Sheraton Seattle Hotel Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

NOTES:
This meeting occurs in 2017.
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


Download Flyer

Twitter hashtag for this meeting: #KSepigen

Epigenetics and Human Disease: Progress from Mechanisms to Therapeutics (A9)

Scientific Organizers: Johnathan R. Whetstine, Jessica K. Tyler and Rab K. Prinjha


January 29—February 2, 2017

Sheraton Seattle Hotel, Seattle, Washington, USA


Sponsored by Incyte Corporation, Taylor & Francis and Vertex Pharmaceuticals Incorporated


IT’S NOT TOO LATE TO SUBMIT YOUR ABSTRACT. Abstracts received can no longer be considered for oral short talks; poster display opportunities remain open.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
Scholarship Deadline: Sep 29, 2016 [details]
Discounted Abstract Deadline: Sep 29, 2016 [details]
Abstract Deadline: Oct 27, 2016 [details]
Discounted Registration Deadline: Nov 30, 2016 [details]

Click here to view Cancellation Policy

Submit an Abstract Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2017-A9 "Epigenetics and Human Disease: Progress from Mechanisms to Therapeutics" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On September 29, 2016 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After September 29, 2016 until January 5, 2017 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
September 29, 2016 n/a
Discounted NON-STUDENT Registration
More details
Before and On November 30, 2016 795.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After November 30, 2016 945.00 USD
Discounted STUDENT Registration
More details
Before and On November 30, 2016 570.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After November 30, 2016 720.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: September 29, 2016


Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is October 27, 2016)

Global Health Travel Award Deadline:


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: September 29, 2016


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: October 27, 2016


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is September 29, 2016)

Discounted Registration Deadline: November 30, 2016


Registration Fee: 795.00 USD* (includes 150.00 USD discount)
Student Registration Fee: 570.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 945.00 USD*
Student Registration Fee: 720.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, January 29 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 2 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 3 in order to fully experience the meeting.

SUNDAY, JANUARY 29

16:00—20:00
Arrival and Registration

Grand Ballroom Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Grand Ballroom Foyer

MONDAY, JANUARY 30

07:30—08:30
Breakfast

Grand Ballroom AB
08:30—09:30
Welcome and Keynote Address
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* Johnathan R. Whetstine, Massachusetts General Hospital, USA

* Jessica K. Tyler, Weill Cornell Medicine, USA

* Rab K. Prinjha, GlaxoSmithKline, UK

Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA
Epigenetics, Stem Cells and Disease Research

09:30—11:45
Epigenetics and Genome Organization
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* Bradley E. Bernstein, Massachusetts General Hospital, USA

Thomas Misteli, NCI, National Institutes of Health, USA
Deep Imaging of the Genome

Coffee Break

Bas van Steensel, Netherlands Cancer Institute, Netherlands
Architecture, Dynamics and Function of Genome - Nuclear Lamina Interactions

Kadir Akdemir, MD Anderson Cancer Center, USA
Short Talk: Spatial Organization of the Genome & Structural Alterations in Human Cancers

Robert Hansel-Hertsch, University of Cambridge, UK
Short Talk: G-Quadruplex Structures Mark Human Regulatory Chromatin

Janneke Peeters†, University Medical Center Utrecht, Netherlands
Short Talk: Enhancers in Autoimmune Disease Cells Contribute to Disease Pathogenesis and Can be Targeted to Reduce Autoimmunity

11:45—17:00
On Own for Lunch

11:45—13:00
Poster Setup

Grand Ballroom AB
13:00—22:00
Poster Viewing

Grand Ballroom AB
16:30—17:00
Coffee Available

Grand Ballroom Foyer
17:00—19:00
From Epigenomics to Disease
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* Henk Stunnenberg, Radboud University, Netherlands

Bradley E. Bernstein, Massachusetts General Hospital, USA
Epigenetic Mechanisms of Tumor Initiation and Evolution

Joseph F. Costello, University of California, San Francisco, USA
Losing Driver Mutations, Gaining Insight into Epigenome Evolution

John A. Stamatoyannopoulos, University of Washington, USA
A Roadmap to the Living Genome

Daniel S. Day†, Whitehead Institute, USA
Short Talk: Tumor Progression through Sequential Disruption of Insulated Neighborhoods

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Grand Ballroom AB
19:30—22:00
Poster Session 1

Grand Ballroom AB

TUESDAY, JANUARY 31

07:30—08:30
Breakfast

Grand Ballroom AB
08:30—11:30
Epigenetic Modification Dynamics: Gateway to Understanding Disease
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* Jessica K. Tyler, Weill Cornell Medicine, USA

Henk Stunnenberg, Radboud University, Netherlands
Epigenomics Uncovers Dysregulated Regulatory Pathways

Shelley L. Berger, University of Pennsylvania, USA
Chromatin Changes in Eukaryotic Senescence and Aging

Coffee Break

Anne Schaefer, Mount Sinai School of Medicine, USA
Polycomb Repressive Complex 2 (PRC2) Silences Genes Responsible for Neurodegeneration

Robert E. Kingston, Massachusetts General Hospital, USA
Nucleosome Compaction as a Regulatory Mechanism during Development

Panagiotis Ntziachristos†, Northwestern University, USA
Short Talk: Targeting Histone Deubiquitination in Acute Leukemia

Woojin An†, University of Southern California, USA
Short Talk: MacroH2A Suppresses Prostate Cancer Bone Metastasis through Cooperation with HP1 and H1.2

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Grand Ballroom AB
13:00—22:00
Poster Viewing

Grand Ballroom AB
16:30—17:00
Coffee Available

Grand Ballroom Foyer
17:00—19:00
Chromatin Modifiers, Development and Disease
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* Anne Schaefer, Mount Sinai School of Medicine, USA

Jessica K. Tyler, Weill Cornell Medicine, USA
Chromatin Assembly and Disassembly

Kristian Helin, University of Copenhagen, Denmark
Histone Methylation in Differentiation and Disease

Johnathan R. Whetstine, Massachusetts General Hospital, USA
Epigenetic Mechanisms Impact Cell Cycle and Somatic DNA Copy Number

Peter W. Lewis†, University of Wisconsin-Madison, USA
Short Talk: H3 K36M Oncohistone Promotes Sarcomagenesis through Altered Methylation Landscape

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Grand Ballroom AB
19:30—22:00
Poster Session 2

Grand Ballroom AB

WEDNESDAY, FEBRUARY 1

07:30—08:30
Breakfast

Grand Ballroom AB
08:00—08:30
Poster Setup

Grand Ballroom AB
08:30—17:00
Poster Viewing

Grand Ballroom AB
08:30—11:30
Epigenetics and Cell States
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* François Fuks†, Université Libre De Bruxelles, Belgium

Emily Bernstein, Mount Sinai School of Medicine, USA
Epigenetic Sensitivities in Cancer

Luciano Di Croce, Centre for Genomic Regulation, Spain
Unveiling Polycomb Functions in Stem Cells and Cancer

Coffee Break

Maria-Elena Torres-Padilla, Helmholtz Centre Munich, Germany
Epigenetic Mechanisms in Early Mammalian Development

Gerald R. Crabtree, Stanford University, USA
Chromatin Remodeling: Insights from the Genetics of Human Disease and New Methods

Elizabeth Heller, University of Pennsylvania, USA
Short Talk: Targeted Neuroepigenetic Editing of Cdk5 Regulates Behavior

Ana Patricia Gomes, Weill Cornell Medicine, USA
Short Talk: The CAF1 Complex Promotes Tumor Progression through Re-Distribution of Histone H3.3 in the Chromatin

11:30—12:30
Lunch

Grand Ballroom AB
12:00—14:30
Poster Session 3

Grand Ballroom AB
14:30—16:30
Workshop: Breakthroughs in Technology and Disease

Grand Ballroom CD
* Cheryl Arrowsmith, University of Toronto, Canada

Hatice Efsun Arda†, Stanford University, USA
Lineage Specific Regulomes of the Human Pancreas

Manfred Jung†, University of Freiburg, Germany
Chemical Tools for Methyl Lysine Readers

Victoria Le, The Salk Institute of Biological Studies, USA
Finding Translocations in Cancer Genomes using Chromatin Interaction Data

Tonya Marie Gilbert†, Massachusetts General Hospital, USA
In vivo Neuroepigenetic Imaging in Schizophrenia using Combined MR-PET

Ari Allyn-Feuer†, University of Michigan Medical School, USA
The Pharmacogenomics Informatics Pipeline: An Integrative Multi-Omics Platform for Variant Discovery

Nabieh Ayoub†, Technion University, Israel
Characterizing the Biological Functions of KDM4A-D Interactions with RNA Molecules

Shinya Oki†, Kyushu University, Japan
The Transcription Factor Landscape Decodes the Enhancers and Risk Variants in Non-Coding Regions

Yael David, Memorial Sloan Kettering Cancer Center, USA
Towards Synthetic Chromatin: Modifying Histones In Live Cells Using Protein Trans-Splicing

16:30—17:00
Coffee Available

Grand Ballroom Foyer
17:00—19:15
Epigenetic States and RNA
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* Emily Bernstein, Mount Sinai School of Medicine, USA

Tony Kouzarides, University of Cambridge, UK
Epigenetic Modification of RNA

Ramin Shiekhattar, University of Miami, USA
Targeting Integrator in Cancer

Ali Shilatifard, Northwestern University, USA
Principles of Epigenetics and Chromatin in Development and Human Disease

Karla Maria Rubio†, Max Planck Institute for Heart and Lung Research, Germany
Short Talk: Nuclear miRNA/exosome-Mediated Transcriptional Silencing within the Context of TGFB1 Signaling and Idiopathic Pulmonary Fibrosis

19:15
On Own for Dinner


THURSDAY, FEBRUARY 2

07:30—08:30
Breakfast

Grand Ballroom AB
08:30—11:30
Targeting Epigenetics
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* Johnathan R. Whetstine, Massachusetts General Hospital, USA

Rab K. Prinjha, GlaxoSmithKline, UK
Clinical Progression of BET Inhibitors

Cheryl Arrowsmith, University of Toronto, Canada
Probing the Epigenome for New Therapeutic Opportunities

Coffee Break

Alexander Tarakhovsky, Rockefeller University, USA
Uncovering Histone Mimics and Disease

Jesse J. Smith, Epizyme, USA
The EZH2 Inhibitor Tazemetostat as a Potential Therapeutic for Non-Hodgkin Lymphoma and Genetically Defined Solid Tumors

Norm Wong, Resverlogix Corporation, Canada
Short Talk: Selective BET Inhibitors are Useful for Normalizing Inflammation Leading to Reduced Cardiovascular Disease (CVD) in Humans and in an Animal Model of Rheumatoid Arthritis

Shaokun Shu†, Dana Farber Cancer Institute, USA
Short Talk: Response and Resistance to BET Bromodomain Inhibitors in Triple Negative Breast Cancer

11:30—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Grand Ballroom Foyer
17:00—18:45
Epigenetics and Therapy
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
* Rab K. Prinjha, GlaxoSmithKline, UK

Tamara Maes, Oryzon Genomics, Spain
Development of Lysine Specific Demethylase Inhibitors for Oncological and Neurodegenerative Disease

Dineo Khabele, Vanderbilt University, USA
Novel Epigenetic Drug Regimens to Enhance PARP Inhibitor Efficacy in Ovarian Cancer

Patrick Trojer, Constellation Pharmaceuticals, USA
Targeting Histone Lysine Methylation in Cancer

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 12/29/2016

Grand Ballroom CD
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Grand Ballroom AB
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Grand Ballroom AB

FRIDAY, FEBRUARY 3

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Incyte Corporation Taylor & Francis
Vertex Pharmaceuticals Incorporated
 

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Zymo Research Corporation

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Epizyme, Inc.


GlaxoSmithKline UK


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676