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Fairmont Banff Springs Floorplan

Fairmont Banff Springs Floorplan

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This meeting took place in 2014


Here are the related meetings in 2015:
Mechanisms of HIV Persistence: Implications for a Cure (E1)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

HIV Pathogenesis – Virus vs. Host (X4)


Organizer(s) J. Victor Garcia-Martinez, Daria J. Hazuda and Dan R. Littman
March 9—14, 2014
Fairmont Banff Springs • Banff, Alberta Canada
Discounted Abstract Deadline: Nov 7, 2013
Abstract Deadline: Dec 11, 2013
Scholarship Deadline: Nov 7, 2013
Discounted Registration Deadline: Jan 10, 2014

Sponsored by Gilead Sciences, Inc. Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation


Summary of Meeting:
This meeting is focused on the latest breakthroughs in basic and translational HIV research with an emphasis on mechanistic models. It presents a detailed tour of all the key steps of virus replication from infection to AIDS. The program seamlessly incorporates key aspects of HIV biology including: 1) Virus entry/exit into/from the cell; 2) Entry into the host; 3) Virus-host genetics and co-evolution; 4) Virus-host interactions and responses; 5) Pathogenesis; 6) Reservoirs, latency and reactivation; and 7) HIV and the microbiome at the mucosa. Strong emphasis will be given to these and other areas well represented in the abstracts submitted. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on “HIV Vaccines: Adaptive Immunity and Beyond,” which shares opening and closing keynote addresses and two plenary sessions with this meeting.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, MARCH 9

16:00—20:00
Arrival and Registration

16:30—18:00
Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endgame
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

NOTE: Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.


MONDAY, MARCH 10

07:00—08:00
Breakfast

08:00—09:00
Opening Addresses (Joint)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Nicole Frahm, Fred Hutchinson Cancer Research Center, USA

* J. Victor Garcia-Martinez, University of North Carolina, USA

Myron S. Cohen, University of North Carolina at Chapel Hill, USA
Integrated HIV Prevention Strategies: High Time for a Synergistic Approach

Carl W. Dieffenbach, NIAID, National Institutes of Health, USA
The Big Questions: The Basic Research Progress Needed to Help Control the HIV/AIDS Pandemic

09:00—11:30
Portals of Entry and Sites of Dissemination (Joint)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* James A. Hoxie, University of Pennsylvania, USA

* Thomas Musich, DHHS, USA

J. Victor Garcia-Martinez, University of North Carolina, USA
Mechanistic Analysis of Vaginal HIV Transmission and Prevention

Peter A. Anton, David Geffen School of Medicine at UCLA, USA
Rectal HIV Transmission

Ashley T. Haase, University of Minnesota, USA
Virus-Host Immune Interactions at the Portal of Entry and Vaccine Design to Prevent HIV-1 Transmission to Women

Thomas J. Hope, Northwestern University, Feinberg School of Medicine, USA
Short Talk: Hotspots of SIV Infection in the Female Reproductive Tract after Vaginal Exposure of Rhesus macaques to Single Round Dual Reporter Vector

Samuel K. Lai, University of North Carolina at Chapel Hill, USA
Short Talk: Influence of Vaginal Microbiota on the Diffusional Barrier Properties of Cervicovaginal Mucus against HIV

09:40—10:00
Coffee Break

11:30—13:00
Poster Setup

13:00—22:00
Poster Viewing

11:30—14:30
On Own for Lunch and Recreation

14:30—16:30
Workshop 1: Role of Animal Models for HIV Research

* Roberto F. Speck, University of Zurich, Switzerland

* Frank Kirchhoff, University of Ulm, Germany

Atef F. Allam, Walter Reed Institute of Research, USA
Characterization of B- and T Cells in the Gut Mucosa of Humanized DRAG Mice During HIV Infection

Timothy E. Dudek, Ragon Institute of MGH, MIT and Harvard, USA
Immunization of Humanized BLT Mice Against HIV Influences Early Immune Responses and Viral Loads

Yanhui Cai, Tulane National Primate Research Center, USA
SIV Infection of Lung Interstitial Macrophages Contributes to Tissue Damage and Inflammatory Responses in the Lung

Christopher A. Gaulke, University of California, Davis, USA
SIV Induced Disruption of microRNA Expression in the Small Intestine Contributes to Epithelial Barrier Dysfunction

Jung Joo Hong, Emory University, YNPRC, USA
Early Lymphoid Responses and Germinal Center Formation Correlates with Lower Viral Load Set Points and Better Prognosis of SIV Infection

Luca Micci, Emory University, YNPRC, USA
Interleukin-21 Reduces Residual Immune Activation in ART-Suppressed SIV-Infected Rhesus macaques by Restoring Intestinal Th17 and Th22 Cells

M. Christine Zink, Johns Hopkins University, USA
Sustained Upregulation of Neurotoxic Kynurenine Pathway Metabolites in cART-Treated SIV-Infected Pigtailed Macaques: Impact on Neuroinflammation and Serotonin Metabolism

Adrienne E. Swanstrom, University of Pennsylvania, USA
In Vivo Evaluation of a Novel Variant of SIVmac Lacking CD4 Tropism

14:30—16:30
Workshop 1: Mucosal Immunity

* Marjorie Robert-Guroff, NCI, National Institutes of Health, USA

* Thomas J. Hope, Northwestern University, Feinberg School of Medicine, USA

Liang Shang, University of Minnesota, USA
Immune Complex – Fc Receptor Interactions Reduce Inflammatory Responses at the Genital Mucosa as a Correlate of SIV Vaccine-Induced Protection

Yichuan Wang, NCI, National institutes of Health, USA
Vaginal Type-II Mucosa Acts as an Inductive Site for the Generation of Primary CD8+ T Cell Mucosal Immune Responses

Genoveffa Franchini, NCI, National Institutes of Health, USA
Modulation of the RAS Pathways as a Biomarker of Protection Against HIV and as a Means to Improve Vaccine Efficacy

Rena D. Astronomo, Fred Hutchinson Cancer Research Center, USA
Neutrophils May Provide Front-Line Antibody Effector Functions in the Cervical But Not the Vaginal Mucosa

Béhazine Combadière, INSERM, France
Cutaneous Routes for HIV Vaccination Strategies

Sampa Santra, Harvard Medical School, USA
Simian-Human Immunodeficiency Viruses with Transmitted/Founder Clade C HIV-1 Envelopes

Thorsten Demberg, NCI, National Institutes of Health, USA
Phenotyping and Characterization of Mucosal Memory B-Cell Populations in the SIV/SHIV Rhesus macaque Model

Thomas Musich, DHHS, USA
Purification and Functional Characterization of Mucosal IgA from Vaccinated and SIV-Infected Rhesus macaques

15:30—17:00
Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endgame
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

NOTE: Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.

15:30—17:00
Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endgame
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

NOTE: Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.

16:30—17:00
Coffee Available

17:00—19:15
Host-Viral Co-Evolution
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Quentin J. Sattentau, Sir William Dunn School of Pathology, UK

* Doris Wilflingseder, Innsbruck Medical University, Austria

Welkin E. Johnson, Boston College, USA
Genetic Barriers to Cross-Species Transmission and Emergence of Primate Immunodeficiency Viruses

Robert J. Gifford, University of Glasgow, UK
The Evolution and Emergence of Lentiviral Pandemics since the Neolithic Era

Viviana Simon, Icahn School of Medicine at Mount Sinai, USA
Short Talk: HIV Evolution in Humanized Mice

Li Wu, Ohio State University, USA
Short Talk: Identification of Cellular Proteins Interacting with the Retroviral Restriction Factor SAMHD1

Thijs Booiman, University of Amsterdam, Netherlands
Short Talk: The Effect of Genetic Variation in Trex1 on HIV-1 Disease Progression and in vitro HIV-1 Replication

Angelique Hoelzemer, Ragon Institute of MGH, MIT and Harvard, USA
Short Talk: Selection of a Distinct HIV-1 p24 Gag Sequence Polymorphism in KIR2DL3/HLA-C*03:04+ Individuals Is Associated with Viral Escape from Recognition by KIR2DL3+ NK Cells

17:00—19:15
Programming Durable Immunity
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Rafael Cubas, Vaccine and Gene Therapy Institute Florida, USA

* Hendrik Streeck, Military HIV Research Program, USA

Robert A. Seder, NIAID, National Institutes of Health, USA
Development of a Malaria Vaccine: A Parable of Vaccine Delivery, Breadth of Antigens and Effector Cells

Mark K. Slifka, Oregon National Primate Research Center, Oregon Health & Science University, USA
Potential Mechanisms for Sustaining Long-Term Humoral Immunity

Shane Crotty, La Jolla Institute for Allergy and Immunology, USA
Tfh Cells and Memory Tfh Cells

Diego J. Farfán-Arribas, University of Massachusetts Medical School, USA
Short Talk: Evidence on the Involvement of Germinal Centers and T Follicular Helper Cells in DNA Immunization for HIV Vaccine Development

Ann J. Hessell, Oregon Health & Science University, USA
Short Talk: Cross-Clade Neutralizing Antibodies and Envelope-Specific TFH Cell Responses Are Elicited in Macaques Co-Immunized with DNA and Protein Env Vaccines Derived from Multiple Subjects during Development of Breadth

19:15—20:15
Social Hour with Lite Bites

19:30—22:00
Poster Session 1


TUESDAY, MARCH 11

07:00—08:00
Breakfast

07:30—08:00
Poster Setup

08:00—19:00
Poster Viewing

08:00—11:15
Viral Entry/Exit and Host Genetics
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Eric Hunter, Emory University, USA

* Gilda Tachedjian, Burnet Institute, Australia

Wesley I. Sundquist, University of Utah School of Medicine, USA
HIV Assembly and Egress

Vineet N. KewalRamani, NCI, National Institutes of Health, USA
HIV Entry and Nuclear Translocation

Fadila Bouamr, NIAID, National Institutes of Health, USA
The Host and HIV Exit

Janice E. Clements, Johns Hopkins University, USA
Macrophages Contribute to the Latent Viral Reservoir in Tissues of cART Suppressed SIV-Infected Macaques

Peijun Zhang, University of Pittsburgh, USA
Short Talk: Structural Mechanisms of HIV-1 Capsid Assembly and Maturation

Amy Hulme, Northwestern University, USA
Short Talk: Viral and Cellular Factors Affect HIV-1 Uncoating

08:00—11:00
Inducing Protective Immunity
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Anne-Sophie M. Dugast, Ragon Institute of MGH, MIT and Harvard, USA

* Adrian B. McDermott, National Institutes of Health, USA

William H. Robinson, Stanford University School of Medicine, USA
Protective B Cell Responses

Gabriel D. Victora, Whitehead Institute for Biomedical Research, USA
Cellular Dynamics and Clonal Selection in the Germinal Center

Jonathan W. Yewdell, NIAID, National Institutes of Health, USA
Translating Information for MHC Class Immunosurveillance

Susan W. Barnett, Novartis Vaccines and Diagnostics, Inc., USA
Non-Viral Delivery of Self-Amplifying mRNA: A Versatile Synthetic Vaccine Platform for HIV

Kelly D. Moynihan, Massachusetts Institute of Technology, USA
Short Talk: Lymph-Node Targeting of Molecular Vaccines through “Albumin Hitchhiking”

Joseph G. Jardine, The Scripps Research Institute, USA
Short Talk: Design of Germline-Targeted Immunogens with Enhanced Breadth for VRC01-Class Precursors

09:20—09:40
Coffee Break

11:15—12:00
Lunch

12:00—14:30
Poster Session 2

14:30—16:30
Panel 1: HIV/AIDS: Strategies for an Endgame (Joint)

* Carl W. Dieffenbach, NIAID, National Institutes of Health, USA

Galit Alter, Ragon Institute of MGH, MIT and Harvard, USA

Peter A. Anton, David Geffen School of Medicine at UCLA, USA

Myron S. Cohen, University of North Carolina at Chapel Hill, USA

Magdalena E. Sobieszczyk, Columbia University, USA

David M. Margolis, University of North Carolina at Chapel Hill, USA

Thomas C. Quinn, NIAID and Johns Hopkins University, USA

16:30—17:00
Coffee Available

17:00—19:00
Mechanistic Models of Pathogenesis and Disease
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Heinrich Gottlinger, University of Massachusetts Medical School, USA

* Shokrollah Elahi, University of Alberta, Canada

Richard T. D'Aquila, Northwestern University, USA
APOBEC3s versus Vif-Positive HIV-1: Tipping the Balance toward Virus Control

Timothy W. Schacker, University of Minnesota, USA
The Natural History of HIV Infection in Lymphatic Tissues

Anthony L. Cunningham, Westmead Millennium Institute, University of Sydney, Australia
Short Talk: HIV Inhibits Interferon Production in Macrophages and Dendritic Cells but Exerts Other Antiviral Mechanisms

Anna Aldovini, Boston Children's Hospital and Harvard Medical School, USA
Short Talk: HIV-1 Tat Engagement of Different Promoters in Different Cell Types Results in Apoptosis of CD4+ T Cells and Activation of ISG Linked to Immune Activation in Antigen Presenting Cells

17:00—19:15
Tackling Global HIV Diversity
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Richard A. Koup, NIAID, National Institutes of Health, USA

* Edward A. Berger, NIAID, National Institutes of Health, USA

Beatrice H. Hahn, University of Pennsylvania, USA
Phenotypic Properties of Transmitted Founder HIV-1

Bette T. Korber, Los Alamos National Laboratory, USA
Using Signatures of Neutralizing Antibodies to Inform Vaccine Design

Andrew B. Ward, The Scripps Research Institute, USA
High-Resolution Cryo-EM Studies of HIV-1 Env

Dan H. Barouch, Harvard Medical School/Beth Israel Deaconess Medical Center, USA
Short Talk: Prospects for Monoclonal Antibody Therapy for HIV-1

Devin Sok, The Scripps Research Institute, USA
Short Talk: Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Facilitates Broader Neutralization of HIV

19:00—
On Own for Dinner


WEDNESDAY, MARCH 12

07:00—08:00
Breakfast

08:00—11:15
Host-Virus Interactions and Responses
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Paul R. Clapham, University of Massachusetts Medical School, USA

* Jaisri R. Lingappa, University of Washington, USA

Michael Emerman, Fred Hutchinson Cancer Research Center, USA
How Ancient Host-Virus Interactions Shaped the Modern HIV-1 Pandemic in Humans

Theodora Hatziioannou, Aaron Diamond AIDS Research Center, USA
Restriction Factors and the Adaptation of HIV-1 to Non-Human Primates

Andrea Cimarelli, CIRI, International Center for Infectology Research, France
Exploring the Multiple Layers of Complexity Existing during the Early Phases of Infection of Myeloid Cells by Primate Lentiviruses

Reuben S. Harris, University of Minnesota, USA
Natural Resistance to HIV Infection by Select APOBEC3H Haplotypes

Daniel T. Claiborne, Emory University, USA
Short Talk: Protective HLA Alleles Reduce Markers of Gut Damage and Microbial Translocation and Influence Early Inflammatory Cytokine Profiles

Andre Raposo, George Washington University, USA
Short Talk: Increased Expression of Host Restriction Factors in HLA-B*57+ Individuals

08:00—11:15
Novel Mechanisms for Vaccine-Induced Protection
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Genoveffa Franchini, NCI, National Institutes of Health, USA

* Jeffrey Robert Schneider, Northwestern University, USA

Silke Paust, Baylor College of Medicine, USA
NK Memory to Experimental HIV Vaccines in Mice and Humanized Mice

Galit Alter, Ragon Institute of MGH, MIT and Harvard, USA
Fc-Signatures of Functional HIV-Specific Antibodies

Penny L. Moore, National Institute for Communicable Diseases, South Africa
Evolution of V1V2 Broad Neutralizing Antibodies during HIV-1 Infection

Louis J. Picker, Oregon Health & Science University, USA
Effector Memory T-Cell Targeted Vaccines

Susan Johnson, US Military HIV Research Program, USA
Short Talk: HIV-Specific Cytolytic CD4 T Cells Are Distinct from Th1 Cells and Preserved in HIV Infection

Anna Aldovini, Boston Children's Hospital and Harvard Medical School, USA
Short Talk: Resistance to Infection, Early and Persistent Suppression of SIVmac251 Viremia and Significant Reduction of Tissue Viral Burden after Mucosal Vaccination in Females Rhesus macaques

09:20—09:40
Coffee Break

11:15—12:45
Hands-On Computer Session on Los Alamos HIV Sequence Database

NOTE: Maximum attendance: 60. Interested participants may sign up at the meeting on a first-come, first-serve basis.

* Brian T. Foley, Los Alamos National Laboratory, USA

* Bette T. Korber, Los Alamos National Laboratory, USA

* Will Fischer, Los Alamos National Laboratory, USA

11:15—13:00
Poster Setup

13:00—22:00
Poster Viewing

12:45—14:30
On Own for Lunch and Recreation

14:30—16:30
Panel 2: Functions of Protective Antibodies

Stephen J. Kent, University of Melbourne, Australia

Margaret Ellen Ackerman, Dartmouth College, USA

Nancy L. Haigwood, Oregon Health & Science University, USA

Ruth M. Ruprecht, Texas Biomedical Research Institute, USA

James Arthos, NIAID, National Institutes of Health, USA

* Susan Zolla-Pazner, New York University School of Medicine, USA

14:30—16:30
Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CNS

* Brenda L. Fredericksen, University of Maryland, USA

* Pamela J. Skinner, University of Minnesota, USA

Joe Casazza, NIAID, National Institutes of Health, USA
Identification of HIV-Infected CD4+ T Cells using HIV RNA and Broadly Neutralizing Antibodies

Andrew N. Harman, Westmead Millennium Institute, Australia
The Role of Mucosal Dendritic Cells in HIV Infection

Rosa Camacho, Instituto Nacional de Enfermedades Respiratorias, Mexico
TNFalpha Overproduction by Conventional Dendritic Cells in Viremic versus Controller HIV Subjects

Alexandre Deshiere, Laval University, Canada
Transcriptomic and Proteomic Screening of Host Genes Modulated by HIV-1 in Human Macrophages: A Highly Sensitive Strategy for the Identification of New Susceptibility/Restriction Factors

Katharina Borm, Burnet Institute, Australia
Envelope Glycoprotein Determinants of Macrophages Tropism during Progressive HIV-1 Subtype C Infection

Maria Paz Gonzalez-Perez, University of Massachusetts Medical School, USA
HIV-1 R5 Envelopes from Brain and Immune Tissue of AIDS Patients with Normal Neurology are Less Functional and Less Macrophage-Tropic Compared to those in HAD Patients

Sheila M. Keating, Blood Systems Research Institute, USA
Cerebrospinal Fluid and Blood Inflammatory Biomarkers are Differentially Elevated in HIV and Neurological Disease

David R. Graham, Johns Hopkins School of Medicine, USA
A Combined Proteomics and Metabolomics Study of CSF from HAND Patients Under cART Therapy Reveals Evidence for Ongoing Macrophage Activation and Pertubations in Glutamate Metabolism

15:30—17:00
Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endgame
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

NOTE: Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.

16:30—17:00
Coffee Available

17:00—19:15
HIV, the Microbiome and the Mucosa
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Charles R. Rinaldo, University of Pittsburgh, USA

* John C. Tilton, Case Western Reserve University, USA

Dan R. Littman, HHMI/New York University School of Medicine, USA
Immue Homeostasis and Commensal Bacteria

Nichole R. Klatt, University of Washington, USA
Kinetics of Mucosal Dysfunction after SIV Infection of Rhesus macaques

Satya Dandekar, University of California, Davis, USA
HIV Pathogenesis: The GALT

Brent E. Palmer, University of Colorado Health Sciences Center, USA
Short Talk: Alterations in the Gut Microbiota Associated with HIV Infection

Hannah J. Barbian, University of Pennsylvania, USA
Short Talk: Evaluating the Enteric Virome as a Marker of Disease Progression in SIVcpz Infected Wild-Living Chimpanzees

17:00—19:15
Engineering Protective Immune Responses
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Rena D. Astronomo, Fred Hutchinson Cancer Research Center, USA

* Mark Connors, NIAID, National Institutes of Health, USA

William Schief, IAVI and The Scripps Research Institute, USA
Vaccines to Induce Broadly Neutralizing Antibodies

Nicholas M. Valiante, Novartis Vaccines and Diagnostics, USA
Minimal Essential Adjuvants: A Rational Approach for Optimizing Small Molecules as Vaccine Adjuvants

Mario Roederer, NIAID, National Institutes of Health, USA
Antigenic Heterogeneity of Clonal Envelopes: A Novel Immune Evasion Mechanism

Louise Scharf, California Institute of Technology, USA
Short Talk: A New Site of Broad Vulnerability on the HIV-1 Envelope Spike Defined by a Patient-Derived Antibody

19:15—20:15
Social Hour with Lite Bites

19:30—22:00
Poster Session 3


THURSDAY, MARCH 13

07:00—08:00
Breakfast

08:00—11:15
Reservoirs, Latency, Reactivation and Eradication
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Robert W. Buckheit, Jr., ImQuest BioSciences, Inc., USA

* Linda Chelico, University of Saskatchewan, Canada

Daria J. Hazuda, Merck Research Laboratories, USA
New Drug Targets in the Search for an HIV Cure

David M. Margolis, University of North Carolina at Chapel Hill, USA
HIV Eradication Approaches

Hiroyu Hatano, University of California, San Francisco, USA
HIV Persistence in "Elite" Controllers

Steven M. Wolinsky, Northwestern University, USA
Persistent HIV-1 Replication and Evolution in Drug Sanctuaries within Peripheral Lymphoid Organ Compartments in Patients on Combination Antiretroviral Therapy

Edward A. Berger, NIAID, National Institutes of Health, USA
Short Talk: Novel CD4-Based Chimeric Antigen Receptors: Toward an HIV Functional Cure Using Genetically Modified CD8+ T Cells

Scott G. Kitchen, David Geffen School of Medicine at UCLA, UCLA AIDS Institute, USA
Short Talk: Engineering Stem Cells with Chimeric Antigen Receptors for HIV-Specific T Cell Immunity

08:00—11:15
From Concepts to Implementation
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Liang Shang, University of Minnesota, USA

* William A. Paxton, Institute of Infection and Global Health, UK

Nicole Frahm, Fred Hutchinson Cancer Research Center, USA
Immunogenicity of HIV Vaccine Candidates in the HIV Vaccine Trials Network (HVTN)

Magdalena E. Sobieszczyk, Columbia University, USA
Lessons from HVTN 505 Efficacy Trial of a DNA/rAd5 HIV Preventive Vaccine

Jerome H. Kim, Walter Reed Army Institute of Research, USA
RV144 and HIV Acquisition: Insights and New Questions

Thomas C. Quinn, NIAID and Johns Hopkins University, USA
The Impact of Combination Prevention on the HIV Pandemic

Susan Zolla-Pazner, New York University School of Medicine, USA
Short Talk: IgG V3-Specific Antibody (Ab) Reactivity in Plasma from RV144: Implications for Vaccine Efficacy

Iskra Tuero, NCI, National Institutes of Health, USA
Short Talk: SIV Trimeric versus Monomeric Env-Induced Antibodies and Delayed SIV Acquisition in Vaccinated Female Rhesus macaques

09:20—09:40
Coffee Break

11:15—12:45
Hands-On Computer Session on Los Alamos HIV Immunology Database

NOTE: Maximum attendance: 60. Interested participants may sign up at the meeting on a first-come, first-serve basis.

* Brian T. Foley, Los Alamos National Laboratory, USA

* Bette T. Korber, Los Alamos National Laboratory, USA

* Will Fischer, Los Alamos National Laboratory, USA

12:45—15:30
On Own for Lunch and Recreation

14:30—16:30
Panel 3: Triggering Protective B-Cell Responses

* George K. Lewis, University of Maryland, Institute of Human Virology, USA

M Anthony Moody, Duke University Medical Center, USA

Rogier W. Sanders, Weill Medical College of Cornell University, USA
Neutralizing Antibodies Induced by a Soluble Cleaved HIV Envelope Trimer, BG505 SOSIP.664 gp140

Jens P. Wrammert, Emory University, USA
Interrogating SIV/HIV Specific Plasmablast Responses in Rhesus macaques

Alejandro Balazs, Massachusetts General Hospital, USA

Burton E. Barnett, University of California, San Diego, USA

15:30—17:00
Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endgame
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

NOTE: Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.

16:30—17:00
Coffee Available

17:00—18:45
Cellular and Genetic Therapies for HIV/AIDS (Joint)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Nicole Frahm, Fred Hutchinson Cancer Research Center, USA

* J. Victor Garcia-Martinez, University of North Carolina, USA

Robert F. Siliciano, Johns Hopkins University School of Medicine, USA
Prospects for HIV Eradication

Nicolas Chomont, Vaccine & Gene Therapy Institute of Florida, USA
HIV Persistence during ART: What Can We Learn from CD4 T Cell Homeostasis?

Jerome A. Zack, University of California, Los Angeles, USA
Novel Means for Eliminating Latent HIV Reservoirs

18:45—19:30
Keynote Address (Joint)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Mark M. Davis, Stanford University, USA

19:30—20:30
Social Hour with Lite Bites

20:00—23:00
Entertainment


FRIDAY, MARCH 14

 
Departure


*Session Chair †Speaker invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Bill & Melinda Gates Foundation Gilead Sciences, Inc.

We gratefully acknowledge additional support for this conference from:

Canadian HIV Vaccine Initiative Research & Development Alliance

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13AI110242-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


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