Fairmont Hotel Vancouver Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2012



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Gene Silencing by Small RNAs (B1)


Organizer(s) Richard W. Carthew and Olivier Voinnet
February 7—12, 2012
Fairmont Hotel Vancouver • Vancouver, British Columbia Canada
Abstract Deadline: Oct 6, 2011
Late Abstract Deadline: Nov 10, 2011
Scholarship Deadline: Oct 6, 2011
Early Registration Deadline: Dec 14, 2011

Supported by the Directors’ Fund

Summary of Meeting:
The impact of small non-coding RNAs has profoundly touched the fields of development and cell biology, functional genomics, human disease and drug therapy. This mode of gene regulation is not restricted to eukaryotes; bacteria utilize small RNAs, notably those made from CRISPR loci that silence the expression of bacteriophages, transposons and plasmids. There are still many gaps in our knowledge of the mechanisms used by small RNAs, particularly newly discovered RNAs. It has become clear that this field of study needs an annual forum to enable rapid dissemination of new discoveries between researchers. Overall, the goals of this proposed meeting are: (1) to foster the scientific development of junior investigators by promoting their interaction with established investigators, and (2) to allow for mixing and sharing of ideas between biochemists, molecular biologists, geneticists and systems biologists working in the field. We hope this will synergize ideas and method breakthroughs in small RNA mechanisms.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, FEBRUARY 7

15:00—19:30
Registration

British Columbia Foyer
18:15—19:15
Refreshments

British Columbia Foyer
19:15—20:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
Susan Gottesman, NCI, National Institutes of Health, USA
Unraveling Small RNA Function in E. coli


WEDNESDAY, FEBRUARY 8

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:15
Prokaryote and Eukaryote Models of RNA Silencing
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Olivier Voinnet, Swiss Federal Institute of Technology, Zürich, Switzerland

Jörg Vogel, University of Würzburg, Germany
RNA Ping-Pong in the GcvB Regulon

Erik Sontheimer, University of Massachusetts Medical School, USA
CRISPRs and their Role in Limiting Horizontal Gene Transfer

Daan C. Swarts, Wageningen University and Researchcentre, Netherlands
Short Talk: CRISPR-Mediated Plasmid Curing in Escherichia coli

Jennifer A. Doudna, HHMI/University of California, Berkeley, USA
Dicer/TRBP Interactions Influence Human Regulatory RNA Processing and Targeting

Annick Harel-Bellan, Commissariat à l'Energie Atomique (CEA), Saclay, France
Short Talk: Human Nuclear Argonaute Couples Chromatin-Mediated Silencing to Regulation of Alternative Splicing

Carl D. Novina, Dana-Farber Cancer Institute, USA
Short Talk: Reduced Expression of Ribosomal Proteins Relieves microRNA-Mediated Repression

Alejandro Vasquez-Rifo, University of Massachusetts Medical School, USA
Short Talk: A Vesicular Trafficking Complex Linked to the C. elegans microRNA Pathway

09:20—09:40
Coffee Break

British Columbia Foyer
11:15—13:00
Poster Setup

Pacific Ballroom
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Pacific Ballroom
16:30—17:00
Coffee Available

British Columbia Foyer
17:00—19:00
Non-Coding RNA Biogenesis in Eukaryotes
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Robert A. Martienssen, Cold Spring Harbor Laboratory, USA

V. Narry Kim, Seoul National University, South Korea
Regulation of MicroRNA

Jillian S. Shapiro, Mount Sinai School of Medicine, USA
Short Talk: In vivo Cytoplasmic Processing of Primary miRNAs

Mikiko C. Siomi, University of Tokyo, Japan
Biogenesis of piRNAs

Pablo A. Manavella, Max Planck Institute for Developmental Biology, Germany
Short Talk: Identification of New miRNA Biogenesis Cofactors by Fast-Forward Genetics

Yi Liu, University of Texas Southwestern Medical Center, USA
Short Talk: Reconstitution of an Argonaute-Dependent Small RNA Biogenesis Pathway Reveals the Roles of Exosome and the Exonuclease QIP in Small RNA Maturation

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
19:30—22:00
Poster Session 1

Pacific Ballroom

THURSDAY, FEBRUARY 9

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:15
Chromatin and Transcriptional Regulation
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Susan Gottesman, NCI, National Institutes of Health, USA

Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
S. pombe as a Model for Transcriptional Silencing

Jian-Kang Zhu, Purdue University, USA
Dynamic Regulation of DNA Methylation in Arabidopsis

Marc Bühler, Friedrich Miescher Institute for Biomedical Research, Switzerland
EMBO Young Investigator Short Talk: Identification of a Silencing Factor that Links Transcription within Heterochromatin to Downstream RNA Degradation

Scott G. Kennedy, University of Wisconsin, USA
Multi-Generational RNAi Inheritance and Germline Immortality

Eva-Maria Weick, Wellcome Trust/Cancer Research UK Gurdon Institute, UK
Short Talk: Transgenerational Epigenetic Inheritance in C. elegans: the Role of Small RNAs

Elissa P. Lei, NIDDK, National Institutes of Health, USA
Nuclear Functions for Drosophila AGO2 on Chromatin

09:20—09:40
Coffee Break

British Columbia Foyer
11:15—13:00
Poster Setup

Pacific Ballroom
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Pacific Ballroom
16:30—17:00
Coffee Available

British Columbia Foyer
17:00—19:00
Evolution of Small RNAs
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Phillip D. Zamore, University of Massachusetts Medical School, USA

David P. Bartel, HHMI, MIT and Whitehead Institute, USA
Systems Approaches to miRNAs

Emily Knouf, Fred Hutchinson Cancer Research Center, USA
Short Talk: Nucleotidyl Transferase Enzymes Regulate the Complexity and Expression of the microRNA Transcriptome

James C. Carrington, Donald Danforth Plant Science Center, USA
Evolutionary Biology of Small RNAs in Plants

Eric Meyer, Institut de Biologie de l'Ecole Normale Superieure, France
The scnRNA Pathway: A Highly Flexible Mechanism for Non-Mendelian Inheritance of Mating Types in the Ciliate Paramecium aurelia

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
19:30—22:00
Poster Session 2

Pacific Ballroom

FRIDAY, FEBRUARY 10

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:15
Mechanistic Nature of miRNAs
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Jennifer A. Doudna, HHMI/University of California, Berkeley, USA

Juan Guillermo Betancur, University of Tokyo, Japan
Short Talk: Dicer is Dispensable for Asymmetric RISC Loading in Mammals

Thomas F. Duchaine, McGill University, Canada
Mechanisms and Regulation of mRNA Deadenylation by RNAi Pathways

Qinghua Liu, University of Texas Southwestern Medical Center, USA
Short Talk: Autoantigen La Promotes Efficient RNAi, Antiviral Response, and Transposon Silencing by Facilitating Multiple-Turnover RISC Catalysis

Helge Großhans, Friedrich Miescher Institute - FMI, Switzerland
MicroRNA Turnover

Antonio J. Giraldez, Yale University School of Medicine, USA
Dynamic Analysis of mRNA Decay, Deadenylation and Ribosome Occupancy in vivo during miRNA Mediated Repression

Richard W. Carthew, Northwestern University, USA
Genetic Robustness and MicroRNAs

09:20—09:40
Coffee Break

British Columbia Foyer
11:15—13:00
Poster Setup

Pacific Ballroom
11:15
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Pacific Ballroom
16:30—17:00
Coffee Available

British Columbia Foyer
17:00—19:00
Small RNA Effector Proteins
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* James C. Carrington, Donald Danforth Plant Science Center, USA

Craig C. Mello, University of Massachusetts Medical School, USA
Argonautes in C. elegans

William Theurkauf, University of Massachusetts Medical Center, USA
Building a Transposon Silencing Compartment

Amit Anand, Temasek Life Sciences Laboratory, National University of Singapore, Singapore
Short Talk: A Tudor Domain Protein Qin/Kumo is Required for Transposon Repression and HP1 Post Translational Modification, with other piRNA Pathway Components

Phillip D. Zamore, University of Massachusetts Medical School, USA
Pachytene piRNA Production in Mouse Spermatogenesis

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
19:30—22:00
Poster Session 3

Pacific Ballroom

SATURDAY, FEBRUARY 11

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:15
More Surprises from RNA
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Mikiko C. Siomi, University of Tokyo, Japan

Andrew Fire, Stanford University, USA
A Few Things We Already Know (Or Do We?) about Small RNA Biogenesis and Function

Fedor V. Karginov, Cold Spring Harbor Laboratories, USA
Short Talk: Global Changes of Ago2-mRNA Interactions in Stress Response

Olivier Voinnet, Swiss Federal Institute of Technology, Zürich, Switzerland
“Caught in the Act” – The Awakening and Demise of a Plant Retrotransposon: When, Where, How?

David C. Baulcombe, University of Cambridge, UK
Evolution of RNA Silencing loci in Plants

Yijun Qi, Tsinghua University, China
Short Talk: A Role for Small RNAs in DNA Double-Strand Break Repair

Christina D. Smolke, Stanford University, USA
Design of Small RNAs for Synthetic Biology

09:00—09:20
Coffee Break

British Columbia Foyer
11:15
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

British Columbia Foyer
17:00—19:00
Small RNAs in Defense
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Richard W. Carthew, Northwestern University, USA

Raul Andino, University of California, San Francisco, USA
Antiviral Immunity in Drosophila: Systemic RNAi and Viral Suppressores

Ramesh S. Pillai, University of Geneva, Switzerland
piRNA Biogenesis and Functions of Piwi Protein Complexes

Alexei A. Aravin, California Institute of Technology, USA
piRNA Pathway in Flies and Mice

Séverine Chambeyron, Institute of Human Genetics, France
Short Talk: piRNA-Mediated Transgenerational Inheritance of an Acquired Trait

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
20:00—23:00
Entertainment

Pacific Ballroom

SUNDAY, FEBRUARY 12

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HD070616-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge additional support for this conference from:

Alnylam Pharmaceuticals, Inc. Found Animals' Michelson Prize & Grants in Reproductive Biology
Integrated DNA Technologies Sigma Life Science

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676