Fairmont Hotel Vancouver Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2004



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Molecular Cell Biology of Lipid Domains (D4)


Organizer(s) Richard G.W. Anderson, Michael S. Brown and Joseph L. Goldstein
March 26—31, 2004
Fairmont Hotel Vancouver • Vancouver, British Columbia Canada
Abstract Deadline: Nov 24, 2003
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Jan 27, 2004

Supported by Keystone Symposia

Summary of Meeting:
Lipid domains are a class of membrane domains that compartmentalize signaling modules, regulate the transport of ions, molecules and macromolecular complexes to specific cellular sites, and spatially organize signal transduction in polarized cells. The purpose of this meeting is to bring together a diverse set of investigators with the goal of exploring the molecular basis of lipid domain function. The topics to be discussed include: intracellular traffic of lipid domains; role of lipid domains in bacterial and viral pathogenesis; signal transduction from lipid domains; mechanisms of protein/lipid sorting by lipid domains; lipid traffic through lipid domains: structural basis of protein function in lipid domains; biogenesis of lipid domains; biophysics of lipid lateral organization.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


FRIDAY, MARCH 26

15:00—19:00
Registration

Vancouver Island Alcove
18:15—19:15
Refreshments

British Ballroom
19:15—19:30
Orientation

Columbia Ballroom
19:30—19:45
Opening Remarks
Meeting has ended...abstracts no longer viewable online.

Richard G.W. Anderson, University of Texas Southwestern Medical Center, USA

Michael S. Brown, University of Texas Southwestern Medical Center, USA

Joseph L. Goldstein, University of Texas Southwestern Medical Center, USA

19:45—20:45
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Kai Simons, Max Planck Institute of Molecular Cell Biology and Genetics, Germany
Lipid Rafts: Structure and Function


SATURDAY, MARCH 27

07:00—08:00
Breakfast

British Ballroom
08:00—11:00
Biophysics of Lipid Lateral Organization
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Harden M. McConnell, Stanford University, USA
Condensed Complexes of Cholesterol and Phospholipids

* Anne K. Kenworthy, Vanderbilt University School of Medicine, USA
Dynamics of Lipid Rafts at the Cell Surface

Akihiro Kusumi, Kyoto University, Japan
Calcium Signaling Induced by Transient Recruitment of PLCgamma to the Raft Stabilized by Clustering of GPI-Anchored Receptors: Single Molecule Observations

Ken Jacobson, University of North Carolina at Chapel Hill, USA
Detecting Lipid Domains in Living Cells

Nicole S. Sampson, Stony Brook University, USA
Short Talk: Cholesterol Oxidase Senses Subtle Changes in Lipid Bilayer Structure

09:20—09:40
Coffee Break

British Columbia Foyer
11:00—13:00
Poster Setup

British Ballroom
13:00—22:00
Poster Viewing

British Ballroom
16:30—17:00
Coffee & Snacks Available

British Columbia Foyer
17:00—19:00
Biogenesis and Maintenance of Lipid Domains: Intracellular Lipid Transport
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Dennis R. Voelker, National Jewish Health, USA
Protein and Lipid Motifs Regulating Lipid Traffic in Membrane Biogenesis

Geoffrey Chang, The Scripps Research Institute, USA
Structures of Multidrug Resistance ABC Transporter Homologs

* Richard G.W. Anderson, University of Texas Southwestern Medical Center, USA
Caveolae, Signal Transduction and Lipid Metabolism: What are the Connections?

Raquel F. Epand, McMaster University, Canada
Short Talk: Cholesterol-Dependent Partitioning of PIP2 into Membrane Domains by the Amino Terminal Fragment of NAP-22

19:00—20:00
Social Hour

British Ballroom
19:30—22:00
Poster Session 1: Biophysics of Lipid Lateral Organization/Biogenesis and Maintenance of Lipid Domains: Intracellular Lipid Transport and Protein Function in the Bilayer

British Ballroom

SUNDAY, MARCH 28

07:00—08:00
Breakfast

British Ballroom
08:00—11:00
Biogenesis and Maintenance of Lipid Domains: Protein Function in the Bilayer
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Hartmut Michel, Max Planck Institute for Biophysics, Germany
Structure of Membrane Proteins: Interaction with Lipids as Found by Crystallography

James H. Hurley, University of California, Berkeley, USA
Structural Mechanisms in Lipid Signaling and Metabolism

* Arthur E. Johnson, Texas A & M University System Health Science Center, USA
Cholesterol-Dependent Binding, Oligomerization, and Pore Formation by a Bacterial Protein Toxin

F. Gisou van der Goot, Federal Polytechnic School of Lausanne, Switzerland
Role of Lipid Domains in the Mode of Action of Bacterial Toxins

Vassilis I. Zannis, Boston University School of Medicine, USA
Short Talk: Physical and Functional Interactions between apoA-I and ABCA1 Variants Explain the Structural Requirements for Lipid Efflux and Biogenesis of HDL

09:20—09:40
Coffee Break

British Columbia Foyer
11:00—13:00
Poster Setup

British Ballroom
13:00—22:00
Poster Viewing

British Ballroom
16:30—17:00
Coffee & Snacks Available

British Columbia Foyer
17:00—19:00
Mechanisms of Protein/Lipid Sorting by Lipid Domains
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Richard E. Pagano, Mayo Clinic and Foundation, USA
Perturbation of Membrane Recycling by Stored Cholesterol in Niemann Pick Fibroblasts

Amy Chang, University of Michigan, USA
The Role of Lipid Rafts in Targeting to and Stability at the Yeast Plasma Membrane

* Scott D. Emr, Cornell University, USA
Lipid-Based Signaling in Endosomal Protein Sorting

Rutilio A. Fratti, University of Illinois at Urbana-Champaign, USA
Short Talk: Phosphoinositide Enrichment at the Vertex Ring Domain of Yeast Vacuoles is Required for Functional SNARE Distribution and Membrane Fusion

19:00—20:00
Social Hour

British Ballroom
19:30—22:00
Poster Session 2: Mechanisms of Protein/Lipid Sorting by Lipid Domains/Role of Lipids in Protein Sorting/Intracellular Traffic of Lipid Domains

British Ballroom

MONDAY, MARCH 29

07:00—08:00
Breakfast

British Ballroom
08:00—11:00
Role of Lipids in Protein Sorting
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Joseph L. Goldstein, University of Texas Southwestern Medical Center, USA
Insig-Dependent, Sterol-Regulated Membrane Proteins: Part I – SCAP

* Michael S. Brown, University of Texas Southwestern Medical Center, USA
Insig-Dependent, Sterol-Regulated Membrane Proteins: Part II - HMG CoA Reductase

Ian Collinson, University of Bristol, UK
Structure and Function of a Protein Conducting Channel

Howard Riezman, University of Geneva, Switzerland
Mechanisms of GPI-Anchored Protein Sorting Upon Exit from the Endoplasmic Reticulum

Tetsuya Takeda, Columbia University Medical Center, USA
Short Talk: Organization of a Sterol-Rich Membrane Domain by cdc15p during Cytokinesis in Fission Yeast

09:20—09:40
Coffee Break

British Columbia Foyer
11:00—13:00
Poster Setup

British Ballroom
13:00—22:00
Poster Viewing

British Ballroom
16:30—17:00
Coffee & Snacks Available

British Columbia Foyer
17:00—19:00
Intracellular Traffic of Lipid Domains
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Deborah A. Brown, Stony Brook University, USA
Palmitoylation and Intracellular-Domain Interactions Both Contribute to Raft Targeting of Linker for Activation of T Cells (LAT)

Robert G. Parton, University of Queensland, Australia
Ultrastructural Analysis of Caveolae and Lipid Raft Domains

Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA
The Golgi Apparatus: A Two Phase Membrane System for Protein Processing, Sorting and Secretory Transport

Leslie T. Grab, University of North Carolina at Chapel Hill, USA
Short Talk: Exosomes Provide a Conduit for Extracellular Production of Lysophosphatidic Acid by Ovarian Cancer Cells

19:00—20:00
Social Hour

British Ballroom
19:30—22:00
Poster Session 3: Signal Transduction from Lipid Domains/Role of Lipid Domains in Disease

British Ballroom

TUESDAY, MARCH 30

07:00—08:00
Breakfast

British Ballroom
08:00—11:15
Signal Transduction from Lipid Domains
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Linda J. Pike, Washington University School of Medicine, USA
Lipid Rafts and EGF Receptor Signaling

Susan K. Pierce, NIAID, National Institutes of Health, USA
The Role of Lipid Domains in Regulating Immune Cell Signaling

Philip A. Beachy, HHMI/Stanford University, USA
Cholesterol Anchors and Signal Transduction

Suzanne Eaton, Max Planck Institute, Germany
Argosomes: Lipidic Particles that Carry Wingless and Hedgehog

Oleg O. Glebov, MRC Laboratory of Molecular Biology, UK
Short Talk: Lipid Raft Proteins have a Random Distribution during Localized Activation of T-Cell Receptor

Cynthia Corley Mastick, University of Nevada, USA
Short Talk: Feedback Inhibition of Src Family Kinases through Phosphorylation of Caveolin-1 and Recruitment of Csk

09:20—09:40
Coffee Break

British Columbia Foyer
16:30—17:00
Coffee & Snacks Available

British Columbia Foyer
17:00—19:00
Role of Lipid Domains in Disease
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Ari Helenius, ETH Zurich, Switzerland
What Viruses Tell Us About Endocytosis

Soman N. Abraham, Duke University Medical Center, USA
Lipid Raft Mediated Entry and Escape of E.coli from Host Cells

Alessandra Cambi, Max Planck Institute for Biophysical Chemistry, Germany
Short Talk: Microdomains of DC-Sign are Portals for Virus Entry into Dendritic Cells

Dan J. Sillence, , UK
Short Talk: The Accumulation of Glycosphingolipids in Niemann-Pick C Disease Disrupts Endosomal Transport

Maho Morishima-Kawashima, Hokkaido University, Japan
Short Talk: Gamma-Secretase Activity to Generate Abeta is Present in Rafts, but not Cholesterol-Dependent

19:00—20:00
Social Hour

British Ballroom
20:00—23:00
Entertainment

British Ballroom

WEDNESDAY, MARCH 31

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:


Avanti Polar Lipids, Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676