Eldorado Hotel & Spa Floorplan

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This meeting took place in 2007


Here are the related meetings in 2018:
Immunological Memory: Innate, Adaptive and Beyond (X1)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Immunologic Memory (C4)


Organizer(s) Robert A. Seder, Susan L. Swain, Rafi Ahmed and Antonio Lanzavecchia
March 3—8, 2007
Eldorado Hotel & Spa • Santa Fe, New Mexico USA
Abstract Deadline: Nov 3, 2006
Late Abstract Deadline: Dec 4, 2006
Scholarship Deadline: Nov 3, 2006
Early Registration Deadline: Jan 3, 2007

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation

Summary of Meeting:
Immune memory has a critical role in mediating protection against infections as well as potentiating allergic and autoimmune diseases. Hence a thorough understanding of the molecular and cellular mechanisms regulating adaptive memory immunity will have potentially important clinical application. Recent developments in how the innate immune response influences adaptive immunity combined with better methods to characterize the phenotype, magnitude and functional quality of such responses have substantially improved our understanding in this area. Major problems still relate to difficulties in eliciting long-term T cell responses with current vaccines in humans. The goals of the meeting will be to focus on basic mechanisms regarding how T and B cells are programmed to elicit and sustain immunity. The program is designed to integrate information from both mouse and humans studies to encompass all relevant areas related to control of memory T and B cell responses. In summary, this meeting should greatly enhance translational research that will impact vaccines and interventions for infectious disease, cancer and autoimmune/allergic diseases.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SATURDAY, MARCH 3

15:00—19:30
Registration

North Concourse
18:30—19:30
Refreshments

Pavilion
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
Peter C. Doherty, University of Melbourne, Australia
Thinking About T Cell Memory


SUNDAY, MARCH 4

07:00—08:00
Breakfast

Pavilion
08:00—11:00
CD4+ T Cell Memory
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Marc K. Jenkins, University of Minnesota Medical School, USA
Enumeration of Polyclonal Antigen-Specific CD4+ T Cells in Naïve and Immunized Individuals.

Charles D. Surh, La Jolla Institute for Allergy and Immunology, USA
Regulation of Memory CD4+ T cell Selection and Homeostasis

Robert A. Seder, NIAID, National Institutes of Health, USA
The Quality of a Th1 Response Determines Protection

Laurie H. Glimcher, Dana-Farber Cancer Institute, USA
Inflammation and Immunity Intersect at XBP-1

Rafick-Pierre Sékaly, Case Western Reserve University, USA
Short Talk: Survival Pathways of Memory T Cells: Role of FOXO3a

09:20—09:40
Coffee Break

Pavilion
11:00—13:00
Poster Setup

Pavilion
13:00—22:00
Poster Viewing

Pavilion
14:30—16:30
Workshop 1: Immunodominance and T Cell Repertoire

Anasazi Ballroom
* Liisa K. Selin, University of Massachusetts Medical School, USA

Ann B. Hill, Oregon Health & Science University, USA
The CD8 T Cell Response to Murine Cytomegalovirus Undergoes a Dramatic Alteration in Immunodominance Hierarchy Between Acute and Chronic Infection

David Price, Cardiff University School of Medicine, UK
Public Clonotype Usage in Virus-Specific CD8+ T Cell Populations: Mechanisms of TCR Sharing and Biological Implications

Vanessa Venturi, University of New South Wales, Australia
Methods for Comparing Samples of the T Cell Receptor Repertoire

Julie Leignadier, LICR, University of Laussane, Switzerland
TCR Signals Regulate the Generation and Maintenance of Memory T Cells

Scott N. Mueller, University of Melbourne, Australia
Closing the Door on Immune Responses: Regulation of Homeostatic Chemokines in Lymphoid Organs

David J. Topham, University of Rochester Medical Center, USA
The Alpha1 Beta1 Integrin VLA-1 and TNF-Alpha Protect Influenza Specific CD8+ Effector T Cells from Apoptosis during Acute Infection

16:30—17:00
Coffee Available

Pavilion
17:00—19:00
B Cell Memory
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Michael G. McHeyzer-Williams, The Scripps Research Institute, USA
Lymphoid Retention of Memory TFH Cells

Shane Crotty, La Jolla Institute for Allergy and Immunology, USA
Short Talk: Deterministic Linkage between CD4 T Cell and B Cell Specificities to a Large Viral Pathogen

Andreas Radbruch, Deutsches Rheuma-Forschungszentrum, Berlin, Germany
Selecting Plasma Cells to Memory

Claude-Agnès Reynaud, Necker-Paris Medical School, France
Repertoire diversification discriminates IgM+IgD+CD27+ from switched memory B cells in humans

19:00—20:00
Social Hour with Lite Bites

Pavilion
19:30—22:00
Poster Session 1

Pavilion

MONDAY, MARCH 5

07:00—08:00
Breakfast

Pavilion
08:00—11:00
Innate Immunity
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Bali Pulendran, Emory University, USA
Modulating Vaccine Responses with Innate Immunity

Pratima Krishna-Suvas, University of Tennessee, USA
Short Talk: Generation and Maintenance of Antigen-Specific CD8 T Cells in the Vaginal Mucosa Following Systemic Versus Mucosal Routes of Immunization

Thandi M. Onami, Bill & Melinda Gates Foundation, USA
Short Talk: Generation and Maintenance of Antigen-Specific CD8 T Cells in the Vaginal Mucosa Following Systemic Versus Mucosal Routes of Immunization

Judith N. Mandl, National Institutes of Health, USA
Short Talk: Differences in the Induction of Cellular Immune Responses to Specific Virus Infections in Rhesus Macaques and Sooty Mangabeys Relates to Altered Innate Signalling Via Toll-Like Receptor 7 and 9

Albert S. Bendelac, University of Chicago, USA
'Natural Memory' NKT cells

Christine A. Biron, Brown University, USA
Innate Immunity during Viral Infections

09:20—09:40
Coffee Break

Pavilion
11:00—13:00
Poster Setup

Pavilion
13:00—22:00
Poster Viewing

Pavilion
14:30—16:30
Workshop 2: Aging and Memory

Anasazi Ballroom
* Richard J. Hodes, NIA, National Institutes of Health, USA

* Laura Haynes, University of Connecticut Health Center, USA
The Effect of Aging on Primary and Memory Responses of CD4 T Cells

Carl E. Ruby, Rush University Medical Center, USA
OX40-Mediated Survival of Antigen-Activated CD4 T Cells Requires IL-12 Signaling

C. John Luckey, Brigham and Women's Hospital, USA
IL-18 Receptor is Required for Effector CD8+ T Cells to Survive the Contraction Phase of an Immune Response and Become Long-Lived Memory Cells

David Hildeman, Cincinnati Children's Hospital, USA
Contraction of CD4+ T Cell Responses is not Controlled by Limiting Amounts of IL-7

Vilma Decman, FlowMetric, Inc., USA
Qualitative Changes in Anti-Viral CD8 T Cell Responses with Aging

Susmit Suvas, Oakland University, USA
Functional Significance of PD-1 Expression on Aging T Cells

Eric T. Clambey, University of Colorado Denver, USA
Altered CD8 Memory T cells Homeostasis in Aging: Multiple Paths to CD8 Clonal Expansions

16:30—17:00
Coffee Available

Pavilion
17:00—19:00
Epigenetic and Transcriptional Regulation
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Steven L. Reiner, Columbia University, USA
Making Daughter T Cells Different During Immunity

Kathryn L. Calame, Columbia College of Physicians and Surgeons, USA
Transcriptional Control in Memory for B and T Lymphocytes

Susan L. Swain, University of Massachusetts Medical School, USA
Effector and Memory CD4 T Cell Protection in Influenza

Tania H. Watts, University of Toronto, Canada
Short Talk: A Critical Role for TNFR Associated Factor 1 and Bim Down Regulation in CD8 Memory T Cell Survival

19:00—20:00
Social Hour with Lite Bites

Pavilion
19:30—22:00
Poster Session 2

Pavilion

TUESDAY, MARCH 6

07:00—08:00
Breakfast

Pavilion
08:00—11:30
CD8+ T Cell Memory
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
Michael J. Bevan, HHMI/University of Washington, USA
Role of CD4+ T Cells in Sustaining CD8+ T Cell Memory

* David L. Woodland, Keystone Symposia on Molecular and Cellular Biology, USA
Heterogeneity of the Memory CD8+ T Cell Response to Respiratory Virus Infections

Ananda W. Goldrath, University of California, San Diego, USA
Short Talk: A Novel Role for Id2 in the Regulation of CD8+ T Cell immunity

Susan M. Kaech, Yale University School of Medicine, USA
Regulation of Memory CD8 T Cell Precursor Formation by T-bet and Inflammatory Cytokines

Raymond M. Welsh, University of Massachusetts Medical School, USA
Plasticity of CD8+ T Cell Responses following Heterologous Viral Infections

Stephen P. Schoenberger, La Jolla Institute for Allergy and Immunology, USA
Programming of CD8+ T Cell Responses: Tune In, Turn On, or Drop Out

09:20—09:40
Coffee Break

Pavilion
11:30—13:00
Poster Setup

Pavilion
13:00—22:00
Poster Viewing

Pavilion
14:30—16:30
Workshop 3: Animal Models of Vaccines

Anasazi Ballroom
* Dan H. Barouch, Harvard Medical School/Beth Israel Deaconess Medical Center, USA

* Adrian V. S. Hill, Jenner Institute, University of Oxford, UK

Ross M. Kedl, University of Colorado Denver, USA
Combined-TLR/CD40 Immunization Generates, and Rescues, CD4-Independent CD8+ T Cell Memory

Pratima Krishna-Suvas, University of Tennessee, USA
Generation and Maintenance of Antigen-specific CD8 T Cells in the Vaginal Mucosa following Systemic versus Mucosal Routes of Immunization

Tara Marlene Strutt, University of Central Florida, USA
Heterosubtypic CD4 and CD8 T cell Immunity Induced by CAV A/Alaska Protects Against the Inflammatory Cell Influx Associated with Lethal Virus Challenge

Denise Y. L. Teoh, SERC, A*STAR, Singapore
Programming CD8 T cells: Impact of immunization route on development of the CD8 T cell response and protective immunity

Gabrielle T. Belz, Walter and Eliza Hall Institute of Medical Research, Australia
Optimal Expansion of Naïve and Memory CD8+ Cells in vivo Regulated by Divergent Mechanisms

16:30—17:00
Coffee Available

Pavilion
17:00—19:15
Regulatory Aspects of Memory Immunity
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Harald von Boehmer, Harvard Medical School, USA
Treg Induction and T Cell Memory

Yiping Yang, Duke University Medical Center, USA
Short Talk: The Development and Function of “Memory” Regulatory T Cells Following Viral Infection

Yasmine Belkaid, NIAID, National Institutes of Health, USA
Influence of CD25+ Regulatory T Cells on Th1 Immunity

Linda M. Bradley, Sanford-Burnham Medical Research Institute, USA
Short Talk: CD44 Regulates Effector Cell Survival and the Generation of Memory in CD4 Cells

Richard J. Hodes, NIA, National Institutes of Health, USA
Aging and the Immune System: Discoveries and Challenges

19:15—20:15
Social Hour with Lite Bites

Pavilion
19:30—22:00
Poster Session 3

Pavilion

WEDNESDAY, MARCH 7

07:00—08:00
Breakfast

Pavilion
08:00—11:15
Homeostasis and Memory
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
* Philippa C. Marrack, HHMI/National Jewish Health, USA
Viral Proteins which Interfere with Lymphocyte Death

John T. Harty, University of Iowa, USA
Querying the CD8 T cell Response Program

Leo Lefrançois, University of Connecticut Health Center, USA
Imaging the Endogenous T Cell Response to Infection

Benedita Rocha, INSERM U591, France
The Analysis of of Single-Cells in CD8 Responses Reveals a Complex Effector Gene Expression with the Generation of Three Different Effector Types

Stephen C. Jameson, University of Minnesota Medical School, USA
Helping Homeostatic Memory CD8 T cells

09:20—09:40
Coffee Break

Pavilion
14:30—16:30
Workshop 4: T Cell Immunity and Chronic Infection

Anasazi Ballroom
* Louis J. Picker, Oregon Health & Science University, USA
Title to be Determined

John F. McDyer, John Hopkins University, USA
Acquisition of CMV-specific Effector T Cell Memory in the Airways and Blood During Primary Infection in Lung Transplant Recipients

Lydie Trautmann, US Military HIV Research Program, USA
Upregulation of PD-1 Expression in HIV Specific CD8 T Cells Leads to Reversible Functional Exhaustion

Angela Shaulov Kask, University of Washington, USA
Sustained Expansion of CD8 T Cells Requires Simultaneous Exposure to Antigen and Inflammation in vivo

Vandana Kalia, Seattle Children's, USA
Mechanisms Regulating Memory CD8 T Cell Differentiation

Kathy Cho, Astellas Pharma US, USA
Determining the Role of Murine Cytomegalovirus (MCMV) Viral Activity in CD8+ T Cell Memory Inflation and Tem Phenotype during Latent Infection

Kathleen Anderson, Columbus Children's Hospital, USA
Persistent Viral Infection Results in a Delayed and Dysfunctional Memory CD4+ T Cell Response

John R. Teijaro, The Scripps Research Institute, USA
Distinct Protective Capacities of Lymphoid and Non-Lymphoid Memory CD4 T Cell to Influenza Challenge

16:30—17:00
Coffee Available

Pavilion
17:00—19:00
Vaccination
Meeting has ended...abstracts no longer viewable online.

Anasazi Ballroom
Rafi Ahmed, Emory University School of Medicine, USA
Immunological Strategies for Treating Chronic Infections

Antonio Lanzavecchia, Institute for Research in Biomedicine, Switzerland
Title to be Determined

* Richard A. Koup, NIAID, National Institutes of Health, USA
Prime-Boost Vaccination Against HIV Infection

19:00—20:00
Social Hour with Lite Bites

Pavilion
20:00—23:00
Entertainment

Pavilion

THURSDAY, MARCH 8

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 U13 AI60000-01




National Institutes of Health

Grant No. 1R13AI072830-01




We gratefully acknowledge additional support for this conference from:

Bill & Melinda Gates Foundation JDRF

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