Big Sky Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

NOTES:
This meeting occurs in 2017.
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


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Twitter hashtag for this meeting: #KStme

Cell Plasticity within the Tumor Microenvironment (A1)

Scientific Organizers: Sergei Grivennikov, Florian R. Greten and Mikala Egeblad


January 8—12, 2017

Big Sky Resort, Big Sky, Montana, USA


Sponsored by Journal of Molecular Cell Biology (JMCB) and Roche


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
Scholarship Deadline: Sep 19, 2016 [details]
Discounted Abstract Deadline: Sep 19, 2016 [details]
Abstract Deadline: Oct 6, 2016 [details]
Discounted Registration Deadline: Nov 8, 2016 [details]

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2017-A1 "Cell Plasticity within the Tumor Microenvironment" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On September 19, 2016 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After September 19, 2016 until December 1, 2016 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
September 19, 2016 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 8, 2016 795.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After November 8, 2016 945.00 USD
Discounted STUDENT Registration
More details
Before and On November 8, 2016 570.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After November 8, 2016 720.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: September 19, 2016


Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is October 6, 2016)

Global Health Travel Award Deadline:


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: September 19, 2016


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: October 6, 2016


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is September 19, 2016)

Discounted Registration Deadline: November 8, 2016


Registration Fee: 795.00 USD* (includes 150.00 USD discount)
Student Registration Fee: 570.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 945.00 USD*
Student Registration Fee: 720.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, January 8 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 12 with a closing plenary session and keynote address from 17:00 to 19:15, followed by a social hour and entertainment. We recommend return travel on Friday, January 13 in order to fully experience the meeting.

SUNDAY, JANUARY 8

16:00—20:00
Arrival and Registration

Lower Atrium
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Jefferson

MONDAY, JANUARY 9

07:00—08:00
Breakfast

Gallatin
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Sergei Grivennikov, Fox Chase Cancer Center, USA

* Florian R. Greten, Institute for Tumor Biology and Experimental Therapy, Germany

* Mikala Egeblad, Cold Spring Harbor Laboratory, USA

Michael Karin, University of California, San Diego, USA
Tumor-Elicited Inflammation and the Initiation of Colorectal Cancer

09:00—11:45
Plasticity of Epithelial, Cancer and Stem Cells
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Cédric Blanpain, Universite Libre de Bruxelles, Belgium

* Shelly Peyton, University of Massachusetts, USA

Florian R. Greten, Institute for Tumor Biology and Experimental Therapy, Germany
Inflammatory Signaling in Intestinal Stem Cell Plasticity

John Cassidy, University of Cambridge, UK
Short Talk: The Development of Tamoxifen Resistance is Linked to Oct4 Driven Transcriptional Plasticity

Coffee Break

Andrew J. Ewald, Johns Hopkins University School of Medicine, USA
Phenotypic Plasticity during Cell Invasion and Metastasis

Kristiaan Lenos, Amsterdam Medical Center, Netherlands
Short Talk: Spatiotemporal Regulation of Stem Cell Function in Colon Cancer

Frederic J. de Sauvage, Genentech, Inc., USA
Targeting Intestinal Stem Cells in Cancer

Brian Bierie, Whitehead Institute for Biomedical Research, USA
Poster Teaser: Integrin-Beta4 Identifies Cancer Stem Cell-Enriched Populations of Partially-Mesenchymal Carcinoma Cells

Jessica L. Christenson, University of Colorado, USA
Poster Teaser: The Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression: Tumor-Intrinsic and Tumor-Extrinsic Mechanisms

Ryan Carpenter, University of Massachusetts, Amherst, USA
Poster Teaser: Capturing Microenvironmental Regulation of Metastatic Dormancy and Recurrence

Sara E. Berkey, University of Pittsburgh, USA
Poster Teaser: The IL17+Foxp3+ and exTh17 Foxp3+ Plastic T Cells Comprise Novel Immunosuppressive Regulatory T Cell Subsets in Tumors

Oxana Dmitrieva, Fox Chase Cancer Center, USA
Poster Teaser: The Role of IL-1R-Signaling in Tumor Elicited Inflammation and Colon Cancer

11:45—14:30
On Own for Lunch

11:45—13:00
Poster Setup

Gallatin
13:00—22:00
Poster Viewing

Gallatin
14:30—16:30
Workshop 1: Plasticity and the Cancer Stem Cell Niche

Jefferson/Madison
* Diana Leigh Avery, University of Pennsylvania School of Medicine, USA
Matrix Mechanics and Composition Dictate Stromal Cell Differentiation in Lung Tumorigenesis

Ikbale El Ayachi, University of Tennessee Health Science Center, USA
The Absence of Wnt10b Expression Inhibits Tumor Initiation and Metastasis Modulating Stroma-Tumor Microenvironment Homeostasis

* Loukia Georgiou Karacosta, Stanford University, USA
Identifying Dynamic EMT Transition States in Lung Cancer Using Single Cell Multidimensional Analysis

Hazel Quinn, Max Delbruck Centre, Germany
Genetically Interfering with the Tumor Microenvironment via Shh in Wnt-Met driven Mouse Triple Negative Breast Cancer

Michael Buchert, Olivia Newton-John Cancer Research Institute, Australia
Insights into the Role of DCLK1 as a Novel Driver of Gastric Cancer

Toni Celia-Terrassa, Princeton University, USA
Pathways Regulating the Evasion of Normal and Cancer Stem Cells from Interferon-Imposed Constraint

Dejan Maglic, Boston Children's Hospital, USA
The Hedgehog and Hippo Pathways Cooperate in BCC Initiation and Progression

Mokarram Hossain, University of Calgary, Canada
Liver Metastases of C26 Colon Carcinoma Cells Recruit GATA6+ Large Peritoneal Macrophages

16:30—17:00
Coffee Available

Lower Atrium
17:00—19:00
Plasticity and (Cancer) Stem Cell Niche
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Florian R. Greten, Institute for Tumor Biology and Experimental Therapy, Germany

* Louis Vermeulen, CEMM, Netherlands

Jing Yang, University of California, San Diego, USA
Epithelial-Mesenchymal Plasticity in Carcinoma Metastasis

Cédric Blanpain, Universite Libre de Bruxelles, Belgium
Skin Tumor Stemness and Progression

Ekrem Emrah Er, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Pericytic Spreading of Disseminated Cancer Cells Initiate Multi-Organ Metastasis

Andreas Trumpp, German Cancer Research Center, Germany
Stratification and Resistance Mechanisms in Pancreatic Cancer

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Gallatin
19:30—22:00
Poster Session 1

Gallatin

TUESDAY, JANUARY 10

07:00—08:00
Breakfast

Gallatin
08:00—11:30
Cell Types Contributing to the Plasticity of Tumor Microenvironment
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Jing Yang, University of California, San Diego, USA

* William A. Weiss†, University of California, San Francisco, USA

Peter F. Carmeliet, University of Leuven, VIB, Belgium
Endothelial versus Cancer Cell Metabolism

Thomas Tüting, Otto-von-Guericke University, Germany
Inflammation-Induced Phenotypic Plasticity of Tumor and Immune Cells as a Mechanism of Disease Progression and Therapy Resistance in Melanoma

Neta Erez, Tel Aviv University, Israel
Short Talk: Cancer-Associated Fibroblasts Link Tissue Damage with Tumor-Promoting Inflammation in Breast Cancer

Coffee Break

Valerie M. Weaver, University of California, San Francisco, USA
Extracellular Matrix and Tumor Mechanics

Shelly Peyton, University of Massachusetts, USA
Short Talk: Dynamics of Fibronectin Assembly and Tumor Cell Latency

Mathias Florian Heikenwälder, German Cancer Research Center, DKFZ, Germany
Kupffer-Cell Derived TNF Preferentially Triggers Cholangiocellular Carcinoma through JNK under Chronic Mitochondrial Dysfunction and ROS

Chen Hao Lo, Moffitt Cancer Center, USA
Poster Teaser: Temporal Dynamics of Macrophage Plasticity in Bone Metastatic Prostate Cancer

Magdolna Djurec, Spanish National Cancer Research Center, Spain
Poster Teaser: Reprogramming Cancer Associated Fibroblasts as a Therapeutic Approach against Pancreatic Ductal Adenocarcinoma

Ayse Nihan Kilinc, University of Basel, Switzerland
Poster Teaser: The Contribution of Epithelial-Mesenchymal Plasticity to Cancer Stemness

Lennart Kester, Hubrecht Institute, Netherlands
Poster Teaser: Clonal Dynamics with Single Cell Resolution in Different Stages of Colon Carcinoma

Natsuko Kimura, University of Tokyo, Japan
Poster Teaser: Maintenance of Stemness and Niche Environment of Breast Cancer Cells by FRS2beta, A Feedback Inhibitor for HER2-ERK Pathway, during Mammary Tumorigenesis

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Gallatin
13:00—22:00
Poster Viewing

Gallatin
16:30—17:00
Coffee Available

Lower Atrium
17:00—19:00
Plasticity of Immune Cells within the Tumor Microenvironment
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Mikala Egeblad, Cold Spring Harbor Laboratory, USA

* Janelle S. Ayres, The Salk Institute for Biological Studies, USA

Peter Friedl, NCMLS, Radboud University Nijmegen Medical Centre, Netherlands
Serial Killing of Tumor Cells – Impact of the Microenvironment

Giorgio Trinchieri, NCI, National Institutes of Health, USA
Cancer as a Meta-Organism – Fine-Tuning of Tumor Progression and Response to Therapy by Microbiota-Regulated Immune Cells

Melissa A. Meyer, Washington University in St. Louis, USA
Short Talk: Tumor-Induced IRF8 Deficiency Interrupts BATF3-Dependent Dendritic Cells Development

Garry P. Nolan, Stanford University, USA
In-Depth Molecular Analysis of Tumor and Progenitor Cell Heterogeneity

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Gallatin
19:30—22:00
Poster Session 2

Gallatin

WEDNESDAY, JANUARY 11

07:00—08:00
Breakfast

Gallatin
08:00—11:30
Parallels between Normal Tissue Repair Response and Oncogenesis
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Carla V. Rothlin, Yale University, USA

* Neta Erez, Tel Aviv University, Israel

Janelle S. Ayres, The Salk Institute for Biological Studies, USA
Innate Immune-Microbiota Interactions Protect from Cachexia

Raghu Kalluri, University of Texas MD Anderson Cancer Center, USA
The Functional Role of EMT and Exosomes in Pancreatic Cancer

Annelise Snyder, University of Washington, USA
Short Talk: Necroptotic Cell Death within the Tumor Microenvironment Promotes Tumor Control

Coffee Break

Sergei Grivennikov, Fox Chase Cancer Center, USA
Tumor-Elicited Inflammation and Cytokines at Crossroads in Wound Healing and Tumor Progression

Stefani Spranger, University of Chicago, USA
Short Talk: Impact of Tumor Cell-Intrinsic Signaling on Anti-Tumor Immune Responses in the Tumor Microenvironment

Robert F. Schwabe, Columbia University, USA
Fibrosis Promotes the Development of Liver Cancer

Mario A. Shields, Cold Spring Harbor Laboratory, USA
Poster Teaser: Lysyl Oxidases Suppress Pancreatic Cancer Progression and Inhibit FAK and ERK Signaling

Suzanne M. Ponik, University of Wisconsin-Madison, USA
Poster Teaser: Collagen Matrix Density Drives the Metabolic Profile Shift of Breast Cancer Cells

Danielle Seinstra, Hubrecht Institute, Netherlands
Poster Teaser: The Role of Cellular Heterogeneity in Chemotherapy Resistance in Breast Cancer Patients

Daniel C. Rabe, University of Chicago, USA
Poster Teaser: Exosome Crosstalk between Tumors and Tumor-Associated Macrophages Drives Pro-Invasive Plasticity

Julia Varga, Georg Speyer Haus, Germany
Poster Teaser: Notch3 Activation in Response to Aberrant Akt Signaling Contributes to Colorectal Cancer Progression

11:30—14:30
On Own for Lunch

11:30—13:00
Poster Setup

Gallatin
13:00—22:00
Poster Viewing

Gallatin
14:30—16:30
Workshop 2: Therapy Resistance Mediated by Adaptive Responses in the Tumor Microenvironment

Jefferson/Madison
* Weizhou Zhang, University of Iowa, USA
Obesity-Related NLRC4 Inflammasome Activation and Angiogenesis in Breast Cancer

Saran Kumar, Hebrew University, Israel
Adjacency to Blood Vessels as a Generator of Tumor Cell Metabolic and Phenotypic Heterogeneities

Mihaela Skobe, Icahn School of Medicine at Mount Sinai, USA
Lymphatic Endothelium Protects Breast Cancer Cells from Death by Inducing Metabolic Adaptations

Melissa R. Junttila, Genentech, Inc., USA
Identification of a Non-Genomic Resistance Mechanism to Vemurafenib in a BRAF Mutant Melanoma Model

Peter Chockley, University of Michigan Medical School, USA
EMT Confers Susceptibility to Metastasis-Specific Immune Surveillance in Lung Cancer

Alex Swarbrick, Garvan Institute of Medical Research, Australia
The Paracrine Hedgehog-FGF Axis Mediates Cancer Stem Cell Plasticity in Triple Negative Breast Cancer

* Ela Elyada, Cold Spring Harbor Laboratory, USA
Pancreatic Stellate Cell Dynamics in PDAC

Michael Timaner, Technion-Israel Institute of Technology, Israel
Tumor-Associated Mesenchymal Stem Cells Preserve Cancer Stem Cells Niche in the Tumor Microenvironment Following Chemotherapy

16:30—17:00
Coffee Available

Lower Atrium
17:00—19:00
Approaches to Visualize and Study Dynamics of Tumor Microenvironment (“Imaging”)
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Sergei Grivennikov, Fox Chase Cancer Center, USA

* Stefani Spranger, University of Chicago, USA

Mikala Egeblad, Cold Spring Harbor Laboratory, USA
Imaging Reveals Tumor and Stromal Contributions to Formation of Metastases

Jacco van Rheenen, Hubrecht Institute, Netherlands
Intravital Imaging of Stem Cell and Cancer Cell Plasticity

Tracy W. Liu, MD Anderson Cancer Center, USA
Short Talk: Imaging the Dynamics of Tumor NF-?B Transcriptional Activation and the Microenvironment In Vivo

Matthew F. Krummel, University of California, San Francisco, USA
Imaging and Deconvolving Tumor Antigen Flow in Primary and Metastatic Tumor Sites

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Gallatin
19:30—22:00
Poster Session 3

Gallatin

THURSDAY, JANUARY 12

07:00—08:00
Breakfast

Gallatin
08:00—11:15
Targeting Changing Tumor Microenvironment for Anti-Cancer Therapies
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Sheila A. Stewart†, Washington University School of Medicine, USA

* Andrew J. Ewald, Johns Hopkins University School of Medicine, USA

Karin E. de Visser, Netherlands Cancer Institute, Netherlands
Targeting Tumor-Induced Systemic Inflammation to Fight Metastatic Breast Cancer

Carla V. Rothlin, Yale University, USA
Innate Immune Checkpoints in Anti-Tumor Immunity

Deepak Nagrath, Rice University, USA
Short Talk: Targeting Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth

Coffee Break

Sandra S. McAllister, Brigham & Women's Hospital/Harvard Medical School, USA
Systemic Regulation of Tumor and Stromal Cell Plasticity

Lionel J. Apetoh, Centre Georges Francois Leclerc, France
Short Talk: Selective Degradation of the PU.1 Transcription Factor by Autophagy Represses TH9 Cell Differentiation

Erik A. Sahai, Cancer Research UK London Research Institute, UK
Tumor-Stroma Cross-Talk in Metastasis and Therapy Failure

11:15—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Lower Atrium
17:00—18:15
Therapy Resistance Mediated by Adaptive Responses in Tumor Microenvironment
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Karin E. de Visser, Netherlands Cancer Institute, Netherlands

* Erik A. Sahai, Cancer Research UK London Research Institute, UK

Francois Ghiringhelli, Centre de Recherche, INSERM U866, France
Chemotherapy and Reprogramming Immune and Cancer Cells

Miriam Merad, Mount Sinai School of Medicine, USA
High-Dimensional Analysis of Early Lung Cancer Myeloid Microenvironment

18:15—19:00
Closing Keynote Address
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
* Sergei Grivennikov, Fox Chase Cancer Center, USA

* Florian R. Greten, Institute for Tumor Biology and Experimental Therapy, Germany

* Mikala Egeblad, Cold Spring Harbor Laboratory, USA

Robert A. Weinberg, Massachusetts Institute of Technology, USA
The Epithelial-Mesenchymal Transition and Malignant Progression

19:00—19:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/08/2016

Jefferson/Madison
19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Gallatin
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Gallatin

FRIDAY, JANUARY 13

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Journal of Molecular Cell Biology (JMCB) Roche

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676