Registered Attendees

Registered Attendees

Print This Page

Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Close Window
Big Sky Resort Floorplan

Big Sky Resort Floorplan

Print This Page



Close Window

This meeting took place in 2014


Here are the related meetings in 2015:
Gut Microbiota Modulation of Host Physiology: The Search for Mechanism (C1)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Exploiting and Understanding Chemical Biotransformations in the Human Microbiome (D1)


Organizer(s) Peter J. Turnbaugh, Curtis Huttenhower and Michael A. Fischbach
April 1—6, 2014
Big Sky Resort • Big Sky, Montana USA
Discounted Abstract Deadline: Dec 5, 2013
Abstract Deadline: Jan 9, 2014
Scholarship Deadline: Dec 5, 2013
Discounted Registration Deadline: Feb 3, 2014

Supported by the Directors' Fund

Summary of Meeting:
The aggregate genomes of the trillions of microorganisms associated with the human body, the gut microbiome, extend our own human metabolism through transforming our diet and xenobiotic compounds, including host-targeted drugs and antibiotics. Furthermore, our microbial consortia encode a diverse array of biosynthetic machinery, making them an ideal source of novel natural products. This conference explores the major challenges that are emerging from this new area of study: 1) The biotransformation and resistance to therapeutics; 2) The discovery of natural products from microorganisms, in the context of the human microbiome and other systems; 3) Computational approaches to understanding microbial metabolism and biosynthesis; 4) The potential for synthetic biology to engineer microbiomes; 5) Therapeutic approaches to manipulate the microbiome; 6) Host-microbial signaling mechanisms; and 7) The consequences of microbial biotransformations and toxicity on host health and disease. This conference should foster long-lasting collaborative partnerships between individuals with wide-ranging expertise from both academia and industry. It incorporates the introduction of state-of-the-art techniques to existing areas of research, along with an attempt to identify general biological themes that influence multiple areas of research.

View Scholarships/Awards

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, APRIL 1

16:00—20:00
Arrival and Registration
18:00—20:00
Mixer

WEDNESDAY, APRIL 2

07:00—08:00
Breakfast
08:00—09:00
Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Michael A. Fischbach, University of California, San Francisco, USA

Elaine Holmes, Imperial College London, UK
Trans-Omic Communication in Development and Control of Obesity

09:00—11:30
Microbial Interactions with Therapeutics
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Gerry D. Wright, McMaster University, Canada
Bacterial Inactivation of Anticancer Drugs

Matthew R. Redinbo, University of North Carolina at Chapel Hill, USA
Safely and Selectively Modulating the Mammalian Microbiome

Peter J. Turnbaugh, Harvard University, USA
Contributions of the Human Gut Microbiome to Drug Metabolism

Arik Alper, Yale University, USA
Short Talk: The Impact of Human Gut Microbial Community Variation on 5-ASA Metabolism

Libusha Kelly, Albert Einstein College of Medicine, USA
Short Talk: Diverse and Mobile beta-Glucuronidases Populate Healthy Human Guts

09:40—10:00
Coffee Break
11:30—12:45
NIH Resources and Funding Opportunities to Support Microbiome-Related Research
The goals of the session are (1) to provide an overview of NIH programs, resources, and funding opportunities to support research on understanding how the microbiome contributes to health and disease and (2) to provide a forum for participants to meet and interact with NIH program officials through discussion.

The workshop will include an introduction and brief presentations by NIH program staff on specific programs and funding opportunities, followed by discussions where participants can interact with NIH program staff in small groups.

* Padma Maruvada, NIDDK, National Institutes of Health, USA

11:30—13:00
Poster Setup
13:00—22:00
Poster Viewing
12:45—17:00
On Own for Lunch and Recreation
16:30—17:00
Coffee Available
17:00—19:00
Biosynthesis of Small Molecules and Drug Discovery
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Gerry D. Wright, McMaster University, Canada

Emily P. Balskus, Harvard University, USA
Discovery and Characterization of Disease-Associated Metabolic Pathways within the Human Gut Microbiota

Michael A. Fischbach, University of California, San Francisco, USA
Insights from a Global View of Secondary Metabolism: Small Molecules from the Human Microbiota

Philip P. Strandwitz, Northeastern University, USA
Short Talk: GABA Is a Growth Factor for Uncultured Bacteria from the Human Gut Microbiome

19:00—20:00
Social Hour with Lite Bites
19:30—22:00
Poster Session 1

THURSDAY, APRIL 3

07:00—08:00
Breakfast
08:00—11:15
Computational Approaches to Understanding Microbial Metabolism and Biosynthesis
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Aleksandar David Kostic, Broad Institute, USA

Elhanan Borenstein, University of Washington, USA
Metegenomic Systems Biology: Toward a Predictive Systems-Level Model of the Human Microbiome

João B. Xavier, Memorial Sloan-Kettering Cancer Center, USA
Modeling Intestinal Microbiota Dynamics during Antibiotic Treatment

Curtis Huttenhower, Harvard School of Public Health, USA
Multi'omic Characterization of the Gut Microbial Ecosystem for Diagnosis and Therapy in Inflammatory Disease

Rob Knight, University of Colorado, USA
Microbial Communities Viewed Over Time and Space

Patrick H. Bradley, Gladstone Institutes, USA
Short Talk: Assessing the Stability of Protein Family Abundance in the Gut Microbiome

Dan B. Knights, University of Minnesota, USA
Short Talk: Linking Complex Host Genetics to Bacterial Dysbiosis in Inflammatory Bowel Disease

09:20—09:40
Coffee Break
11:15—13:00
Poster Setup
13:00—22:00
Poster Viewing
11:15—14:30
On Own for Lunch and Recreation
13:30—16:30
Workshop: Bioinformatics Tools (a Tutorial)
* Curtis Huttenhower, Harvard School of Public Health, USA
HUMAnN v2/ShortBRED

Morgan Langille, Dalhousie University, Canada
PICRUSt/STAMP

Elhanan Borenstein, University of Washington, USA
Metabolic Modeling

Rob Knight, University of Colorado, USA
Evident/Qiita

16:30—17:00
Coffee Available
17:00—19:00
Impacts on Host Health and Disease
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Heidi H. Kong, NCI, National Institutes of Health, USA

Christian Jobin, University of Florida, USA
Interaction between Genotoxic Bacteria and Host Environment Influences Colorectal Cancer Development

Stanley L. Hazen, Cleveland Clinical Foundation, USA
Links between Microbial Metabolism of Dietary Choline and Atherosclerosis

Eugene B. Chang, University of Chicago, USA
Diet, Microbes and Genetics: The Perfect Storm to Inflammatory Bowel Diseases

Elaine Y. Hsiao, California Institute of Technology, USA
Short Talk: A Commensal Bacterium of the Gut Microbiome Modulates Serum Metabolites and Ameliorates Behavioral Abnormalities in a Mouse Model of an Autism Risk Factor

19:00—20:00
Social Hour with Lite Bites
19:30—22:00
Poster Session 2

FRIDAY, APRIL 4

07:00—08:00
Breakfast
08:00—11:00
Engineering Microbiomes
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Curtis Huttenhower, Harvard School of Public Health, USA

Sean Davies, Vanderbilt University, USA
Genetically Engineered Therapeutic Bacteria

Christopher Voigt, Massachusetts Institute of Technology, USA
Synthetic Metagenomics

Tom Van de Wiele, Ghent University, Belgium
Simulating the Human Gut Microbiome

Liang Ma, California Institute of Technology, USA
Short Talk: Using Microfluidics for Genetically Targeted Cultivation Validated by Isolation of a “Most Wanted” Microbe from the Human Gut

Yannan Zhao, The Scripps Research Institute, USA
Short Talk: Self-Assembling Cyclic Peptides for Modulating the Gut Microbiome to Treat Atherosclerosis

09:20—09:40
Coffee Break
11:00—13:00
Poster Setup
13:00—22:00
Poster Viewing
11:00—17:00
On Own for Lunch and Recreation
16:30—17:00
Coffee Available
17:00—19:15
Therapeutics Approaches to Manipulating the Microbiome
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Matthew R. Redinbo, University of North Carolina at Chapel Hill, USA

Nathalie Delzenne, Université Catholique de Louvain, Belgium
Prebiotic Approach: A Nutrition-Based Therapy to Tackle Metabolic Diseases Related to Malnutrition

Alexander Khoruts, University of Minnesota, USA
Human Fecal Microbiota Transplantation in Treatment of Clostridium difficile Infection: Metabolic Effects of Engraftment

Petra Louis, University of Aberdeen, UK
Dietary Modulation of the Gut Microbiota and Metabolism

Liping Zhao, Shanghai Jiao Tong University, China
Can We Follow Koch's Postulates for Hunting Down Human Obesity Bugs in Gut Microbiota?

19:15—20:15
Social Hour with Lite Bites
19:30—22:00
Poster Session 3

SATURDAY, APRIL 5

07:00—08:00
Breakfast
08:00—11:15
Host-Microbial Interactions
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Elaine Y. Hsiao, California Institute of Technology, USA

Heidi H. Kong, NCI, National Institutes of Health, USA
Host-Microbial Interactions in Healthy Skin and Dermatologic Disorders

Margaret J. McFall-Ngai, , USA
Evolutionarily Conserved Signals of Host-Microbe Interaction: Lessons from the Squid-Vibrio Symbiosis

Katherine P. Lemon, Forsyth Institute, USA
Nose Picking for Progress: Mining Nasal Microbiota for New Insights into Pathobionts

Sven Pettersson, Karolinska Institutet, Sweden
The Maternal Microbiome Influence Placenta Development and Function which can Influence Brain Function Later in Life

Charisse Petersen, University of Utah, USA
Short Talk: Direct Detection of the Microbiota by T Cells Prevents Pathobiont Expansion to Maintain Homeostasis

Tim D. Spector, King's College London, UK
Short Talk: Host Genetic Control of the Human Gut Microbiome: A Twin Study

09:20—09:40
Coffee Break
11:15—17:00
On Own for Lunch and Recreation
16:30—17:00
Coffee Available
17:00—18:15
Unintended Consequences of Antibiotic Use
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Peter J. Turnbaugh, Harvard University, USA

Tami Lieberman, Harvard Medical School, USA
Genomic Evolution and Diversification of a Pathogen within the Patient

Martin J. Blaser, New York University School of Medicine, USA
Early Life Exposure to Antibiotics Changes Developmental Phenotypes

18:15—19:15
Closing Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

David A. Relman, Stanford University, USA
Stability and Resilience in the Human Microbiome

19:15—20:15
Social Hour with Lite Bites
20:00—23:00
Entertainment

SUNDAY, APRIL 6

 
Departure

*Session Chair †Invited, not yet responded.



We gratefully acknowledge additional support for this conference from:

Crohn's & Colitis Foundation of America Integrated DNA Technologies

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 5R13DK084688-05

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

EMBO (European Molecular Biology Organization)

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Amanda Deem, Assistant Director of Development, Email: AmandaD@keystonesymposia.org,
Phone:+1 970-262-2668

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676