Banff Centre Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2002



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Angiogenesis in Cancer and Other Diseases: From Genes to Function to Therapy (Z2)


Organizer(s) Rakesh K. Jain, Peter M. Carmeliet and James M. Pluda
February 8—13, 2002
Banff Centre • Banff, Alberta Canada
Abstract Deadline: Oct 8, 2001
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 7, 2001

Sponsored by Novartis Pharmaceuticals Corporation


Summary of Meeting:
Pathological angiogenesis is a hallmark of cancer and various ischemic and inflammatory diseases. Concerted efforts in this area of research are leading to the discovery of a growing number of pro- and anti-angiogenic molecules, some of which are already in clinical trials. The complex interactions among these molecules and their effect on vascular structure and function in different environments are beginning to be elucidated. This integrated understanding is leading to the development of a number of exciting and bold approaches to treat cancer and other diseases. However, there are several outstanding questions that must be addressed for successful translation of discoveries from the bench to the bedside. With advances in molecular genetics and the availability of molecular probes, imaging technologies, and therapeutic opportunities, we are now beginning to answer these questions. In this meeting, we discuss how normal and abnormal blood vessels form, how they function, what molecules (genes) are involved, how they are used for therapy, why caution is warranted and what key questions remain unanswered. We will first discuss tumor angiogenesis since it is most widely studied, and then, the emerging role of angiogenesis and vascular remodeling in non-neoplastic disorders resulting from ischemia, inflammation, obesity and vascular malformations.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


FRIDAY, FEBRUARY 8

16:00—19:00
Registration

Eric Harvey Foyer
18:15—19:15
Welcome

Eric Harvey Foyer
19:15—19:30
Orientation

Eric Harvey Theatre
19:30—22:00
Keynote Addresses (Joint) Sponsored in part by OSI Pharmaceuticals, Inc.
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
* David A. Cheresh, University of California, San Diego, USA

* Rakesh K. Jain, Massachusetts General Hospital and Harvard Medical School, USA

Bjorn Reino Olsen, Harvard Medical School, USA
Molecular Mechanisms of Endostatin: Lessons from Collagen XVIII Knock-Out Mice

M. Amin Arnaout, Massachusetts General Hospital, USA
Crystal Structure of Heterodimeric Integrin aVb3.

M. Judah Folkman, Children's Hospital Boston, USA
Anti-Angiogenic Therapy of Cancer: Lessons from the Clinical Trials


SATURDAY, FEBRUARY 9

07:00—08:00
Breakfast

Donald Cameron Hall
08:00—11:00
Endothelial Stem Cells and Vascular Development
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
* Shahin Rafii, Weill Cornell Medical College, USA
Co-Recruitment of Marrow-Derived VEGFR1 (+)Hematopoietic and VEGFR2+ Vasculogenic Progenitors Cells by Angiogenic Factors is Essential for Angiogenesis.

Jun Yamashita, Kyoto University Graduate School of Medicine, Japan
Vascular Progenitor Cells Common to Endothelial and Mural Cells

Patrick H. Maxwell, Rayne Institute, UK
Cellular Oxygen Sensing - A Key Regulator of Angiogenesis

Sarah J. Childs, University of Calgary, Canada
Short Talk: Patterning Angiogenesis in the Zebrafish Embryo

08:00—11:00
The Matrix in Development
Meeting has ended...abstracts no longer viewable online.

Margaret Greenham Hall
* Elaine V. Fuchs, HHMI/Rockefeller University, USA
Beauty is Skin Deep: Differentiation and Development in the Skin

Robert Benezra, Memorial Sloan-Kettering Cancer Center, USA
The Id Proteins are Required for Tumor Angiogenesis

Mina J. Bissell, Lawrence Berkeley National Laboratory, USA
The Structural Basis of Tissue-Specific Signaling in Normal and Malignant Breast

09:20—09:40
Coffee Break

Eric Harvey Foyer
11:00—13:00
Poster Setup

Laslow Funtek 222-224
13:00—22:00
Poster Viewing

Laslow Funtek 222-224
16:30—17:00
Coffee & Snacks Available

Eric Harvey Foyer
17:00—19:00
Endothelial Specification: Arteries, Veins, Lymphatics
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
Jan K. Kitajewski, Columbia University, USA
Notch Function in Vascular Specification

* Harold F. Dvorak, Beth Israel Deaconess Medical Center, USA
Structure and Function of Cytokine Induced Vessels: Tumor Vessel Surrogates?

RĂ¼diger Klein, Max Planck Institute of Neurobiology, Germany
Requirements for Bi-Directional Eph/Ephrin Signaling in vivo

17:00—19:00
Matrix Structure and Assembly
Meeting has ended...abstracts no longer viewable online.

Margaret Greenham Hall
* Peter D. Yurchenco, UMDNJ RW Johnson Medical School, USA
Matrix Assembly, Regulatory and Survival Functions of Laminin and its Receptors in Embryonic Stem Cell Differentiation

Harold P. Erickson, Duke University Medical Center, USA
Stretching Fibronectin Matrix Fibrils and Single Molecules

Bianca Tomasini-Johansson, University of Wisconsin-Madison, USA
Cellular Control of Fibronectin Assembly

19:00—20:00
Welcome Mixer

Laslow Funtek 222-224
20:00—22:00
Poster Session 1

Laslow Funtek 222-224
20:00—22:00
Poster Session 1A: Angiogenesis and Vasculogenesis in Development

20:00—22:00
Poster Session 1B: Endothelial Progenitor Cells

20:00—22:00
Poster Session 1C: Lymphangiogenesis

20:00—22:00
Poster Session 1D: Angiopoietins, VEGFs, and Integrins

20:00—22:00
Poster Session 1E: Molecular Mechanisms of Angiogenesis

20:00—22:00
Poster Session 1F: Tissue-Specific Angiogenesis


SUNDAY, FEBRUARY 10

07:00—08:00
Breakfast

Donald Cameron Hall
08:00—11:00
Angiogenesis and Neurogenesis
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
Elizabeth Lindsay Illingsworth Baldini, Texas A&M Health Science Center, USA
Genetic Dissection of the Vascular Defects in DiGeorge Syndrome

* Peter F. Carmeliet, University of Leuven, VIB, Belgium
The VEGF Family: Angiogenesis and Beyond

Kari K. Alitalo, University of Helsinki, Finland
Lymphangiogenesis in Development and Diseases

Didier Stainier, Max Planck Institute for Heart and Lung Research, Germany
Function of VEGF-C in Angiogenesis, Organogenesis and Neurogenesis

08:00—11:00
Biological Consequences of Matrix Turnover
Meeting has ended...abstracts no longer viewable online.

Margaret Greenham Hall
Vito Quaranta, Vanderbilt University School of Medicine, USA
Laminin Processing by MMPs in Tumor Invasion Across Basement Membranes

Marsha A. Moses, Children's Hospital, USA
Matrix Metalloproteinases: Positive and Negative Regulators of Angiogenesis and Tumor Progression

Nathalie Ortega, University of California, San Francisco, USA
Biological Response to ECM Degradation: Insights from Endochondral Ossification and MMPs

* Raghu Kalluri, University of Texas MD Anderson Cancer Center, USA
Regulation of Angiogenesis by Vascular Basement Membrane

09:20—09:40
Coffee Break

Eric Harvey Foyer
11:00—13:00
Poster Setup

Laslow Funtek 222-224
13:00—22:00
Poster Viewing

Laslow Funtek 222-224
16:30—17:00
Coffee & Snacks Available

Eric Harvey Foyer
17:00—19:00
Angiogenesis and Endothelial Microenvironment (Joint). Session Sponsored by Cell Genesys, Inc.
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
* David A. Cheresh, University of California, San Diego, USA
Differential Raf-ERK Activation by Distinct Integrin/Growth Factor Receptor Pairs During Two Pathways of Angiogenesis: Therapeutic Implications

Rakesh K. Jain, Massachusetts General Hospital and Harvard Medical School, USA
Functional Heterogeneity in Blood and Lymphatic Vessels in Tumors: Insight from Intravital Microscopy

Erkki Ruoslahti, Sanford-Burnham Medical Research Institute, USA
Targeting the Endothelium

19:00—20:00
Welcome Mixer

Laslow Funtek 222-224
20:00—22:00
Poster Session 2

Laslow Funtek 222-224
20:00—22:00
Poster Session 2A: Regulation of Angiogenesis

20:00—22:00
Poster Session 2B: Basic Angiogenesis Mechanisms in Pathology

20:00—22:00
Poster Session 2C: Intracellular and Extracellular Mechanisms of Angiogenesis in Pathology

20:00—22:00
Poster Session 2D: Screening for Angiogenesis Modulators


MONDAY, FEBRUARY 11

07:00—08:00
Breakfast

Donald Cameron Hall
08:00—11:00
Matrix/Growth Factor Dependent Signaling (Joint)
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
* Martin Schwartz, Yale School of Medicine, USA
Integrins and Rho Family GTPases in Mechanotransduction

Anne J. Ridley, King's College London, UK
Rho GTPase Signaling in Endothelial Cells

Richard K. Assoian, University of Pennsylvania School of Medicine, USA
Defining the Requirement for Stress Fibers During G1 Phase Cell Cycle Progression

Tony Hunter, The Salk Institute for Biological Sciences, USA
Signaling by Tyrosine Phosphorylation

09:20—09:40
Coffee Break

Eric Harvey Foyer
11:00—13:00
Poster Setup

Laslow Funtek 222-224
13:00—22:00
Poster Viewing

Laslow Funtek 222-224
16:30—17:00
Coffee & Snacks Available

Eric Harvey Foyer
17:00—19:00
Tumor and Pathological Angiogenesis. Session Sponsored by Enzon, Inc.
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
Napoleone Ferrara, University of California, San Diego, USA
New Insights into the Regulation of Angiogenesis by VEGF

Richard O. Hynes, Massachusetts Institute of Technology, USA
Alpha-v Integrins as Negative Regulators of Angiogenesis

* Robert S. Kerbel, Sunnybrook Research Institute, Canada
Metronomic Antiangiogenic Chemotherapy: Genetic and Epigenetic Mechanisms Governing Longterm Response and Resistance

Dwayne G. Stupack, The Scripps Research Institute, USA
Short Talk: Intergrin-Mediated Death: Establishing a New Role for alphanu Intergrins in Angiogenesis

17:00—19:00
Mechanical and Cytoskeletal Responses
Meeting has ended...abstracts no longer viewable online.

Margaret Greenham Hall
* Keith W.T. Burridge, University of North Carolina at Chapel Hill, USA
Signaling from Adhesion to Rho Family GTPases

Paul A. Janmey, University of Pennsylvania, USA
The Cytoskeleton and Signal Transduction

Christopher S. Chen, Boston University, USA
Short Talk: New Microengineered Microenvironments to Study Cell Adhesion and Mechanics

Peter F. Davies, University of Pennsylvania, USA
Title to be Determined

19:00—20:00
Welcome Mixer

Laslow Funtek 222-224
20:00—22:00
Poster Session 3

Laslow Funtek 222-224
20:00—22:00
Poster Session 3A: Mechanisms of Angiogenic Inhibitors

20:00—22:00
Poster Session 3B: Gene, Liposome, and Antibody Treatment

20:00—22:00
Poster Session 3C: Intervention

20:00—22:00
Poster Session 3D: Angiogenesis in the Clinic: Monitoring Progression and Response


TUESDAY, FEBRUARY 12

07:00—08:00
Breakfast

Donald Cameron Hall
08:00—11:00
Structural Factors in Cell and Vessel Regulation (Joint)
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
* Donald E. Ingber, Wyss Institute for Biologically Inspired Engineering at Harvard, USA
Mechanochemical Signaling and Control of Angiogenesis

Donald M. McDonald, University of California, San Francisco, USA
Structural Heterogeneity of Angiogenic Blood Vessels

Michael P. Sheetz, Mechanobiology Institute, National University of Singapore, Singapore
Force-Dependent Signals in Cell Motility

Elisabetta Dejana, Uppsala University, Sweden
Role of Adherence Junctions in Endothelial Cell Proliferation and Angiogenesis

09:20—09:40
Coffee Break

Eric Harvey Foyer
16:30—17:00
Coffee & Snacks Available

Eric Harvey Foyer
17:00—19:00
Therapeutic Angiogenesis/Inhibition. Session Sponsored by the Juvenile Diabetes Research Foundation.
Meeting has ended...abstracts no longer viewable online.

Eric Harvey Theatre
Katherine W. Ferrara, University of California, Davis, USA
Imaging of Angiogenesis

Michael Simons, Yale University, USA
FGF Therapeutic Angiogenesis

* James M. Pluda, MedImmune, Inc., USA
Lessons from Anti-Angiogenesis Clinical Trials

17:00—19:00
Disruption of ECM Interactions: Therapeutic Implications
Meeting has ended...abstracts no longer viewable online.

Margaret Greenham Hall
* Judith A. Varner, University of California, San Diego, USA
Role of Fibronectin and its Receptors in Angiogenesis

Peter C. Brooks, New York University School of Medicine, USA
Cryptic ECM Elements and the Regulation of Angiogenesis and Tumor Invasion

Mark D. Bednarski, Targesome, Inc., USA
Integrin Targeted Nanoparticles for Imaging and Therapeutics

20:00—21:00
Welcome Mixer

Donald Cameron Hall
20:00—23:00
Entertainment

Donald Cameron Hall

WEDNESDAY, FEBRUARY 13

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 CA94244-01




We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676