Granlibakken Tahoe Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2012



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Membranes in Motion (A5)


Organizer(s) Harvey T. McMahon and Jodi Nunnari
January 22—27, 2012
Granlibakken Tahoe • Tahoe City, California USA
Abstract Deadline: Sep 21, 2011
Late Abstract Deadline: Oct 24, 2011
Scholarship Deadline: Sep 21, 2011
Early Registration Deadline: Nov 21, 2011

Supported by the Directors’ Fund

Summary of Meeting:
Membranes allow for the compartmentalization of many different processes in the cell, thus allowing for organizational complexity. Membranes are now known to be direct players in cell physiology, including organelle structure and biogenesis, membrane transport and intracellular trafficking, as well as in dysfunctions leading to disease such as Huntington’s disease, chronic inflammation, viral infections and metastatic cell invasion. This symposium will cover emerging topics in membrane trafficking and disease. It will highlight progress in membrane fusion, fission and budding mechanisms as well as the recent expansion of endocytic pathways and their coupling to signaling. There will be an emphasis on the fundamental importance of controlling membrane curvature, beyond its role in shaping organelles looking forward to direct functions in organelle dynamics and organization. This symposium seeks to bring together those at the forefront of different disciplines to address current issues in membrane biology. The overlapping topics should stimulate discussion and cross-fertilization.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, JANUARY 22

15:00—19:30
Registration

Pre Function
18:15—19:15
Buffet Dinner

Granhall
19:15—20:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
Tom A. Rapoport, Harvard University Medical School, USA
How the Endoplasmic Reticulum Gets into Shape


MONDAY, JANUARY 23

07:00—08:00
Breakfast

Granhall
08:00—11:15
Disease States and Membrane Trafficking Mechanisms I
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
* Joshua Zimmerberg, NICHD, National Institutes of Health, USA

Ari Helenius, ETH Zurich, Switzerland
Viruses, Caveolae, and Endosomes: Confining Caveolae to the Plasma Membrane

Chiara Zurzolo, Institut Pasteur, France
Role of Tunneling Nanotubes (TNTs) in Prion Intercellular Spreading

Jocelyn Laporte, Institute of Genetics and Molecular and Cellular Biology, France
Short Talk: Dynamin 2 in Skeletal Muscle Development and Diseases

Ron R. Kopito, Stanford University, USA
Prion-Like Intercellular Transmission of Protein Aggregates in Neurodegenerative Disease

Pascale Cossart, Institut Pasteur, France
Pathogenic Bacteria and Membrane Trafficking

Daniel Humphreys, Cambridge University, UK
Short Talk: WAVE is Activated by Cooperating Arf and Rac1 GTPases, and Targeted by Pathogen and Host GEFs during Invasion

09:20—09:40
Coffee Break

Pre Function
11:15—13:00
Poster Setup

Bay
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Bay
16:30—17:00
Coffee Available

Pre Function
17:00—19:00
Disease States and Membrane Trafficking Mechanisms II
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
* Thomas Langer, CECAD Research Center, Germany

Thomas J. Jentsch, Max-Delbrück-Center for Molecular Medicine (MDC), Germany
The Need for H+-Driven Vesicular Cl- Accumulation: Insights from Human Disease, Mice and Biophysics

Ira Mellman, Genentech, Inc., USA
Cancer and Membrane Trafficking

Miguel A. del Pozo, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Spain
Short Talk: Caveolin-1 in Membrane Trafficking and Biomechanical Remodeling of the Tumor Microenvironment

Emmanuel Boucrot, MRC Laboratory of Molecular Biology, UK
Short Talk:

19:00—20:00
Dinner

Granhall
20:00—22:00
Poster Session 1

Bay
20:00—21:00
Social Hour

Bay

TUESDAY, JANUARY 24

07:00—08:00
Breakfast

Granhall
08:00—11:15
Clathrin-Dependent Endocytosis
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
* Satyajit Mayor, National Centre for Biological Sciences, India

Tom Kirchhausen, Harvard Medical School, USA
Dynamics of Endocytosis

Pietro V. De Camilli, Yale University School of Medicine, USA
BAR Proteins and Vesicle Budding

Vadim A. Frolov, University of the Basque Country, Spain
Short Talk: Catalytic Pathway of Membrane Remodeling by a Minimal Dynamin Complex

Oliver Daumke, Max-Delbrück-Center for Molecular Medicine (MDC), Germany
Structure, Function and Mechanism of Dynamin Superfamily Proteins

Joshua S. Chappie, NIDDK/National Institutes of Health, USA
Short Talk: A Pseudo-Atomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke

Hiroyuki Kamiguchi, RIKEN Brain Science Institute, Japan
Growth Cone Membrane Trafficking for Axon Guidance

09:20—09:40
Coffee Break

Pre Function
11:15—13:00
Poster Setup

Bay
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Bay
14:30—16:30
Workshop: Vesicle Biogenesis and Secretion

Mountain/Lake
* Ira Mellman, Genentech, Inc., USA

Cédric Asensio, University of California, San Franciso, USA
Adaptor Protein AP-3 and VPS41 are Required for the Biogenesis of the Regulated Secretory Pathway

Daniel Kümmel, Yale School of Medicine, USA
Structural Basis for Clamping of Membrane Fusion by Complexin

Roberto Weigert, NIDCR-National Institutes of Health, USA
Role for the Acto-Myosin Complex in Regulated Exocytosis Revealed by Intravital Microscopy

Christian Ungermann, University of Osnabrück, Germany
Molecular Architecture and Function of the HOPS Tethering Complex

Evzen Boura, NIDDK, National Institutes of Health, USA
Solution Structure and Mechanism of the ESCRT-I and –II Membrane Budding Assembly

Aaron T. Cheng, University of California, Berkeley, USA
Genome Editing in Embryonic Stem Cells for Live-Cell Analysis of Clathrin-Mediated Endocytosis



Junjie Hu, Nankai University, China
Structural Insight into Golgi Membrane Stacking by GRASP55 and GRASP65

16:30—17:00
Coffee Available

Pre Function
17:00—19:00
Clathrin-Independent Endocytosis
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
* Richard Lundmark, Umeå University, Sweden

Satyajit Mayor, National Centre for Biological Sciences, India
Regulated Organization of Cell Surface Molecules Templated by Dynamic Cortical Actin

Robert G. Parton, University of Queensland, Australia
New Insights into the Formation and Function of Caveolae

Julie G. Donaldson, NHLBI, National Institutes of Health, USA
Clathrin-Independent Endocytosis: Sorting of Cargo Proteins after Entry

Derek C. Prosser, Johns Hopkins University, USA
Short Talk: Existence of a Novel Clathrin-Independent Endocytic Pathway in Yeast that Depends on Rho1 and the Formin Bni1

19:00—20:00
Dinner

Granhall
20:00—22:00
Poster Session 2

Bay
20:00—21:00
Social Hour

Bay

WEDNESDAY, JANUARY 25

07:00—08:00
Breakfast

Granhall
08:00—11:15
Membrane Dynamics I: Cell Fusion Mechanisms
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
* Harvey T. McMahon, MRC Laboratory of Molecular Biology, UK

Benjamin Podbilewicz, Technion, Israel
The Role of EFF and AFF Proteins in Cell-Cell Fusion both in vivo and in vitro

Roy Duncan, Dalhousie University, Canada
The Reovirus FAST Proteins: Virus-Encoded Cellular Fusogens

Renjith Mathew, EMBL, Germany
Short Talk: Membrane Dynamics during Polarized Growth of Tracheal Terminal Cells in Drosophila

Masaru Okabe, Osaka University, Japan
The Dynamic Movement of IZUMO1 and CD9 during Fertilization Process in Mouse

Gavin J. Wright, Wellcome Trust Sanger Institute, UK
Jamb and Jamc are Essential for Vertebrate Myocyte Fusion

Pablo S. Aguilar, Institut Pasteur de Montevideo, Uruguay
Short Talk: Yeast Mating, Cell Fusion and Lysis

09:20—09:40
Coffee Break

Pre Function
11:15—13:00
Poster Setup

Bay
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Bay
16:30—17:00
Coffee Available

Pre Function
17:00—19:00
Membrane Curvature as a Biological Effector
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
* Christian Ungermann, University of Osnabrück, Germany

Darryl Y. Sasaki, Sandia National Laboratories, USA
Model Systems for Understanding Membrane Budding and Tubulation

Sascha Martens, University of Vienna, Austria
Molecular Mechanisms of Autophagosome Formation

Bruno Antonny, Institut de Pharmacologie Moleculaire et Cellulaire, France
Curvature Sensing and Golgi Trafficking

Ralf Langen, University of Southern California, USA
Short Talk: Relation between Protein Structure and Different Types of Membrane Curvature

19:00—20:00
Dinner

Granhall
20:00—22:00
Poster Session 3

Bay
20:00—21:00
Social Hour

Bay

THURSDAY, JANUARY 26

07:00—08:00
Breakfast

Granhall
08:00—11:30
Membrane Dynamics II: Organelle Fission and Fusion Mechanisms
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
* Junjie Hu, Nankai University, China

Jodi Nunnari, University of California, Davis, USA
Mitochondrial Dynamics

Ruth N. Collins, Cornell University, USA

Peter Novick, University of California, San Diego, USA
Short Talk: ER Network Structure Requires a Balance between the Dynamin-like GTPase Sey1p and a Novel Member of a Conserved Protein Family

Qing Zhong, University of California at Berkeley, USA
The Class III PI-3Kinase in Autophagosome Formation and Maturation

Thomas Wollert, Max Planck Institute of Biochemistry, Germany
Coatless: Membrane Budding and Scission by the ESCRT-Complexes

Holger Sondermann, Cornell University, USA
Short Talk: Structural Insights into the Molecular Mechanism of the G Protein Atlastin

Caroline Bruns, Center for Genomic Regulation, CRG, Spain
Short Talk: Biogenesis of a Novel Compartment for Autophagosome-Mediated Unconventional Protein Secretion

09:00—09:20
Coffee Break

Pre Function
 
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Pre Function
17:00—19:00
Membrane Quality Control Pathways
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake
* Jodi Nunnari, University of California, Davis, USA

Richard J. Youle, NINDS, National Institutes of Health, USA
Damage Control - How the Pink1/Parkin Pathway can Regulate Removal of Impaired Mitochondria by Autophagy

Suresh Subramani, University of California, San Diego, USA
Common Principles in Selective Autophagy from Studies on Pexophagy

Thomas Langer, CECAD Research Center, Germany
Prohibitins and Mitochondrial Membrane Dynamics

Brooke M. Gardner, University of California, San Francisco, USA
Short Talk: Unfolded Proteins are Ire1-Activating Ligands that Directly Induce the Unfolded Protein Response

Marijn Gerard Johannesburg Ford, UC Davis, USA
Short Talk:

19:00—20:00
Dinner

Granhall
20:00—23:00
Entertainment

Granhall

FRIDAY, JANUARY 27

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Avanti Polar Lipids, Inc. Landes Bioscience

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676