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This meeting took place in 2004



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Genetic Manipulation of Insects (B3)


Organizer(s) David A. O'Brochta, Anthony A. James, Carolina V. Barillas-Mury, Alexander S. Raikhel and Janet Hemingway
February 3—8, 2004
Sagebrush Inn & Suites • Taos, New Mexico USA
Abstract Deadline: Oct 2, 2003
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 3, 2003

Supported by Keystone Symposia

Summary of Meeting:
Insect molecular genetics is growing rapidly and its application will be of increasing significance to humankind. Some key developments include the completion of insect genome sequencing projects, the development of germ-line transformation technologies, the routine production of transgenic insects and the creation of genetically modified mosquitoes to block pathogen transmission. Despite progress, pivotal problems remain, such as the identification of targets for genetic manipulation, development of methodologies to introduce and spread transgenes, mapping target insect population architecture, predicting the fate of transgenes and assessing the impact of transgenic insects on the environment and human health. We aim to assemble a multi-disciplinary group to discuss the Genetic Manipulation of Insects, foster dialog and technology transfer between scientists and encourage new collaborations. Risk and safety issues raised by genetically manipulating insects will be discussed, and interactions between young and established scientists will be encouraged to acquire broader perspectives of this new technology.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, FEBRUARY 3

15:00—19:00
Registration

Chamisa Lobby
18:15—19:15
Refreshments

Chamisa Lobby
19:15—19:30
Orientation

Chamisa Ballroom 1
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* David A. O'Brochta, University of Maryland Biotechnology Institute, USA

Barry J. Beaty, Colorado State University, USA
Targeting the Vector to Control Vector-Borne Diseases: Time to Translate


WEDNESDAY, FEBRUARY 4

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:00
Comparative Genomics
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* George Dimopoulos, Johns Hopkins University, USA

Hugh M. Robertson, University of Illinois at Urbana-Champaign, USA
The Apis mellifera Genome

Susan J. Brown, Kansas State University, USA
Tribolium Genetics and Genomics

Christos Louis, University of Crete, Foundation for Research and Technology, Greece
Be Fruitful and Multiply: Will the Additional Genomes Help us to Better Understand our Insects?

09:20—09:40
Coffee Break

Chamisa Lobby
11:00—13:00
Poster Setup

Chamisa Ballroom 2
13:00—22:00
Poster Viewing

Chamisa Ballroom 2
14:00—16:00
Workshop 1: Emerging Systems

Chamisa Ballroom 1
* Susan J. Brown, Kansas State University, USA

Claudia Husseneder, Louisiana State University AgCenter, USA
Termite Gut Bacteria as Trojan Horses for Gene Expression in Termite Colonies

Kofi Adasi, Virginia Bioinformatics Institute, USA
Kdr-Type Pyrethroid Resistance Occurs in the Molecular S Form of Anopheles gambiae sensu stricto in South-Eastern Ghana

Pia M. Untalan, U.S. Department of Agriculture, USA
Proteomic Analysis of the Cattle Tick, Boophilus microplus (Acari:Ixodidae), Using Two-Dimensional Polyacrylamide Gel Electrophoresis

Li-Chun Lin, University of Wisconsin-Madison, USA
Differential Filarial Worm Melanotic Encapsulation in Phenylalanine Hydroxylase Knockouts of Two Species of Mosquito Vectors

Kimberly M. Keene, Colorado State University, USA
Evidence for a Role of RNAi in Innate Immunity during Arboviral Infection in Mosquitoes

Corey L. Campbell, Colorado State University, USA
Functional Genomics of Vector Competence in the Arbovirus Vector, Culicoides spp.

Marcelo Ramalho-Ortigao, Kansas State University, USA
Studies of Molecular Interactions in the Sand Fly Midgut: From Characterization of Midgut cDNAs to RNA Interference

Martin Devenport, Johns Hopkins Bloomberg School of Public Health, USA
Analysis of the Anopheles gambiae Peritrophic Matrix Proteome

Julian A.T. Dow, University of Glasgow, UK
The Transcriptome and Proteome of a Drosophila Epithelium

16:30—17:00
Coffee & Snacks Available

Chamisa Lobby
17:00—19:00
Functional Genomics
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Hugh M. Robertson, University of Illinois at Urbana-Champaign, USA

George Dimopoulos, Johns Hopkins University, USA
Transcriptomic Analyses of Anopheles Infection Responses

Serap Aksoy, Yale University School of Public Health, USA
Influence of Microbial Genomes on Host Functions

Frank H. Collins, University of Notre Dame, USA
The Anopheles gambiae Genome

19:00—20:00
Social Hour

Chamisa Ballroom 2
19:30—22:00
Poster Session 1

Chamisa Ballroom 2

THURSDAY, FEBRUARY 5

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:00
Genetics of Insect Populations
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Janet Hemingway, Liverpool School of Tropical Medicine, UK

William C. Black IV, Colorado State University, USA
Testing Candidate Gene Function with Population Genomics

Allessandra della Torre, University of Rome La Sapienza, Italy
Incipient Speciation in Afrotropical Malaria Vectors

Maureen Coetzee, University of Witwatersrand, South Africa
Genetical Characterization of African Malaria Vectors

Fred Gould, North Carolina State University, USA
Mosquito Autocidal Control and Strain Replacement: Can Models Help?

09:20—09:40
Coffee Break

Chamisa Lobby
11:00—13:00
Poster Setup

Chamisa Ballroom 2
13:00—22:00
Poster Viewing

Chamisa Ballroom 2
14:00—16:00
Workshop 2: Release Issues

Chamisa Ballroom 1
* Frank H. Collins, University of Notre Dame, USA

Marjorie A. Hoy, University of Florida, USA
Risk Assessments Prior to Release of Transgenic and Paratransgenic Insects: Scientific Issues

Michael Rodemeyer, Pew Initiative on Food and Biotechnology, USA
Bugs in the System? Issues in the Regulation of Transgenic and Paratransgenic Insects

Greg Simmons, US Department of Agriculture, USA
Environmental, Regulatory and Scientific Issues Regarding the Development of New Pest Control Strategies for Pink Bollworm Using Transgenic Insects

Robert I. Rose, US Department of Agriculture, USA
Requirements for USDA Transgenic Arthropod Permits

Thomas W. Scott, University of California, Davis, USA
Measurable Decrease in Clinical Dengue following Vector Reduction in Iquitos, Peru

Willem Takken, Wageningen University, Netherlands
Life-History Strategies for Overcoming Genetic Interventions: The Case of Anopheles gambiae

Margaret (Meg) Louise Allen, US Department of Agriculture, ARS, USA
Fitness Characteristics of Transgenic Strains of the New World Screwworm, Cochliomyia hominivorax

Michael Coleman, Liverpool School of Tropical Medicine, UK
GIS Mapping and Mathematical Modeling of Insecticide Resistance Genes through Anopheles Populations

16:30—17:00
Coffee & Snacks Available

Chamisa Lobby
17:00—19:00
Molecular Genetic Analysis of Insects I
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Carolina V. Barillas-Mury, NIAID, National Institutes of Health, USA

Janet Hemingway, Liverpool School of Tropical Medicine, UK
Insect Resistance to Pesticides

Hilary Ranson, Liverpool School of Tropical Medicine, UK
Deciphering the Molecular Basis of Metabolic Resistance to Insecticides in Malaria Vectors

Leslie B. Vosshall, Rockefeller University, USA
Molecular Genetics of Insect Olfaction

19:00—20:00
Social Hour

Chamisa Ballroom 2
19:30—22:00
Poster Session 2

Chamisa Ballroom 2

FRIDAY, FEBRUARY 6

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:00
Insect Interactions with Microorganisms
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Leslie B. Vosshall, Rockefeller University, USA

Fotis C. Kafatos, Imperial College London, UK
Mosquito Immunity

Carolina V. Barillas-Mury, NIAID, National Institutes of Health, USA
Immune Responses of Anopheline Midgut Epithelial Cells to Ookinete Invasion

Michael J. Lehane, Liverpool School of Tropical Medicine (LSTM), UK
Insect Midgut Immunity and Trypanosome Transmission

Otto Schmidt, University of Adelaide, Australia
An Extracellular Driving Force of Endocytosis and Cell-Shape Changes

09:20—09:40
Coffee Break

Chamisa Lobby
11:00—13:00
Poster Setup

Chamisa Ballroom 2
13:00—22:00
Poster Viewing

Chamisa Ballroom 2
14:00—16:00
Workshop 3: Technicalities

Chamisa Ballroom 1
* Pierre-Marie Couble, Université Claude Bernard, France

Peter W. Atkinson, University of California, Riverside, USA
Further Studies on the Hermes and Herves LAT Transposable Elements from Insects

Craig John Coates, Texas A & M University, USA
Site Specific Integration of the MosI and piggyBac Transposons

Ernst A. Wimmer, University of Bayreuth, Germany
Development of Re-Arrangable Gene Transfer Systems to Increase Transgene Stability

Austin Burt, Imperial College London, UK
Artificial Homing Endonucleases as Tools for Population Genetic Engineering

Brian D. Foy, Colorado State University, USA
Recombinant Alphaviruses for Gene Silencing and for Foreign Gene Expression in Vector Mosquitoes and in Non-Vector Insects

Paul David Shirk, US Department of Agriculture ARS, USA
Somatic Transformation by JcDNV-Derived Plasmids Requires the Presence of Internal Viral Sequences in Combination with a Viral Inverted Terminal Repeat

Luke S. Alphey, Oxitec Ltd, UK
Insect Population Suppression via Genetic Manipulation of Insects

16:30—17:00
Coffee & Snacks Available

Chamisa Lobby
17:00—19:00
Molecular Genetic Analysis of Insects II
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Alexander S. Raikhel, University of California Riverside, USA

Thomas C. Kaufman, Indiana University, USA
Comparing Embryogenesis and Limb Formation in a Hemi- and Holo- Metabolic Insect (The Long and the Short of It)

Michael W. Young, Rockefeller University, USA
A Molecular Network Composing the Drosophila Clock

David L. Denlinger, Ohio State University, USA
Molecular Regulation of Diapause

19:00—20:00
Social Hour

Chamisa Ballroom 2
19:30—22:00
Poster Session 3

Chamisa Ballroom 2

SATURDAY, FEBRUARY 7

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:00
Molecular Genetic Analysis of Insects III
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Anthony A. James, University of California, Irvine, USA

Elissa P. Lei, NIDDK, National Institutes of Health, USA
Chromatin Insulators and Nuclear Organization

Alexander S. Raikhel, University of California Riverside, USA
Molecular Basis of Anautogeny: The Nutritional Regulation of Mosquito Vitellogenesis

Pierre-Marie Couble, Université Claude Bernard, France
Drosophila Melanogaster Fertilization Mutants

David A. O'Brochta, University of Maryland Biotechnology Institute, USA
Integration and Post-Integration Behavior of Insect Gene Vectors

09:20—09:40
Coffee Break

Chamisa Lobby
16:30—17:00
Coffee & Snacks Available

Chamisa Lobby
17:00—19:00
Genetic Manipulation of Insects
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* David A. O'Brochta, University of Maryland Biotechnology Institute, USA

Marcelo Jacobs-Lorena, Johns Hopkins Bloomberg School of Public Health, USA
Transgenic Mosquito Fitness and Plasmodium-Anopheles Interactions

Anthony A. James, University of California, Irvine, USA
Gene Driver Strategy for Manipulation of Vector Mosquito Populations

Darryl Macer, University of Tsukuba, Japan
Ethical Issues in Vector Control using Genetically Modified Insects

19:00—20:00
Social Hour

Chamisa Lobby
20:00—23:00
Entertainment

Chamisa Ballroom 2

SUNDAY, FEBRUARY 8

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13AI60103-01




National Science Foundation (NSF)

Grant No. MCB-0335258




We gratefully acknowledge additional support for this conference from:

Bill & Melinda Gates Foundation

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