Beaver Run Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

NOTES:
This meeting occurs in 2017.
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


Download Flyer

Twitter hashtag for this meeting: #KSgenome

Precision Genome Engineering (A2)

Scientific Organizers: J. Keith Joung, Emmanuelle Charpentier and Olivier Danos


January 8—12, 2017

Beaver Run Resort, Breckenridge, Colorado, USA


Sponsored by Biogen, Editas Medicine, Inc., Novo Nordisk A/S, Regeneron Pharmaceuticals, Inc., Sangamo BioSciences, Inc. and Thermo Fisher Scientific Inc.


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
Scholarship Deadline: Sep 19, 2016 [details]
Discounted Abstract Deadline: Sep 19, 2016 [details]
Abstract Deadline: Oct 6, 2016 [details]
Discounted Registration Deadline: Nov 9, 2016 [details]

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2017-A2 "Precision Genome Engineering" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On September 19, 2016 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After September 19, 2016 until December 5, 2016 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
September 19, 2016 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 9, 2016 795.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After November 9, 2016 945.00 USD
Discounted STUDENT Registration
More details
Before and On November 9, 2016 570.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After November 9, 2016 720.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: September 19, 2016


Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is October 6, 2016)

Global Health Travel Award Deadline:


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: September 19, 2016


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: October 6, 2016


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is September 19, 2016)

Discounted Registration Deadline: November 9, 2016


Registration Fee: 795.00 USD* (includes 150.00 USD discount)
Student Registration Fee: 570.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 945.00 USD*
Student Registration Fee: 720.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, January 8 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 12 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 13 in order to fully experience the meeting.

SUNDAY, JANUARY 8

16:00—20:00
Arrival and Registration

Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Foyer

MONDAY, JANUARY 9

07:00—08:00
Breakfast

Summit Gallery
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 12/08/2016
Provide an overview of ongoing clinical trials that are based on or utilize genome-editing technologies. Discuss on-going and future challenges to further translation.

Colorado Ballroom
* J. Keith Joung, Massachusetts General Hospital, USA

Luigi M. Naldini, San Raffaele Telethon Institute, Italy
Precision Genome Engineering of Human Hematopoiesis for Treating Genetic Disease and Cancer

09:00—11:30
(Basic) Science of Recombination & DNA Repair
Registered attendees can view abstracts starting on 12/08/2016

Colorado Ballroom
* Emmanuelle Charpentier, Max Planck Institute for Infection Biology, Humboldt University and The Laboratory for Molecular Infection Medicine Sweden, Germany

David R. Liu, Harvard University, USA
Base Editing: Genome Editing without Double-Stranded DNA Cleavage

Coffee Break

Maria Jasin, Memorial Sloan Kettering Cancer Center, USA
DNA Repair Mechanisms and Genome Engineering

Frederick W. Alt, Boston Children's Hospital, USA
Recurrent DNA Break Cluster Genes in Neural Development, Diversification and Disease: Potential Analogies to Lymphocyte Rearrangement Processes

Jean-Yves Masson, Laval University Cancer Research Center, Canada
Short Talk: Regulation of the Tumor Suppressor PALB2: A Critical Player for Homologous Recombination at a CRISPR/Cas9-Induced DNA Double-Strand Break

Katherine S. Pawelczak, NERx Biosciences, USA
Short Talk: Chemical Enhancement of CRISPR/Cas9 Mediated Site-Specific Genome Engineering using Novel Inhibitors of the Ku-DNA Interaction

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Breckenridge Ballroom
13:00—22:00
Poster Viewing

Breckenridge Ballroom
14:30—15:30
Workshop 1: In vivo Delivery of Genome Editing Nucleases

Colorado Ballroom
15:30—16:30
Workshop 2: Ex vivo or in vitro Delivery of Genome Editing Nucleases

Colorado Ballroom
* Luigi M. Naldini, San Raffaele Telethon Institute, Italy

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Latest Advances in Genome-Editing Nuclease Technologies I
Registered attendees can view abstracts starting on 12/08/2016

Colorado Ballroom
* J. Keith Joung, Massachusetts General Hospital, USA

Ralf Kuhn, Max-Delbrueck Center, Germany
Stimulation of Homology-Directed Repair at CRISPR/Cas9-Induced Double-Strand Breaks

Edward J. Rebar, Sangamo Biosciences, USA
New Zinc Finger Nuclease Architectures for Precision Genome Engineering

Jay Ashok Shendure, University of Washington, USA
Applications of Genome Editing in Developmental Biology and Human Genetics

Amit Choudhary, Harvard Medical School, USA
Short Talk: Chemical Control of CRISPR-Cas9 in Cells and Organisms

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Breckenridge Ballroom
19:30—22:00
Poster Session 1

Breckenridge Ballroom

TUESDAY, JANUARY 10

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Latest Advances in Genome-Editing Nuclease Technologies II
Registered attendees can view abstracts starting on 12/08/2016

Colorado Ballroom
* Jennifer A. Doudna, HHMI/University of California, Berkeley, USA

Feng Zhang, Broad Institute of MIT and Harvard University, USA
Expanding the CRISPR-Cas Genome Engineering Toolbox

Andy May, Caribou Biosciences, Inc., USA
DNA Repair Outcomes Following Cas9 Double-Stranded Breaks

Coffee Break

J. Keith Joung, Massachusetts General Hospital, USA
Defining, Optimizing and Changing the Specificities of CRISPR-Cas Nucleases

Sarah Jacobi, Integrated DNA Technologies, USA
Short Talk: Efficient Homology-Directed Repair using Long Single-Stranded DNA Templates

Channabasavaiah B. Gurumurthy, University of Nebraska Medical Center, USA
Short Talk: Easi-CRISPR: A Simple and Efficient Method for Creating Reporter and Conditional Knockout Animal Models

Fuqiang Chen, MilliporeSigma, USA
Short Talk: Improvement of CRISPR Activity and Specificity via Proximal Binding of Multiple CRISPR/Cas Systems (proxy-CRISPR)

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Breckenridge Ballroom
13:00—22:00
Poster Viewing

Breckenridge Ballroom
14:30—15:30
Workshop 3: Genome-Wide Specificities and Off-Target Effects of Genome Editing Nucleases

Colorado Ballroom
* J. Keith Joung, Massachusetts General Hospital, USA

15:30—16:30
Workshop 4: Design of Individual gRNAs and Genome-Wide Libraries of gRNAs for CRISPR-Cas Nucleases

Colorado Ballroom
* John G. Doench, Broad Institute of MIT and Harvard University, USA

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Biology of CRISPR Systems
Registered attendees can view abstracts starting on 12/08/2016
Updates on cutting-edge basic science studies of CRISPR systems. Not just Cas9 but extend to other aspects of the system (e.g., Cas1/Cas2, sequence-specific ribonucleases).

Colorado Ballroom
* Maria Jasin, Memorial Sloan Kettering Cancer Center, USA

Emmanuelle Charpentier, Max Planck Institute for Infection Biology, Humboldt University and The Laboratory for Molecular Infection Medicine Sweden, Germany
CRISPR-Cas9: An Ancient Bacterial Immune System Harnessed for Genome Engineering

Eugene V. Koonin, National Institutes of Health, USA
Discovery of Novel CRISPR-Cas Systems by Genome and Metagenome Sequence Database Mining and Evolution of Adaptive Immunity in Prokaryotes

Joshua Keith Young, Dupont Pioneer, USA
Short Talk: Identification and Characterization of Novel Cas9 Endonucleases

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Breckenridge Ballroom
19:30—22:00
Poster Session 2

Breckenridge Ballroom

WEDNESDAY, JANUARY 11

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Research Applications of Genome & Epigenome Engineering I
Registered attendees can view abstracts starting on 12/08/2016

Colorado Ballroom
* Barbara J. Meyer, University of California, Berkeley, USA

Jonathan S. Weissman, University of California, San Francisco, USA
Applications of CRISPR-Cas9-Based Gene Regulatory Proteins

Angelo Lombardo, San Raffaele Telethon Institute for Gene Therapy, Italy
Therapeutic Applications of Epigenome Editing

Coffee Break

Jennifer A. Doudna, HHMI/University of California, Berkeley, USA
Mechanism and Delivery of RNA-Guided Genome Engineering Proteins

Alister Funnell, Altius Institute for Biomedical Sciences, USA
Short Talk: Functional Characterization of Putative Regulatory Elements by Precision Genome Engineering

Robert J. Ihry, Novartis Institutes for BioMedical Research, USA
Short Talk: p53 Inhibition Enhances CRISPR/CAS9 Engineering in Human Pluripotent Stem Cells by Blocking DSB-Induced Toxicity

Shashank Patel, NCI, National Institutes of Health, USA
Short Talk: A Genome-Scale CRISPR Screen to Identify Essential Genes for T Cell Based Cancer Therapies

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Breckenridge Ballroom
13:00—22:00
Poster Viewing

Breckenridge Ballroom
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Research Applications of Genome & Epigenome Engineering II
Registered attendees can view abstracts starting on 12/08/2016

Colorado Ballroom
* Angelo Lombardo, San Raffaele Telethon Institute for Gene Therapy, Italy

Barbara J. Meyer, University of California, Berkeley, USA
Genome Editing of C. elegans and Other Non-Model Organisms

Daniel F. Voytas, University of Minnesota, USA
Precise Engineering of Plant Genomes

Andrea Crisanti, Imperial College London, UK
Building and Testing CRISPR-Based Gene Drives for Population Control in the Malaria Mosquito

Alex Marson, University of California, San Francisco, USA
Short Talk: Discovery of an Autoimmunity-Associated IL2RA Enhancer by Unbiased Targeting of Transcriptional Activation

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Breckenridge Ballroom
19:30—22:00
Poster Session 3

Breckenridge Ballroom

THURSDAY, JANUARY 12

07:00—08:00
Breakfast

Summit Gallery
08:00—11:15
Novel Technologies for Therapeutic Application of Genome Engineering
Registered attendees can view abstracts starting on 12/08/2016

Colorado Ballroom
* Olivier Danos, Biogen, USA

Vic E. Myer, Editas Medicine, USA
Industrial Scale Lead Finding and Optimization for Genomic Medicines

Daniel G. Anderson, Massachusetts Institute of Technology, USA
Nucleic Acid Delivery Systems for RNA Therapy and Gene Editing

Coffee Break

James M. Wilson, University of Pennsylvania, USA
In vivo Genome Editing of Liver for Treating Metabolic Disease

Mark A. Kay, Stanford University, USA
rAAV-Mediated Genome Editing without the Use of Nucleases

Bin Li, Ohio State University, USA
Short Talk: Lipid-like Nanoparticles for mRNA Delivery in vivo

Knut Woltjen, CiRA, Kyoto University, Japan
Short Talk: Simultaneous Derivation of Disease-Relevant Point-Mutants and Concordant Isogenic Clones from Human Induced Pluripotent Stem Cells

11:15—17:00
On Own for Lunch

14:30—16:30
Workshop 5: Ethics and Human Rights

Colorado Ballroom
* George J. Annas, Boston University School of Public Health, USA
Why Precision Genome Engineering Should Not Be Used to (Try to) Make a "Better Baby"

Peter Dabrock, FAU Erlangen-Nürnberg, Germany
“Do Not Throw the Baby Out with the Bathwater” – Societal, Ethical and Governance Challenges of Precision Genome Engineering for Science and Society

Evelyne Shuster, Veterans Affairs Medical Center, USA
Editing the “Book of Life”: Too Early to Prescribe?

16:30—17:00
Coffee Available

Foyer
17:00—18:45
Therapeutic Applications of Genome Engineering
Registered attendees can view abstracts starting on 12/08/2016

Colorado Ballroom
* Mark A. Kay, Stanford University, USA

Andrew M. Scharenberg, University of Washington, USA
Translational Genome Editing

Philippe N. Duchateau, Cellectis SA, France
TALEN®-Based Targeted Genome Modifications for Improved CAR T-Cell Adoptive Immunotherapy

Linhong Li, MaxCyte, Inc., USA
Short Talk: Mutation Correction of X-linked Chronic Granulomatous Disease

Sateesh Krishnamurthy, University of Iowa, USA
Short Talk: Correction of CFTR Splicing Mutation by Using CRISPR/Cas9 Genome Editing and Non-Homologous End Joining

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/08/2016

Colorado Ballroom
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Breckenridge Ballroom
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Breckenridge Ballroom

FRIDAY, JANUARY 13

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Biogen Editas Medicine, Inc.
Novo Nordisk A/S Regeneron Pharmaceuticals, Inc.
Sangamo BioSciences, Inc. Thermo Fisher Scientific Inc.

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Charles River MYcroarray
Synthego
 

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Editas Medicine, Inc.


Sangamo BioSciences, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676