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This meeting took place in 2003
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
Cell Biology of the Immune Response (J8)
Organizer(s) Ira Mellman, Richard Flavell and Ralph M. Steinman
March 5—10, 2003
Keystone Resort • Keystone, Colorado USA
Abstract Deadline: Nov 5, 2002
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 6, 2003
Supported by Keystone Symposia
Summary of Meeting:
The past 10-15 years have been marked by spectacular progress towards understanding the mechanisms of the immune response. At the same time, there have also been great strides made towards understanding the cell biological principles governing the behavior of all cells, including those of the immune system. Only recently, however, has attention been turned towards a systematic application of emerging principles in cell biology to considerations of the immune response. Such attention has already begun to provide important new concepts in areas as diverse as signal transduction, cell-cell interaction, lymphocyte development, antigen processing, and transcriptional regulation. The major goal of the proposed meeting is to further this emergent interface by bringing together investigators, postdoctoral fellows, and students from the broad range of the immunological community in a form with leading cell biologists representing a number of the most important and relevant areas of cell biology.
View Scholarships/Awards
The past 10-15 years have been marked by spectacular progress towards understanding the mechanisms of the immune response. At the same time, there have also been great strides made towards understanding the cell biological principles governing the behavior of all cells, including those of the immune system. Only recently, however, has attention been turned towards a systematic application of emerging principles in cell biology to considerations of the immune response. Such attention has already begun to provide important new concepts in areas as diverse as signal transduction, cell-cell interaction, lymphocyte development, antigen processing, and transcriptional regulation. The major goal of the proposed meeting is to further this emergent interface by bringing together investigators, postdoctoral fellows, and students from the broad range of the immunological community in a form with leading cell biologists representing a number of the most important and relevant areas of cell biology.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
TUESDAY, MARCH 4
WEDNESDAY, MARCH 5
THURSDAY, MARCH 6
FRIDAY, MARCH 7
SATURDAY, MARCH 8
SUNDAY, MARCH 9
MONDAY, MARCH 10
Conference Program Print | View meeting in 12 hr (am/pm) time
TUESDAY, MARCH 4
08:00—11:00
Dendritic Cells and the Control of Immunity vs. Tolerance
Meeting has ended...abstracts no longer viewable online.
Yong-Jun Liu,
Sanofi, USA
Human Epithelial Cells Trigger Dendritic Cell-Mediated Allergic Inflammation by Producing TSLP
Human Epithelial Cells Trigger Dendritic Cell-Mediated Allergic Inflammation by Producing TSLP
Kayo Inaba,
Kyoto University, Japan
Peripheral Tolerance via DCs in vivo
Peripheral Tolerance via DCs in vivo
Maria Grazia Roncarolo,
Stanford University School of Medicine, USA
Role of Regulatory T Cells in Immunological Tolerance
Role of Regulatory T Cells in Immunological Tolerance
*
Anne O'Garra,
Francis Crick Institute, UK
Flexibility of Mouse Classical and Plasmacytoid-Derived Dendritic Cells in Directing Th1 and Th2 Cell Development: Dependency on Antigen Dose and Differential Toll-Like Receptor Ligation
Flexibility of Mouse Classical and Plasmacytoid-Derived Dendritic Cells in Directing Th1 and Th2 Cell Development: Dependency on Antigen Dose and Differential Toll-Like Receptor Ligation
14:00—16:30
Workshop 1: Immunity and Tolerance to Tumors
*
Olivera J. Finn,
University of Pittsburgh School of Medicine, USA
Shu-Hsia Chen,
Mount Sinai School of Medicine, USA
Regulation of Dendritic Cell Function by NK Cells: Mechanisms Underlying the Synergism between IL-12 and 4-1 BB Activation
Regulation of Dendritic Cell Function by NK Cells: Mechanisms Underlying the Synergism between IL-12 and 4-1 BB Activation
Michael D. Gunn,
Duke University Medical Center, USA
Splenic Immature PDC Induce the Development of IL-10 Producing CD4+ T Regulatory Cells
Splenic Immature PDC Induce the Development of IL-10 Producing CD4+ T Regulatory Cells
Michael R. Shurin,
University of Pittsburgh, USA
Small Rho GTPases Regulate Dendropoiesis in Cancer
Small Rho GTPases Regulate Dendropoiesis in Cancer
Sally Ann Litherland,
Florida Hospital Cancer Institute, USA
STAT5 Dysfunction in Autoimmune Myeloid Antigen Presenting Cell Activation and Differentiation
STAT5 Dysfunction in Autoimmune Myeloid Antigen Presenting Cell Activation and Differentiation
Mariolina Salio,
Weatherall Institute of Molecular Medicine, UK
Efficacy of Murine Myeloid and Plasmacytoid Dendritic Cells in Eliciting Adaptive Immune Responses
Efficacy of Murine Myeloid and Plasmacytoid Dendritic Cells in Eliciting Adaptive Immune Responses
Heather Zwickey,
National College of Naturopathic Medicine, USA
DCs Presenting Self Antigens: Tolerance or Activation?
DCs Presenting Self Antigens: Tolerance or Activation?
Mohamad Mohty,
CHU de Nantes/INSERM U892, France
Interferon-Alpha Skews Monocyte Differentiation into Toll-like Receptor 7 Expressing Dendritic Cells with Potent Functional Activities
Interferon-Alpha Skews Monocyte Differentiation into Toll-like Receptor 7 Expressing Dendritic Cells with Potent Functional Activities
Hubert Eng,
Virexx Inc., Canada
Complexation with Murine MAb-B43.13 Alters the Endocytic Trafficking of the Mucinous Tumor Antigen CA125 after Uptake by Human Dendritic Cells
Complexation with Murine MAb-B43.13 Alters the Endocytic Trafficking of the Mucinous Tumor Antigen CA125 after Uptake by Human Dendritic Cells
Alexandra M. Livingstone,
University of Rochester Medical Center, USA
Helper-Dependent CD8+ T Cell Memory Requires CD40 Expression on the Immunizing Dendritic Cell, but Not on CD4+ or CD8+ T Cells.
Helper-Dependent CD8+ T Cell Memory Requires CD40 Expression on the Immunizing Dendritic Cell, but Not on CD4+ or CD8+ T Cells.
17:00—19:00
Dendritic Cell Maturation in vivo
Meeting has ended...abstracts no longer viewable online.
*
Anne O'Garra,
Francis Crick Institute, UK
David F. Tough,
Edward Jenner Institute for Vaccine Research, UK
Regulation of Immune Responses by Type I Interferon
Regulation of Immune Responses by Type I Interferon
A. Karolina Palucka,
Tha Jackson Laboratory for Genomic Medicine, USA
Dendritic Cells as Melanoma Vaccines
Dendritic Cells as Melanoma Vaccines
Masaru Taniguchi,
RIKEN RCAI, Japan
Regulatory Interaction between Valpha14 NKT Cells and Dendritic Cells
Regulatory Interaction between Valpha14 NKT Cells and Dendritic Cells
08:00—11:00
Antigen Capture by DC in situ
Meeting has ended...abstracts no longer viewable online.
*
Jacques F. Banchereau,
The Jackson Laboratory for Genomic Medicine, USA
Michel C. Nussenzweig,
HHMI/Rockefeller University, USA
Targeting Antigens to Lymphoid Tissue DCs
Targeting Antigens to Lymphoid Tissue DCs
Marc K. Jenkins,
University of Minnesota Medical School, USA
In Vivo Analysis of Antigen-Presentation to CD4 T Cells
In Vivo Analysis of Antigen-Presentation to CD4 T Cells
Giorgio Trinchieri,
NCI, National Institutes of Health, USA
Physiology of Mouse Interferon Producing Cells
Physiology of Mouse Interferon Producing Cells
Akiko Iwasaki,
HHMI/Yale University School of Medicine, USA
Short Talk: Primary Role of Vaginal Dendritic Cells in Th1 Induction during Genital Herpes Simplex Virus-2 Infection
Short Talk: Primary Role of Vaginal Dendritic Cells in Th1 Induction during Genital Herpes Simplex Virus-2 Infection
14:00—16:30
Workshop 2: DC Capture of Antigens and Pathogens
*
Paola Ricciardi-Castagnoli,
Toscana Life Science Foundation, Italy
*
Alan Sher,
NIAID, National Institutes of Health, USA
Li-Yun Coty Huang,
U.S. Food and Drug Administration, USA
Brucella abortus Activates Dendritic Cells and Splenocytes to Secrete IL-12p40 and TNFalpha via Different Toll-Like Receptors
Brucella abortus Activates Dendritic Cells and Splenocytes to Secrete IL-12p40 and TNFalpha via Different Toll-Like Receptors
Marina N. Fleeton,
National Institutes of Health, USA
CD11blo/CD8alpha- Peyer’s Patch Dendritic Cells Process Epithelial Cell-Associated Viral Antigens following Infection with Reovirus, Type 1 Lang
CD11blo/CD8alpha- Peyer’s Patch Dendritic Cells Process Epithelial Cell-Associated Viral Antigens following Infection with Reovirus, Type 1 Lang
Amy C. Herring,
University of Michigan, USA
The Role of Pulmonary Dendritic Cells in the Developing T1 Response to Cryptococcus neoformans Infection
The Role of Pulmonary Dendritic Cells in the Developing T1 Response to Cryptococcus neoformans Infection
W. L. William Chang,
University of California, Davis, USA
Alteration of Dendritic Cell Maturation and Functions by Cytomegalovirus-Encoded Interleukin-10
Alteration of Dendritic Cell Maturation and Functions by Cytomegalovirus-Encoded Interleukin-10
Christopher M. Smith,
Walter and Eliza Hall Institute of Medical Research, Australia
Conventional CD8a+ Dendritic Cells Prime CTL Immunity to Cutaneous Herpes Simplex Virus-1 Infection
Conventional CD8a+ Dendritic Cells Prime CTL Immunity to Cutaneous Herpes Simplex Virus-1 Infection
Gabriele Pollara,
University College London, UK
Dendritic Cell Innate Responses to HSV Infection
Dendritic Cell Innate Responses to HSV Infection
Kevin L. Legge,
University of Iowa Carver College of Medicine, USA
Respiratory Dendritic Cell Trafficking to the Regional Lymph Nodes is Limited to the Early Stage of Experimental Influenza Infection
Respiratory Dendritic Cell Trafficking to the Regional Lymph Nodes is Limited to the Early Stage of Experimental Influenza Infection
Maria Rescigno,
European Institute of Oncology, Italy
Bacteria Impede the Migratory Clearance and the Differentiation of Monocytes into Dendritic Cells to Lymph Nodes and Thereby Limit the Development of Adaptive Immune Responses
Bacteria Impede the Migratory Clearance and the Differentiation of Monocytes into Dendritic Cells to Lymph Nodes and Thereby Limit the Development of Adaptive Immune Responses
Leopoldo Flores-Romo,
El Centro de Investigación y de Estudios Avanzados del IPN, Mexico
Cutaneous Langerhans Dendritic Cells in a Murine Model of Leprosy: in vivo Analysis
Cutaneous Langerhans Dendritic Cells in a Murine Model of Leprosy: in vivo Analysis
Anne Hosmalin,
Institut Cochin, INSERM 1016, Université Paris Descartes, France
Processing of an HIV-1 Immunodominant Restricted Epitope by the Cytosolic Protease TPPII
Processing of an HIV-1 Immunodominant Restricted Epitope by the Cytosolic Protease TPPII
17:00—19:00
Exogenous Pathway and Cross-Presentation
Meeting has ended...abstracts no longer viewable online.
*
Jacques F. Banchereau,
The Jackson Laboratory for Genomic Medicine, USA
Sebastian Amigorena,
Institut Curie, France
Exogenous Pathway via Fc Receptors
Exogenous Pathway via Fc Receptors
Michael J. Bevan,
HHMI/University of Washington, USA
Maintaining memory
Maintaining memory
Philippe D. Pierre,
Centre d'Immunologie Marseille-Luminy, CIML, France
Aggregation in Maturing DCs, A Mean to Segregate Self Antigens from the Proteasome
Aggregation in Maturing DCs, A Mean to Segregate Self Antigens from the Proteasome
Carl G. Figdor,
Radboud University Medical Center, Netherlands
Short Talk: The C-Type Lectin DC-SIGN (CD209) is an Antigen Uptake Receptor for Candida albicans on Dendritic Cells
Short Talk: The C-Type Lectin DC-SIGN (CD209) is an Antigen Uptake Receptor for Candida albicans on Dendritic Cells
Stefan Freigang,
University Hospital Zurich, Switzerland
Short Talk: Endogenous Neosynthesis Versus Cross-Presentation of Polioviral Antigen for CTL Priming
Short Talk: Endogenous Neosynthesis Versus Cross-Presentation of Polioviral Antigen for CTL Priming
Maria Carmen Ramirez Mazcunyan,
Fox Chase Cancer Center, USA
Short Talk: Macrophages and Dendritic Cells Use the Cytosolic Pathway to Rapidly Cross-Present Antigen from Live, Vaccinia-Infected Cells
Short Talk: Macrophages and Dendritic Cells Use the Cytosolic Pathway to Rapidly Cross-Present Antigen from Live, Vaccinia-Infected Cells
Nicolas Glaichenhaus,
Centre National de la Recherche Scientifique, France
Short Talk: CD11b+ Dendritic Cells are Responsible for the Activation of CD4+ T Cells in Mice Infected with the Intracellular Parasite Leishmania Major
Short Talk: CD11b+ Dendritic Cells are Responsible for the Activation of CD4+ T Cells in Mice Infected with the Intracellular Parasite Leishmania Major
Lélia Delamarre,
Genentech, Inc., USA
Short Talk: Presentation of Exogenous Antigens on MHC I and MHC II is Differentially Regulated during Dendritic Cell Maturation
Short Talk: Presentation of Exogenous Antigens on MHC I and MHC II is Differentially Regulated during Dendritic Cell Maturation
08:00—11:00
Transmission of Signals to the Nucleus: General Principles (Joint)
Meeting has ended...abstracts no longer viewable online.
Joseph Schlessinger,
Yale University School of Medicine, USA
Tyrosine Kinases
Tyrosine Kinases
Amer A. Beg,
Moffitt Cancer Center, USA
NF-kappaB Signaling in Dendritic Cells
NF-kappaB Signaling in Dendritic Cells
*
Richard A. Flavell,
HHMI/Yale University School of Medicine, USA
Signal-Mediated Control of Transcription
Signal-Mediated Control of Transcription
Gioacchino Natoli,
Humanitas University, Italy
Close-Ups of NF-kappa B Recruitment to Target Genes in DCs
Close-Ups of NF-kappa B Recruitment to Target Genes in DCs
Takashi Kobayashi,
University of Pennsylvania, USA
Short Talk: TRAF6 Regulates Dendritic Cell Development and Function
Short Talk: TRAF6 Regulates Dendritic Cell Development and Function
Salome Landmann,
Centre Medical Universitaire, Switzerland
Short Talk: The Role of the Class II Transactivator (CIITA) in Dendritic Cells
Short Talk: The Role of the Class II Transactivator (CIITA) in Dendritic Cells
14:00—16:30
Workshop 3: Rafts: Fact or Fiction? (Joint)
*
Derek Toomre†,
Yale University School of Medicine, USA
Christian O. Meyer zum Buschenfelde†,
Yale University, USA
Recruitment of CD28 and CD86 to Lipid Rafts during DC-T Cell Interaction Results in Efficient T Cell Priming
Recruitment of CD28 and CD86 to Lipid Rafts during DC-T Cell Interaction Results in Efficient T Cell Priming
Jeoung-Sook Shin,
University of California, San Francisco, USA
Mast Cell Endo/Exocytosis of Particulate Allergens
Mast Cell Endo/Exocytosis of Particulate Allergens
Neil Poloso,
Allergan Inc., USA
Kinetics of MHC Class II Complex Association with Lipid Rafts
Kinetics of MHC Class II Complex Association with Lipid Rafts
Lee Leserman,
Centre d'Immunologie de Marseille-Luminy, France
MHC Class II/Peptide Complexes in Lipid Microdomains at The Dendritic Cell Surface Initiate the TH1 CD4 T Cell Phenotype
MHC Class II/Peptide Complexes in Lipid Microdomains at The Dendritic Cell Surface Initiate the TH1 CD4 T Cell Phenotype
Richard M. Siegel,
NIAMS, National Institutes of Health, USA
Lipid Microdomains and Receptor Clustering in Fas/CD95 Signaling
Lipid Microdomains and Receptor Clustering in Fas/CD95 Signaling
Alessandra Cambi,
Max Planck Institute for Biophysical Chemistry, Germany
Distribution of LFA-1 and DC-SIGN in Microdomains on DC by High Resolution Microscopy: Consequences for Cell-Adhesion and Ligand Binding
Distribution of LFA-1 and DC-SIGN in Microdomains on DC by High Resolution Microscopy: Consequences for Cell-Adhesion and Ligand Binding
Juli J. Unternaehrer,
Children's Hospital Boston, USA
Surface MHC-II I-E Associates with I-A in Dendritic Cells but Not in B Cells
Surface MHC-II I-E Associates with I-A in Dendritic Cells but Not in B Cells
17:00—19:00
Signal Transduction and Antigen Presentation (Joint)
Meeting has ended...abstracts no longer viewable online.
*
Richard A. Flavell,
HHMI/Yale University School of Medicine, USA
Tsuneyasu Kaisho,
RIKEN Research Center for Allergy and Immunology, Japan
Pleiotropic Function of Toll-Like Receptors on Dendritic Cells
Pleiotropic Function of Toll-Like Receptors on Dendritic Cells
Alan Aderem,
Center for Infectious Disease Research, USA
Macrophage Phagocytosis: from Genes to Function
Macrophage Phagocytosis: from Genes to Function
Ruslan Medzhitov,
HHMI/Yale University School of Medicine, USA
Toll Pathway of Host Defense
Toll Pathway of Host Defense
Caetano Reis e Sousa,
Francis Crick Institute, UK
Short Talk: Non-Plasmacytoid Dendritic Cells Act as Interferon-Producing Cells in Response to Cytosolic Double-Stranded RNA
Short Talk: Non-Plasmacytoid Dendritic Cells Act as Interferon-Producing Cells in Response to Cytosolic Double-Stranded RNA
08:00—11:00
Endocytosis and Lysosomal Transport (Joint)
Meeting has ended...abstracts no longer viewable online.
*
Ira Mellman,
Genentech, Inc., USA
Scott D. Emr,
Cornell University, USA
Receptor Down-Regulation and Protein Sorting at the Multivesicular Body
Receptor Down-Regulation and Protein Sorting at the Multivesicular Body
Margaret S. Robinson,
University of Cambridge, UK
Coat proteins and sorting
Coat proteins and sorting
Suzanne R. Pfeffer,
Stanford University, USA
Rab GTPases in Receptor Trafficking
Rab GTPases in Receptor Trafficking
Giorgio Scita,
IFOM Foundation at Campus IFOM-IEO, Italy
Integration of Signals Leading to Actin Remodeling and Endocytosis
Integration of Signals Leading to Actin Remodeling and Endocytosis
Angela Stoddart,
University of California, San Francisco, USA
Short Talk: Deciphering the Roles of Lipid Rafts and Clathrin in BCR Internalization
Short Talk: Deciphering the Roles of Lipid Rafts and Clathrin in BCR Internalization
Haoran Zhao,
Genentech, USA
Short Talk: TRAC-1, A Novel Lymphocyte-Specific E3 Ubiquitin Ligase, Regulates T Cell Activation Downstream of TCR Engagement
Short Talk: TRAC-1, A Novel Lymphocyte-Specific E3 Ubiquitin Ligase, Regulates T Cell Activation Downstream of TCR Engagement
17:00—19:00
Mechanisms of Proteolysis in the Cytosol (Joint)
Meeting has ended...abstracts no longer viewable online.
*
Ira Mellman,
Genentech, Inc., USA
Wolfgang P. Baumeister,
Max Planck Institute of Biochemistry, Germany
Electron Tomography: Visualizing Macromolecular Complexes in Intact Cells
Electron Tomography: Visualizing Macromolecular Complexes in Intact Cells
Jack R. Bennink,
NIAID, National Institutes of Health, USA
The Origin of Antigenic Peptides and Proteasomal Degradation of Newly Synthesized Proteins
The Origin of Antigenic Peptides and Proteasomal Degradation of Newly Synthesized Proteins
Alfred L. Goldberg,
Harvard Medical School, USA
Peptidases that Function after the Proteasome and Regulate Antigen Presentation
Peptidases that Function after the Proteasome and Regulate Antigen Presentation
08:00—11:00
Functional Specializations of the Endocytic Pathway
Meeting has ended...abstracts no longer viewable online.
*
Ralph M. Steinman,
Rockefeller University, USA
Christopher V. Nicchitta,
Duke University School of Medicine, USA
Heat Shock Proteins and Antigen Presentation
Heat Shock Proteins and Antigen Presentation
Sergio Grinstein,
Hospital for Sick Children, Canada
Role of Phosphoinositides in Phagosome Formation and in Bacterial Invasion
Role of Phosphoinositides in Phagosome Formation and in Bacterial Invasion
Dorothee Schmid,
Rockefeller University, USA
Short Talk: A Novel Pathway for Endogenous MHC Class II Presentation of a Nuclear Viral Antigen that Involves Autophagy
Short Talk: A Novel Pathway for Endogenous MHC Class II Presentation of a Nuclear Viral Antigen that Involves Autophagy
Dan R. Littman,
HHMI/New York University School of Medicine, USA
DC-SIGN and Transmission of HIV-1 Following Endocytosis
DC-SIGN and Transmission of HIV-1 Following Endocytosis
Eduardo Sergio Trombetta,
Yale University, USA
Regulation of Lysosomal Function in Dendritic Cells
Regulation of Lysosomal Function in Dendritic Cells
Thomas J. Hope,
Northwestern University, USA
Short Talk: Enhancement of HIV Infection by Dendritic Cells: Transfer of HIV to Target Cells Through an Infectious Synapse
Short Talk: Enhancement of HIV Infection by Dendritic Cells: Transfer of HIV to Target Cells Through an Infectious Synapse
14:00—16:30
Workshop 4: Mechanisms of Antigen Processing and Presentation
*
Ira Mellman,
Genentech, Inc., USA
*
Hans-Georg Rammensee,
University of Tübingen, Germany
Deborah Palliser,
Shire Pharmaceuticals, USA
Delineation of the Pathway Taken by a Heat Shock Fusion Protein to Gain Access to the MHC Class I Processing Pathway in Dendritic Cells
Delineation of the Pathway Taken by a Heat Shock Fusion Protein to Gain Access to the MHC Class I Processing Pathway in Dendritic Cells
Dorian B. McGavern,
National Institutes of Health, USA
Visualizing Antigen-Specific T Cells Involved in Immunopathogenesis
Visualizing Antigen-Specific T Cells Involved in Immunopathogenesis
Scott A. Wetzel,
University of Montana, USA
Peptide Specific Transfer of MHC From APC to T cells Through the Immunological Synapse
Peptide Specific Transfer of MHC From APC to T cells Through the Immunological Synapse
Heiichiro Udono,
Nagasaki University, Japan
Two Distinct Pathways Mediated by PA28 and hsp90 in Antigen Processing that is Linked with MHC I Polymorphism
Two Distinct Pathways Mediated by PA28 and hsp90 in Antigen Processing that is Linked with MHC I Polymorphism
Michael F. Princiotta,
SUNY Upstate Medical University, USA
Quantitating Viral Protein Synthesis, Degradation and Endogenous Antigen Processing
Quantitating Viral Protein Synthesis, Degradation and Endogenous Antigen Processing
Ona E. Bloom,
Yale University School of Medicine, USA
Spinophilin, a Neuronal Protein at the Immunological Synapse
Spinophilin, a Neuronal Protein at the Immunological Synapse
Julie Magarian Blander,
Weill Cornell Medicine, Cornell University, USA
Signals from Toll-Like Receptors Control Phagolysosomal Fusion
Signals from Toll-Like Receptors Control Phagolysosomal Fusion
Babak Javid,
Tsinghua University School of Medicine, China
Efficient Cross-Presentation of Mycobacterial Heat Shock Protein / Antigen Complexes by Human Dendritic Cells
Efficient Cross-Presentation of Mycobacterial Heat Shock Protein / Antigen Complexes by Human Dendritic Cells
Wilfred A. Jefferies,
University of British Columbia, Canada
The Cytoplasmic Domain of MHC Class I Proteins Controls Intracellular Trafficking and Cross-Presentation
The Cytoplasmic Domain of MHC Class I Proteins Controls Intracellular Trafficking and Cross-Presentation
Marco A. Purbhoo,
Howard Hughes Medical Institute, USA
Differential Dynamics of CD8, TCR, and MHC at the Immunological Synapse
Differential Dynamics of CD8, TCR, and MHC at the Immunological Synapse
17:00—19:00
Cell Migration
Meeting has ended...abstracts no longer viewable online.
*
Ralph M. Steinman,
Rockefeller University, USA
Ulrich H. Von Andrian,
Harvard Medical School, USA
T Cell Traffic and Interactions With DC in Lymphoid Tissues
T Cell Traffic and Interactions With DC in Lymphoid Tissues
Gwendalyn J. Randolph,
Washington University, USA
Dendritic Cell Migration from the Periphery to Lymph Nodes and Spleen: Insights from Analysis during Atherosclerotic Disease
Dendritic Cell Migration from the Periphery to Lymph Nodes and Spleen: Insights from Analysis during Atherosclerotic Disease
Tatyana Svitkina,
University of Pennsylvania, USA
Actin Machinery at the Leading Edge of Migrating Cells
Actin Machinery at the Leading Edge of Migrating Cells
Smita Nair,
Duke University School of Medicine, USA
Short Talk: Injection of Immature Dendritic Cells into Adjuvant Treated Skin Obviates the Need for ex vivo Maturation.
Short Talk: Injection of Immature Dendritic Cells into Adjuvant Treated Skin Obviates the Need for ex vivo Maturation.
08:00—11:00
Consequences of Cell Adhesion
Meeting has ended...abstracts no longer viewable online.
*
Ralph M. Steinman,
Rockefeller University, USA
Gillian Griffiths,
Cambridge Institute for Medical Research, UK
The Genetics of Cytotoxic T Cell Polarization and Secretion
The Genetics of Cytotoxic T Cell Polarization and Secretion
Michael O. Hengartner,
University of Zürich, Switzerland
C. elegans CED Proteins and Engulfment of Apoptotic Cells
C. elegans CED Proteins and Engulfment of Apoptotic Cells
Josef M. Penninger,
Institute of Molecular Biotechnology GmbH, Austria
Dendritic Cells, Autoimmunity and Infectious Stimuli
Dendritic Cells, Autoimmunity and Infectious Stimuli
Thomas M. Moran,
Mount Sinai School of Medicine, USA
Short Talk: Influenza Virus Induced Dendritic Cell Maturation In Vivo Correlates with Induction of Immune Responses to Co-Administered Antigen
Short Talk: Influenza Virus Induced Dendritic Cell Maturation In Vivo Correlates with Induction of Immune Responses to Co-Administered Antigen
Matthew F. Krummel,
University of California, San Francisco, USA
Short Talk: Functional Motor Proteins in T Cell Synapse Formation
Short Talk: Functional Motor Proteins in T Cell Synapse Formation
14:00—16:30
Workshop 5: Harnessing Cell Biology During Vaccination and Immunotherapy
*
Jacques F. Banchereau,
The Jackson Laboratory for Genomic Medicine, USA
*
Ralph M. Steinman,
Rockefeller University, USA
Wei Chen,
University of Minnesota, USA
CpG ODN Activates Human Natural Killer Cells Predominantly via an Indirect Mechanism Through Plasmacytoid Dendritic Cells
CpG ODN Activates Human Natural Killer Cells Predominantly via an Indirect Mechanism Through Plasmacytoid Dendritic Cells
Venky Ramakrishna,
Medarex, Inc., USA
Targeting Antigens via CD206 Expressed on Human DCs Enables Cross-Presentation to CD8+ and CD4+ Effector T Cells
Targeting Antigens via CD206 Expressed on Human DCs Enables Cross-Presentation to CD8+ and CD4+ Effector T Cells
Clotilde Théry,
Institut Curie, France
Role of MFG-E8/lactadherin in T cell Activation by Dendritic Cell-Derived Exosomes
Role of MFG-E8/lactadherin in T cell Activation by Dendritic Cell-Derived Exosomes
Raphael Clynes,
Xencor, Inc., USA
Role of FcgammaRII on Dendritic Cells in the Retention of Immune Complexes: A Possible Antigen-Recycling Pathway
Role of FcgammaRII on Dendritic Cells in the Retention of Immune Complexes: A Possible Antigen-Recycling Pathway
Kate C. Agopsowicz,
AltaRex Corporation, Canada
Opsonization with Specific Antibodies Enhances Dendritic cell Presentation of Apoptotic Tumor Cells and Induction of CTL
Opsonization with Specific Antibodies Enhances Dendritic cell Presentation of Apoptotic Tumor Cells and Induction of CTL
Holger Kanzler,
Bill & Melinda Gates Foundation, USA
ISS-Antigen Conjugates Enhance MHC Class I Antigen Presentation
ISS-Antigen Conjugates Enhance MHC Class I Antigen Presentation
Hua E. Yu,
Beckman Research Institute, City of Hope, USA
STAT3 Activity in Tumor Cells Negatively Regulates Dendritic Cell Activation and Maturation
STAT3 Activity in Tumor Cells Negatively Regulates Dendritic Cell Activation and Maturation
Shin-Ichiro Fujii†,
RIKEN IMS, Japan
Activation of Natural Killer Cells by alpha Galactosyl Ceramide Rapidly Induces the Full Maturation of Dendritic Cells in Mice and Thereby Acts as an Adjuvant for CD4 and CD8 T Cell Immunity to a Co-Administered Protein
Activation of Natural Killer Cells by alpha Galactosyl Ceramide Rapidly Induces the Full Maturation of Dendritic Cells in Mice and Thereby Acts as an Adjuvant for CD4 and CD8 T Cell Immunity to a Co-Administered Protein
Jan C. Dudda,
Twincore, Germany
Targeting of CD8+ T Cells to Inflamed Skin by DC Immunization
Targeting of CD8+ T Cells to Inflamed Skin by DC Immunization
John P. Vasilakos,
Biothera, USA
Differential Activation of Human Innate Immune Cells using Small Molecule TLR Agonists
Differential Activation of Human Innate Immune Cells using Small Molecule TLR Agonists
Gaetan Jego,
Baylor Institute for Immunology Research, USA
Plasmacytoid Dendritic Cells Induce B and T Cell Memory Responses
Plasmacytoid Dendritic Cells Induce B and T Cell Memory Responses
Beatrice Laupeze†,
Baylor Institute for Immunology Research, USA
Different Dendritic Cells can Induce Different Types of T Cell Responses
Different Dendritic Cells can Induce Different Types of T Cell Responses
17:00—19:00
Cellular Mechanisms of Immune Evasion
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Ralph M. Steinman,
Rockefeller University, USA
Robert D. Schreiber,
Washington University School of Medicine, USA
The Three E’s of Cancer Immunoediting
The Three E’s of Cancer Immunoediting
Tak W. Mak,
Campbell Family Institute for Breast Cancer, Canada
Genetic Dissection of Lymphocyte Activation
Genetic Dissection of Lymphocyte Activation
Benoît J. Van den Eynde,
University of Louvain, Belgium
A Novel Tumor Immune Escape Mechanism based on tryptophan Degradation by Indoleamine 2,3 Dioxygenase
A Novel Tumor Immune Escape Mechanism based on tryptophan Degradation by Indoleamine 2,3 Dioxygenase
Eric C. Bartee,
Oregon Health & Science University, USA
Short Talk: Downregulation of Cell Surface Receptors by a Family of Human Ubiquitin Ligases Homologous to Viral Immune Evasion Proteins
Short Talk: Downregulation of Cell Surface Receptors by a Family of Human Ubiquitin Ligases Homologous to Viral Immune Evasion Proteins
*Session Chair †Invited, not yet responded.
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