Hilton Santa Fe Historic Plaza Hotel Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2004



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Mass Spectrometry in Systems Biology (B6)


Organizer(s) John R. Yates and Vicki H. Wysocki
February 14—19, 2004
Hilton Santa Fe Historic Plaza Hotel • Santa Fe, New Mexico USA
Abstract Deadline: Oct 15, 2003
Late Abstract Deadline:
Scholarship Deadline:
Early Registration Deadline: Dec 15, 2003

Supported by Keystone Symposia

Summary of Meeting:
Systems biology represents integration of measurements of genomics, gene transcription, proteomics and metabonomics. The completion of a genome sequence for an organism provides the basic set of proteins and enzymes that are present in the organism. In multi-cellular organisms each cell type uses a portion of the set genes to perform specialized functions. Cells must respond to changes in the environment, the molecules of the cell must do so as part of a system, and the cell must respond as part of the organism or physiology. Integral to understanding biological systems is the ability to discover and measure changes in the system. Mass spectrometry is a key technology for the measurement of molecular structure and molecular abundance. Mass spectrometry is being applied to the measurement of DNA, RNA, protein and small molecule metabolites. This meeting will present the latest developments in the methods and applications of mass spectrometry for the analysis of DNA, RNA, proteins and naturally occurring metabolites. Topics emphasizing global measurements as well as highly specific and accurate molecular measurements will be presented.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SATURDAY, FEBRUARY 14

15:00—19:00
Registration

Promenade
18:15—19:15
Refreshments

Promenade
19:15—19:30
Orientation

Mesa A-B
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* John R. Yates III, The Scripps Research Institute, USA

R. Graham Cooks, Purdue University, USA
Advances in Mass Spectrometry Instrumentation


SUNDAY, FEBRUARY 15

07:00—08:00
Breakfast

Chamisa
08:00—11:00
Technology I
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* R. Graham Cooks, Purdue University, USA

Stephen Naylor, Beyond Genomics, USA
Case Studies in System Biology: Role of Technologies

Marvin Vestal, Applied Biosystems, USA
TOF/TOF Mass Spectrometer

Alan G. Marshall, Florida State University, USA
Advances in FT-ICR MS Technology for Biological Molecules

Vicki H. Wysocki, Ohio State University, USA
Two Approaches to Improving Protein Identification by MS/MS

09:20—09:40
Coffee Break

Promenade
11:00—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
14:00—16:00
Workshop 1

Mesa A-B
John R. Engen, Northeastern University, USA
Probing Protein Dynamics with Hydrogen Exchange and Mass Spectrometry

Feng Zhong, MDS Sciex, Canada
A Novel PTM Discovery Method Using a Hybrid Linear Quadruple Ion Trap Mass Spectrometer

Yingming Zhao, University of Texas Southwestern Medical Center, USA
Proteomic Analysis of O-GIcNAc Modified Proteins

Michail A. Alterman, Food and Drug Administration, USA
Qualitative and Quantitative Maldi Tof-Based Proteomic Approach to the Profiling of Cytochrome P450 Isozymes

Brandon T. Ruotolo, University of Michigan, USA
Biomolecule Imaging Mass Spectrometry Based on MALDI-Ion Mobility-TOFMS

* Ansgar Brock, Genomics Institute, Novartis Research Foundation, USA
An Intelligent Approach for the Bootstrapping of Proteomes by Multidimensional LC MALDI QFT-ICR MS

16:30—17:00
Coffee & Snacks Available

Promenade
17:00—19:00
Technology II
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Richard D. Smith, Pacific Northwest National Laboratory, USA

Donald Douglas, University of British Colmbia, Canada
Linear Ion Traps in Mass Spectrometry

Luke V. Schneider, Target Discovery, Inc., USA
Differential Display on System Biological Research

Michael Senko, Thermo Electron Corporation, USA
Acquisition Strategies for Proteomic Analysis with a Hybrid Linear Ion Trap/Fourier Transform Mass Spectrometer

19:00—20:00
Social Hour

Mesa C
19:30—22:00
Poster Session 1

Mesa C

MONDAY, FEBRUARY 16

07:00—08:00
Breakfast

Chamisa
08:00—09:25
Applications of Mass Spectrometry: DNA
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Stephen Naylor, Beyond Genomics, USA

Charles R. Cantor, Sequenom Inc., USA
Nucleic Acid Analysis by High Throughput Automated Mass Spectrometry

David C. Muddiman, North Carolina State University, USA
Nucleic Acid Analysis Using High Field FT-ICR Mass Spectrometry

Kevin R. Ramkissoon, University of North Carolina at Chapel Hill, USA
Short Talk: Comparative Proteomic Analysis of Adaptive Evolution in Bacteria

09:25—09:45
Coffee Break

Promenade
09:45—11:00
Application of Mass Spectrometry Technology: Protein Expression
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
Richard D. Smith, Pacific Northwest National Laboratory, USA
Comprehensive Proteomices Using Nano-Scale Separations and FTICR Mass Spectrometry

Rudolf H. Aebersold, Institute of Molecular Systems Biology, ETH Zürich, Switzerland
Quantitative Proteomics: Current Status, Challenges and New Directions

11:00—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
14:00—16:00
Workshop 2

Mesa A-B
Jason D. Hoffert, NHLBI, National Institutes of Health, USA
Analysis of Inner Modullary Collecting Duct Protein

Megan R. Jones, University of Washington, USA
Protein Identification in Barrett’s Esophagus through LCQ/Mass Spectrometry

Jeffrey R. Johnson, University of California, San Francisco, USA
Targeted Proteomic Analysis of P. falciparum Asexual-Stage Antigens Reveals a Novel Multigene Family of Maurer’s Cleft Membrane Proteins

* Anna T. Neill, University of California, San Diego, USA
Tandem MS Analysis and an Emerging Genome: The Sea Urchin Sperm Plasma Membrane Proteome

Patrick A. Everley, Harvard Medical School, USA
Quantitative Proteomics: Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) as a Tool for Prostate Cancer Research

Brian D. Halligan, Medical College of Wisconsin, USA
Alternative Approaches to Peptide Identification from MS Data

16:30—17:00
Coffee & Snacks Available

Promenade
17:00—19:00
Application of Mass SpectrometryTechnology: Protein Expression
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Rudolf H. Aebersold, Institute of Molecular Systems Biology, ETH Zürich, Switzerland

Catherine Fenselau, , USA
Isotope Labeling Studies of Acquired Drug Resistance

David M. Lubman, University of Michigan, USA
2-D Liquid Mapping of a Cancer Cell Lysates

Robert T. Kennedy, University of Michigan, USA
In vivo Monitoring and Discovery of Neurotransmitters

Kimberly A. Lee, Cell Signaling Technology, USA
Short Talk: Immunoaffinity Profiling of Tyrosine Phosphorylation

19:00—20:00
Social Hour

Mesa C
19:30—22:00
Poster Session 2

Mesa C

TUESDAY, FEBRUARY 17

07:00—08:00
Breakfast

Chamisa
08:00—09:20
Application of Mass Spectrometry
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Catherine E. Costello†, Boston University School of Medicine, USA

Richard M. Caprioli, Vanderbilt University Medical Center, USA
Tissue Imaging and Profiling of Proteins by Mass Spectrometry for Discovery in Clinical and Biological Research

Nikolina Babic, University of Chicago, USA
Short Talk: The Effect of High Density Lipoproteins on Protein Expression in Rat Myoblast Cell Lines

Silvia Cermelli, Fred Hutchinson Cancer research Center, USA
Short Talk: Molecular Motor-Based Cargo Transport: A Proteomic Study

09:20—09:40
Coffee Break

Promenade
09:40—11:00
Protein Structure and Modifications
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
Carol V. Robinson, University of Oxford, UK
Studying Protein Complexes Using Mass Spectrometry

Natalie G. Ahn, University of Colorado, USA
Studying Protein Phosphorylation in Signal Transduction Pathways

Robert L. Hettich, Oak Ridge National Laboratory, USA
Short Talk: Mass Spectrometric Characterization of Protein Complexes from Rhodopseudomonas palustris

11:00—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
14:00—16:00
Workshop 3

Mesa A-B
Michael A. Freitas, Ohio State University, USA
Cracking the Histone Code: A Mass Spectrometry Based Approach for the Determination of Histone Modifications

* David L. Tabb, Oak Ridge National Laboratory, USA
Sequence Tagging Algorithms Enable Comprehensive Post-Translational Modification Analysis of Proteomic Tandem Mass Spectra

Sean A. Beausoleil, Harvard Medical School, USA
Phosphopeptide Detection by a Data-Dependent, Neutral-Loss Driven MS3 Scan Using Ion Trap Mass Spectrometry

Yun Han, University of California, Los Angeles, USA
Phosphorylation Profiling of Cancer Using Mass Spectrometry

Huang-Chun Tseng, Harvard Medical School, USA
Phosphoproteomic Analysis of Cellular Microtubule-Associated Proteins Using a Novel Solid-Phase Capture-Release-Tag Chemistry

Majbrit Hjerrild, Glostrup Hospital, Denmark
Neural Network and Mass Spectrometry Analysis for Identification of Protein Kinase A Phosphorylation Sites

16:30—17:00
Coffee & Snacks Available

Promenade
17:00—19:00
Applications of Mass Spectrometry Technology: Protein Modifications
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Carol V. Robinson, University of Oxford, UK

Steven P. Gygi, Harvard Medical School, USA
New Age Proteomics for the Study of Protein Ubiquitination

Neil L. Kelleher, Northwestern University, USA
Realizing the Potential of Q-FTMS for Top Down Proteomics of Yeast in Controlled Oxygen Environments

Michael MacCoss, University of Washington, USA
Measurement of Stable Isotope Labeled Peptides by Mass Spectormetry: Limitations, Solutions and Applications

Irwin Jack Kurland, Albert Einstein College of Medicine, USA
Short Talk: Metabolomic Determination of the Optimally Adapted versus Maladapted Glucose Metabolic Network

19:00—20:00
Social Hour

Mesa C
19:30—22:00
Poster Session 3

Mesa C

WEDNESDAY, FEBRUARY 18

07:00—08:00
Breakfast

Chamisa
08:00—11:30
Application of Mass Spectrometry Technology: Metabolomics I
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Neil L. Kelleher, Northwestern University, USA

Bernhard O. Palsson, University of California, San Diego, USA
Keynote: Metabolomics

Dayan B. Goodenowe, Phenomenome Discoveries Inc., Canada
Comprehensive Metabolomics: Analytical and Bioinformatic Challenges

Stephen George Oliver, Cambridge University, UK
Capture, Interpretation and Integration of MS Data for Proteomics and Metabolomics

Robert C. Murphy, University of Colorado Denver, USA
Mass Spectrometry of Lipids: A Diverse Family Regulating Cellular Function

Cecil R. Pace-Asciak, Hospital for Sick Children, Canada
Short Talk: LCMSMS Profiling of Prostaglandins and Related Eicosanoids

Peter Sjövall, SP Swedish National Testing and Research Institute, Sweden
Short Talk: High-Resolution Imaging of Membrane Lipids in Single Cells and Tissue by Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS)

09:20—09:40
Coffee Break

Promenade
16:30—17:00
Coffee & Snacks Available

Promenade
17:00—19:15
Application of Mass Spectrometry Technology: Metabolomics II
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Vicki H. Wysocki, Ohio State University, USA

Catherine E. Costello, Boston University School of Medicine, USA
Analysis of Biological Molecules Using Mass Spectrometry

Richard N. Trethewey, Metanomics GmbH, Germany
Metabolite Profiling: High Throughput Mass Spectrometry for Discovery and Development

Jonathan V. Sweedler, University of Illinois at Urbana-Champaign, USA
How Small Can We Go: Measuring the Neuropeptides in Single Cells to Single Organelles

Michael MacCoss, University of Washington, USA
For

Christine C. Wu, University of Colorado Health Sciences Center, USA
Shotgun Proteomic Analysis of Membrane Proteins in Mammalian Tissue Samples

19:45—20:45
Social Hour

Mesa C
20:00—23:00
Entertainment

Mesa C

THURSDAY, FEBRUARY 19

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13GM070004-01




We gratefully acknowledge additional support for this conference from:


Cell Signaling Technology, Inc.

Advion BioSciences, Inc.


Cell Signaling Technology, Inc.
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676