Eldorado Hotel & Spa Floorplan

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This meeting took place in 2006



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Molecular Mechanisms of Cardiac Disease and Regeneration (C3)


Organizer(s) Stefanie Dimmeler and Michael D. Schneider
February 19—24, 2006
Eldorado Hotel & Spa • Santa Fe, New Mexico USA
Abstract Deadline: Oct 19, 2005
Late Abstract Deadline: Nov 10, 2005
Scholarship Deadline: Oct 19, 2005
Early Registration Deadline: Dec 19, 2005

Supported by The Director's Fund

Summary of Meeting:
Inadequate tissue perfusion and defects in the functional activity of cardiac myocytes are the leading cause of death in the Western world. This meeting will provide a comprehensive overview of novel developments in cardiovascular sciences and attempts to enforce interaction between cardiac and vascular areas. The first part of the meeting will focus on the regulation of cardiac development and vessel formation both in embryonic development as well as in the adult organism. Signaling cascades regulating cardiac remodeling and cardiomyopathy will be discussed in the second part. Finally, novel strategies for vessel repair and cardiac regeneration including potential insights from stem-cell-derived cardiomyocytes, and cell-based therapies, will be presented. As aging is a major risk factor for cardiovascular disease a special session will focus on the molecular determinants of aging and its role in cardiac diseases.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, FEBRUARY 19

15:00—19:30
Registration

Zia Concourse
18:30—19:30
Refreshments

Sunset Room
19:30—21:30
Keynote Session
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Stefanie Dimmeler, University of Frankfurt, Germany

Randall T. Moon, University of Washington School of Medicine, USA
Wnt Signaling in Disease and Therapies

Eric N. Olson, University of Texas Southwestern Medical Center, USA
Transcriptional Control of Muscle Cell Hypertrophy and Differentiation


MONDAY, FEBRUARY 20

07:00—08:00
Breakfast

Eldorado Court
08:00—11:15
Cardiovascular Development: Myogenesis and Morphogenesis
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Eric N. Olson, University of Texas Southwestern Medical Center, USA

Mark Mercola, Stanford University, USA
Cardiac Lineage Determination in Embryos and ES Cells

Brian D. Dynlacht, New York University School of Medicine, USA
Regulatory Networks for Myogenesis

Giulio Cossu, Stem Cell Research Institute, Italy
Isolation and Characterization of Post-natal Cardiac Mesoangioblasts with High Cardiac Differentiation Potency

Deepak Srivastava, Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
Role of microRNAs during cardiac progenitor differentiation and cardiogenesis

Ian C. Scott, Hospital for Sick Children, Canada
Short Talk: Novel Role for the Peptide Ligand Apelin in Cardiovascular Development

Kory Lavine, Washington University School of Medicine, USA
Short Talk: Hedgehog Signaling Represents a Novel Therapeutic Target for Coronary Neo-Angiogenesis and Is Essential for Coronary Vascular Development

09:20—09:40
Coffee Break

Zia Concourse
11:15—13:00
Poster Setup

Sunset Room
13:00—22:00
Poster Viewing

Sunset Room
16:00—17:00
Workshop: NHLBI Support: What Every Investigator Needs to Know

Anasazi Ballroom
* Elizabeth G. Nabel, Brigham & Womens Hospital, USA
Fostering the Independence of New Investigators: NHLBI initiatives

Stephen C. Mockrin, NHLBI, National Institutes of Health, USA
NHLBI and NIH Programs in Cell-based Therapeutics

Sonia I. Skarlatos, NHLBI, National Institutes of Health, USA
NHLBI Research Training and Early Career Development Opportunities

16:45—17:00
Coffee Available

Zia Concourse
17:00—19:00
Angiogenesis and Vessel Remodeling
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Didier Stainier, Max Planck Institute for Heart and Lung Research, Germany

Elizabeth G. Nabel, Brigham & Womens Hospital, USA
Vascular Proliferation and Inflammation: Lessons learned from Genetic Diseases

Jonathan A. Epstein, University of Pennsylvania, USA
Class 1 HDAC Function and Cardiac Hypertrophy

Anne C. Eichmann, Yale University School of Medicine, USA
Neural Guidance Receptors in Angiogenesis

19:00—20:00
Social Hour with Lite Bites

Eldorado Court/Sunset Room
19:30—22:00
Poster Session 1

Sunset Room

TUESDAY, FEBRUARY 21

07:00—08:00
Breakfast

Eldorado Court
08:00—11:15
Signal Transduction in Hypertrophy and Heart Failure
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Deepak Srivastava, Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA

Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
ERK1/2 Signaling is not Necessary for Cardiac Hypertrophy in Vivo

Gabriele Grenningloh, School Polytechanical Federale de Lausanne, France
Protein Kinases in Cardiac Hypertrophy and Remodeling

Richard N. Kitsis, Albert Einstein College of Medicine, USA
ARC, a Multifunctional Repressor of Multiple Cell Death Pathways

Seigo Izumo, Takeda Pharmaceutical Company, Japan
Novel Strategies for the Treatment of Heart Failure

Joost Leenders, Academic Medical Center, Netherlands
Short Talk: Kr├╝ppel-Like Factor 15 is a Novel Transcriptional Regulator of Cardiac Hypertrophy Regulated by TGF-Beta

Thierry Pedrazzini, University of Lausanne Medical School, Switzerland
Short Talk: Notch Pathways Control Cardiogenesis in Undifferentiated Cardiac Precursors and are Crucial for Maintaining Cardiac Integrity in the Adult Heart

09:20—09:40
Coffee Break

Zia Concourse
11:00—13:00
Poster Setup

Sunset Room
13:00—22:00
Poster Viewing

Sunset Room
16:30—17:00
Coffee Available

Zia Concourse
17:00—19:00
Mechanisms of Cardiomyopathy and Heart Failure
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Seigo Izumo, Takeda Pharmaceutical Company, Japan

Christine E. Seidman, Harvard Medical School, USA
Genetic Mechanisms of Cardiomyopathy

Elizabeth M. McNally, Northwestern University, USA
The Dystrophin Sarcoglycan Complex in Cardiomyopathy

Kenneth R. Chien, Karolinska Institutet, Sweden
Islet-1 Cardiovascular Progenitors in Development and Disease

19:00—20:00
Social Hour with Lite Bites

Eldorado Court/Sunset Room
19:30—22:00
Poster Session 2

Sunset Room

WEDNESDAY, FEBRUARY 22

07:00—08:00
Breakfast

Eldorado Court
08:00—11:00
Stem/Progenitor Cells for Cardiac Repair
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
Thomas Eschenhagen, University Medical Center Hamburg-Eppendorf, Germany
Embryonic Stem Cells for Tissue Engineering

Stefanie Dimmeler, University of Frankfurt, Germany
Endothelial Progenitor Cells in Neovascularization and Cardiac Repair

* Douglas W. Losordo, Caladrius Biosciences, Inc., USA
Intramyocardial transplantation of autologous CD 34+ Stem CElls for Intractable Ischemia

Victor J. Dzau, Duke University Medical Center, USA
Paracrine Hypothesis of Stem Cells

Annie Bourdeau, Embassy of Canada, Thailand
Short Talk: Modulation of Bone Marrow-Derived Stem Cell Activity by TC-PTP

09:20—09:40
Coffee Break

Zia Concourse
11:00—13:00
Poster Setup

Sunset Room
13:00—22:00
Poster Viewing

Sunset Room
16:30—17:00
Coffee Available

Zia Concourse
17:00—19:00
Embryonic and Adult Stem Cell Plasticity
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Jonathan A. Epstein, University of Pennsylvania, USA

Robert J. Schwartz, Texas A&M University, USA
SRF, a Mesoderm Factor Required for the Formation of Embryonic Cardiac and Smooth Muscle Lineages

Naohiro Terada, University of Florida, USA
Signals and Scaffolds Controlling the Fate of Embryonic Stem Cell Differentiation

Michael D. Schneider, Imperial College London, UK
Cardiopoeisis: Cardiac Myocyte creation by adult and Embryonic Stem Cell

19:00—20:00
Social Hour with Lite Bites

Eldorado Court/Sunset Room
19:30—22:00
Poster Session 3

Sunset Room

THURSDAY, FEBRUARY 23

07:00—08:00
Breakfast

Eldorado Court
08:00—11:15
Aging and Other Determinants of Cardiac and Vascular Repair
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Nadia A. Rosenthal, The Jackson Laboratory, USA

Margaret A. Goodell, Baylor College of Medicine, USA
Aging in Stem Cells

Kenneth Walsh, Boston University School of Medicine, USA
Regulation of Physiological and Pathological heart Growth (adipokines and the heart)

Andreas M. Zeiher, University Frankfurt, Germany
Clinical Cell Therapy: Determinants of Successful Treatment

Rolf Bodmer, Sanford-Burnham Medical Research Institute, USA
The Failing fly Heart f: Drosophila as a Model for Congenital Heart Disease and Aging

Didier Stainier, Max Planck Institute for Heart and Lung Research, Germany
Cardiac Development and Function: Forward Genetics and Imaging

09:20—09:40
Coffee Break

Zia Concourse
16:30—17:00
Coffee Available

Zia Concourse
17:00—19:00
Stem Cell Recruitment and Augmentation
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Michael D. Schneider, Imperial College London, UK

Issei Komuro, Tokyo University Graduate School, Japan
Mechanism of Angiogenesis in Ischemic Limb

Nadia A. Rosenthal, The Jackson Laboratory, USA
Enhancing Regeneration of the Mammalian Heart

Steven J. Kattman, , USA
Short Talk: Specification of Multipotential Cardiovascular Progenitor Cells During ES cell Differentiation

19:00—20:00
Social Hour with Lite Bites

Eldorado Court/Sunset Room
20:00—23:00
Entertainment

Eldorado Court/Sunset Room

FRIDAY, FEBRUARY 24

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13 HL082183-01




We gratefully acknowledge additional support for this conference from:

Boehringer Ingelheim Pharmaceuticals, Inc. Novartis Institutes for BioMedical Research

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


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If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

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Phone:+1 970-262-2676