Snowbird Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2013



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Cardiac Remodeling, Signaling, Matrix and Heart Function (D4)


Organizer(s) Anthony J. Muslin, Jil C. Tardiff and Steven R. Houser
April 7—12, 2013
Snowbird Resort • Snowbird, Utah USA
Abstract Deadline: Dec 5, 2012
Late Abstract Deadline: Jan 9, 2013
Scholarship Deadline: Dec 5, 2012
Early Registration Deadline: Feb 6, 2013

Sponsored by Bayer USA Foundation, Novartis Institutes for BioMedical Research and Takeda Pharmaceutical Company Limited

Summary of Meeting:
The general topic of this meeting pertains to anatomic and physiologic changes that contribute to the development of heart failure and cardiac arrhythmias. More specifically, it will highlight recent scientific advances in cardiac biology and heart failure research and relate these insights to the development of novel clinical therapeutics that may impact patient care. This 4-day meeting will bring together both academic and industrial scientists employing state-of-the-art technologies encompassing the fields of stem cell science, tissue regeneration, bioengineering, non-coding RNAs, human and animal genetics, calcium signaling, autophagy and proteolysis, cardiac mechanics, and cardiac matrix biology. The translation of basic scientific discovery to pre-clinical drug development will be emphasized. In addition, there will be a workshop that details recent advances in development of novel therapeutic agents to treat heart failure and arrhythmias. This Keystone Symposia meeting is organized to provide scientists with diverse areas of expertise knowledge of technological applications and biological insights about the development and pathophysiology of cardiac dysfunction and arrhythmias. Interaction between scientists will be promoted through lectures, poster sessions, informal discussions and workshops in an environment that is highly conducive to cross-talk.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, APRIL 7

16:00—20:00
Arrival and Registration

Ballroom Lobby

MONDAY, APRIL 8

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Anthony J. Muslin, Sanofi, USA

Bruce M. Spiegelman, Harvard Medical School, USA
Capturing the Benefits of Exercise at the Molecular Level: Toward a New Generation of Therapeutics

09:00—12:00
Regenerating Injured Myocardium
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Anthony J. Muslin, Sanofi, USA

Deepak Srivastava, Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
Reprogramming Approaches for Cardiovascular Disease

Young-Jae Nam, University of Texas Southwestern Medical Center, USA
Molecular Strategies for Heart Repair and Regeneration

William T. Pu, Children's Hospital, Harvard Medical School, USA
Driving Heart Progenitor Cell Fate and Enhancing Cardiac Repair with Chemically Modified RNA

Issei Komuro, Tokyo University Graduate School, Japan
Cardiac Angiogenesis and Myogenesis

09:40—10:00
Coffee Break

Ballroom Lobby
12:00—13:00
Poster Setup

Superior/Superior Lobby
13:00—22:00
Poster Viewing

Superior/Superior Lobby
12:00—16:30
On Own for Lunch and Recreation

14:30—16:30
Workshop: Use of Human Induced Pluripotent Stem Cells to Model Cardiac Disease

Ballroom 2-3
* Jil C. Tardiff, University of Arizona, USA

Henning Kempf, Hannover Medical School, Germany
Improving Cardiomyogenic Differentiation of Human Pluripotent Stem Cells (hPSC) in Defined Conditions by the Application of Small Molecules

Rebecca Josowitz, Mount Sinai School of Medicine, USA
Modeling Cardiac Hypertrophy Using Patient Specific iPSC-Derived Cardiomyocytes

Marisa Ojala, University of Tampere, Finland
hiPSC Model for Hypertrophic Cardiomyopathy

J. Travis Hinson, Brigham and Women's Hospital, USA
Metabolic Regulation by AMPK in Cardiomyocytes Derived from an iPS Model of PRKAG2-Associated Cardiomyopathy

Ping Liang, Stanford University, USA
Drug Screening Using a Library of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes Reveals Disease Specific Patterns of Cardiotoxicity

Feng Lan, Stanford Medical School, USA
Abnormal Calcium Handling Properties Underlie Pathogenesis of Familial Hypertrophic Cardiomyopathy in Patient-Specific Induced Pluripotent Stem Cells

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
Bioengineering and Tissue Repair
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Jil C. Tardiff, University of Arizona, USA

Joseph C. Wu, Stanford University School of Medicine, USA
Imaging Cardiac Stem Cell Biology

Richard T. Lee, Harvard University, USA
Reversing Myocardial Aging

Josef M. Penninger, Institute of Molecular Biotechnology GmbH, Austria
ACE2 from Cardiovascular Control to Intestinal Inflammation and Malnutrition

19:00—20:00
Social Hour with Lite Bites

Superior/Superior Lobby
19:30—22:00
Poster Session 1

Superior/Superior Lobby

TUESDAY, APRIL 9

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—11:00
Genetic Causes of Cardiomyopathy
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Jil C. Tardiff, University of Arizona, USA

Elizabeth M. McNally, Northwestern University, USA
Common and Rare Genetic Variants as Modifiers for Myopathy

Christine E. Seidman, Harvard Medical School, USA
Modifying Phenotypic Expression in Hypertrophic Cardiomyopathy

Howard A. Rockman, Duke University Medical Center, USA
The Use of Drosophila Genetic Screens to Investigate Cardiomyopathy

Xuejun Wang, University of South Dakota, USA
Proteasome Dysfunction in Cardiac Pathogenesis

09:20—09:40
Coffee Break

Ballroom Lobby
11:00—13:00
Poster Setup

Superior/Superior Lobby
13:00—22:00
Poster Viewing

Superior/Superior Lobby
11:00—16:30
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
MicroRNA Regulation of Cardiac Function
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Steven R. Houser, Temple University School of Medicine, USA

Gerald W. Dorn, II, Washington University School of Medicine, USA
MicroRNA Regulation of Cardiac Hypertrophy and Failure

Edward E. Morrisey, University of Pennsylvania, USA
Promotion of Cardiomyocyte Proliferation by a miRNA-Hippo Mediated Pathway

Ronglih Liao, Brigham and Women's Hospital, USA
Unfolding the Misfolded Disease: Molecular Insights into AL Amyloid Cardiomyopathy

19:00—20:00
Social Hour with Lite Bites

Superior/Superior Lobby
19:30—22:00
Poster Session 2

Superior/Superior Lobby

WEDNESDAY, APRIL 10

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—11:00
Calcium Signaling, Protein Kinases and Cardiac Dysfunction
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Anthony J. Muslin, Sanofi, USA

Joan Heller Brown, University of California, San Diego, USA
CaMKIIdelta mediates myocardial ischemia/reperfusion injury through NFkB

Steven R. Houser, Temple University School of Medicine, USA
Microdomain-Based Ca2+ Influx Pathways that Regulate Pathological Hypertrophy and Contractility

Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
Proximal Disease Pathways Underlying Myofiber Necrosis in Muscular Dystrophy

Mark E. Anderson, Johns Hopkins University School of Medicine, USA
Calcium Signaling in Cardiac Arrhythmias

09:20—09:40
Coffee Break

Ballroom Lobby
11:00—13:00
Poster Setup

Superior/Superior Lobby
13:00—22:00
Poster Viewing

Superior/Superior Lobby
 
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
Cardiac Autophagy and Proteolysis
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Steven R. Houser, Temple University School of Medicine, USA

Norbert Perrimon, Harvard Medical School, USA
A Drosophila Model System to Study Glycogen Autophagy

Roberta A. Gottlieb, Cedars-Sinai Medical Center, USA
Mitophagy and Cardioprotection: The Heart’s “Cash for Clunkers” Program

Åsa B. Gustafsson, University of California, San Diego, USA
Mitochondrial Autophagy in Ischemic Myocardium

19:00—20:00
Social Hour with Lite Bites

Superior/Superior Lobby
19:30—22:00
Poster Session 3

Superior/Superior Lobby

THURSDAY, APRIL 11

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—11:00
Cardiac Mechanics
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Anthony J. Muslin, Sanofi, USA

Fady Malik, Cytokinetics Inc., USA
Cardiac Myosin Activation for the Treatment of Heart Failure

Jil C. Tardiff, University of Arizona, USA
Allosteric Mechanisms in Thin Filament Cardiomyopathies

Henk Granzier, University of Arizona, USA
The Role of Titin in Cardiac Function and Disease

Samantha Harris, University of California, Davis, USA
Functional Mapping of the M-Domain of Cardiac Myosin Binding Protein-C

09:20—09:40
Coffee Break

Ballroom Lobby
 
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
Cardiac Extracellular Matrix in Disease
Meeting has ended...abstracts no longer viewable online.

Ballroom 2-3
* Steven R. Houser, Temple University School of Medicine, USA

Walter J. Koch, Temple University School of Medicine, USA
A Dynamic and Critical Relationship between GRK2 and eNOS-NO in Myocardium

Thomas Eschenhagen, University Medical Center Hamburg-Eppendorf, Germany
Cardiac Tissue Engineering for Disease Modeling

Anthony J. Muslin, Sanofi, USA
Developing Drugs to Reduce Cardiac Fibrosis and Improve Function

19:00—20:00
Social Hour with Lite Bites

Ballroom 2-3
20:00—23:00
Entertainment

Ballroom 2-3

FRIDAY, APRIL 12

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Bayer USA Foundation Novartis Institutes for BioMedical Research
Takeda Pharmaceutical Company Limited
 

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HL118879-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge additional support for this conference from:

Cytokinetics, Inc. March of Dimes Foundation Grant No. 4-FY12-556

American Heart Association's Council on Basic Cardiovascular Sciences


InvivoSciences LLC

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Cytokinetics, Inc.


Novartis Institutes for BioMedical Research


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676