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This meeting took place in 2003



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RNA Trafficking, Transport and Processing (E5)


Organizer(s) Anne Ephrussi, Iain W. Mattaj and Gideon Dreyfuss
April 5—10, 2003
Snowbird Resort • Snowbird, Utah USA
Abstract Deadline: Dec 5, 2002
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Feb 5, 2003

Supported by Keystone Symposia

Summary of Meeting:
Recent exciting developments in the field of RNA transport include the revelation that RNA processing, exit from the nucleus and identification in the cytoplasm are related processes, mediated by highly dynamic protein-RNA interactions. Proteins deposited on RNAs co-transcriptionally and through splicing appear to be critical to the subsequent fate of mRNA. Although their functions and to some extent even their identities are not clear, these proteins determine the properties of the mRNA with which they associate. They affect the nuclear export, stability and likely other cytoplasmic aspects of the life of an mRNA. The nuclear RNP remodeling events, how very large mRNP complexes get through the nuclear pore, how they associate with the cytoskeletal components required for their localization, how specificity of localization is determined and how translational repression of the unlocalized mRNA and local translational activation are achieved are now among the central questions. The goal of the meeting is to bring together scientists working at each level in the metabolism of mRNA, from it's co-transcriptional processing to its eventual translation and stability properties. It is at the interfaces between these different sub-disciplines that we hope to encourage interaction and progress.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SATURDAY, APRIL 5

15:00—19:00
Registration

Ballroom Lobby
18:15—19:15
Welcome

Ballroom Lobby

SUNDAY, APRIL 6

07:00—08:00
Breakfast

Golden Cliff
08:00—08:15
Orientation

Ballroom 3
08:15—11:00
Pre-mRNA Processing
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Peter Walter, HHMI/University of California, San Francisco, USA

Christine Guthrie, University of California, San Francisco, USA
SUB2: A "DEAD-Box" ATPase Required for Splicing and Export

James L. Manley, Columbia University, USA
RNA Processing and the Integration of Nuclear Events

Cindy Will, Max Planck Institute for Biophysical Chemistry, Germany
Structural Dynamics of the Spliceosome

Melissa J. Moore, Moderna Therapeutics, USA
Connections Between Pre-mRNA Splicing and mRNA Metabolism

09:20—09:40
Coffee Break

Ballroom Lobby
11:00—13:00
Poster Setup

Mezzanine
13:00—22:00
Poster Viewing

Mezzanine
16:30—17:00
Coffee & Snacks Available

Ballroom Lobby
17:00—19:00
Coupling pre-mRNA Processing and Export
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Christine Guthrie, University of California, San Francisco, USA

Peter Walter, HHMI/University of California, San Francisco, USA
Non-Conventional Splicing in the Unfolded Protein Response

Robin Reed, Harvard Medical School, USA
Coupling Transcription, Splicing and mRNA Export

Gideon Dreyfuss, HHMI/University of Pennsylvania School of Medicine, USA
The SMN Complex: An Assemblyosome for RNPs

19:00—20:00
Social Hour

Mezzanine
19:00—22:00
Poster Session 1

Mezzanine

MONDAY, APRIL 7

07:00—08:00
Breakfast

Golden Cliff
08:00—11:00
Other mRNA Export Pathways
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Ilan Davis, University of Edinburgh, UK

Bertil Daneholt, Karolinska Institute, Sweden
Specific Actin-Ribonucleoprotein Interactions are Required for Gene Expression

Elizabeth B. Goodwin, University of Wisconsin-Madison, USA
Regulated Nuclear Export Controls tra-2 Translation and Germline Development in C. elegans

Elisa Izaurralde, Max Planck Institute for Developmental Biology, Germany
Genome-Wide Analysis of mRNA Nuclear Export Pathways in Drosophila

Iain W. Mattaj, European Molecular Biology Laboratory, Germany
The RAN GTPase a Signal of Chromosome Position

09:20—09:40
Coffee Break

Ballroom Lobby
11:00—13:00
Poster Setup

Mezzanine
13:00—22:00
Poster Viewing

Mezzanine
16:30—17:00
Coffee & Snacks Available

Ballroom Lobby
17:00—19:00
RNA on the Move
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Elizabeth B. Goodwin, University of Wisconsin-Madison, USA

Ilan Davis, University of Edinburgh, UK
The Intracellular Trafficking of RNA Particles in Drosophila Embryos and Oocytes

Robert H. Singer, Albert Einstein College of Medicine, USA
The Birth and Travels of mRNA

John H. Carson, University of Connecticut Health Center, USA
RNA Granule Assembly and Dynamics

19:00—20:00
Social Hour

Mezzanine
20:00—22:00
Poster Session 2

Mezzanine

TUESDAY, APRIL 8

07:00—08:00
Breakfast

Golden Cliff
08:00—11:00
RNA Localization in Development
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Ralf-Peter Jansen, University of Munich, Germany

Paul M. Macdonald, University of Texas at Austin, USA
Recognition of mRNA Localization Signals

Anne Ephrussi, European Molecular Biology Laboratory, Germany
Nuclear Factors Regulating oskar mRNA Localization and Translational Control

William M. Saxton, University of California, Santa Cruz, USA
Microtubule Motors and Motility in Early Development

William Theurkauf, University of Massachusetts Medical Center, USA
Microtubule-Dependent RNA Localization in Embryonic Axis Specification

09:20—09:40
Coffee Break

Ballroom Lobby
11:00—13:00
Poster Setup

Mezzanine
13:00—22:00
Poster Viewing

Mezzanine
16:30—17:00
Coffee & Snacks Available

Ballroom Lobby
17:00—19:00
RNA Localization and Translational Control
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* William M. Saxton, University of California, Santa Cruz, USA

Kelly A. Shepard, California Institute for Regenerative Medicine, USA
The Actin-Dependent RNA Transport Machinery of Saccharomyces cerevisiae Recognizes and Delivers a Wide Variety of Transcripts to tThe Tips Of Emerging Buds

Ralf-Peter Jansen, University of Munich, Germany
Nuclear and Cytoplasmic Events during Yeast RNA Trafficking

Robert B. Darnell, HHMI/Rockefeller University, USA
Neuronal RNA Binding Proteins: Linking Nuclear and Cytoplasmic Functions in the Brain

19:00—20:00
Social Hour

Mezzanine
20:00—22:00
Poster Session 3

Mezzanine

WEDNESDAY, APRIL 9

07:00—08:00
Breakfast

Golden Cliff
08:00—11:00
Translational Regulation
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Peter Walter, HHMI/University of California, San Francisco, USA

Robin P. Wharton, Duke University Medical Center, USA
Translational Control in the Drosophila Embryo

Matthias W. Hentze, European Molecular Biology Laboratory, Germany
Messenger RNPs Regulating mRNA Translation

David P. Bartel, HHMI, MIT and Whitehead Institute, USA
MicroRNAs in Animals and Plants

Joel D. Richter, University of Massachusetts Medical School, USA
Translational Control by CPEB

09:20—09:40
Coffee Break

Ballroom Lobby
16:30—17:00
Coffee & Snacks Available

Ballroom Lobby
17:00—19:00
Regulation of RNA Stability
Meeting has ended...abstracts no longer viewable online.

Ballroom 3
* Matthias W. Hentze, European Molecular Biology Laboratory, Germany

Roy R. Parker, HHMI/University of Colorado, USA
Mechanisms and Control of mRNA Turnover in a Simple Eukaryote

David Tollervey, University of Edinburgh, UK
Pathways for Nuclear RNA Degradation

Michael M. Rosbash, Brandeis University, USA
Regulatory Provisional Steps in Yeast mRNA Export

19:00—20:00
Social Hour

Golden Cliff/Eagles Nest
20:00—23:00
Entertainment

Golden Cliff/Eagles Nest

THURSDAY, APRIL 10

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 CA099297-01




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