Copper Mountain Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2017


Here are the related meetings in 2018:
Selective Autophagy (Z2)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Autophagy Network Integration in Health and Disease (B2)


Organizer(s) Ivan Dikic, Katja Simon and J. Wade Harper
February 12—16, 2017
Copper Mountain Resort • Copper Mountain, Colorado USA
Discounted Abstract Deadline: Oct 11, 2016
Abstract Deadline: Nov 15, 2016
Scholarship Deadline: Oct 11, 2016
Discounted Registration Deadline: Dec 23, 2016

Sponsored by Cell Research, Novartis Institutes for BioMedical Research and Shire Human Genetic Therapies

Summary of Meeting:
Autophagy is a quality control mechanism that plays an important role in health and disease, including neurodegeneration, cancer, infection and inflammation. The core autophagy machinery has been identified and studied in detail. In addition, integration and cross-talk with other cellular pathways is becoming clearer, providing a rationale for why autophagy is linked to so many diverse physiological functions. Future challenges are focused on integrative structural, molecular and system approaches that are able to provide a much more refined understanding of autophagy regulatory networks. This meeting will highlight basic molecular and network insights in the autophagy system that are critical in life processes and multiple disease areas, and will examine the prospects for therapeutic targeting of the autophagy system. The meeting will bring together a variety of investigators exploring different facets of autophagy, and their interactions will expand our knowledge of fundamental autophagic mechanisms in different physiological and pathological settings.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, February 12 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 16 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 17 in order to fully experience the meeting.

SUNDAY, FEBRUARY 12

16:00—20:00
Arrival and Registration

Kokopelli's
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Kokopelli's

MONDAY, FEBRUARY 13

07:00—08:00
Breakfast

Kokopelli's
08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Ivan Dikic, Goethe University Medical School, Germany

* Katja Simon, University of Oxford, UK

Herbert (Skip) W. Virgin, Washington University School of Medicine, USA
Autophagy Genes in Inflammation, Infection and Immunity

09:00—12:00
Autophagy Systems
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Ivan Dikic, Goethe University Medical School, Germany

* Katja Simon, University of Oxford, UK

J. Wade Harper, Harvard Medical School, USA
Digitizing Ubiquitin Signaling for Mitophagy

Coffee Break

Sharon A. Tooze, Francis Crick Institute, UK
Distinct Roles of the Centrosomal Pool of GABARAP in Autophagy

Li Yu, Tsinghua University, China
Regulation and Function of Energy Deprivation Induced Autophagy

Liang Ge, University of California, Berkeley, USA
Mechanism of Autophagic Membrane Generation from the Endomembrane

Kiren Baines, University of Bristol, UK
Short Talk: The ATG5-ATG12 Conjugate Regulates Clathrin-Mediated Endocytosis to Control the Internalisation of Specific Cell Surface Proteins

12:00—14:30
On Own for Lunch

12:00—13:00
Poster Setup

Big Horn C
13:00—22:00
Poster Viewing

Big Horn C
14:30—16:30
Workshop 1: Autophagy Networks in Biology

Big Horn B
* Vladimir Denic, Harvard University, USA

* Erika L. F. Holzbaur, University of Pennsylvania, USA

Michael J. Morgan, University of Colorado Denver, USA
Selection for Metastasis Leads to Increased Sensitivity to Lysosomal Inhibitors

David P. Waterman, Brandeis University, USA
Autophagy in Response to DNA Damage

Lisa M. Lindqvist, Walter and Eliza Hall Institute of Medical Research, Australia
Autophagy Induced During the Early Stages of Mitochondrial-Mediated Apoptosis Helps to Keep Apoptotic Cells Immunologically Silent

Thomas Riffelmacher, Kennedy Institute, University of Oxford, UK
Autophagy in the Control of Granulocytic Differentiation

Song-Fa Zhang, Zhejiang University, China
Autophagy Maintains Ovarian Cancer Stem Cells Characteristics by Regulating FOXA2 expression

Chieko Kishi-Itakura, University of Cambridge, UK
Ultrastructural Insights into Pathogen Clearance by Autophagy

Anuradha Bhukel, Freie University of Berlin, Germany
Reduced Autophagy Mediates Memory Impairment in a Cell Non-Autonomous Manner in Drosophila

16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Structural and Molecular Anatomy of Autophagy Pathway
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Eric H. Baehrecke, University of Massachusetts Medical School, USA

* Michel Desjardins, University of Montreal, Canada

Vladimir Denic, Harvard University, USA
A Membrane-Associated Autophagy Signaling Pathway for Controlling Peroxisome Fate

James H. Hurley, University of California, Berkeley, USA
Regulation and Scaffolding of Autophagy Initiation

Zvulun Elazar, Weizmann Institute of Science, Israel
The Role of Autophagy in the Regulation of the TNF Receptor, FN14

Simon Wilkinson, MRC Institute of Genetics and Molecular Medicine, UK
Short Talk: Pancreatic Enzyme Biosynthesis is Quality Controlled by an ER-resident LC3- and FIP200-binding scaffold protein

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Kokopelli's
19:30—22:00
Poster Session 1

Big Horn C

TUESDAY, FEBRUARY 14

07:00—08:00
Breakfast

Kokopelli's
08:00—11:00
Conventional and Unconventional Autophagy Networks
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Felix Randow, Medical Research Council, UK

* Michel Desjardins, University of Montreal, Canada

Patrice Codogno, INSERM, France
Autophagy and Plasma Membrane Domains

Noboru Mizushima, University of Tokyo, Japan
Novel Methods for Monitoring Autophagosome Maturation and Autophagic Flux

Coffee Break

Christian Behrends, Ludwig Maximilians University München, Germany
Regulatory Circuits in Autophagy: Exploring the Function of SMCR8

Aditya Murthy, Genentech, Inc., USA
Regulation of Endosomal Toll-Like Receptor Signaling by Autophagy

Paula Coelho, McGill University, Canada
Short Talk: Decreased LC3C Expression in Cancers Uncouples Met RTK from Autophagic Regulation

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Big Horn C
13:00—22:00
Poster Viewing

Big Horn C
16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Autophagy Crosstalk with Other Pathways
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain

* David C. Rubinsztein, Cambridge Institute for Medical Research, UK

Malene Hansen, Sanford Burnham Prebys Medical Discovery Institute, USA
Cellular Recycling: Role of Autophagy in Aging and Disease

Eric H. Baehrecke, University of Massachusetts Medical School, USA
Vps13D Encodes a Ubiquitin Binding Protein that is Required for Mitochondrial Dynamics and Parkin-Dependent Mitophagy

Marja Jäättelä, Danish Cancer Society Research Center, Denmark
Lysosomal Control of Chromosome Segregation

Catherine Greene, University of Calgary, Canada
Short Talk: Novel Late Stage Phagolysosomal Events are Modulated by Key Autophagic Machinery

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Kokopelli's
19:30—22:00
Poster Session 2

Big Horn C

WEDNESDAY, FEBRUARY 15

07:00—08:00
Breakfast

Kokopelli's
08:00—11:00
Selective Autophagy
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Zvulun Elazar, Weizmann Institute of Science, Israel

* Marja Jäättelä, Danish Cancer Society Research Center, Denmark

Tamotsu Yoshimori, Osaka University, Japan
New Insights into Membrane Dynamics in Autophagy

Felix Randow, Medical Research Council, UK
How Autophagy Defends the Cytosol Against Bacterial Invasion

Coffee Break

Ivan Dikic, Goethe University Medical School, Germany
Conventional and Non-conventional Ubiquitination in Antibacterial Autophagy

Trey Ideker, University of California, San Diego, USA
Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy

Anja Barbara Hoffmann, Ruprecht Karls Universität Heidelberg, Germany
Short Talk: The Autophagic Pathway in Uukuniemi Virus Infection

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Big Horn C
13:00—22:00
Poster Viewing

Big Horn C
14:30—16:30
Workshop 2: Technology Talks

Big Horn B
* Trey Ideker, University of California, San Diego, USA

Erik Verschueren, Genentech, Inc., USA
Discovery of Specific Autophagy Signaling Adaptors through Quantitative Multiplexed Proteomics

Vinay Verghese Eapen, Harvard Medical School, USA
Defining the Role of Selective Autophagy Receptor-Cargo Interactions in Pancreatic Cancer Pathogenesis

Ben Loos, Stellenbosch University, South Africa
Mapping out the Autophagy Machinery - A Super-Resolution Approach

Alexandra Stolz, Goethe University Medical School, Germany
Fluorescence-Based ATG8 Sensors Monitor Localization and Function of LC3/GABARAP Proteins

Andreas Jenny, Albert Einstein College of Medicine, USA
A Genetic Model for Selective Endosomal Microautophagy in Drosophila

Mariam Aghajan, Ionis Pharmaceuticals, USA
ASO-Mediated Inhibition of Autophagy Protects Against Acetaminophen-Induced Liver Injury

Piyush Mishra, Jawaharlal Nehru Centre for Advanced Scientific Research, India
Discovery of Pan Autophagy Inhibitors through a High Throughput Screen Highlights Macroautophagy as an Evolutionarily Conserved Process Across Three Kingdoms

16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Autophagy in Neurons
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Christian Behrends, Ludwig Maximilians University München, Germany

Richard J. Youle, NINDS, National Institutes of Health, USA
Molecular Basis of Parkinson's Disease

Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain
Mitophagy in Neurons: From Development to Degeneration

Erika L. F. Holzbaur, University of Pennsylvania, USA
Autophagy in Neuronal Homeostasis and Neurodegeneration

Nicholas F. Endres, Genentech, Inc., USA
Short Talk: A Reversible Covalent Inhibitor of the Deubiquitinase USP30 Enhances Parkin Mediated Mitophagy

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Kokopelli's
19:30—22:00
Poster Session 3

Big Horn C

THURSDAY, FEBRUARY 16

07:00—08:00
Breakfast

Kokopelli's
08:00—11:00
Metabolism, Oncogenesis and Stem Cells
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Patrice Codogno, INSERM, France

* Noboru Mizushima, University of Tokyo, Japan

Eileen P. White, Rutgers University, USA
Autophagy-mediated Recycling Sustains Survival of Cancer Cells

Katja Simon, University of Oxford, UK
Autophagy Determines Immune Metabolism

Coffee Break

Jayanta Debnath, University of California, San Francisco, USA
Autophagy and Secretion

Alison Simmons, Weatherall Institute of Molecular Medicine, UK
Innate Immunity and Autophagy in Rare Intestinal Cell Subsets

Martin Graef, Max Planck Institute for Biology of Aging, Germany
Short Talk: Autophagosomal acyl-CoA Synthetases Activate Free Fatty Acids Essential for Autophagy

11:00—14:30
On Own for Lunch

16:30—17:00
Coffee Available

Kokopelli's
17:00—18:45
Targeting Autophagy Networks
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Sharon A. Tooze, Francis Crick Institute, UK

Michel Desjardins, University of Montreal, Canada
PINK1/Parkin are Key Regulators of Autophagy, Antigen Presentation and Autoimmune Diseases

David C. Rubinsztein, Cambridge Institute for Medical Research, UK
The Parkinson’s Disease-Associated Genes ATP13A2 and SYT11 Regulate Autophagy via a Common Pathway

Johara Chouitar, Takeda Boston, USA
Targeting Autophagy for Cancer Therapy

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* J. Wade Harper, Harvard Medical School, USA

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Big Horn C
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Big Horn C

FRIDAY, FEBRUARY 17

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Cell Research Novartis Institutes for BioMedical Research
Shire Human Genetic Therapies
 

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13CA210491-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge additional support for this conference from:

Journal of Molecular Biology

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676