Taos Convention Center (meeting only) Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2003



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Linking Innate with Adaptive Immune Responses (J4)


Organizer(s) Wayne M. Yokoyama and Albert S. Bendelac
January 30—February 4, 2003
Taos Convention Center (meeting only) • Taos, New Mexico USA
Abstract Deadline: Sep 30, 2002
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 2, 2002

Sponsored by DNAX Research, Inc. and The Director's Sponsor Fund


Summary of Meeting:
Recent advances indicate that the innate immune system not only controls the initial phases of host immune responses to pathogens but also plays a critical role in controlling and instructing adaptive immunity. This symposium will focus on the new frontiers of research on the cells, receptors, and signal transduction pathways that mediate innate immunity and control adaptive immunity.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


THURSDAY, JANUARY 30

15:00—19:00
Registration

Rio Grande Hall D
18:15—19:15
Welcome

Rio Grande Hall A-C
19:15—19:30
Orientation

Bataan
19:30—20:30
Keynote Address (Joint)
Meeting has ended...abstracts no longer viewable online.

Bataan
Jules A. Hoffmann, Institute of Cellular and Molecular Biology, France
Drosophila Host Defense: Innate Immunity in Drosophila


FRIDAY, JANUARY 31

07:00—08:00
Breakfast

Rio Grande Hall B-D
08:00—11:00
Receptors of Innate Immunity: Toll-Like Receptors (Joint)
Meeting has ended...abstracts no longer viewable online.

Bataan
Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA
Pattern Recognition Receptors of Innate Immunity

Alan Aderem, Center for Infectious Disease Research, USA
The Role of Toll-Like Receptors in Orchestrating the Innate Immune Response

* Alan Ezekowitz, Abide Therapeutics, USA
Pattern Recognition Receptors in Flies and Man

Ann Marshak-Rothstein, University of Massachusetts Medical School, USA
Chromatin, Toll-Like Receptor 9, and Systemic Autoimmune Disease

09:20—09:40
Coffee Break

Rio Grande Hall B-D
14:00—15:00
Poster Setup

Bataan
15:00—22:00
Poster Viewing

Bataan
14:30—16:30
Workshop 1: Innate Receptors, Signaling and Cell Death

Rio Grande Hall A-B
* Glenn K. Matsushima, University of North Carolina at Chapel Hill, USA
Novel Receptors in the Clearance of Apoptotic Cells

* Julie Djeu, Moffitt Cancer Center, USA

Michael R. Daws, University of California, San Francisco, USA
Pattern Recognition by TREM-2: Binding of Anionic Ligands

Hong Zhang, University of California, San Francisco, USA
Regulation of Leukocyte Chemokine Signaling by Src-Family Kinase and the Inhibitory Receptor PIR-B

Ross M. Kedl, University of Colorado Denver, USA
A TLR7 Agonist Selectively Induces IL-12 and TNFalpha Production in CD8-CD11b+CD11c+ Dendritic Cells

Arya Biragyn, NIA, National Institutes of Health, USA
Many Faces of Beta-Defensin: Activation of DC Maturation via TLR-4

Koichi Kobayashi, Yale University School of Medicine, USA
Negative Regulation of the Toll-Like Receptor System

Hidenori Ichijo, University of Tokyo, Japan
Roles of ASK1-p38 MAPK Cascade in Mammalian Innate Immunity

Heather M. Seitz, Pfizer Inc., USA
Relationship of Novel Receptor Tyrosine Kinases in Phagocytosis of Apoptotic Cells

Fabio Martinon, Harvard School of Public Health, USA
The Inflammasome: A Molecular Platform Triggering Activation of the Inflammatory Caspases and Processing of proIL-1beta

14:30—16:30
Workshop 1: Signaling in Macrophages and Dendritic Cells

Rio Grande Hall C-D
* Pamela A. Hankey, Pennsylvania State University, USA
The STK Receptor Tyrosine Kinase Regulates the Response of Macrophages to Cytokine/LPS Stimulation and the Balance between Classical vs. Alternative Activation

Katherine C. Brittingham, US Army Medical Research Institute of Infectious Diseases, USA
Regulation of Macrophage Function by the Adipocyte Fatty Acid Binding Protein, aP2

Satoshi Uematsu, Research Institute for Microbial Diseases, Japan
Gene Regulation and in vivo Role of Membrane Bound PGE2 Synthase

Jeffrey L. Curtis, University of Michigan, USA
Phospholipase C gamma2 (PLC gamma2) Occupies a Central Signaling Role during Phagocytosis of Apoptotic Cells by Mouse Macrophages

Michael J. Rauh, BC Cancer Research Centre, Canada
SHIP-Deficiency Leads to Anti-Inflammatory Macrophage Programming

16:30—17:00
Coffee & Snacks Available

Bataan
17:00—19:00
Apoptosis and Innate Immunity
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall A-B
Glenn K. Matsushima, University of North Carolina at Chapel Hill, USA
Novel Receptors in the Clearance of Apoptotic Cells

* Averil I. Ma, University of California, San Francisco, USA
A20 and Innate Immune Responses

Jeffrey C. Rathmell, Vanderbilt University, USA
Glucose Metabolism and Apoptosis

17:00—19:00
The Regulation of Cytokine Production in Leukocytes
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
* Stephen T. Smale, University of California, Los Angeles, USA
Selective Activation of Cytokine Genes in Macrophages: Roles of Rel Proteins and Nucleosome Remodeling Complexes

Giorgio Trinchieri, NCI, National Institutes of Health, USA
The Regulation of IL-12 Production

Alberto Mantovani, Humanitas University, Italy
The Long Pentraxin PTX3: Non-Redundant Role in Innate Immunity and More

19:00—20:00
Social Hour

Bataan
20:00—22:00
Poster Session 1: Innate Receptors, Signaling and Cell Death

Bataan

SATURDAY, FEBRUARY 1

07:00—08:00
Breakfast

Bataan
08:00—11:00
Model Systems of Innate Immunity
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall A-B
Jeffery L. Dangl, University of North Carolina at Chapel Hill, USA
The Plant Immune System—Ancient Immunity While Standing Still

Elena A. Levashina, Max Planck Institute for Infection Biology, Germany
Thioester-Containing Proteins in Immune Defense of Mosquitoes

Frederick M. Ausubel, Massachusetts General Hospital, USA
The C. elegans Immune Defense Response

* Alan Sher, NIAID, National Institutes of Health, USA
Innate Recognition of Toxoplasma gondii by Dendritic Cells

08:00—11:00
Modulation of Immune Responses by Antigen Presenting Cells
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
Anne O'Garra, Francis Crick Institute, UK
Flexibility of Mouse Classical and Plasmacytoid-Derived Dendritic Cells in Directing Th1 and Th2 Cell Development: Dependency on Antigen Dose and Differential Toll-Like Receptor Ligation

* David M. Mosser, University of Maryland, USA
Biasing T Cell Responses by Modulating APC Cytokines

Judith E. Allen, University of Manchester, UK
Th2 Cytokines and Macrophage Function in vivo

Peter M. Henson, National Jewish Health Center and University of Colorado Denver, USA
Why Eating Dying Cells Does a Body Good: Anti-Inflammatory Responses to Apoptotic Cells

09:20—09:40
Coffee Break

Bataan
11:00—13:00
Poster Setup

Bataan
13:00—22:00
Poster Viewing

Bataan
14:30—16:30
Workshop 2: Innate Control of Infections

Rio Grande Hall A-B
* Christine A. Biron, Brown University, USA

* Alan Sher, NIAID, National Institutes of Health, USA

Stephanie Blandin, European Molecular Biology Laboratory, Germany
Functional Analysis of Immune Genes in the Mosquito, Anopheles gambiae

Sara R. Cherry, University of Pennsylvania School of Medicine, USA
Susceptibility to Infection is Sensitive to Modulation of the Endocytic Machinery in a Drosophila Model for Viral Pathogenesis

Thomas R. Hawn, University of Washington, USA
A Polymorphism in Human Toll-Like Receptor 5 Encodes a Variant that Abolishes Flagellin Signaling

Lena Alexopoulou, Center of Immunology Marseille-Luminy, France
Hyporesponsiveness to Vaccination with Borrelia burgdorferi Outer Surface Protein A (OspA) in Humans and TLR1-Deficient Mice

Daniela I. Verthelyi, U.S. Food and Drug Administration, USA
CpG ODN Act as Vaccine Adjuvants and Immunoprotective Agents in Healthy and Immunocompromised Primates

Rachelle Salomon, St. Jude Children's Research Hospital, USA
Characterization of the Biochemical Pathways Used by Type I Interferon to Signal for Immunoregulation

Brigitte G. Dorner, Washington University School of Medicine, USA
Coordinate Expression of Type 1 Cytokines by Natural Killer Cells during Murine Cytomegalovirus Infection

Mark T. Orr, Infectious Disease Research Institute, USA
Altered Immune Responses and Pathogenesis of Recombinant Herpes Simplex Virus with the Restored Ability to Down-Regulate MHC Class I in Mice

14:30—16:30
Workshop 2: Host Defense to Microbial Pathogens

Rio Grande Hall C-D
* Christian M. Bogdan, FAU Erlangen-Nürnberg, University Hospital Erlangen, Germany
The Role of NOS, NADPH oxidase and Type I Interferons in the Defense against Microbial Pathogens

Teunis B.H. Geijtenbeek, University of Amsterdam, Netherlands
Pathogens Target DC-Sign to Affect Immune Responses: Immune Escape Mechanisms

Carrie M. Rosenberger, Genentech, Inc., USA
Macrophage Signal Transduction Culminates in Elastase-Mediated Impairment of Intracellular Salmonella Typhimurium Replication

DeLisa Fairweather, Johns Hopkins University, USA
IL-12Rbeta1 and TLR4 Signaling Increase IL-1beta and IL-18-Associated Myocarditis and Coxsackievirus Replication

Shuangping Shi, Cornell University Weill Medical College, USA
Genomic Approaches to Understand How the Macrophage Responds to Mycobacterium tuberculosis

16:30—17:00
Coffee & Snacks Available

Bataan
17:00—19:00
NK Cells in Innate Immunity
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall A-B
Christine A. Biron, Brown University, USA
Cytokine Interactions in Innate Responses to Viral Infections

* Wayne M. Yokoyama, Washington University School of Medicine, USA
Specific Natural Killer Cell Responses to Viral Infection

Julie Djeu, Moffitt Cancer Center, USA
Signal Transduction Controlling Lytic Function in Natural Killer Cells

Eric O. Long, NIAID, National Institutes of Health, USA
Short Talk: The Vav1 - Rac1 Pathway is Central to Activation and Inhibition of NK Cell Cytotoxicity

17:00—19:00
Macrophage-Mediated Pathogenesis - Infectious Etiologies
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
* Christopher L. Karp, Bill & Melinda Gates Foundation, USA

Daniel J. Cua, Merck Research Laboratories, USA
Differential Roles of IL-23 and IL-12 in Host Defense and Autoimmune Inflammation

Steven L. Kunkel, University of Michigan Medical School, USA
The Central Role of Chemokines in Linking Innate and Adaptive Immunity

Frank Brombacher, International Center for Genetic Engineering and Biotechnology, South Africa
The Role of Alternatively Activated Macrophages in Infectious Diseases: Studies in Macrophage-Specific IL-4 Receptor-alpha Deficient Mice

19:00—20:00
Social Hour

Bataan
20:00—22:00
Poster Session 2: Innate Control of Infections

Bataan

SUNDAY, FEBRUARY 2

07:00—08:00
Breakfast

Rio Grande Hall B-D
08:00—11:00
Innate Control of Intracellular Infections (Joint)
Meeting has ended...abstracts no longer viewable online.

Bataan
Michel Desjardins, University of Montreal, Canada
Phagocytosis in the Post-Genomic Era

* Emil R. Unanue, Washington University School of Medicine, USA
Stages in the Control of Listeria Infection

Daniel A. Portnoy, University of California, Berkeley, USA
Why Listeria Monocytogenes is an Intracellular Pathogen

David L. Sacks, NIAID, National Institutes of Health, USA
How Do Dendritic Cells Process Leishmania Antigens for Cross-Presentation to CD8+ T Cells?

09:20—09:40
Coffee Break

Rio Grande Hall B-D
14:00—15:00
Poster Setup

Bataan
15:00—22:00
Poster Viewing

Bataan
14:30—16:30
Workshop 3: Modulation of Adaptive Immunity by the Innate Immune System

Rio Grande Hall A-B
* Albert S. Bendelac, University of Chicago, USA

* Veronika Groh-Spies, Fred Hutchinson Cancer Research Center, USA

Bali Pulendran, Stanford University School of Medicine, USA
Different TLR Agonists Condition Dendritic Cells to Induce Distinct Classes of Immune Responses in vitro and in vivo

Laure Perrin-Cocon, Institut National de la Santé et de la Recherche Médicale, France
Lysophosphatidylcholine: An Endogenous Signal of Danger Promoting Mature Dendritic Cell Generation

Annie L. Neild, Yale University, USA
Legionella Reveal Novel Dendritic Cell Functions that Facilitate Selection of Antigens for MHC Class II Presentation

Rima Koka, University of Chicago, USA
Role of IL15Ralpha in the Peripheral Maintenance of NK Cells

Sigrid P. Dubois, National Cancer Institute, National Institutes of Health, USA
Recycling and Trans-Presentation of IL-15 by IL-15Ralpha

Arin Betchen, University of California, San Francisco, USA
Immunologic Regulation of Airway Remodeling in Response to Chronic Infection with Mycoplasma pulmonis

Joseph D. Miller, Emory University, USA
CD/94/NKG2 Expression Does Not Inhibit Cytotoxic Function of Lymphocytic Choriomeningitis Virus-Specific CD8+ T Cells

Jin Seon S. Im, MD Anderson Cancer Center, USA
CD1d Dependent Activation of NK T Cells by Schwann Cells: Implications for Leprosy and Peripheral Neuropathy

14:30—16:30
Workshop 3: Innate and Adaptive Immune Responses

Rio Grande Hall C-D
* Evelyn A. Kurt-Jones, University of Massachusetts Medical School, USA
Role of Toll-Like Receptor 2 (TLR2) and CD14 in the Innate Immune Response to Bacteria and Viruses

Maria C. Jenmalm, DNAX Research Inc., USA
Regulation of Myeloid Cell Function through the CD200 Receptor

Matthias Hesse, Cornell University College of Veterinary Medicine, USA
Macrophage-Derived IL-10 Fails to Protect in Murine Schistosomiasis

Thomas J. Murphy, , Ireland
Enhanced TLR Reactivity After Injury is Associated with Increased Mortality to a TLR4 Agonist

Dermot P. B. McGovern, Cedars-Sinai Medical Center, USA
Innate Immunogenetics and Inflammatory Bowel Disease (IBD)

16:30—17:00
Coffee & Snacks Available

Bataan
17:00—19:00
The Interplay Between Innate and Adaptive Immunity I
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall A-B
Polly Matzinger, NIAID, National Institutes of Health, USA
Conversations for Class Control

* Albert S. Bendelac, University of Chicago, USA
Developmental Pathways of Innate-Like NKT Lymphocytes

Marco Colonna, Washington University School of Medicine, USA
A Role for TREM Receptors in Myeloid Cell Development

Bali Pulendran, Stanford University School of Medicine, USA
Short Talk: Impairment of Dendritic Cells and Adaptive Immunity by Anthrax Toxin, Lethal Factor

17:00—19:00
Pathogen Regulation of Macrophage Functions
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
* Joel D. Ernst, New York University School of Medicine, USA
M. tuberculosis and Innate Inhibition of Adaptive Effector Responses

Christopher A. Hunter, University of Pennsylvania, USA
NF-kappaB: Master of danger?

Hidde L. Ploegh, Boston Children's Hospital, USA
Viral Inhibition of Antigen Presentation

19:00—20:00
Social Hour

Bataan
20:00—22:00
Poster Session 3: Modulation of Adaptive Immunity by the Innate Immune System

Bataan

MONDAY, FEBRUARY 3

07:00—08:00
Breakfast

Bataan
08:00—11:00
The Interplay Between Innate and Adaptive Immunity II
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall A-B
Veronika Groh-Spies, Fred Hutchinson Cancer Research Center, USA
Significance of the NKG2D Receptor and its Tumor-Associated Ligands

David H. Raulet, University of California, Berkeley, USA
Innate and Adaptive Immunity to Tumor Cells

* Philippa C. Marrack, HHMI/National Jewish Health, USA
Innate Immune Maintenance of T Helper Cells

Charles D. Surh, La Jolla Institute for Allergy and Immunology, USA
Homeostasis of Memory CD8+ T Cells Influenced by the Innate Immune System

08:00—11:00
Macrophage Development and Differentiation
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
Harinder Singh, Cincinnati Children's Hospital Medical Center, USA
PU.1 and the Transcriptional Regulation of Macrophage Differentiation

* Siamon Gordon, Chang Gung University / University of Oxford, UK
Macrophage Receptors for Adhesion and Phagocytosis

Peter J. Murray, St. Jude Children's Research Hospital, USA
Regulation of Macrophage Function by IL-10

Sabine Ehrt, Weill Cornell Medical College, USA
Transcriptional Responses of Mycobacterium tuberculosis Infected Macrophages: Roles of IFNgamma, iNOS, phox and MyD88

09:20—09:40
Coffee Break

Bataan
16:30—17:00
Coffee & Snacks Available

Bataan
17:00—19:00
Innate Immunity in Human Disease Pathogenesis
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall A-B
* Jean-Laurent Casanova, Rockefeller University, USA
Genetic Dissection of Immunity to Infection: The Human Model

Foo Y. Liew, University of Glasgow, UK
The Role of Innate Cytokines in Inflammatory Arthritis

Gabriel Nuñez, University of Michigan, USA
NOD2 and Crohn's Disease

17:00—19:00
Macrophage Pathologies, Non-Infectious Etiologies
Meeting has ended...abstracts no longer viewable online.

Rio Grande Hall C-D
Gregory A. Grabowski, Synageva BioPharma, USA
Lysosomal Storage Diseases and Macrophage Malfunction

Ajay Chawla, University of California, San Francisco, USA
PPARs, Macrophage Functions and Atherosclerosis

Ira Tabas, Columbia University, USA
The Pathobiology of the Cholesterol-Loaded Macrophage: How Induction of Apoptosis and ER Stress Pathways Become a Matter of Life and Death

19:00—20:00
Social Hour

Bataan
20:00—23:00
Entertainment

Bataan

TUESDAY, FEBRUARY 4

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 AI053503-01




We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676