Fairmont Banff Springs Floorplan

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This meeting took place in 2016


Here are the related meetings in 2017:
Integrating Metabolism and Immunity (E4)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Immunometabolism in Immune Function and Inflammatory Disease (Q8)


Organizer(s) Jeffrey C. Rathmell, Jonathan D. Powell and Amira Klip
February 21—25, 2016
Fairmont Banff Springs • Banff, Alberta Canada
Discounted Abstract Deadline: Oct 22, 2015
Abstract Deadline: Nov 23, 2015
Scholarship Deadline: Oct 22, 2015
Discounted Registration Deadline: Dec 21, 2015

Sponsored by AbbVie Inc., Abide Therapeutics Inc., Astellas Pharma Inc. and Boehringer Ingelheim Pharmaceuticals, Inc.


Summary of Meeting:
It is now evident that an integral component of immune regulation is through the metabolic pathways necessary to support energetically demanding protective or pathogenic responses. Deciphering these links in the emerging field of immunometabolism is critical to understanding basic immune function. Activation, differentiation and function of M1 & M2 macrophages, Th1, Th2, Th17 & T regulatory T cells as well as effector and memory CD8+ T cells are all inexorably linked to pathways that regulate cellular metabolism. Likewise, systemic metabolism and metabolic diseases are very much influenced by immunity, as the metabolic syndrome in obesity is mediated in part by dysregulated immune cells similar to inflammatory and autoimmune disease states. This meeting addresses how immune cells and functions rely upon and are controlled by specific metabolic pathways and nutrient availability and will bridge systemic and cellular metabolic regulation of immune function. Metabolic reprogramming in the activation of adaptive and innate immune cells and the regulation and role of specific metabolic programs in distinct lymphocyte or macrophage subsets will be addressed. The conference will also present new findings on signaling pathways and the influence of immune cell metabolism on anti-tumor immunity, autoimmunity and metabolic diseases. It is anticipated this meeting will be of broad interest to the immunology and metabolic communities. The focus of this meeting on how factors that influence immune cell metabolism impact a variety of inflammatory disorders will provide new fundamental insight into normal immune function as well as opportunities to treat immunological and metabolic diseases.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, February 21 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 25 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 26 in order to fully experience the meeting.

SUNDAY, FEBRUARY 21

16:00—20:00
Arrival and Registration

Van Horne Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Van Horne Foyer

MONDAY, FEBRUARY 22

07:00—08:00
Breakfast

Mezzanine 2
08:00—09:30
Welcome and Keynote Session (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Chi Van Dang, University of Pennsylvania, USA

* Jeffrey C. Rathmell, Vanderbilt University, USA

Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland
Metabolic Reprogramming as a Driver of Macrophage-Mediated Inflammation

Joan S. Brugge, Harvard Medical School, USA
Computational Analysis of Genetic and Phenotypic Contributions to Metabolic Gene Expression in Cancer

09:30—09:50
Coffee Break

Van Horne Foyer
09:50—12:00
Metabolic Basis for Cell Proliferation and Regulation (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Chi Van Dang, University of Pennsylvania, USA

* Jeffrey C. Rathmell, Vanderbilt University, USA

Michael Karin, University of California, San Diego, USA
Signaling in Inflammatory Pathways

Tak W. Mak, Campbell Family Institute for Breast Cancer, Canada
Metabolic Adaptation in Cancer Cells: Exploiting Cancer Metabolic Vulnerabilities

Lewis C. Cantley, Weill Cornell Medicine, USA
PI3K and Cancer Metabolism

Mark A. Febbraio, Garvan Institute of Medical Research, Australia
Short Talk: The Chameleon Role TLR4 in Lipid-Induced Macrophage Inflammation

Thomas G. Graeber, University of California, Los Angeles, USA
Short Talk: Recurrent Patterns of DNA Copy Number Alterations in Tumors Reflect Metabolic Selection Pressures

12:00—13:00
Poster Setup

Mezzanine 2
13:00—22:00
Poster Viewing

Mezzanine 2
12:00—14:30
On Own for Lunch

14:30—16:30
Workshop 1: Metabolism of Lymphocytes

Van Horne C
* Christoph Hess, University Hospital Basel, Switzerland

* Laurence Morel, University of Florida, USA

Brian M. Iritani, University of Washington, USA
Metabolic Control of Peripheral B Lymphocyte Development and Homeostasis by the AMPK-Interacting Protein Fnip1

Linda V. Sinclair, University of Dundee, Scotland
Antigen Receptor Control of Methionine Metabolism

Michael Buck, Max Planck Institute of Immunobiology and Epigenetics, Germany
Promoting CD8 T Cell Memory through Mitochondrial Dynamics

Eric H. Ma, McGill University, Canada
Investigating the Role of Serine Metabolism for T Cell Proliferation and Function

Lelisa F. Gemta, University of Virginia, USA
Metabolism as a Functional Constraint of Tumor Infiltrating CD8+ T Cells

David C. Clever, National Institutes of Health, USA
T Cell Oxygen Sensing Suppresses Pulmonary Effector Responses and Licenses Lung Tumor Metastasis

Nancie J. MacIver, Duke University Medical Center, USA
Leptin Directly Promotes T Cell Glycolytic Metabolism to Drive Th17 Differentiation

Dan Wu, University of British Columbia, Canada
Adipocytes Promote Regulatory T Cell Metabolism and Function

14:30—16:30
Workshop 1: New Concepts

Van Horne A/B
* Joshua D. Rabinowitz, Princeton University, USA

Michael Aregger, University of Toronto, Canada
High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

Thales Panos Papagiannakopoulos, New York University School of Medicine, USA
Dissecting the Role of Aberrant Oxidative Homeostasis in Lung Cancer

Kivanc Birsoy, Rockefeller University, USA
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

Lucas B. Sullivan, Massachusetts Institute of Technology, USA
Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

Kevin Marks, Agios Pharmaceuticals, USA
Metabolite Accumulation in MTAP-Deficient Cancers Creates Targetable Collateral Vulnerabilities

Zachary Bacigalupa, Drexel University, USA
Role of OGT and O-GlcNAcylation in Glioblastoma Lipid Metabolism and Growth

Brooke M. Emerling, Sanford Burnham Prebys Medical Discovery Institute, USA
Phosphatidylinositol-5-Phosphate 4-Kinases Are Essential for Survival during Metabolic Stress

Sun Mi Hong, Pohang University of Science and Technology, POSTECH, South Korea
NAMPT Regulates Metabolic Stress in Cancer Progression by Maintaining NADPH Levels

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Metabolic Regulation of Macrophage Function
Meeting has ended...abstracts no longer viewable online.
The goals of this plenary session are to discuss the role of metabolic reprogramming and altered metabolism in macrophage activation and inflammatory function.

Van Horne C
* Mark A. Febbraio, Garvan Institute of Medical Research, Australia

Ajay Chawla, University of California, San Francisco, USA
Innate Control of Adipose Tissue Metabolism

Anthony W. Ferrante, Columbia University, USA
Metabolic Diseases and Macrophage Populations

Amira Klip, Hospital for Sick Children, Canada
Crosstalk between Muscle and Macrophages

Oscar R. Colegio, Yale University, USA
Short Talk: Tumor-Derived Lactic Acid Functionally Polarizes Tumor-Associated Macrophages

17:00—19:15
Fundamentals of Cell Metabolism: Metabolic Wiring and in vivo Studies
Meeting has ended...abstracts no longer viewable online.

Van Horne A/B
* Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA

Joshua D. Rabinowitz, Princeton University, USA
Quantitative Analysis of Metabolic Activity.

Christian Metallo, University of California, San Diego, USA
Understanding and Exploiting Metabolic Flexibility in Human Cells

Ralph J. DeBerardinis, University of Texas Southwestern Medical Center, USA
Understanding Metabolic Heterogeneity in Human Cancer Cells and Tumors

Teresa W. M. Fan, University of Kentucky Markey Cancer Center, USA
Exploring Lung Cancer Metabolome: In vivo and ex vivo

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Mezzanine 2
19:30—22:00
Poster Session 1

Mezzanine 2

TUESDAY, FEBRUARY 23

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:15
Effector and Regulatory T Cell Metabolism and Function
Meeting has ended...abstracts no longer viewable online.
The goals of this session are to discuss T cell subsets and how metabolic signaling and environment affect subset establishment and selection.

Van Horne C
* Richard M. Siegel, NIAMS, National Institutes of Health, USA

Jeffrey C. Rathmell, Vanderbilt University, USA
Glucose Uptake and Fueling T Cell Immunity

Hongbo Chi, St. Jude Children's Research Hospital, USA
Interplay between Immune Signaling and Cell Metabolism in Effector and Treg Cells

Steven J. Bensinger, University of California, Los Angeles, USA
Towards Understanding the Importance of Sterol Metabolism in Host Defense

Laurence A. Turka, Massachusetts General Hospital, USA
Regulatory T Cell Metabolism - Does Form Affect Function?

Sam Weinberg, Northwestern University, USA
Short Talk: Mitochondrial Complex III is Required Regulatory T Cell Function

Nicholas R. J. Gascoigne, National University of Singapore, Singapore
Short Talk: T-Cell-Specific Signaling Molecule Themis in T Cell Metabolism, Obesity, and Type 2 Diabetes

08:00—11:15
Metabolic Adaptation
Meeting has ended...abstracts no longer viewable online.
Transcriptional Regulation of Metabolism

Van Horne A/B
* Ralph J. DeBerardinis, University of Texas Southwestern Medical Center, USA

M. Celeste Simon, HHMI/University of Pennsylvania, USA
Hypoxia, Metabolism and Renal Cancer

Peter F. Carmeliet, University of Leuven, VIB, Belgium
Angiogenesis Revisited: Role and (Therapeutic) Implications of Endothelial Metabolism

Reuben J. Shaw, The Salk Institute for Biological Studies, USA
The LKB1 – AMPK Pathway: Metabolic Rewiring and Therapeutic Targeting

Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA
Insights from Metabolism Studies in Mouse Cancer Models

Sarah-Maria Fendt, University of Leuven, Belgium
Short Talk: Breast Cancer Cells Depend on ATP Production from Proline Catabolism during Metastatic Colonization

Guido T. Bommer, Universite Catholique de Louvain, Belgium
Short Talk: Identification of a Multi-Functional Enzyme Protecting Glycolysis and the Pentose Phosphate Pathway from Metabolic Side-Products

09:20—09:40
Coffee Break

Van Horne Foyer
11:15—13:00
Poster Setup

Mezzanine 2
13:00—22:00
Poster Viewing

Mezzanine 2
11:15—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
The AMPK/mTOR Axis in Metabolism, Inflammation and Immunity
Meeting has ended...abstracts no longer viewable online.
The goal of this plenary session is to discuss the role of signaling through the mTOR pathway in immune cell metabolism and function.

Van Horne C
* David K. Finlay, Trinity Biomedical Sciences Institute, Ireland

Russell G. Jones, McGill University, Canada
LKB1: Links between Inflammation and Tumor Development

Jonathan D. Powell, Johns Hopkins University School of Medicine, USA
Targeting mTOR and Metabolism as a Means of Regulating T Cell Activation, Differentiation and Function

Tiffany Horng, Harvard School of Public Health, USA
Metabolic Calibration of Macrophage Activation

Mark R. Boothby, Vanderbilt University Medical Center, USA
Short Talk: Hypoxia Suppresses Amino Acid Uptake and mTORC1 Activity, Causing Altered Class Switch Biases and Attenuation of Antibody Responses

17:00—19:15
Oncogenes and Tumor Suppressors and Metabolism
Meeting has ended...abstracts no longer viewable online.
Transcriptional Regulation of Metabolism

Van Horne A/B
* Navdeep S. Chandel, Northwestern University, USA

Robert N. Eisenman, Fred Hutchinson Cancer Research Center, USA
Transcriptional Regulation by the MAX-Like Protein MLX is Required for Increased Metabolic Demand Associated with Tumorigenesis and Spermatogenesis

Mariia Yuneva, Francis Crick Institute, UK
Metabolic Lessons Learned from in vivo Tumor Models

Karen H. Vousden, Beatson Institute for Cancer Research, UK
One Carbon Metabolism and Cancer

Don Ayer, University of Utah, USA
Short Talk: c-Myc and MondoA Couple Nutrient Utilization and Availability in Tumorigenesis

Zhimin Lu, University of Texas MD Anderson Cancer Center, USA
Short Talk: The Unique Features of Liver Tumor Cell Metabolism

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Mezzanine 2
19:30—22:00
Poster Session 2

Mezzanine 2

WEDNESDAY, FEBRUARY 24

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:15
Metabolism of Inflammation and Innate Immune Responses
Meeting has ended...abstracts no longer viewable online.
The goal of this plenary session is to discuss how metabolic pathways link inflammation and innate immune cells.

Van Horne C
* Tiffany Horng, Harvard School of Public Health, USA

Erika L. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany
Metabolic Pathways in Effector and Memory T Cells

Helen C. Su, NIAID, National Institutes of Health, USA
Proteolysis and Metabolism in Human Immunodeficiency

Melinda A. Beck, University of North Carolina, USA
Viral Infection and Metabolism

Richard M. Siegel, NIAMS, National Institutes of Health, USA
Fueling the Fire: Mitochondria and Metabolism in Autoinflammatory Disease

David K. Finlay, Trinity Biomedical Sciences Institute, Ireland
Short Talk: SREBP Sustains Elevated Glycolysis and Effector Functions in Cytokine Activated Natural Killer Cells

Claudio Mauro, Queen Mary University of London, UK

08:00—11:15
Signaling and Metabolic Enzymes
Meeting has ended...abstracts no longer viewable online.
Post-Transcriptional Regulation of Metabolism

Van Horne A/B
* Tak W. Mak, Campbell Family Institute for Breast Cancer, Canada

Nika N. Danial, Dana-Farber Cancer Institute, USA
Metabolic Heterogeneity in Molecular Subtypes of Diffuse Large B Cell Lymphoma

David M. Sabatini, Whitehead Institute for Biomedical Research, USA
Nutrient Sensing and Tumor Metabolism

Brendan D. Manning, Harvard School of Public Health, USA
Linking Growth Signaling to Anabolic Metabolism

Kathryn E. Wellen, University of Pennsylvania, USA
Tumor Metabolism and the Epigenome

Ahmad A. Cluntun, Cornell University, USA
Short Talk: The Rate of Glycolysis Quantitatively Mediates Specific Histone Acetylation Sites

Roberto Zoncu, University of California, Berkeley, USA
Short Talk: Convergence of Multiple Nutrient Signals Regulates mTORC1 at the Lysosome

09:20—09:40
Coffee Break

Van Horne Foyer
11:15—13:00
Poster Setup

Mezzanine 2
13:00—22:00
Poster Viewing

Mezzanine 2
11:15—14:30
On Own for Lunch

14:30—16:30
Workshop 2: The Metabolic Regulation of Innate Immunity

Van Horne C
* Janelle S. Ayres, The Salk Institute for Biological Studies, USA

* Steven J. Bensinger, University of California, Los Angeles, USA

Maroof Hasan, Novartis Institutes for BioMedical Research, Switzerland
Immuno-Metabolic Dysregulation in Aicardi-Goutieres Syndrome and Related Autoimmune Diseases

Jonathan M. Coquet, Karolinska Institute, Sweden
The Role of PPAR-gamma in Type 2 Immunity

Emily Goldberg, Yale University, USA
Beta-Hydroxybutyrate, an Alternate Metabolic Fuel, Inhibits Neutrophilic Inflammation by Blocking NLRP3 Inflammasome Activation

Mahesh Raundhal, University of Pittsburgh, USA
PPARg Regulates Mitochondrial Respiration in CD11c+ Cells to Ensure Immune Tolerance in the Airways

Shuang Zhang, Northwestern University, USA
Apoptotic Cell Metabolites during Efferocytosis Fuel Mitochondrial-Directed Inflammatory Reprogramming in Macrophages

Samuel L. Collins, Johns Hopkins University, USA
mTORC2 Integrates Cues from the Environment to Program Macrophage Differentiation and Regulate Systemic Immune and Thermogenic Responses

Martin Pelletier, Centre de Recherche du CHU de Québec - Université Laval, Canada
Metabolic Adaptation of Polymorphonuclear Neutrophils Activated with Pro-Inflammatory Cytokines

Jose C. Alves Filho, University of São Paulo, Brazil
Fructose 1,6-bisphosphate, a High-Energy Intermediate of Glycolysis, Reprograms Macrophages Limiting their Activated State

14:30—16:30
Workshop 2: Therapeutics

Van Horne A/B
* Katharine Yen, Agios Pharmaceuticals, USA

Mark G. Manfredi, Raze Therapeutics, USA
One Carbon Metabolism in Cancer

Maria Bueno, Centro Nacional de Investigaciones Oncológicas, Spain
FASN: A Metabolic Strategy for Breast Cancer Prevention

Douglas I. Buckley, 3V Biosciences, Inc., USA
Sebum Analysis from Dose Escalation and Expansion Phases of the FASN Inhibitor TVB-2640 Phase 1 Trial, A Non-Invasive Biomarker of Target Engagement

Sven Christian, Bayer, Germany
3D High-Content Screening for the Identification of Compounds that Target Cells in the Core of Tumor Spheroids

Thomas Ashton, Gray Institute for Radiation Oncology and Biology, UK
Increasing Radiosensitivity by Alleviating Tumour Hypoxia: A Drug Screen Reveals Atovaquone as a Clinical Candidate

Kathy Ann Gelato, Bayer Healthcare AG, Germany
OXPHOS and Epigenetics: Paths to BET Inhibitor Sensitivity in Melanoma

Pankaj Kumar Singh, University of Nebraska Medical Center, USA
Metabolic Flux into Nucleotide Biosynthesis Pathway Regulates Chemotherapy Responsiveness in Pancreatic Cancer

Jing Chen, Winship Cancer Institute, Emory University, USA
Inhibition of Human Copper Trafficking by Small Molecule Significantly Attenuates Cancer Cell Proliferation

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Cell-Cell Communication in Immunometabolism
Meeting has ended...abstracts no longer viewable online.
The goal of this session is to discuss how systemic changes in metabolism influence metabolism and interactions of immune cells with metabolic tissues.

Van Horne C
* Amira Klip, Hospital for Sick Children, Canada

Bente Klarlund Pedersen, Rigshospitalet, Denmark
Exercise-Induced Immunometabolism - Focus on Myokines

Benedicte Chazaud, Université Claude Bernard Lyon, France
Macrophages Differentially Regulate Myogenesis and Fibrogenesis in Acute Muscle Regeneration and Chronic Muscle Disease

Vishwa Deep Dixit, Yale University, USA
Immunometabolic Inhibitors of Inflammasome and Metchnikoff’s Prediction of Longevity

Janelle S. Ayres, The Salk Institute for Biological Studies, USA
Short Talk: Muscle Wasting Protection Mediated by Microbiome E. coli Involves Inflammasome and IGF-1 Signaling

17:00—19:15
PI3K/AMPK
Meeting has ended...abstracts no longer viewable online.
Post-Transcriptional Regulation of Metabolism

Van Horne A/B
* Lewis C. Cantley, Weill Cornell Medicine, USA

Navdeep S. Chandel, Northwestern University, USA
Mitochondrial Function in Normal and Tumor Metabolism

Nissim Hay, University of Illinois at Chicago, USA
Akt, Metabolism and Cancer Therapy: Surprising Lessons from Akt KO Mice

Heather Christofk, University of California, Los Angeles, USA
Use of Viruses to Study Cancer Metabolism

Boyi Gan, MD Anderson Cancer Center, USA
Short Talk: Regulation of AMPK Activation and Cancer Metabolism by Long Noncoding RNAs

Zachary Schug, Beatson Institute for Cancer Research, UK
Short Talk: MYC Expression in Human Mammary Epithelial Cells Enhances Metabolic Plasticity

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Mezzanine 2
19:30—22:00
Poster Session 3

Mezzanine 2

THURSDAY, FEBRUARY 25

07:00—08:00
Breakfast

Mezzanine 2
08:00—11:15
Metabolic Reprogramming in Lymphocyte Cell Activation and Memory
Meeting has ended...abstracts no longer viewable online.
The goal of this session is to discuss mechanisms that regulate metabolic changes in T cell activation and in generation of T cell memory.

Van Horne C
* Jonathan D. Powell, Johns Hopkins University School of Medicine, USA

Edward J. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany
Metabolism of Dendritic Cell Activation

Christoph Hess, University Hospital Basel, Switzerland
Metabolic Reprogramming in Memory T Cells and Immunodeficiency

Gary Glick, University of Michigan, USA
Mitochondrial Function in Immunity; Mechanisms and Therapeutic Potential

Douglas R. Green, St. Jude Children's Research Hospital, USA
Born Different: Metabolic Maintenance of Asymmetric T Cell Division

Greg M. Delgoffe, University of Pittsburgh, USA
Short Talk: Metabolic Insufficiency Underlies Intratumoral Cytotoxic T Cell Dysfunction

Laurence Morel, University of Florida, USA
Short Talk: Targeting CD4+ T Cell Metabolism in Lupus

08:00—11:00
Isocitrate Dehydrogenase
Meeting has ended...abstracts no longer viewable online.
Therapeutic Implications

Van Horne A/B
* Karen H. Vousden, Beatson Institute for Cancer Research, UK

Katharine Yen, Agios Pharmaceuticals, USA
New Developments in Targeting IDH Mutations

Sunil Sudarshan, University of Alabama, Birmingham, USA
Short Talk: The L-2HG/L2HGDH Axis in Kidney Cancer

Wilhelm Palm, Memorial Sloan-Kettering Cancer Center, USA
Beyond Glucose and Glutamine: Some Cancer Cells Utilize Extracellular Macromolecules to Fuel Cell Growth

Nabeel Bardeesy, Massachusetts General Hospital, USA
Altered Metabolism in Pancreatic Cancer Models

Alexander H. Stegh, Northwestern University, USA
Short Talk: IDH1 Promotes Tumor Growth and Resistance to Targeted Therapies in the Absence of Mutation

Kate Elizabeth Rose Hollinshead, University of Birmingham, UK
Short Talk: IDH1 Mutated Cells Demonstrate Pseudohypoxic Proline Metabolism

09:20—09:40
Coffee Break

Van Horne Foyer
11:15—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Van Horne Foyer
17:00—19:00
Tumor Immunology and Metabolic Immunotherapy
Meeting has ended...abstracts no longer viewable online.
The goal of this session is to discuss the role of the tumor microenvironment in control of anti-tumor immunity.

Van Horne C
* Laurence A. Turka, Massachusetts General Hospital, USA

David H. Munn, Georgia Regents University, USA
IDO, PTEN and mTOR / Akt Signaling in Tregs

Madhusudhanan Sukumar, NCI, National Institutes of Health, USA
Metabolic Properties of Highly Effective T Cells

Susan M. Kaech, Yale University School of Medicine, USA
Fattening Up T Cell Memory

Bertram Bengsch, University of Pennsylvania, USA
Short Talk: Early Onset and Persistence of Metabolic Alterations in Exhausted T-Cells is Controlled by PD-1

17:00—19:15
Targeting Metabolism
Meeting has ended...abstracts no longer viewable online.
Therapeutic Implications

Van Horne A/B
* Robert N. Eisenman, Fred Hutchinson Cancer Research Center, USA

Chi Van Dang, University of Pennsylvania, USA
A Time for MYC, Metabolism, and Therapy

Susan Demo, Calithera Biosciences, USA
Targeting Amino Acid Metabolism for Cancer Treatment

Michael Pollak, Jewish General Hospital, Canada
Targeting Cancer Metabolism with Metformin and Other Biguanides: From Bench to Bedside and Back

Alec Kimmelman, NYU Langone Medical Center, USA
Identifying Metabolic Dependencies in Pancreatic Cancer

19:00—19:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)

Van Horne C
19:15—19:30
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)

Van Horne A/B
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Mezzanine 2
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Mezzanine 2

FRIDAY, FEBRUARY 26

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

AbbVie Inc. Abide Therapeutics Inc.
Astellas Pharma Inc. Boehringer Ingelheim Pharmaceuticals, Inc.

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Adipogen International

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13AI122337-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Novartis Institutes for BioMedical Research


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


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If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676