Registered Attendees

Registered Attendees

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Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

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Fairmont Hotel Vancouver Floorplan

Fairmont Hotel Vancouver Floorplan

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NOTES:
This meeting occurs in 2015.
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


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Twitter hashtag for this meeting: #Kstumormet

Integrating Metabolism and Tumor Biology (J1)

joint with the meeting on PI 3-Kinase Signaling Pathways in Disease (J2)

Scientific Organizers: Ralph J. DeBerardinis, Robert T. Abraham and Eyal Gottlieb


January 13—18, 2015

Fairmont Hotel Vancouver, Vancouver, British Columbia, Canada


Sponsored by Astellas Pharma Inc., Bayer HealthCare Pharmaceuticals, Cell Signaling Technology, Inc., ImmunoGen, Inc., Pfizer Inc. and Takeda Pharmaceutical Company


IT’S NOT TOO LATE TO SUBMIT YOUR ABSTRACT. Abstracts received can no longer be considered for oral short talks; poster display opportunities remain open.
Registered attendees of one meeting in a joint pair may participate in sessions of the other, pending space availability.

DEADLINES:
Scholarship Deadline: Sep 24, 2014 [details]
Discounted Abstract Deadline: Sep 24, 2014 [details]
Abstract Deadline: Oct 16, 2014 [details]
Discounted Registration Deadline: Nov 13, 2014 [details]

Submit an Abstract Register Yourself Deadlines and Fees
Deadlines and Fees for 2015-J1 ''Integrating Metabolism and Tumor Biology''
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Rates and Deadlines listed below are for the 2015-J1 "Integrating Metabolism and Tumor Biology" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On September 24, 2014 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After September 24, 2014 until November 13, 2014 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
September 24, 2014 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 13, 2014 845.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After November 13, 2014 995.00 USD
Discounted STUDENT Registration
More details
Before and On November 13, 2014 620.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After November 13, 2014 770.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will    accept no liability for money loss through bank charges, transfers or currency fluctuations.

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About Discounted Abstract Deadline
About Global Health Travel Award Deadline
About Scholarship Deadline
About Abstract Deadline
About Discounted Registration Deadline

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, JANUARY 13

16:00—20:00
Arrival and Registration

18:00—20:00
Mixer


WEDNESDAY, JANUARY 14

07:00—08:00
Breakfast

08:00—09:00
Keynote Address (Joint)
Registered attendees can view abstracts starting on 12/13/2014

Lewis C. Cantley, Weill Cornell Medical College, USA
Phosphoinositide Kinases and Cancer Metabolism

09:00—11:15
Oncogenic Control of Metabolism (Joint)
Registered attendees can view abstracts starting on 12/13/2014

Ronald A. DePinho, University of Texas MD Anderson Cancer Center, USA
KRAS in Cancer Cell Metabolism and Tumor Maintenance

John Blenis, Weill Cornell Medical College, USA
mTOR Control of Glutamine Metabolism

David M. Sabatini, Whitehead Institute for Biomedical Research, USA
mTOR and the Cell Biology of Nutrient Sensing

Short Talk(s) Chosen from Abstracts

09:40—10:00
Coffee Break

11:15—13:00
Poster Setup

13:00—22:00
Poster Viewing

11:15—14:30
On Own for Lunch

14:30—16:30
Workshop 1: Career Development in Cancer Metabolism

16:30—17:00
Coffee Available

17:00—19:00
Metabolic Perturbations that Drive Malignancy
Registered attendees can view abstracts starting on 12/13/2014

Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA
Role of Glycolytic Regulation in Tumor Biology

William G. Kaelin, Jr., Dana-Farber Cancer Institute, USA
2-Hydroxyglutarate Induces a Reversible State of Malignant Transformation

Binhua P. Zhou, University of Kentucky College of Medicine, USA
Metabolic Facilitators of the Epithelial-Mesenchymal Transition

Short Talk Chosen from Abstracts

17:00—19:00
PI3K Effectors
Registered attendees can view abstracts starting on 12/13/2014

NOTE: Proteins that Bind PI3K Lipid Products: Function in Cancer and Immune Disease.

Alex Toker, Beth Israel Deaconess Medical Center, USA
PI 3-Kinase and Akt at the interface of signaling and metabolism

Yoshinori Fukui, Kyushu University, Japan
Critical Roles of DOCK Family Proteins in Migration and Activation of Leukocytes

Sonja Vermeren, University of Edinburgh, UK
PI3K Regulates Integrin-Dependent Processes in the Neutrophil by Signaling through ARAP3

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour with Lite Bites

19:30—22:00
Poster Session 1


THURSDAY, JANUARY 15

07:00—08:00
Breakfast

08:00—11:00
Mitochondrial Metabolism and Cancer
Registered attendees can view abstracts starting on 12/13/2014

Navdeep S. Chandel, Northwestern University, USA
Mitochondrial Metabolism Regulates Cell Proliferation and Epigenetics

Paul Hwang, National Institutes of Health, USA
Role of TP53 in Regulating Mitochondrial Metabolism

Ralph J. DeBerardinis, University of Texas Southwestern Medical Center, USA
Conventional and Unconventional Roles of Mitochondrial Enzymes in Tumor Cell Metabolism

Short Talk(s) Chosen from Abstracts

08:00—11:00
PI3K/Akt/mTOR in Immune Function, Inflammation
Registered attendees can view abstracts starting on 12/13/2014

Phillip T. Hawkins, Babraham Institute, UK
PI3K Signaling in Neutrophils

Klaus Okkenhaug, Babraham Institute, UK
PI3K in Immunity, Infection and Cancer

David A. Fruman, University of California, Irvine, USA
Insights Concerning the Selective Action of Rapamycin in Lymphocytes

Robert C. Rickert, Sanford-Burnham Medical Research Institute, USA
The PI3K Pathway in B Cell Metabolism

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

11:00—13:00
Poster Setup

13:00—22:00
Poster Viewing

11:00—14:30
On Own for Lunch

14:30—16:30
Workshop 2: Novel Targets and Pathways

Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

17:00—19:15
Model Organisms as Tools to Understand Metabolism, Growth and Cancer
Registered attendees can view abstracts starting on 12/13/2014

Benjamin Tu, University of Texas Southwestern Medical Center, USA
Yeast Metabolic Cycles and the Regulation of Cell Growth

Valeria Fantin, Pfizer, USA
Talk Title to be Announced

Alex Gould, MRC National Institute for Medical Research, UK
Protecting Neural Stem Cells from Starvation and Hypoxia in Drosophila

Leonard I. Zon, HHMI/Children's Hospital Boston, USA
The Role of Nucleotide Deficiency in the Transcriptional Regulation of Neural Crest Differentiation and Melanoma

Short Talk Chosen from Abstracts

17:00—19:00
PI3K in Cancer
Registered attendees can view abstracts starting on 12/13/2014

Lori Friedman, Genentech, Inc., USA
Sensitivity and Resistance to PI3K Pathway Inhibitors

Vuk Stambolic, Ontario Cancer Institute/University Health Network, Canada
Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

Jean J. Zhao, Dana-Farber Cancer Institute, USA
Targeting PI3K Isoforms in Cancer: Mechanistic and Therapeutic Insights from Genetic Mouse Models

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour with Lite Bites

19:30—22:00
Poster Session 2


FRIDAY, JANUARY 16

07:00—08:00
Breakfast

07:30—08:00
Poster Setup

08:00—17:00
Poster Viewing

08:00—11:00
Targeting Cancer Cell Metabolism
Registered attendees can view abstracts starting on 12/13/2014

Robert T. Abraham, Pfizer Worldwide Research and Development, USA
Glutamine Deprivation Stimulates a Stress-Response Network in Cancer Cells

Katharine Yen, Agios Pharmaceuticals, USA
Targeting Mutant IDH in Cancer

Reuben J. Shaw, The Salk Institute, USA
The LKB1 - AMPK Tumor Suppressor Pathway: Metabolic Reprogramming and Therapeutic Targeting

Short Talk(s) Chosen from Abstracts

08:00—11:00
PI3K/Akt/mTOR Clinical Translational - Oncology
Registered attendees can view abstracts starting on 12/13/2014

Speaker to be Announced

José Baselga, Memorial Sloan-Kettering Cancer Center, USA
PI3k and mTOR Inhibitors in Breast Cancer

Mika Derynck, Genentech, Inc., USA
PI3K Inhibitor Drug Development in Clinical Cancer Trials

Speaker to be Announced

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

11:00—12:00
Lunch

12:00—14:30
Poster Session 3

14:30—16:30
Workshop 3: Strategies for Discovery of Metabolism: Targeted Drugs

Short Talks Chosen from Abstracts

14:30—16:30
Workshop

Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

17:00—19:15
Metabolite Control of Gene Expression and Protein Function
Registered attendees can view abstracts starting on 12/13/2014

Craig B. Thompson, Memorial Sloan-Kettering Cancer Center, USA
Metabolic Control of Epigenetics in Cancer

Poul H. B. Sorensen, University of British Columbia, Canada
The eEF2K Translation Factor and Metabolic Reprogramming in Tumor Cells

Eric M. Verdin, University of California, San Francisco, USA
Mitochondrial Protein Acylation and the Sirtuins

Marcia C. Haigis, Harvard Medical School, USA
Post-Translational Modifications and Control of Mitochondrial Metabolism

Short Talk Chosen from Abstracts

17:00—19:00
PI3K/Akt/mTOR Clinical Translational - Inflammation
Registered attendees can view abstracts starting on 12/13/2014

Augustin Amour, GlaxoSmithKline, UK
The Development of a Promising Inhaled PI3Kdelta Inhibitor for the Treatment of Respiratory Indications

Alison Mary Condliffe, University of Cambridge, UK
Activated PI3 Kinase Delta Syndrome (APDS): A Novel Combined Immunodeficiency Disorder

David G. Winkler†, Infinity Pharmaceuticals, Inc., USA
Talk Title to be Announced

Short Talk Chosen from Abstracts


SATURDAY, JANUARY 17

07:00—08:00
Breakfast

08:00—11:00
Metabolic Consequences of Cell Stress
Registered attendees can view abstracts starting on 12/13/2014

Eileen P. White, Rutgers University, USA
Autophagy and Mitochondrial Metabolism in Cancer

Eyal Gottlieb, Cancer Research UK, Beatson Institute, UK
Pyruvate Carboxylation is Required for Growth of Succinate Dehydrogenase-Deficient Cells

Karen H. Vousden, Beatson Institute for Cancer Research, UK
A Role for p53 in the Regulation of Metabolism

Kun-Liang Guan, University of California, San Diego, USA
The Hippo-YAP Pathway in Organ Size Control and Tumorigenesis

Short Talk(s) Chosen from Abstracts

08:00—11:00
Class II/III PI3K, Trafficking
Registered attendees can view abstracts starting on 12/13/2014

NOTE: Linking Vps34 Regulation of Trafficking with Other Sessions - Autophagy, Metabolism.

Bart Vanhaesebroeck, UCL Cancer Institute, UK
New Physiological Roles of PI3K Isoforms

Volker Haucke, Leibniz Institut fuer Molekulare Pharmakologie, Germany
Spatiotemporal Control of Endocytosis and Endosomal Membrane Traffic by PI 3-Phosphates

Sharon A. Tooze, London Research Institute, UK
The Role of PI3P and WIPI2 in Autophagy

Gilbert Di Paolo, Columbia University Medical Center, USA
Dysregulation of Class III PI3K/Vps34 Signaling in Neurons Recapitulates Key Features of Alzheimer's Disease

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

11:00—14:30
On Own for Lunch

14:30—16:30
Workshop: Autophagy (Joint)

Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

17:00—18:45
Influence of the Metabolic Environment on Cancer Development and Tumor Growth
Registered attendees can view abstracts starting on 12/13/2014

Dafna Bar-Sagi, New York University School of Medicine, USA
RAS-Mediated Uptake of Nutrients from the Microenvironment

Philipp E. Scherer, University of Texas Southwestern Medical Center, USA
Adipokines and Tumor Progression

Robert J. Gillies, H. Lee Moffitt Cancer Center and Research Institute, USA
Buffer Therapy

17:00—18:45
PI3K Structure and Regulation
Registered attendees can view abstracts starting on 12/13/2014

NOTE: Insights into Structure of PI3K Enzymes, Inhibitor Binding, and Other Modes of Regulation.

Roger L. Williams, Medical Research Council, UK
Structural Insights into Vps34 Regulation

Leon O. Murphy, Novartis, USA
Generation of Selective VPS34 Inhibitors to Probe the Autophagy Pathway

Jonathan M. Backer, Albert Einstein College of Medicine, USA
The Complex Functions of p110beta: A Critical Integrator of Signals from GPCRs and Small GTPases

18:45—19:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/13/2014

18:45—19:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/13/2014

19:15—20:15
Social Hour with Lite Bites

20:00—23:00
Entertainment


SUNDAY, JANUARY 18

 
Departure


*Session Chair †Speaker invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Astellas Pharma Inc. Bayer HealthCare Pharmaceuticals
Cell Signaling Technology, Inc. ImmunoGen, Inc.
Pfizer Inc. Takeda Pharmaceutical Company Limited

We gratefully acknowledge additional support for this conference from:

CEDARLANE Seahorse Bioscience, Inc.

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



GlaxoSmithKline


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Amanda Deem, Assistant Director of Development, Email: AmandaD@keystonesymposia.org,
Phone:+1 970-262-2668

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676