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Santa Fe Community Convention Center Floorplan
This meeting took place in 2013
Here are the related meetings in 2014:
Adult Neurogenesis (E1)
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
Neurogenesis (J7)
Organizer(s) Hongjun Song, Yukiko Gotoh, Yi Eve Sun and Gerd Kempermann
February 3—8, 2013
Santa Fe Community Convention Center • Santa Fe, New Mexico USA
Abstract Deadline: Oct 4, 2012
Late Abstract Deadline: Nov 1, 2012
Scholarship Deadline: Oct 4, 2012
Early Registration Deadline: Dec 4, 2012
Sponsored by Genentech, Inc., Pfizer Inc. and Shire Human Genetic Therapies
Joint Meeting:
New Frontiers in Neurodegenerative Disease Research (J8)
Summary of Meeting:
Formation of the nervous system starts with neurogenesis from neural stem cells in the developing embryo and continues throughout life in discrete regions of the adult brain. Defects in developing and adult neurogenesis have been implicated in various mental disorders and degenerative neurological diseases. In recent years, tremendous progress has been made in understanding the cellular and molecular mechanism regulating neurogenesis from neural stem cells/progenitors in the developing and adult brain. This meeting will gather an interdisciplinary group of scientists using various experimental model systems to highlight the latest advances in the neurogenesis field, including understanding of novel genetic and epigenetic mechanisms regulating developing and adult neurogenesis, disease modeling using patient-derived induced pluripotent stem cells, and identification of potential functions of adult neurogenesis and its contribution to mental disorder and degenerative neurological disorders. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent Keystone Symposia meeting on New Frontiers in Neurodegenerative Disease Research, which will share two plenary sessions with this meeting. In combination, these meetings will provide a platform for both speakers and participants to initiate extensive discussion and promote scientific collaborations on new directions.
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Formation of the nervous system starts with neurogenesis from neural stem cells in the developing embryo and continues throughout life in discrete regions of the adult brain. Defects in developing and adult neurogenesis have been implicated in various mental disorders and degenerative neurological diseases. In recent years, tremendous progress has been made in understanding the cellular and molecular mechanism regulating neurogenesis from neural stem cells/progenitors in the developing and adult brain. This meeting will gather an interdisciplinary group of scientists using various experimental model systems to highlight the latest advances in the neurogenesis field, including understanding of novel genetic and epigenetic mechanisms regulating developing and adult neurogenesis, disease modeling using patient-derived induced pluripotent stem cells, and identification of potential functions of adult neurogenesis and its contribution to mental disorder and degenerative neurological disorders. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent Keystone Symposia meeting on New Frontiers in Neurodegenerative Disease Research, which will share two plenary sessions with this meeting. In combination, these meetings will provide a platform for both speakers and participants to initiate extensive discussion and promote scientific collaborations on new directions.
View Scholarships/Awards
Conference Program Print | View meeting in 12 hr (am/pm) time
SUNDAY, FEBRUARY 3
08:00—09:00
Welcome and Keynote Address
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*
Hongjun Song,
Johns Hopkins University School of Medicine, USA
Fred H. Gage,
The Salk Institute for Biological Studies, USA
Neurogenesis and Neurological Disorders: Lessons from Studies of Adult Neurogenesis and Patient-Derived iPSCs
Neurogenesis and Neurological Disorders: Lessons from Studies of Adult Neurogenesis and Patient-Derived iPSCs
08:00—09:00
Welcome and Keynote Address
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*
Li-Huei Tsai,
Massachusetts Institute of Technology, USA
Susan Lindquist,
HHMI/Whitehead Institute for Biomedical Research, USA
Modeling Pathology in Simpler Cells
Modeling Pathology in Simpler Cells
09:00—11:15
Neurogenesis and Gliogenesis
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Patrik Ernfors,
Karolinska Institutet, Sweden
Neurogenesis and Cell-Type Diversification in the Sympathetic Lineage
Neurogenesis and Cell-Type Diversification in the Sympathetic Lineage
Federico Calegari,
Dresden University of Technology, CRTD, Germany
Short Talk: Transcriptomes of Proliferating Neural Stem Cells
Short Talk: Transcriptomes of Proliferating Neural Stem Cells
Edmund Au,
New York University Medical Center, USA
Short Talk: Directed Differentiation of ES Cells to Cortical Interneurons Demonstrates that LMO3 Biases Subtype Identity
Short Talk: Directed Differentiation of ES Cells to Cortical Interneurons Demonstrates that LMO3 Biases Subtype Identity
Rebecca D. Hodge,
University of Washington, USA
Short Talk: Tbr2 Expression in Cajal-Retzius Cells and Intermediate Neuronal Progenitors Is Required for Morphogenesis of the Dentate Gyrus
Short Talk: Tbr2 Expression in Cajal-Retzius Cells and Intermediate Neuronal Progenitors Is Required for Morphogenesis of the Dentate Gyrus
09:00—11:00
Protein Aggregation and Propagation of Misfolded Proteins in the Brain
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Virginia M.-Y. Lee,
University of Pennsylvania School of Medicine, USA
Alpha-Synuclein Transmission in Parkinson’s Disease
Alpha-Synuclein Transmission in Parkinson’s Disease
Jeffery W. Kelly,
The Scripps Research Institute, USA
Adapting the Chemical and or Biology of Protein Homeostasis to Ameliorate Aggregation-Associated Diseases
Adapting the Chemical and or Biology of Protein Homeostasis to Ameliorate Aggregation-Associated Diseases
17:00—19:00
Model Systems
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*
Christopher A. Walsh,
Children's Hospital Boston, USA
Arnold R. Kriegstein,
University of California, San Francisco, USA
OSVZ Neurogenesis in the Developing Human Neocortex
OSVZ Neurogenesis in the Developing Human Neocortex
Su-Chun Zhang,
University of Wisconsin-Madison, USA
Neural Subtype Specification from Human Pluripotent Stem Cells
Neural Subtype Specification from Human Pluripotent Stem Cells
Simon Hippenmeyer,
Institute of Science and Technology Austria, Austria
Short Talk: Tracing Neurogenesis in Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)
Short Talk: Tracing Neurogenesis in Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)
Ryan P. Stadel,
Johns Hopkins University School of Medicine, USA
Short Talk: Coexistence of Quiescent and Active Radial Neural Stem Cell Populations in the Adult Hippocampus
Short Talk: Coexistence of Quiescent and Active Radial Neural Stem Cell Populations in the Adult Hippocampus
17:00—19:00
Mechanisms of Early Disease Intervention and Biomarkers
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*
Michael Hutton,
Eli Lilly Research Center, UK
John Q. Trojanowski,
University of Pennsylvania, USA
Tau Biomarkers, Transmission and Therapies
Tau Biomarkers, Transmission and Therapies
Rosa Rademakers,
Mayo Clinic, USA
Non-Coding Repeat Expansions in C9ORF72 as a Novel Cause of Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
Non-Coding Repeat Expansions in C9ORF72 as a Novel Cause of Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
Cristian A. Lasagna-Reeves,
Baylor College of Medicine, USA
Short Talk: Ataxin-1 Amyloid Oligomers Form in a Mouse Model of Spinocerebellar Ataxia Type 1 and Correlate with Disease Pathogenesis
Short Talk: Ataxin-1 Amyloid Oligomers Form in a Mouse Model of Spinocerebellar Ataxia Type 1 and Correlate with Disease Pathogenesis
Kelly T. Dineley,
University of Texas Medical Branch, USA
Short Talk: pERK-PPARgamma Protein Complexes In AD Cognitive Enhancement
Short Talk: pERK-PPARgamma Protein Complexes In AD Cognitive Enhancement
Jessica L. Larson,
Genentech, Inc., USA
Short Talk: A Meta-Analysis of Inflammation Gene Sets in Neurodegenerative Disease
Short Talk: A Meta-Analysis of Inflammation Gene Sets in Neurodegenerative Disease
08:00—11:00
Neurogenesis and Development: Molecular Mechanisms
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*
Yi Eve Sun,
University of California, Los Angeles, USA
Yukiko Gotoh,
University of Tokyo, Japan
Regulation of Neural Precursor Cell Fate in the Developing Mouse Neocortex
Regulation of Neural Precursor Cell Fate in the Developing Mouse Neocortex
Soo-Kyung Lee,
Oregon Health & Science University, USA
Gene Regulatory Networks in Spinal Cord Neurogenesis
Gene Regulatory Networks in Spinal Cord Neurogenesis
Francois Guillemot,
National Institute for Medical Research, UK
Regulation of Stem Cell Divisions in the Adult Brain
Regulation of Stem Cell Divisions in the Adult Brain
Jenny Hsieh,
University of Texas Southwestern Medical Center at Dallas, USA
Activity-Dependent Gene Transcription in Adult Neurogenesis
Activity-Dependent Gene Transcription in Adult Neurogenesis
Sven Falk,
Helmholtz Center Munich, Germany
Short Talk: Smad4 and Trim33 Redundantly Regulate Neural Stem Cells in the Developing Cortex
Short Talk: Smad4 and Trim33 Redundantly Regulate Neural Stem Cells in the Developing Cortex
Felipe Mora-Bermúdez,
Max Planck Institute of Molecular Cell Biology and Genetics, Germany
Short Talk: Distinct Populations of Mitotic Microtubules Regulate Mammalian Neurogenesis
Short Talk: Distinct Populations of Mitotic Microtubules Regulate Mammalian Neurogenesis
08:00—11:00
Molecular Mechanisms of Neuronal Vulnerability
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*
Rosa Rademakers,
Mayo Clinic, USA
*
Ronald B. DeMattos,
Lilly Research Laboratories, USA
Valina L. Dawson,
Johns Hopkins University School of Medicine, USA
Mechanisms of Cell Death in Neurodegeneration
Mechanisms of Cell Death in Neurodegeneration
Amber L. Southwell,
University of British Columbia, Canada
Selective Mutant Huntingtin Gene Silencing
Selective Mutant Huntingtin Gene Silencing
Sarah E. Dougherty,
University of Alabama at Birmingham, USA
Short Talk: Restricted Expression of Mutant Huntingtin to Parvalbumin-Positive Cell Populations Causes Hyperactivity and Altered Synaptic Function in the Motor Cortex
Short Talk: Restricted Expression of Mutant Huntingtin to Parvalbumin-Positive Cell Populations Causes Hyperactivity and Altered Synaptic Function in the Motor Cortex
Eric J. Huang,
University of California, San Francisco, USA
Role of RNA/DNA Binding Protein FUS in Neurodegeneration
Role of RNA/DNA Binding Protein FUS in Neurodegeneration
Keith W. Crosby,
University of Florida, USA
Short Talk: Immunophenotyping of Transgenic Mouse Models of CNS Proteinopathies
Short Talk: Immunophenotyping of Transgenic Mouse Models of CNS Proteinopathies
14:30—16:30
Workshop (Joint): iPSC Technologies and their Application
*
Fred H. Gage,
The Salk Institute for Biological Studies, USA
Introduction
Introduction
*
Su-Chun Zhang,
University of Wisconsin-Madison, USA
Introduction
Introduction
Anita Bhattacharyya,
University of Wisconsin-Madison, USA
Deficits in Human Trisomy 21 iPSCs and Neurons: A Model for Down Syndrome Intellectual Disability
Deficits in Human Trisomy 21 iPSCs and Neurons: A Model for Down Syndrome Intellectual Disability
Beatriz C. Freitas,
University of California, San Diego, USA
Contribution of Human Astrocytes to Rett Syndrome
Contribution of Human Astrocytes to Rett Syndrome
Marisa Karow,
Ludwig Maximilian University of Munich, Germany
Reprogramming of Pericyte-Derived Cells of the Adult Human Brain into Induced Neuronal Cells
Reprogramming of Pericyte-Derived Cells of the Adult Human Brain into Induced Neuronal Cells
17:00—19:00
Stem Cell Niches in the Developing and Adult Brain
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*
Yukiko Gotoh,
University of Tokyo, Japan
Christopher A. Walsh,
Children's Hospital Boston, USA
Intrinsic and Extrinsic Control of Neurogenesis in the Cerebral Cortex
Intrinsic and Extrinsic Control of Neurogenesis in the Cerebral Cortex
Chay T. Kuo,
Duke University School of Medicine, USA
Sustaining New Neuron Production in the SVZ Niche
Sustaining New Neuron Production in the SVZ Niche
Sebastian Jessberger,
University of Zürich, Switzerland
EMBO Young Investigator Programme Lecture: Metabolic Control of Adult Neural Stem/Progenitor Cell Activity
EMBO Young Investigator Programme Lecture: Metabolic Control of Adult Neural Stem/Progenitor Cell Activity
Sohyun Ahn,
NICHD, National Institutes of Health, USA
Short Talk: Gli3 Repressor Interacts with the Numb and gp130/STAT3 Pathways to Promote the Establishment of the Postnatal Neural Stem Cell Niche
Short Talk: Gli3 Repressor Interacts with the Numb and gp130/STAT3 Pathways to Promote the Establishment of the Postnatal Neural Stem Cell Niche
Stephen C. Noctor,
University of California, Davis, USA
Short Talk: Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex
Short Talk: Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex
17:00—19:00
Novel Approaches for the Therapeutic Intervention of Neurodegenerative Disease
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*
André Fischer,
German Center for Neurodegenerative Diseases, Germany
Michael Hutton,
Eli Lilly Research Center, UK
Towards an Understanding of tau Pathology Propagation and Spreading
Towards an Understanding of tau Pathology Propagation and Spreading
Anders Bjorklund,
Lund University, Sweden
Nurr1 as Target for Neuroprotection and Therapeutic Intervention in Parkinson's Disease
Nurr1 as Target for Neuroprotection and Therapeutic Intervention in Parkinson's Disease
Ronald B. DeMattos,
Lilly Research Laboratories, USA
The Development of Abeta Target Specific Immunotherapies for AD
The Development of Abeta Target Specific Immunotherapies for AD
Pierre Drapeau,
University of Montréal, Canada
Short Talk: Chemical Genetic Screens of TARDBP and FUS Modifiers in C. elegans and Zebrafish Models of ALS
Short Talk: Chemical Genetic Screens of TARDBP and FUS Modifiers in C. elegans and Zebrafish Models of ALS
Rebecca Canter,
Massachusetts Institute of Technology, USA
Short Talk: Increased Cholinergic Activity Restores Memory Function in a Mouse Model of AD
Short Talk: Increased Cholinergic Activity Restores Memory Function in a Mouse Model of AD
08:00—11:00
Epigenetics and Genomics (Joint)
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*
Bruce A. Yankner,
Harvard Medical School, USA
Yi Eve Sun,
University of California, Los Angeles, USA
Single Cell Transcriptome Analyses Reveal Secrets of the Adult Neurogenic Zone
Single Cell Transcriptome Analyses Reveal Secrets of the Adult Neurogenic Zone
André Fischer,
German Center for Neurodegenerative Diseases, Germany
Epigenetic Mechanisms in Dementia
Epigenetic Mechanisms in Dementia
Daniel H. Geschwind,
University of California, Los Angeles, USA
Functional Genomic Analyses of Pathways Dysregulated in Frontal Temporal Dementia
Functional Genomic Analyses of Pathways Dysregulated in Frontal Temporal Dementia
Hongjun Song,
Johns Hopkins University School of Medicine, USA
Neuronal Activity-Induced Changes of DNA Methylome in Neurons
Neuronal Activity-Induced Changes of DNA Methylome in Neurons
Johan Holmberg,
Karolinska Institutet, Sweden
Short Talk: A Key Role for the Chromatin Remodeler CHD5 for Neuronal Differentiation and Tumor Suppression in the Nervous System
Short Talk: A Key Role for the Chromatin Remodeler CHD5 for Neuronal Differentiation and Tumor Suppression in the Nervous System
Matthew L. Eaton,
Massachusetts Institute of Technology, USA
Short Talk: Genome-Wide Analysis of DNA Methylation and Genotype in 750 Individuals Reveals Global Regulatory Changes in Brain Enhancers Associated with Alzheimer’s Disease
Short Talk: Genome-Wide Analysis of DNA Methylation and Genotype in 750 Individuals Reveals Global Regulatory Changes in Brain Enhancers Associated with Alzheimer’s Disease
17:00—19:00
Adult Neurogenesis: Regulation and Functions
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*
Fred H. Gage,
The Salk Institute for Biological Studies, USA
Matthew T. Valley,
Pasteur Institute, France
Adult-Born Neurons Integrate Behavioral States
Adult-Born Neurons Integrate Behavioral States
Gerd Kempermann,
Technische Universität Dresden, Germany
Benefits from Newborn Neurons in the Adult Hippocampus
Benefits from Newborn Neurons in the Adult Hippocampus
Shaoyu Ge,
SUNY Stony Brook, USA
Optogenetic Probing for the Development and Function of Adult-Born Neurons
Optogenetic Probing for the Development and Function of Adult-Born Neurons
Cristina V. Dieni,
University of Alabama at Birmingham, USA
Short Talk: Sparse Excitatory Innervation Provides High Input Specificity to Adult-Born Neurons
Short Talk: Sparse Excitatory Innervation Provides High Input Specificity to Adult-Born Neurons
Mazen A. Kheirbek,
Columbia University, USA
Short Talk: Control of Learning and Anxiety by Mature and Immature Granule Cells of the Dentate Gyrus
Short Talk: Control of Learning and Anxiety by Mature and Immature Granule Cells of the Dentate Gyrus
17:00—19:00
Aging and Genome Integrity
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*
Li Gan,
Gladstone Institutes, USA
Bruce A. Yankner,
Harvard Medical School, USA
Modeling the Role of Genomic Instability in Aging and Alzheimer’s Disease
Modeling the Role of Genomic Instability in Aging and Alzheimer’s Disease
Peter J. McKinnon,
St. Jude Children's Research Hospital, USA
DNA Damage Signaling and Neurogenesis
DNA Damage Signaling and Neurogenesis
Li-Huei Tsai,
Massachusetts Institute of Technology, USA
Genome Integrity, Chromatin Remodeling and Neurodegenerative Disorders
Genome Integrity, Chromatin Remodeling and Neurodegenerative Disorders
08:00—11:00
Adult Neurogenesis under Pathological Conditions
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*
Gerd Kempermann,
Technische Universität Dresden, Germany
Xinyu Zhao,
University of Wisconsin-Madison, USA
Adult Neurogenesis and Neurodevelopmental Disorders
Adult Neurogenesis and Neurodevelopmental Disorders
Heather A. Cameron,
NIMH, National Institutes of Health, USA
Adult Neurogenesis, Stress and Depression
Adult Neurogenesis, Stress and Depression
Randall R. Reed,
Johns Hopkins University, USA
Maintenance and Regeneration of Olfactory Neurons
Maintenance and Regeneration of Olfactory Neurons
Jack M. Parent,
University of Michigan, USA
Adult Neurogenesis and Epilepsy
Adult Neurogenesis and Epilepsy
Beate Winner,
The Salk Institute, Fau Erlangen-Nurnberg, USA
Short Talk: Alpha-Synuclein in Neuronal Maturation and Adult Neurogenesis in the Dentate Gyrus
Short Talk: Alpha-Synuclein in Neuronal Maturation and Adult Neurogenesis in the Dentate Gyrus
Caroline R. McKeown,
The Scripps Research Institute, USA
Short Talk: Neurogenesis is Required for Behavioral Recovery after Injury in the Visual System of Xenopus laevis
Short Talk: Neurogenesis is Required for Behavioral Recovery after Injury in the Visual System of Xenopus laevis
08:00—11:00
Neurobiology of Disease
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*
Valina L. Dawson,
Johns Hopkins University School of Medicine, USA
David M. Holtzman,
Washington University, USA
Sleep and Alzheimer’s Disease: Potential Cellular, Molecular, and Network Connections
Sleep and Alzheimer’s Disease: Potential Cellular, Molecular, and Network Connections
Ted M. Dawson,
Johns Hopkins University School of Medicine, USA
Understanding Molecular Mechanisms of Neurodegeneration in Parkinson’s Disease
Understanding Molecular Mechanisms of Neurodegeneration in Parkinson’s Disease
Paula D. Ladd,
University of Washington, USA
Short Talk: Expanding the Transcriptomes at Unstable Tandem Repeat Loci
Short Talk: Expanding the Transcriptomes at Unstable Tandem Repeat Loci
Aimee W. Kao,
University of California, San Francisco, USA
Short Talk: Progranulin and Granulin: Reciprocal Modulators of Organismal Stress Response
Short Talk: Progranulin and Granulin: Reciprocal Modulators of Organismal Stress Response
Li Gan,
Gladstone Institutes, USA
Pathogenic Events Triggered by Tau Acetylation in Neurodegeneration
Pathogenic Events Triggered by Tau Acetylation in Neurodegeneration
Ryan J. Watts,
Genentech, Inc., USA
Targeting Neurodegeneration by Boosting Antibody Uptake in Brain
Targeting Neurodegeneration by Boosting Antibody Uptake in Brain
17:00—19:00
iPSC Modeling of Developmental and Degenerative Neurological Diseases (Joint)
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*
Li-Huei Tsai,
Massachusetts Institute of Technology, USA
*
Hongjun Song,
Johns Hopkins University School of Medicine, USA
Guo-li Ming,
Johns Hopkins University, USA
Understanding Functions of Schizophrenia Susceptibility Genes using Pluripotent Human Stem Cells
Understanding Functions of Schizophrenia Susceptibility Genes using Pluripotent Human Stem Cells
Gabsang Lee,
Johns Hopkins University School of Medicine, USA
Discovery of Potential Therapeutic Compounds with Patient-Specific and Symptom-Relevant Neural Crest Derived from Familial Dysautonomia-iPSC
Discovery of Potential Therapeutic Compounds with Patient-Specific and Symptom-Relevant Neural Crest Derived from Familial Dysautonomia-iPSC
Stephen J. Haggarty,
Harvard Medical School, Massachusetts General Hospital, USA
Probing Neuroplasticity Pathways in Neuropsychiatric Disorders with Patient Specific Stem Cell Models & Small Molecules
Probing Neuroplasticity Pathways in Neuropsychiatric Disorders with Patient Specific Stem Cell Models & Small Molecules
Helen Fong,
University of California, San Francisco, USA
Short Talk: Modeling Tauopathies Using Isogenic Human Induced Pluripotent Stem Cells
Short Talk: Modeling Tauopathies Using Isogenic Human Induced Pluripotent Stem Cells
Sandra Almeida,
University of Massachusetts Medical School, USA
Short Talk: Induced Pluripotent Stem Cell Models of Frontotemporal Dementia
Short Talk: Induced Pluripotent Stem Cell Models of Frontotemporal Dementia
*Session Chair †Speaker invited, not yet responded.
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