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This meeting took place in 2001



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Cancer Intervention (C6)


Organizer(s) George F. Vande Woude, Sara A. Courtneidge and Frank McCormick
February 28—March 5, 2001
Sheraton Tamarron Resort • Durango, Colorado USA
Abstract Deadline: Oct 27, 2000
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 28, 2000

Sponsored by Abbott Laboratories

Summary of Meeting:
After decades of research into the vast numbers of factors that contribute to cancer, we are beginning to exploit this knowledge in developing new prevention and cancer treatment strategies. There are now hundreds of new therapies and drugs being evaluated and in the next decade we expect to see remarkable improvements in the way we deal with cancer, from drugs that specifically target the products of cancer genes, to novel compounds that reduce cancer risk. Small molecule inhibitors are in clinical trials that target kinases, as are engineered viral vectors that target tumors deficient in tumor suppressor genes, immunotoxins and cancer “vaccines” that target tumor cells and therapeutics that reduce risk in individuals with inherited predispositions. No one is quite sure how well they will work and with current procedures there are enormous obstacles and delays in evaluating their potential. In addition, there is still a need to improve on the use of chemotherapeutic drugs and the application of existing therapies, when combined with advancements in diagnostic and imaging technologies. The purpose of this conference will be to explore progress on these fronts by inviting the leading investigators in cancer intervention strategies.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


WEDNESDAY, FEBRUARY 28

14:00—19:00
Registration

Alcove
19:15—20:15
Welcome

Windom Peak
20:15—20:30
Orientation

Silverton
20:30—21:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Silverton

THURSDAY, MARCH 1

07:00—08:00
Breakfast

Windom Peak
08:00—11:00
Novel Targets/Novel Therapeutics I
Meeting has ended...abstracts no longer viewable online.

Silverton
Hamilton Jordan, Hamilton Jordan, USA
Keynote Address:

Brian J. Druker, Oregon Health & Science University Cancer Institute, USA
STI571: A Tyrosine Kinase Inhibitor for the Treatment of CML – Validating the Promise of Molecularly Targeted Therapy

Dennis J. Slamon, University of California, Los Angeles, USA
Use of the Anti HER-2/neu Antibody Herceptin in the Treatment of Human Breast Cancer: Biologic Rational and Clinical Results

* John Mendelsohn, University of Texas, USA
Inhibitition of EGF Receptors as Anticancer Therapy

09:20—09:40
Coffee Break

Windom Peak
11:00—13:00
Poster Setup

Innisbrook/Animas
16:00—18:00
POSTER SESSION 1: Novel Targets/Novel Therapeutics

Innisbrook/Animas
17:00—18:00
Social Hour

Innisbrook Foyer
20:00—21:00
Coffee Available

Windom Peak
20:00—22:00
Novel Targets/Novel Therapeutics II
Meeting has ended...abstracts no longer viewable online.

Silverton
Edward A. Sausville, University of Maryland, USA
Optimizing Cytotoxic and Cytostatic Endpoints: How to?

* Vishva M. Dixit, Genentech, Inc., USA
Identification of Components of the Cell Death Pathway

Julian H. Downward, Cancer Research UK, UK
Oncogene Regulation of Cell Death


FRIDAY, MARCH 2

07:00—08:00
Breakfast

Windom Peak
08:00—11:00
Profiling of Cancers and Treatments
Meeting has ended...abstracts no longer viewable online.

Silverton
* Robert L. Strausberg, National Institutes of Health, USA
The Cancer Genome Anatomy Project: Reading the Molecular Signatures of Cancer

Donna G. Albertson, University of California, San Francisco, USA
Measurement of DNA Sequence Copy Number Using Comparative Genomic Hybridization to Microarrays

Dai Fukumura, Massachusetts General Hospital, USA
In vivo Imaging of Gene Expression and Physiological Function in Tumors

09:20—09:40
Coffee Break

Windom Peak
11:00—13:00
Poster Setup

Innisbrook/Animas
16:00—18:00
POSTER SESSION 2 & 3: Profiling of Cancers and Treatments/Cancer Prevention/Preclinical Models/New Approaches/Invasion/Metastasis/Angiogenesis/Biological Therapy

Innisbrook/Animas
17:00—18:00
Social Hour

Innisbrook Foyer
20:00—21:00
Coffee Available

Windom Peak
20:00—22:00
Cancer Prevention
Meeting has ended...abstracts no longer viewable online.

Silverton
Leslie Ford, National Cancer Institute, National Institutes of Health, USA
Study of Tamoxifen and Raloxifene (STAR) - An Intervention to Reduce Breast Cancer Risk

* Alice S. Whittemore, Stanford University, USA
Genetic Predisposition to Prostate Cancer: Possible Explanations for Ethnic Differences in Risk


SATURDAY, MARCH 3

07:00—08:00
Breakfast

Windom Peak
08:00—11:00
Preclinical Models
Meeting has ended...abstracts no longer viewable online.

Silverton
* Douglas Hanahan, ISREC, Switzerland
Prototyping Multistage Carcinogenesis in Mice: Elaborating Mechanisms and Assessing Strategies for Prevention and Therapy

Tyler Jacks, Massachusetts Institute of Technology, USA
Modeling Human Lung Cancer in Mice: Similarities and Shortcomings

Ronald A. DePinho, University of Texas MD Anderson Cancer Center, USA
Telomerase and Tumor Therapy

Martin Oft, ARMO BioSciences, USA
Genetic Control of Tumor Susceptibility in the Mouse

09:20—09:40
Coffee Break

Windom Peak
11:00—13:00
Poster Setup

Innisbrook/Animas
16:00—18:00
POSTER VIEWING ALL SESSIONS

Innisbrook/Animas
17:00—18:00
Social Hour

Innisbrook Foyer
20:00—21:00
Coffee Available

Windom Peak
20:00—22:00
New Approaches
Meeting has ended...abstracts no longer viewable online.

Silverton
Robert E. Wittes, Memorial Sloan-Kettering Cancer Center, USA
Keynote Speaker: Molecular Targeting and Clinical Oncology

Frank McCormick, University of California, San Francisco, USA
Oncolytic Viruses

William G. Kaelin, Jr., Dana-Farber Cancer Institute, USA
Anticancer Strategies Based on Functional Inactivation of the Retinoblastoma Protein


SUNDAY, MARCH 4

07:00—08:00
Breakfast

Windom Peak
08:00—11:00
Invasion/Metastasis/Angiogenesis
Meeting has ended...abstracts no longer viewable online.

Silverton
Ann F. Chambers, London Regional Cancer Centre, Canada
Metastasis: Mechanisms and Therapeutic Targets

Charles Streuli, University of Manchester, UK
Adhesion and Apoptosis: Novel Targets for Intervention

* Zena Werb, University of California, San Francisco, USA
The Role of Matrix Metalloproteinases in Neoplasia

09:20—09:40
Coffee Break

Windom Peak
16:00—17:00
Coffee Available

Windom Peak
15:30—17:30
Biological Therapy
Meeting has ended...abstracts no longer viewable online.

Silverton
Douglas Lowy, National Cancer Institute, National Institutes of Health, USA
Viral Vaccines

* James P. Allison, University of Texas MD Anderson Cancer Center, USA
Augmenting Anti-Tumor Immune Responses by Manipulation of T Cell Regulatory Signals

19:00—20:00
Social Hour

Windom Peak
20:00—22:00
Banquet

Silverton
21:00—00:00
Entertainment

Silverton

MONDAY, MARCH 5

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 CA88800-01




We gratefully acknowledge additional support for this conference from:

Abbott Laboratories

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