Fairmont Banff Springs Floorplan

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This meeting took place in 2003



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Molecular Mechanisms of Apoptosis (B6)


Organizer(s) Stephen W. Fesik, Xiaodong Wang, Craig B. Thompson
February 8—13, 2003
Fairmont Banff Springs • Banff, Alberta Canada
Abstract Deadline: Oct 8, 2002
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 9, 2002

Sponsored by Novartis Pharmaceuticals Corporation and The Director's Sponsor Fund

Summary of Meeting:
Apoptosis is an important process for the removal of damaged or unwanted cells and when dysregulated can lead to several diseases. Recently, much has been learned about the biochemical pathways involved in programmed cell death as well as the three-dimensional structures of the proteins in these signaling pathways. In addition, data are emerging on how apoptosis is triggered and how late stage events in apoptosis are carried out. However, it will be important to learn how to utilize this information to better understand the role of apoptosis in disease and how to develop therapeutic agents to treat diseases caused by abberent cell death. In this Keystone Symposium, new biochemical pathways, three-dimensional structures, and information on early and late stage events in apoptosis will be discussed. The contribution of programmed cell death to disease and therapeutic approaches for treating these disorders will also be covered.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SATURDAY, FEBRUARY 8

15:00—19:00
Registration

Van Horne Foyer
18:15—19:15
Welcome

Van Horne Foyer
19:15—19:30
Orientation

Van Horne Ballroom AB
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
Shigekazu Nagata, IFReC, Osaka University, Japan
Breakdown of Chromosomal DNA during Apoptosis


SUNDAY, FEBRUARY 9

07:00—08:00
Breakfast

Riverview/Cascade/Conservatory
08:00—11:00
Identification of New Apoptotic Genes
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
Karen H. Vousden, Crick Institute, UK
Regulation of Cell Growth and Death by p53

Ding Xue, University of Colorado, USA
The Regulation and Execution of Apoptosis in C. elegans

John M. Abrams, University of Texas Southwestern Medical Center, USA
Molecular Genetics of Programmed and Unprogrammed Cell Death in Drosophila

* John C. Reed, F. Hoffmann-La Roche AG, Switzerland
Mechanisms and Modulators of Iap-Family Apoptosis Suppressors

09:20—09:40
Coffee Break

Van Horne Foyer
11:00—13:00
Poster Setup

Alberta/New Brunswick
13:00—22:00
Poster Viewing

Alberta/New Brunswick
16:30—17:00
Coffee & Snacks Available

Van Horne Foyer
17:00—19:00
Biochemical Pathways
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
* Xiaodong Wang, BeiGene, China
Biochemical Studies of Apoptosis

Richard J. Youle, NINDS, National Institutes of Health, USA
The Mechanism and Consequences of Bax Translocation to Mitochondria

Marcus E. Peter, University of Chicago, USA
CD95 Type I and Type II Cells

19:00—20:00
Social Hour

Alberta/New Brunswick
20:00—22:00
Poster Session 1

Alberta/New Brunswick

MONDAY, FEBRUARY 10

07:00—08:00
Breakfast

Riverview/Cascade/Conservatory
08:00—11:00
Initiation of Apoptosis
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia
BH3 Only Pro-Apoptotic Bcl-2 Family Members and More

* Junying Yuan, Harvard Medical School, USA
Pivotal Role of Oligomerization in Expanded Polyglutamine Neurodegeneration Disorders

Valter D. Longo, University of Southern California, USA
Regulation of Longevity and Stress Resistance in S. cerevisiae. Is Death Programmed?

John L. Cleveland, The Scripps Research Institute, USA
Pathways Regulating Apoptosis in Hematopoiesis and Cancer

09:20—09:40
Coffee Break

Van Horne Foyer
11:00—13:00
Poster Setup

Alberta/New Brunswick
13:00—22:00
Poster Viewing

Alberta/New Brunswick
16:30—17:00
Coffee & Snacks Available

Van Horne Foyer
17:00—19:00
Clearance Mechanisms
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
Kodi S. Ravichandran, University of Virginia, USA
Signaling to Engulfment - The Beginnings of a Good Meal

Zheng Zhou, Baylor College of Medicine, USA
The Genetics of Hiding the Corpse

* Philippe Chavrier, Laboratoire de la Dynamique du Cytosquelette, France
Function of the Small GTP-Binding Protein ARF6 in Membrane Dynamics during Phagocytosis

19:00—20:00
Social Hour

Alberta/New Brunswick
20:00—22:00
Poster Session 2

Alberta/New Brunswick

TUESDAY, FEBRUARY 11

07:00—08:00
Breakfast

Rview/Oval/Cas/Cons
08:00—11:00
Apoptosis in Disease
Meeting has ended...abstracts no longer viewable online.

Van Honre Ballroom AB
Jennifer M. Puck, National Institutes of Health, USA
Autoimmune Lymphoproliferative Syndrome: What Underlies the Variations in Phenotype

Richard N. Kitsis, Albert Einstein College of Medicine, USA
Manipulating Apoptosis in Heart Disease

* Stanley J. Korsmeyer, Harvard University, USA
Dysregulation of Apoptotic Signaling Pathways Leading to Tumorigenesis

Martin C. Raff, University College London, UK
Self-Destruct Programs in Neurons

09:20—09:40
Coffee Break

Van Horne Foyer
11:00—13:00
Poster Setup

Alberta/New Brunswick
13:00—22:00
Poster Viewing

Alberta/New Brunswick
16:30—17:00
Coffee & Snacks Available

Van Horne Foyer
17:00—19:00
Therapeutic Applications
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
* Donald W. Nicholson, Nimbus Discovery, Inc., USA
Caspase Modulation

Saul H. Rosenberg, Abbott Laboratories, USA
Small Molecular Inhibitors of Bcl-2 Family Proteins for the Treatment of Cancer

Vishva M. Dixit, Genentech, USA
New Players in an Old Field - Novel TNF Family Members

19:00—20:00
Social Hour

Alberta/New Brunswick
20:00—22:00
Poster Session 3

Alberta/New Brunswick

WEDNESDAY, FEBRUARY 12

07:00—08:00
Breakfast

Riverview/Cascade/Conservatory
08:00—11:00
Structural Biology
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
Martin Renatus, Novartis Pharma AG, Switzerland
Structure Basis for Caspase Activation and Regulation

* Yigong Shi, Tsinghua University School of Medicine, China
A Conserved Mechanism of Caspase Activation

Gerhard Wagner, Harvard Medical School, USA
Structures of Proteins Involved in Signaling of Apoptosis

Nico Tjandra, National Institutes of Health, USA
NMR Study of Bax

09:20—09:40
Coffee Break

Van Horne Foyer
16:30—17:00
Coffee & Snacks Available

Van Horne Foyer
17:00—19:00
Late Breaking Developments
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
* Jürg Tschopp, University of Lausanne, Switzerland
Activation of Pro-Inflammatory Caspases by NALP Family Members

Jennifer A. Straub, University of Rochester, USA
Short Talk: A Role for Prolyl Hydroxylation in Trophic Factor Deprivation-Induced Neuronal Cell Death

Kejie Yin, Washington University School of Medicine, USA
Short Talk: ABeta-Induced Cell Death Involves smac Release and Endonuclease G Translocation from Mitochondria via Inhibition of Akt Activity in Cerebrovascular Endothelial Cells

Yihru Fannjiang, Johns Hopkins University, USA
Short Talk: The Role of Yar-1 in Saccharomyces cerevisiae Programmed Cell Death

19:15—20:15
Social Hour

Alberta/New Brunswick
20:15—23:15
Entertainment

Alberta/New Brunswick

THURSDAY, FEBRUARY 13

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge additional support for this conference from:


Cell Signaling Technology, Inc.

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