Oberstdorf Haus Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2014


Here are the related meetings in 2018:
Chromatin Architecture and Chromosome Organization (X5)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Chromatin Mechanisms and Cell Physiology (C5)


Organizer(s) Thomas Jenuwein and Shelley L. Berger
March 23—28, 2014
Oberstdorf Haus • Oberstdorf, Germany
Discounted Abstract Deadline: Nov 20, 2013
Abstract Deadline: Dec 19, 2013
Scholarship Deadline: Nov 20, 2013
Discounted Registration Deadline: Jan 22, 2014

Sponsored by Bayer HealthCare Pharmaceuticals, Constellation Pharmaceuticals and the German Ministry of Education and Research (BMBF).

Summary of Meeting:
Chromatin is the physiological form of DNA in eukaryotic cells and thus serves as a template for many basic DNA related processes (e.g., transcription, repair, replication, recombination). Dynamic changes in chromatin structure are essential for the organization and utilization of our genetic information and are mediated by epigenetic mechanisms such as histone/DNA modifications, non-coding RNAs and chromatin remodeling. The establishment, maintenance and plasticity of distinct chromatin states are crucial for embryonic development, cell differentiation and cell type identity, as well as allowing response to environmental cues such as hormones, stress or nutrients. Chromatin dysfunction also significantly contributes to cell transformation and perturbed development. This Keystone meeting will highlight novel findings in mechanisms of dynamic chromatin regulation and their translation into cellular physiology. In particular, we will focus on four fundamental chromatin processes (RNA regulation, transcription and remodeling, DNA damage and repair, DNA replication) in conjunction with normal and perturbed cellular states (cell fate, signal response, cell transformation, epigenetic inheritance). Sessions feature basic and applied research in model systems ranging from plants to fungi to mammals. This open and inclusive program should generate intense discussions, interesting synergies and a strong bridge connecting basic chromatin research with cellular physiology. This link is beneficial to further explore the dynamic (mis)-regulation of chromatin-based processes in medically relevant research fields investigating complex human disorders or stem cell therapy.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, MARCH 23

16:00—20:00
Arrival and Registration

Foyer
18:00—20:00
Welcome Mixer

Foyer

MONDAY, MARCH 24

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Chromatin Modifications
Meeting has ended...abstracts no longer viewable online.

Nebelhorn
Anjana Rao, La Jolla Institute for Allergy and Immunology, USA
TET Proteins and 5-Methylcytosine Oxidation

* Ali Shilatifard, Northwestern University, USA
Enhancer Malfunction in Cancer

Henk G. Stunnenberg, Radboud University, Netherlands
Epigenomics: Functional Indexing Genomes in Health and Disease

Asifa Akhtar, Max Planck Institute of Immunobiology and Epigenetics, Germany
Epigenetic Regulation of the X Chromosome

Jörn Walter, Saarland University, Germany
DNA Methylation and the Shaping of the Epigenome

09:50—10:10
Coffee Break

Foyer
11:45—13:00
Poster Setup

Nebelhorn
13:00—22:00
Poster Viewing

Nebelhorn
11:45—14:30
On Own for Lunch and Recreation

14:30—16:30
Panel: Epigenetic Inheritance

Nebelhorn
* Shelley L. Berger, University of Pennsylvania, USA

Bradley R. Cairns, HHMI/University of Utah, USA

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Cell Fate
Meeting has ended...abstracts no longer viewable online.

Nebelhorn
* Geneviève Almouzni, Centre National de la Recherche Scientifique, France

Alexander Meissner, Max Planck Institute for Molecular Genetics, Germany
DNA Methylation Dynamics in Stem Cells and Development

Azim Surani, University of Cambridge, UK
Germline – Specification and Epigenetic Programming

Amanda G. Fisher, MRC Clinical Sciences Centre, Imperial College London, UK
Human X Chromosome Reactivation by Cell Fusion Reprogramming

Maria-Elena Torres-Padilla, Helmholtz Centre Munich, Germany
Short Talk: Novel Chromatin Pathways to Induce Totipotency

19:00—20:00
Social Hour with Lite Bites

Breitachklamm
19:30—22:00
Poster Session 1

Nebelhorn

TUESDAY, MARCH 25

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Transcription and Chromatin Remodeling
Meeting has ended...abstracts no longer viewable online.

Nebelhorn
* Amanda G. Fisher, MRC Clinical Sciences Centre, Imperial College London, UK

Bradley R. Cairns, HHMI/University of Utah, USA
The Regulation of Chromatin Remodeling ATPases

Huck-Hui Ng, Genome Institute of Singapore, Singapore
Transcriptional Regulatory Networks in Embryonic Stem Cells

Geneviève Almouzni, Centre National de la Recherche Scientifique, France
Nucleosome Dynamics and Histone Variants

Jerry L. Workman, Stowers Institute for Medical Research, USA
Histone Modification and Exchange during Gene Transcription: Signals and Mechanisms

Armelle Corpet, University Hospital Zürich, Switzerland
Short Talk: Daxx-Dependent Targeting of New H3.3 to PML Bodies in Proliferating and Senescent Cells

Julie Ahringer, University of Cambridge, UK
Short Talk: Extreme HOT Regions Are CpG Dense Promoters in C. elegans and Humans

09:50—10:10
Coffee Break

Foyer
11:45—13:00
Poster Setup

Nebelhorn
13:00—22:00
Poster Viewing

Nebelhorn
11:45—17:00
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Signal Response
Meeting has ended...abstracts no longer viewable online.

Nebelhorn
* Nicholas J. Proudfoot, University of Oxford, UK

Paolo Sassone-Corsi, University of California, Irvine, USA
Mammalian Circadian Clock and Metabolism: The Epigenetic Link

Katrin F. Chua, Stanford University Medical Center, USA
Chromatin Regulation and Genome Maintenance by Mammalian SIRT6 and SIRT7

Ari M. Melnick, Weill Cornell Medical College, USA
IDH Mutations in Leukemia

Anna T. Rolicka, University of Warsaw, Poland
Short Talk: DELLA-Interacting SWI3C Core Subunit of SWI/SNF Chromatin Remodeling Complex Modulates Gibberellin Responses and Hormonal Crosstalk in Arabidopsis

19:00—20:00
Social Hour with Lite Bites

Breitachklamm
19:30—22:00
Poster Session 2

Nebelhorn

WEDNESDAY, MARCH 26

07:30—08:30
Breakfast

Individual Hotel
08:00—08:30
Poster Setup

Nebelhorn
08:30—19:00
Poster Viewing

Nebelhorn
08:30—11:30
RNA Regulation
Meeting has ended...abstracts no longer viewable online.

Nebelhorn
* Edith Heard, Institut Curie, France

Shiv I. S. Grewal, NCI, National Institutes of Health, USA
Nuclear RNA Processing and Facultative Heterochromatin Assembly

Peter J. Thompson, University of British Columbia, Canada
Short Talk: hnRNP K Mediates SETDB1-Dependent Proviral and Gene Repression in ES Cells

Nicholas J. Proudfoot, University of Oxford, UK
Mechanisms of RNA Polymerase II Termination in Protein Coding and lncRNA Genes

Ramin Shiekhattar, University of Miami, USA
Long Noncoding RNAs with Enhancer-Like Function in Human Cells

Robert Schneider, Institut de Biologie Moléculaire et Cellulaire, IBMC, France
Short Talk: H2B Methylation, a Guardian of Transposable Elements

Federica Federici, Erasmus MC, Netherlands
Short Talk: Round Spermatid Injection and X Chromosome Inactivation in Mouse Female Embryos

09:50—10:10
Coffee Break

Foyer
11:30—12:30
Lunch

Breitachklamm
12:00—14:30
Poster Session 3

Nebelhorn
14:30—16:30
Workshop: Epigenetic Therapy/Inhibitors

Nebelhorn
* Thomas Jenuwein, Max Planck Institute of Immunobiology and Epigenetics, Germany

Eugene Yue Dao Chua, Nanyang Technological University, Singapore
Nucleosomal DNA Sequence-Dependent Properties and Targeting by Novel Platinum-Intercalator Species

Paul Fields, University of Washington, USA
H2A.Z Functionally Interacts with Tandem Bromodomain Proteins to Activate Genes during ESC Differentiation

Ruri Kaneda, Jichi Medical University, Japan
Histone Methyltransferase Inhibitor Improves Prognosis in Chronic Heart Failure: Analysis of Histone H3 Lysine 9 Methylation-Status on Repetitive loci

Kathryn E. Malecek, University of Chicago, USA
Identification and Characterization of Oxidized Methylcytosine Binding Activity in Mammalian Brain

Anne Schaefer, Mount Sinai School of Medicine, USA
PRC2 Is Essential for Neuronal Function and Survival

Emma Nilsson, Lund University, Sweden
Genome-Wide Analyses of DNA Methylation and mRNA Expression in Adipose Tissue from Monozygotic Twin Pairs Discordant for Type 2 Diabetes

Alessio Zippo, Fondazione Istituto Nazionale de Genetica Molecolare-INGM, Italy
MYC Sustains the Wnt Autocrine Loop of ESC by Inducing Epigenetic Silencing of DKK1 and SFRP1 via PRC2 Recruitment

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Cell Transformation
Meeting has ended...abstracts no longer viewable online.

Nebelhorn
* Job Dekker, University of Massachusetts Medical School, USA

Alexander Tarakhovsky, Rockefeller University, USA
Signaling Function of Polycomb

Tony Kouzarides, University of Cambridge, UK
Epigenetic Modifications in Transcription and Cancer

Toshikazu Ushijima, National Cancer Center Research Institute, Japan
Induction Mechanism of Aberrant Epigenetic Modifications by Chronic Inflammation

Panagiotis Ntziachristos, Northwestern University, USA
Short Talk: Dissecting Important Roles of H3K27 Demethylases in T Cell Leukemia

19:00
On Own for Dinner


THURSDAY, MARCH 27

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Chromatin Organization
Meeting has ended...abstracts no longer viewable online.

Nebelhorn
* Huck-Hui Ng, Genome Institute of Singapore, Singapore

Bas van Steensel, Netherlands Cancer Institute, Netherlands
Single-Cell Dynamics of Genome - Nuclear Lamina Interactions

Thomas Jenuwein, Max Planck Institute of Immunobiology and Epigenetics, Germany
Interstitial Heterochromatin in the Mouse Embryonic Stem Cell Epigenome Is Defined by Suv39h-Dependent H3K9me3

Job Dekker, University of Massachusetts Medical School, USA
Chromosome Folding and Gene Regulation

Edith Heard, Institut Curie, France
Dynamic Genomic and Epigenomic Landscapes: Lessons from the X-Inactivation Centre

Florian A. Steiner, University of Geneva, Switzerland
Short Talk: Holocentromeres Are Dispersed Point Centromeres Localized at Transcription Factor Hotspots

Nabieh Ayoub, Technion University, Israel
Short Talk: Misregulation of KDM4A-D Histone Demethylases Promotes Chromosomal Instability

09:50—10:10
Coffee Break

Foyer
11:45—17:00
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Foyer
17:00—19:15
Epigenetic Inheritance
Meeting has ended...abstracts no longer viewable online.

Nebelhorn
* Paolo Sassone-Corsi, University of California, Irvine, USA

Danny F. Reinberg, HHMI/New York University, USA
Polycomb Complexes

Shelley L. Berger, University of Pennsylvania, USA
Profound Chromatin Changes in Eukaryotic Senescence and Relationship to Aging and Cancer

Minoo Rassoulzadegan, Université de Nice, France
RNA-Mediated Heredity of Paramutation and Acquired Phenotype in the Mouse

Eric L. Greer, Harvard Medical School, Boston Children's Hospital, USA
A Histone Methylation Network Regulates Transgenerational Epigenetic Memory in C. elegans

Sarah Kimmins, McGill University, Canada
Short Talk: KDM1A/LSD1 Is Essential for Spermtogonial Stem Cell Differentiation and Survival

19:00—20:00
Social Hour with Lite Bites

Breitachklamm
20:00—23:00
Entertainment

Breitachklamm

FRIDAY, MARCH 28

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Bayer HealthCare Pharmaceuticals Constellation Pharmaceuticals
German Ministry of Education and Research (BMBF)
 

We gratefully acknowledge additional support for this conference from:

Abcam plc Bethyl Laboratories, Inc.
Cell Signaling Technology, Inc.
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

EMBO (European Molecular Biology Organization)

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676