Moritz Gerstung, ETH Zurich, Switzerland
Short Talk: Revealing Intra-Tumor Heterogeneity with Ultra-Deep Sequencing

Levi A. Garraway, Eli Lilly and Company, USA
Characterizing the Prostate Cancer Genome

19:00—20:00
Social Hour with Lite Bites

Plaza Ballroom
19:30—22:00
Poster Session 3

Statler Room

FRIDAY, JUNE 24

07:30—08:30
Breakfast

Plaza Ballroom
08:30—12:00
Beyond the Genome
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
Peter W. Laird, Van Andel Research Institute, USA
Mining the Cancer Methylome

Ido Amit, Weizmann Institute, Israel
Short Talk: Principles of Dynamic Gene Regulation in Mammals

Marc Vidal, Dana-Farber Cancer Institute, USA
Interactome Network and Cancer Genome

* Arul M. Chinnaiyan, University of Michigan, USA
Recurrent Gene Fusions in Common Solid Tumors: Implications for Personalized Medicine

Ian G. Campbell, Peter MacCallum Cancer Centre, Australia
Short Talk: Identification of Familial Cancer Susceptibility Genes Using Whole Exome Sequencing

Todd R. Golub, Broad Institute, USA
Genomics of Cancer Progression and Metastasis

09:40—10:00
Coffee Break

Imperial Foyer
12:00
On Own for Lunch

14:30—16:30
Workshop 2: Accessing Cancer Genomics Data for the Biologists

Imperial Ballroom
* Murray O. Robinson, Molquant, Inc., USA

Nikolaus Schultz, Memorial Sloan-Kettering Cancer Center, USA
The cBio Cancer Genomics Portal

Arek Kasprzyk, Ontario Institute for Cancer Research, Canada
International Cancer Genome Consortium Data Portal: One-Stop Shop for Cancer Genomic, Transcriptomic, and Epigenomic Data

Michael Noble, Broad Institute, USA
The Broad Institute TCGA Analysis Pipeline

Daniel R. Rhodes, University of Michigan, USA
Focal Amplification of Existing Kinase Inhibitor Targets Identified from TCGA Data and Integrative Analysis

Jingchun Zhu, University of California, Santa Cruz, USA
The UCSC Cancer Genomics Browser

Simon A. Forbes, Wellcome Trust Sanger Institute, UK
COSMIC, the Catalogue of Somatic Mutations in Cancer

16:30—17:00
Coffee Available

Imperial Foyer
17:00—19:00
Cancer Genomics and Drug Discovery
Meeting has ended...abstracts no longer viewable online.

Imperial Ballroom
Christoph Lengauer, Blueprint Medicines, USA
What is Needed to Convert a Genomic Target to a Therapeutic Target?

Murray O. Robinson, Molquant, Inc., USA
Exploring Genomics of Model Systems to Identify Response Biomarkers

Doron Lipson, Foundation Medicine, Inc., USA
Short Talk: Applying NGS to Cancer Genomics for Clinical Decision Making

Giulio F. Draetta, University of Texas MD Anderson Cancer Center, USA
Bridging the Gap between Cancer Genomics and Drug Discovery

19:00—20:00
Social Hour with Lite Bites

Georgian Room
20:00—23:00
Entertainment

Georgian Room

SATURDAY, JUNE 25

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13CA159787-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge additional support for this conference from:

Bayer USA Foundation Integrated DNA Technologies
Novartis Institutes for BioMedical Research Onyx Pharmaceuticals, Inc.
Pfizer Inc.
 

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