Registered Attendees
Registered Attendees
Print This PageRegistered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:
- Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting
(You can edit your own abstract from My Account page as well)
NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.
- Full participant list, including joint meeting participants
- Printable Invoices and Invitation Letters
- Scholarship Information
- Lodging Information
Login to My Account page
Close Window
Fairmont The Queen Elizabeth Floorplan
This meeting took place in 2013
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
Meeting Details
Autophagy, Inflammation and Immunity (B4)
Organizer(s) Herbert (Skip) W. Virgin, Beth Levine and Gökhan S. Hotamisligil
February 17 - February 22, 2013
Fairmont The Queen Elizabeth • Montreal, QC Canada
Abstract Deadline: October 16, 2012
Late Abstract Deadline: November 15, 2012
Scholarship Deadline: October 16, 2012
Early Registration Deadline: December 13, 2012
Sponsored by AbbVie Inc., Cell Research, EMD Millipore, Shire Human Genetic Therapies and Vertex Pharmaceuticals Incorporated
CME Information
Summary of Meeting:
Autophagy is a lysosomal degradation pathway by which eukaryotic cells break down their own components to adapt to nutrient deprivation. In multicellular organisms, autophagy and autophagy proteins also play a key role in the orchestration of diverse aspects of cellular and organismal responses to multiple dangerous stimuli, including infection. Thus, autophagy and autophagy proteins represent a key nexus within the cell through which multiple cellular and organismal stresses are integrated. This emerging understanding has led to exciting recent advances that, together, begin to paint a picture of how autophagy and autophagy proteins are involved in multiple diseases. Of particular interest, recent studies reveal a crucial role for autophagy pathways and proteins in immunity and inflammation. They balance the beneficial and detrimental effects of immunity and inflammation, and thereby may protect against infectious, autoimmune, and inflammatory diseases. The time is therefore ripe for a Keystone Symposia meeting that brings together researchers from a variety of fields to focus on emerging themes and concepts in 'Autophagy, Inflammation, and Immunity'. Key advances in this area include the identification of signaling pathways that regulate autophagy, inflammation, and immunity and the finding that inflammation, immunity and autophagy are tightly, and reciprocally, intertwined. The goal of this meeting is to relate the cell biology and signaling pathways that regulate autophagy and autophagy proteins to fundamental aspects of immunity and inflammation, as well as to diseases associated with alterations in these processes such as autoimmunity, infection, cancer, diabetes, the metabolic syndrome, and cardiovascular disease.
CME Information
Autophagy is a lysosomal degradation pathway by which eukaryotic cells break down their own components to adapt to nutrient deprivation. In multicellular organisms, autophagy and autophagy proteins also play a key role in the orchestration of diverse aspects of cellular and organismal responses to multiple dangerous stimuli, including infection. Thus, autophagy and autophagy proteins represent a key nexus within the cell through which multiple cellular and organismal stresses are integrated. This emerging understanding has led to exciting recent advances that, together, begin to paint a picture of how autophagy and autophagy proteins are involved in multiple diseases. Of particular interest, recent studies reveal a crucial role for autophagy pathways and proteins in immunity and inflammation. They balance the beneficial and detrimental effects of immunity and inflammation, and thereby may protect against infectious, autoimmune, and inflammatory diseases. The time is therefore ripe for a Keystone Symposia meeting that brings together researchers from a variety of fields to focus on emerging themes and concepts in 'Autophagy, Inflammation, and Immunity'. Key advances in this area include the identification of signaling pathways that regulate autophagy, inflammation, and immunity and the finding that inflammation, immunity and autophagy are tightly, and reciprocally, intertwined. The goal of this meeting is to relate the cell biology and signaling pathways that regulate autophagy and autophagy proteins to fundamental aspects of immunity and inflammation, as well as to diseases associated with alterations in these processes such as autoimmunity, infection, cancer, diabetes, the metabolic syndrome, and cardiovascular disease.
Conference Program Print | View meeting in 12 hr (am/pm) time
SUNDAY, FEBRUARY 17
16:00—20:00
Arrival and Registration
Alcove
07:30—08:30
Breakfast
Hochelaga 1-3
08:30—09:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
Douglas R. Green,
St. Jude Children's Research Hospital, USA
Autophagy and the Immunological Impact of Dying Cells
Autophagy and the Immunological Impact of Dying Cells
09:30—11:45
Mechanisms of Autophagy
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
Noboru Mizushima,
University of Tokyo, Graduate School of Medicine, Japan
Molecular Mechanisms of Formation of the Autophagosome and its Fusion with the Lysosome
Molecular Mechanisms of Formation of the Autophagosome and its Fusion with the Lysosome
Mark J. Daly,
Harvard Medical School, USA
Autophagy Genes in Human Disease
Autophagy Genes in Human Disease
Takanori Otomo,
The Scripps Research Institute, USA
Short Talk: Structure of the Human ATG12~ATG5 Conjugate Required for LC3 Lipidation in Autophagy
Short Talk: Structure of the Human ATG12~ATG5 Conjugate Required for LC3 Lipidation in Autophagy
10:10—10:30
Coffee Break
Hochelaga 1-3
11:45—13:00
Poster Setup
Hochelaga 1-3
13:00—22:00
Poster Viewing
Hochelaga 1-3
11:45—16:30
On Own for Lunch and Recreation
14:30—16:30
Workshop
Le Grand Salon
*
Ken H. Cadwell,
New York University School of Medicine, USA
*
Eun-Kyeong Jo,
Chungnam National University, South Korea
Jamaal Benjamin,
University of Texas Southwestern Medical Center, USA
Epithelial Cell Autophagy in Antibacterial Defense of the Small Intestine
Epithelial Cell Autophagy in Antibacterial Defense of the Small Intestine
Juliane Becher,
Santa Lucia Foundation, Italy
AMBRA1 is Upregulated during T Cell Stimulation to Avoid Excessive Proliferation and Stabilizes the Regulatory T Cell Phenotype
AMBRA1 is Upregulated during T Cell Stimulation to Avoid Excessive Proliferation and Stabilizes the Regulatory T Cell Phenotype
Tiffany Horng,
Harvard School of Public Health, USA
A Critical Role for Calcium Mobilization in Activation of the NLRP3 Inflammasome
A Critical Role for Calcium Mobilization in Activation of the NLRP3 Inflammasome
Rhea M. Sumpter, Jr.,
University of Texas Southwestern Medical Center, USA
FANCC Is a Novel Selective Autophagy Factor
FANCC Is a Novel Selective Autophagy Factor
Audrey Esclatine,
INSERM, France
A Viral Protein Represses Autophagy by Interacting with the Protein Kinase PKR
A Viral Protein Represses Autophagy by Interacting with the Protein Kinase PKR
You-Wen He,
Duke University Medical Center, USA
Inositol Phosphatases and Class I PI3K Synergize to Induce Autophagy in T Cells
Inositol Phosphatases and Class I PI3K Synergize to Induce Autophagy in T Cells
Jane Symington,
Washington University in St. Louis, USA
ATG16L1 Regulates Host Defense to Uropathogenic Escherichia coli Infection by Controlling Macrophage-Mediated Bacterial Clearance
ATG16L1 Regulates Host Defense to Uropathogenic Escherichia coli Infection by Controlling Macrophage-Mediated Bacterial Clearance
Ingo Schmitz,
Otto von Guericke University Magdeburg, Germany
The Gadd45beta-MEKK4-p38 Pathway Mediates Phosphorylation of Atg5 and Autophagy Inhibition
The Gadd45beta-MEKK4-p38 Pathway Mediates Phosphorylation of Atg5 and Autophagy Inhibition
16:30—17:00
Coffee Available
Hochelaga 1-3
17:00—19:00
Selective Autophagy and Infection
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
*
Sharon A. Tooze,
London Research Institute, UK
Ivan Dikic,
Goethe University Medical School, Germany
Structure-Function Analysis of Selective Autophagy Receptors
Structure-Function Analysis of Selective Autophagy Receptors
Michael J. Ragusa,
NIDDK, National Institutes of Health, USA
Short Talk: Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis
Short Talk: Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis
Jeffery S. Cox,
University of California, San Francisco, USA
The Ubiquitin Ligase PARKIN Is Required for Autophagy and Host Resistance to Intracellular Pathogens
The Ubiquitin Ligase PARKIN Is Required for Autophagy and Host Resistance to Intracellular Pathogens
Yuuki Fujiwara,
National Institute of Neuroscience, NCNP, Japan
Short Talk: A Novel Type of Autophagy that Targets RNA
Short Talk: A Novel Type of Autophagy that Targets RNA
19:00—20:00
Social Hour w/ Lite Bites
Hochelaga 1-3
19:30—22:00
Poster Session 1
Hochelaga 1-3
07:30—08:30
Breakfast
Hochelaga 1-3
08:00—08:30
Poster Setup
Hochelaga 1-3
08:30—17:00
Poster Viewing
Hochelaga 1-3
08:30—11:45
Autophagy and Infection
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
*
Jenny P. Y. Ting,
University of North Carolina at Chapel Hill, USA
Pascale Cossart,
Institut Pasteur, France
Autophagy and the Cytoskeleton: Links Revealed by Cytosolic Bacteria
Autophagy and the Cytoskeleton: Links Revealed by Cytosolic Bacteria
Robert L. Modlin,
University of California, Los Angeles, USA
Vitamin D, Autophagy and Tuberculosis
Vitamin D, Autophagy and Tuberculosis
Beth Levine,
University of Texas Southwestern Medical Center, USA
A Candidate Therapeutic Autophagy-Inducing Peptide for Viral Infections
A Candidate Therapeutic Autophagy-Inducing Peptide for Viral Infections
Fulvio Reggiori,
University Medical Centre Utrecht, Netherlands
Coronaviruses Hijack LC3-I-Positive EDEMosome Membranes for Replication
Coronaviruses Hijack LC3-I-Positive EDEMosome Membranes for Replication
Augustine H. Choy,
Yale University, USA
Short Talk: The Legionella Effector RavZ Inhibits Host Autophagy through Irreversible Atg8 Deconjugation
Short Talk: The Legionella Effector RavZ Inhibits Host Autophagy through Irreversible Atg8 Deconjugation
Eun-Kyeong Jo,
Chungnam National University, South Korea
Short Talk: AMP-Activated Protein Kinase Activator AICAR Activates Innate Host Defense through Antibacterial Autophagy and Mitochondrial Biogenesis
Short Talk: AMP-Activated Protein Kinase Activator AICAR Activates Innate Host Defense through Antibacterial Autophagy and Mitochondrial Biogenesis
09:50—10:10
Coffee Break
Hochelaga 1-3
11:45—12:30
Lunch
Hochelaga 1-3
12:30—15:00
Poster Session 2
Hochelaga 1-3
15:00—15:30
Coffee Available
Hochelaga 1-3
15:30—17:30
Autophagy and Immunity
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
*
Augustine Choi,
Harvard Medical School, USA
Herbert (Skip) W. Virgin,
Washington University School of Medicine, USA
Autophagy Proteins and Macrophage-Based Immunity to Infection
Autophagy Proteins and Macrophage-Based Immunity to Infection
Vojo Deretic,
University of New Mexico Health Sciences Center, USA
Autophagy Protects Against Active Tuberculosis by Suppressing Bacterial Burden and Inflammation
Autophagy Protects Against Active Tuberculosis by Suppressing Bacterial Burden and Inflammation
Tatsuya Saitoh,
Osaka University, Japan
Regulation of Inflammatory Innate Immune Response by Autophagy-Related Protein
Regulation of Inflammatory Innate Immune Response by Autophagy-Related Protein
Amanda Marchiando,
New York University School of Medicine, USA
Short Talk: Atg16L1 Mutation Protects Against Bacterial Gastroenteritis
Short Talk: Atg16L1 Mutation Protects Against Bacterial Gastroenteritis
17:30—
On Own for Dinner
07:30—08:30
Breakfast
Hochelaga 1-3
08:30—11:45
Autophagy and the Inflammasome
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
*
Lora V. Hooper,
University of Texas Southwestern Medical Center, USA
Gökhan S. Hotamisligil,
Harvard University, USA
Metabolic Inflammasome and Mechanisms of Immunometabolic Integration
Metabolic Inflammasome and Mechanisms of Immunometabolic Integration
Jenny P. Y. Ting,
University of North Carolina at Chapel Hill, USA
NLRs, Inflammasome and Autophagy
NLRs, Inflammasome and Autophagy
Nobuhiko Kayagaki,
Genentech, Inc., USA
The Non-Canonical Inflammasome and Caspase 11
The Non-Canonical Inflammasome and Caspase 11
Catherine Gidley Weindel,
Tufts University Sackler School of Biomedical Sciences, USA
Short Talk: Autophagy: A Dichotomous Player in TLR7-Mediated Autoimmunity
Short Talk: Autophagy: A Dichotomous Player in TLR7-Mediated Autoimmunity
Miguel A. Sanjuan,
Medimmune/Astrazeneca, USA
Short Talk: LC3-Associated Phagocytosis Mediates IFN-alpha Secretion in Response to DNA-Immune Complexes
Short Talk: LC3-Associated Phagocytosis Mediates IFN-alpha Secretion in Response to DNA-Immune Complexes
09:50—10:10
Coffee Break
Hochelaga 1-3
11:45—13:00
Poster Setup
Hochelaga 1-3
13:00—22:00
Poster Viewing
Hochelaga 1-3
11:45—16:30
On Own for Lunch and Recreation
16:30—17:00
Coffee Available
Hochelaga 1-3
17:00—19:00
Autophagy and Inflammatory Signaling
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
*
Eileen P. White,
Rutgers University, USA
Masaaki Komatsu,
Tokyo Metropolitan Institute of Medical Science, Japan
Selective Autophagy Is Coupled to Nrf2-Keap1 Pathway
Selective Autophagy Is Coupled to Nrf2-Keap1 Pathway
Jorge Moscat,
Sanford-Burnham Medical Research Institute, USA
p62: A Multifunctional Signaling Molecule in Inflammation and Metabolism
p62: A Multifunctional Signaling Molecule in Inflammation and Metabolism
Sergio Grinstein,
Hospital for Sick Children, Canada
Phospholipids Mediate Immune Surveillance by Macrophages and Dendritic Cells
Phospholipids Mediate Immune Surveillance by Macrophages and Dendritic Cells
Christina Bell,
Université de Montréal, Canada
Short Talk: Quantitative Proteomics Reveals the Specific Autophagic Elimination of Mitochondria in TNF-alpha Activated Macrophages
Short Talk: Quantitative Proteomics Reveals the Specific Autophagic Elimination of Mitochondria in TNF-alpha Activated Macrophages
19:00—20:00
Social Hour w/ Lite Bites
Hochelaga 1-3
19:30—22:00
Poster Session 3
Hochelaga 1-3
07:30—08:30
Breakfast
Hochelaga 1-3
08:30—11:45
Autophagy in Metabolic and Inflammatory Disease
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
*
Vojo Deretic,
University of New Mexico Health Sciences Center, USA
Clay F. Semenkovich,
Washington University School of Medicine, USA
Autophagy, Atherosclerosis, and the Metabolic Syndrome
Autophagy, Atherosclerosis, and the Metabolic Syndrome
Lora V. Hooper,
University of Texas Southwestern Medical Center, USA
Intestinal Epithelial Cell Autophagy and the Microbiota
Intestinal Epithelial Cell Autophagy and the Microbiota
Thaddeus S. Stappenbeck,
Washington University School of Medicine, USA
Autophagy Proteins and Regulation of Intestinal Homeostasis
Autophagy Proteins and Regulation of Intestinal Homeostasis
Assaf Rudich,
Ben-Gurion University, Israel
Short Talk: Transcriptional Basis for Inflammatory Activation of Adipose Tissue Autophagy in Obesity
Short Talk: Transcriptional Basis for Inflammatory Activation of Adipose Tissue Autophagy in Obesity
Donna M. Conlon,
Columbia University, USA
Short Talk: Inhibition of VLDL Secretion by Apolipoprotein B Antisense Oligonucleotides Stimulates Autophagy of Endoplasmic Reticulum in the Liver, Preventing Steatosis
Short Talk: Inhibition of VLDL Secretion by Apolipoprotein B Antisense Oligonucleotides Stimulates Autophagy of Endoplasmic Reticulum in the Liver, Preventing Steatosis
09:50—10:10
Coffee Break
Hochelaga 1-3
11:45—16:30
On Own for Lunch and Recreation
16:30—17:00
Coffee Available
Hochelaga 1-3
17:00—19:15
Autophagy in Inflammatory Disease and Cancer
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Le Grand Salon
*
Noboru Mizushima,
University of Tokyo, Graduate School of Medicine, Japan
Ramnik Xavier,
Massachusetts General Hospital and Broad Institute, USA
Autophagy Genes and Inflammatory Bowel Disease
Autophagy Genes and Inflammatory Bowel Disease
Heinz Jungbluth,
Newcomen Centre at St. Thomas', St. Thomas' Hospital, UK
Vici Syndrome, a Novel Multisystem Disorder Associated with Defective Autophagy
Vici Syndrome, a Novel Multisystem Disorder Associated with Defective Autophagy
Eileen P. White,
Rutgers University, USA
Autophagy in Tumor Cell Survival
Autophagy in Tumor Cell Survival
Guido Kroemer,
Institut Gustave Roussy, France
Autophagy-Dependent Anti-Tumor Immunity
Autophagy-Dependent Anti-Tumor Immunity
19:15—20:15
Social Hour w/ Lite Bites
Hochelaga 1-3
20:00—23:00
Entertainment
Hochelaga 1-3
Departure
*Session Chair †Speaker invited, not yet responded.
Keystone Symposia thanks our Sponsors for generously supporting this meeting:
|
|
|
|
|
|
We gratefully acknowledge additional support for this conference from:
|
|
We gratefully acknowledge support for this conference from:
We gratefully acknowledge the generous grant for this conference provided by:
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
Click here to view more of these organizations
|
If your organization is interested in joining these entities in support of Keystone
Symposia, please contact: Melissa Carrera, Assistant
Director of Development, Email: MelissaC@keystonesymposia.org, Phone:+1 970-262-2679 Click here for more information on Industry Support and Recognition Opportunities. If you are interested in becoming an advertising/marketing in-kind partner, please contact: Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org, Phone:+1 970-262-2676 |
