Granlibakken Tahoe Floorplan

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This meeting took place in 2004



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Hematopoiesis (D2)


Organizer(s) James N. Ihle and Stuart H. Orkin
March 12—17, 2004
Granlibakken Tahoe • Tahoe City, California USA
Abstract Deadline: Nov 12, 2003
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 12, 2004

Sponsored in part by the Director's Sponsor Fund

Summary of Meeting:
The goal of the meeting is to bring together investigators working on various aspects of hematopoiesis. Through the exchange of knowledge and ideas, it is anticipated that new concepts and approaches to hematopoiesis will arise. During the last few years our understanding of the regulation of hematopoiesis at the molecular level has greatly increased. This has resulted from the identification of the genes that are involved and the use of mammalian genetic approaches to precisely define the roles of individual genes. One of the challenges of the new information has been to integrate the rapidly expanding data to more accurately define the processes involved. An understanding of the individual genes and their interrelationship in controlling normal hematopoiesis will further our understanding of the malignant transformation of hematopoietic cells and provide additional targets for the rational development of therapeutic agents. A more detailed understanding of hematopoiesis will allow the identification of points for therapeutic intervention.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


FRIDAY, MARCH 12

15:00—19:00
Registration

Pre-Function
19:15—19:30
Orientation

Mountain/Lake Rooms

SATURDAY, MARCH 13

07:00—08:00
Breakfast

Granhall
08:00—11:00
Hematopoietic Stem Cell Biology
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Irving L. Weissman, Stanford University, USA
Biology of Stem Cell and Progenitor Cells

* Gordon M. Keller, University Health Network, MaRS Centre, Canada
Mesoderm Commitment to the Hemangioblast

George Q. Daley, HHMI/Boston Children's Hospital, USA
Engrafting Blood from ES Cells

Elaine A. Dzierzak, University of Edinburgh, Netherlands
AGM Hematopoietic Stem Cells: Microenvironment and Molecules

Atsushi Kunisato, Kirin Brewery Company, Ltd., Japan
Short Talk: Stem Cell Leukemia (SCL) Directs Hematopoietic Stem Cell Fate

09:20—09:40
Coffee Break

Pre-Function
11:00—13:00
Poster Setup

Bay Room
13:00—22:00
Poster Viewing

Bay Room
16:30—17:00
Coffee & Snacks Available

Pre-Function
17:00—19:00
Lymphoid Commitment and Differentiation
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Katia Georgopoulos, Massachusetts General Hospital, USA
Mission Impossible in T Cell Development

Meinrad Busslinger, Research Institute of Molecular Pathology, Austria
Transcriptional Control of Early Lymphophoiesis

* Rudolf Grosschedl, Max Planck Institute of Immunobiology and Epigenetics, Germany
Long-Range Regulation of the Immunologlobulin Heavy Chain Locus by SATB2

Mariaestela Ortiz, National Cancer Institute, National Institutes of Health, USA
Short Talk: Bcl11a is a Zinc Finger Protein Required for B and T Cell Development and May Function as a T-cell Tumor Suppressor

19:00—20:00
Dinner

Granhall
20:00—22:30
Poster Session 1

Bay Room
20:00—21:00
Social Hour

Bay Room

SUNDAY, MARCH 14

07:00—08:00
Breakfast

Granhall
08:00—11:00
Transcriptional Factors in Lymphocyte Differentiation and Function
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
* Harinder Singh, Cincinnati Children's Hospital Medical Center, USA
Regulation of Lympho- and Myelopoiesis by PU.1 and its Interacting IRF Partners

Terence H. Rabbitts, MRC Laboratory of Molecular Biology, UK
Modelling Chromosomal Translocations Encode Proteins Affecting Haematopoiesis and Leukaemogenesis

Warren S. Alexander, Walter and Eliza Hall Institute of Medical Research, Australia
New Hematopoietic Mutations through Random Mutagenesis

Hans C. Clevers, Hubrecht Institute, Netherlands
Wnt Signaling in the Intestine

Michael P. Cooke, Genomics Institute of the Novartis Research Foundation, USA
Short Talk: “Mega”: An ENU-Induced Allele of c-Myb Reveals an Essential Role for c-Myb–p300 Interaction in Lineage Commitment of HSCs and Progenitors

09:20—09:40
Coffee Break

Pre-Function
11:00—13:00
Poster Setup

Bay Room
13:00—22:00
Poster Viewing

Bay Room
16:30—17:00
Coffee & Snacks Available

Pre-Function
17:00—19:00
Control of Early Myeloid Lineage Commitment
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Leonard I. Zon, HHMI/Boston Children's Hospital, USA
HSCs: Molecular Aspects

* Stuart H. Orkin, Dana-Farber Cancer Institute, USA
HSCs: Molecular Aspects

Daniel G. Tenen, Cancer Science Institute, Singapore
Myeloid Transcription Factors: Effect on Stem Cells, Hematopoiesis, and Leukemia

Catherine V. Laiosa, Albert Einstein College of Medicine, USA
Short Talk: C/EBP Factors Reprogram T Cells Precursors into Myeloid Cells

19:00—20:00
Dinner

Granhall
20:00—22:30
Poster Session 2

Bay Room
20:00—21:00
Social Hour

Bay Room

MONDAY, MARCH 15

07:00—08:00
Breakfast

Granhall
08:00—11:00
Survival of Hematopoietic Cells
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Joseph T. Opferman, St. Jude Children's Research Hospital, USA
Obligate Roles for MCI-I during Apoptosis

* Craig B. Thompson, Memorial Sloan Kettering Cancer Center, USA
Regulators of Hematopoietic Cell Survival: Getting Beyond Bcl-2 Proteins

John C. Reed, F. Hoffmann-La Roche AG, Switzerland
Strategies for Restoring Apoptosis Sensitivity in Hematological Malignancies

A. Thomas Look, Dana-Farber Cancer Institute, USA
Emerging Genetics of T-Cell Leukemia and Lymphoma

Yuki Kimura, Memorial Sloan-Kettering Cancer Center, USA
Short Talk: Kit Receptor Tyrosine Kinase Regulates B-Cell and Megakaryocyte Development through Its Juxtamembrane Domain

09:20—09:40
Coffee Break

Pre-Function
11:00—13:00
Poster Setup

Bay Room
13:00—22:00
Poster Viewing

Bay Room
16:30—17:00
Coffee & Snacks Available

Pre-Function
17:00—19:00
Cytokine Signal Transduction in Hematopoiesis
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
* James N. Ihle, St. Jude Children's Research Hospital, USA
Cytokine Receptor Superfamily Signal Transduction

Douglas J. Hilton, Walter and Eliza Hall Institute of Medical Research, Australia
SOCS Proteins: Negative Regulators of Cytokine Signaling

Ikuo Nobuhisa, Institute of Molecular Embryology and Genetics, Kumamoto University, Japan
Short Talk: Spred-2 Suppresses Aorta-Gonad-Mesonephros Hematopoiesis by Inhibiting MAP Kinase Activation

19:00—20:00
Dinner

Granhall
20:00—22:30
Poster Session 3

Bay Room
20:00—21:00
Social Hour

Bay Room

TUESDAY, MARCH 16

07:00—08:00
Breakfast

Granhall
08:00—11:00
Signal Transduction in Lymphocyte Survival, Growth and Differentiation
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Michael Karin, University of California, San Diego, USA
The IKK NF-kappaB System in Innate Immunity and Maintenance of Macrophage Survival: Expectations and Surprises

Dan R. Littman, HHMI/New York University School of Medicine, USA
Signaling in Thymocyte Survival and Lymphoid Organ Development

John C. Cambier, University of Colorado SOM, USA
A Novel Alum Induced Myeloid Cell Promotes B-Cell Activation and Generation of Humoral Immune Responses

* Owen N. Witte, HHMI/University of California, Los Angeles, USA
Units of Function for the Immune System

Raul Mostoslavsky, Harvard Medical School, USA
Short Talk: Functional Characterization of Mammalian Sir2 Homologues

09:20—09:40
Coffee Break

Pre-Function
16:30—17:00
Coffee & Snacks Available

Pre-Function
17:30—19:00
Chromosomal Patterning in Gene Regulation
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
* Mark Groudine, Fred Hutchinson Cancer Research Center, USA
Approaching the Genomic Organization of Cellular Differentiation

Hitoshi Okada, Ontario Cancer Institute, Canada
Loss of Survivin Induces p53- and Bc12-Independent Catastrophic Cell Death in Mitosis

Takeshi Egawa, Washington University in St. Louis, USA
Short Talk: Study of CD4 Gene Regulation as a Model for Epigenetic Gene Silencing - Role of Runx Transcription Factors

19:00—20:00
Social Hour

Granhall
20:00—21:00
Dinner

Mountain/Lake Rooms
21:00—00:00
Entertainment

Mountain/Lake Rooms

WEDNESDAY, MARCH 17

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13-HL075518-01




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