Granlibakken Tahoe Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2004



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Emerging Mechanisms of Epigenetic Regulation (B1)


Organizer(s) Jeannie T. Lee and Vicki L. Chandler
January 21—26, 2004
Granlibakken Tahoe • Tahoe City, California USA
Abstract Deadline: Sep 22, 2003
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Nov 21, 2003

Sponsored in part by the Director's Sponsor Fund

Summary of Meeting:
EXECUTIVE SUMMARY: Epigenetics is an exciting and very rapidly moving field that impacts basic science, clinical medicine and agriculture. While an understanding of underlying processes is just beginning to emerge, basic questions about how epigenetic processes work and whether diverse processes share underlying mechanisms remain mysterious. This conference will attempt to find common themes and differences among epigenetic phenomena across all phyla (yeast, plants, animals). The meeting will emphasize the diversity of the phenomena and emerging paradigms for their control. As is becoming increasingly clear, overtly different processes find surprisingly similar strategies of regulation. Emphasis will also be placed on how epigenetic mechanisms affect clinical and agricultural interests. Upon completion of this conference, participants should be able to: - Recognize epigenetic processes across various taxa (plants, animals, yeast), including imprinting, allelic exclusion, transvection, cosuppression, quelling, and RIP/MIP. - Appreciate that these mechanisms may have evolved to regulate gene dosage, to maintain genome integrity, to defend against viruses and transposons. - Idenfity potential mediators of epigenetic phenomena such as RNA, DNA methylation, and chromatin modifiers. - Begin to recognize possible mechanistic links among diverse species and processes. - Understand how anomalies in epigenetic processes can lead to disease or and how therapeutic strategies might be design. - Emphasis is placed on imprinting disorders, genome integrity, animal cloning, cancer, and prions. - Appreciate the agricultural implications of epigenetics, such as those relating to plant viral defense mechanisms, animal cloning, and imprinting.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


WEDNESDAY, JANUARY 21

15:00—19:00
Registration

Pre-Function
19:15—19:30
Orientation

Mountain/Lake Rooms
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA
Nuclear Cloning, Stem Cells and the Reprogramming of the Genome


THURSDAY, JANUARY 22

07:00—08:00
Breakfast

Granhall
08:00—11:00
Allelic Exclusion
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Wolf Reik, Babraham Institute, UK
Mechanisms of Imprinting and Epigenetic Reprogramming

* Huntington F. Willard, Duke University, USA
X-Chromosome Inactivation in Mammals

Khanh Duc Huynh, Cell Signaling Technology, USA
Short Talk: Dosage Compensation is Established from the Time of Conception in Mice

Edith Heard, Institut Curie, France
Short Talk: Epigenetic Dynamics of X-Chromosome Inactivation during Pre-Implantation Development of the Mouse

Frank G. Grosveld, Erasmus University, Netherlands
Dynamics of the Globin Gene Compartment

Ben Shykind, Columbia University, College of Physicians and Surgeons, USA
Odorant Receptor Expression: One Neuron One Allele

Shou Serizawa, University of Tokyo, Japan
Short Talk: Negative Feedback Regulation Ensures One Receptor – One Olfactory Neuron Rule

09:20—09:40
Coffee Break

Pre-Function
11:00—13:00
Poster Setup

Bay Room
13:00—22:00
Poster Viewing

Bay Room
16:30—17:00
Coffee & Snacks Available

Pre-Function
17:00—19:15
Genomic Imprinting
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Alexander A. Gimelbrant, Dana-Farber Cancer Institute, USA
Short Talk: Asynchronous Replication and Monoallelic Expression in Mouse

Ueli Grossniklaus, University of Zürich, Switzerland
Genomic Imprinting during Seed Development in Arabidopsis thaliana

Nora I. Engel, Temple University School of Medicine, USA
Regulation of Imprinting at the H19/Igf2 Locus

Anne C. Ferguson-Smith, University of Cambridge, UK
Short Talk: Epigenetic Control at the Dlk1-Gtl2 Imprinted Domain on Mouse Distal Chromosome 12

Christine M. Williamson, Medical Research Council, UK
Short Talk: Identification of an Imprinting Control Region and a Role for the Non-Coding Antisense, Nespas in the Gnas Imprinting Cluster

* Denise P. Barlow, Center for Molecular Medicine, Austria
A Role for Non-Coding RNAs in Genomic Imprinting

19:15—20:15
Dinner

Granhall
20:00—22:30
Poster Session 1

Bay Room
20:15—21:15
Social Hour

Bay Room

FRIDAY, JANUARY 23

07:00—08:00
Breakfast

Granhall
08:00—11:00
Unusual Epigenetic Phenomena
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
* Carmen Sapienza, Temple University, USA
The Things that Happen between Males and Females: Lessons Learned from the DDK Mouse

Eric U. Selker, University of Oregon, USA
Genome Defense and DNA Methylation In Neurospora

Chao-Ting Wu, Harvard Medical School, USA
Transvection: Dating at the Genome Level

Vicki L. Chandler, Minerva Schools at Keck Graduate Institute, USA
Paramutation in Maize

Paul D. Soloway, Cornell University, USA
Short Talk: Paramutation and Trans-Allele Methylation in Mice

B. Tibor Roberts, NIDDK, National Institutes of Health, USA
Short Talk: Heritable Activity: A Prion that Propagates by Covalent Auto-Activation

09:20—09:40
Coffee Break

Pre-Function
11:00—13:00
Poster Setup

Bay Room
13:00—22:00
Poster Viewing

Bay Room
16:30—17:00
Coffee & Snacks Available

Pre-Function
17:00—19:15
DNA Methylation as Mediators
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
* Timothy H. Bestor, Columbia University College of Physicians and Surgeons, USA
The Methylation Landscape of the Human Genome

Rolf Ohlsson, Karolinska Institute, Sweden
The Mechanism of Genomic Imprinting: The CTCF/BORIS Connection

Steven E. Jacobsen, , USA
Genetics of DNA Methylation in Arabidopsis

Takashi Sado, National Institute of Genetics, Japan
Short Talk: De novo DNA Methylation is Dispensable for the Initiation and Propagation of X Chromosome Inactivation

Isao Suetake, Institute for Protein Research, Japan
Short Talk: DNMT3L Stimulates DNA Methylation Activity of Dnmt3a and Dnmt3b in vitro

19:15—20:15
Dinner

Granhall
20:00—22:30
Poster Session 2

Bay Room
20:15—21:15
Social Hour

Bay Room

SATURDAY, JANUARY 24

07:00—08:00
Breakfast

Granhall
08:00—11:00
RNA Mediators
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Peter Fraser, Florida State University, USA
Intergenic Transcription-Dependent Chromatin Modification is Required for Long-Range Enhancer Interactions

Jeannie T. Lee, Massachusetts General Hospital, USA
Noncoding Transcribed Elements of the X-Inactivation Center

* Marjori Ann Matzke, Institute of Plant and Microbial Biology, Academy Sinica, Taiwan
Genetic Analysis of RNA Directed DNA Methylation

Judith Bender, Brown University, USA
RNA Signals for DNA Methylation of Endogenous Genes in Arabidopsis

Hristo B. Houbaviy, Massachusetts Institute of Technology, USA
Short Talk: An Embryonic Stem Cell-Specific microRNA Cluster

Susanna Mlynarczyk-Evans, University of California, San Francisco, USA
Short Talk: X Chromosome Non-Equivalence in ES Cells Predicts Active and Inactive X Chromosome Fates

09:20—09:40
Coffee Break

Pre-Function
11:00—13:00
Poster Setup

Bay Room
13:00—22:00
Poster Viewing

Bay Room
16:30—17:00
Coffee & Snacks Available

Pre-Function
17:00—19:15
Nuclear Compartments
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Gary Felsenfeld, NIDDK, National Institutes of Health, USA
Vertebrate Chromatin Insulators and Boundaries

Nancy E. Cooke, University of Pennsylvania, USA
Short Talk: Roles of LCR Determinants in Long-Range Gene Activation

Séverine Chambeyron, Institute of Human Genetics, France
Short Talk: Altered Nuclear Organization of the Hoxb Locus upon Induction of High Levels of Transcription is not a Simple Consequence of Histone Acetylation

Abby F. Dernburg, University of California, Berkeley, USA
Short Talk: A Novel Regulator of Large-Scale Meiotic Chromosome Dynamics in C. elegans

Dirk Schübeler, Friedrich Miescher Institute for Biomedical Research, Switzerland
The Interplay between Histone Modifications, Transcription and DNA Replication

* Pamela K. Geyer, University of Iowa, USA
Genome Organization and Gene Regulation: The Role of Insulators in Defining Chromatin Domains

19:15—20:15
Dinner

Granhall
20:00—22:30
Poster Session 3

Bay Room
20:15—21:15
Social Hour

Bay Room

SUNDAY, JANUARY 25

07:00—08:00
Breakfast

Granhall
08:00—11:00
Chromatin Modifiers
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
* Robert E. Kingston, Massachusetts General Hospital, USA
Mechanisms to Target and Spread Repression by Polycomb-Group Complexes

Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Transposable Elements, RNA Interference and the Origin of Heterochromatin

Geneviève Almouzni, Centre National de la Recherche Scientifique, France
From Nucleosome to Heterochromatin: Their Formation and Maintenance

Steven Henikoff, Fred Hutchinson Cancer Research Center, USA
Nucleosome Assembly Pathways and the Maintenance of Chromatin States

Gary Karpen, Lawrence Berkeley National Laboratory, University of California, Berkeley, USA
Short Talk: Epigenetic Properties of Centromeric Chromatin

Nicole M. Hagemann, University of Chicago, USA
Short Talk: Genetic Analysis of the Role of Chromatin Structure in the Expression of Genes Located within the Centromeres of Arabidopsis

09:20—09:40
Coffee Break

Pre-Function
16:30—17:00
Coffee & Snacks Available

Pre-Function
17:00—19:15
Clinical and Agricultural Applications
Meeting has ended...abstracts no longer viewable online.

Mountain/Lake Rooms
Carole Charlier, University of Liège, Belgium
Polar Overdominance at the Ovine Callipyge locus Supports Trans Interaction between the Products of Reciprocally Imprinted Genes

Victor V. Lobanenkov, NIAID, National Institutes of Health, USA
CTCF and BORIS in Cancer (Epi)genetics

Luca Comai, University of California, Davis Genome Center, USA
Ploidy Changes and Epigenetics in Arabidopsis

Richard Amasino, University of Wisconsin, USA
Memories of Winter: Vernalization and the Competence to Flower

Shuang Chang, Emory University, USA
Short Talk: Identification of DOST1, a Dominant Suppressor of Methylation-Induced Transgene Silencing in Arabidopsis

19:15—20:15
Social Hour

Granhall
20:15—21:15
Dinner

Mountain/Lake Rooms
21:00—00:00
Entertainment

Mountain/Lake Rooms

MONDAY, JANUARY 26

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Science Foundation (NSF)

Grant No. MCB-0353041




We gratefully acknowledge additional support for this conference from:

March of Dimes Foundation Novartis Institutes for BioMedical Research

Improvision

 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676