Beaver Run Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2007



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Epigenetics: Regulation of Chromatin Structure in Development and Disease (D3)


Organizer(s) Barbara Panning and Hiten D. Madhani
April 11—16, 2007
Beaver Run Resort • Breckenridge, Colorado USA
Abstract Deadline: Dec 11, 2006
Late Abstract Deadline: Jan 15, 2007
Scholarship Deadline: Dec 11, 2006
Early Registration Deadline: Feb 12, 2007

Summary of Meeting:
Epigenetic regulatory mechanisms provide cells with transcriptional memory, allowing cells to stably maintain expression patterns for many divisions, and developmental flexibility, facilitating programmed alterations in gene expression during embryogenesis. Recent developments indicate that surprisingly dynamic modifications in chromatin structure are employed to regulate gene expression and have far-reaching consequences for cell fate decisions and normal and pathological development. Significant progress has been made in understanding the role of epigenetics in topics as diverse as cloning, cancer biology, genomic imprinting, development in plants and animals, and DNA repair. Similar molecules are employed by different organisms to affect chromatin structure and achieve epigenetic regulation. However the molecular mechanisms by which the changes in chromatin structure modulate gene expression remain mysterious. This Keystone Symposium on ‘Chromatin Structure in Development and Disease’ will bring together diverse fields, from basic studies in model organisms to medical research to biotechnology. The primary aim of the meeting will be to promote communication between diverse groups of epigenetic and chromatin researchers, facilitating cross dissemination of approaches to understanding these fascinating and medically important processes.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


WEDNESDAY, APRIL 11

15:00—19:30
Registration

Foyer
18:30—19:30
Refreshments

Foyer
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA
Epigenetics and Nuclear Reprogramming


THURSDAY, APRIL 12

07:00—08:00
Breakfast

Peaks 6 - 12
08:00—11:15
Histone Modifications 1: Making the Marks
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
Yang Shi, Children's Hospital Boston, Harvard Medical School, USA
Dynamic Regulation of Histone Methylation by Demethylases

Yi Zhang, HHMI/Harvard Medical School, Children's Hospital Boston, USA
Histone Demethylation by the JmjC Domain-Containing Proteins

* Brian D. Strahl, University of North Carolina at Chapel Hill, USA
Histone Modifications in RNA Polymerase II Transcription

Yifan Liu, Rockefeller University, USA
Short Talk: RNAi-Dependent H3 K27 Methylation is Required for Heterochromatin Formation and DNA Elimination in Tetrahymena

Alexander Tarakhovsky, Rockefeller University, USA
Histone Mimicry by Histone Methyltransferase G9a

Hengbin Wang, University of Alabama, Birmingham, USA
Short Talk: Regulation of Cell Cycle Progression and Gene Expression by H2A Deubiquitination

09:20—09:40
Coffee Break

Foyer
11:15—13:00
Poster Setup

Peaks 14 - 17
13:00—22:00
Poster Viewing

Peaks 14 - 17
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Histone Modifications 2: The Effectors
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
Robert E. Kingston, Massachusetts General Hospital, USA
Possible Roles in Silencing for piRNAs

Sarah C.R. Elgin, Washington University, USA
Heterochromatin Formation and Gene Silencing in Drosophila

Dinshaw J. Patel, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Combinatorial Readout of Histone Epigenetics Marks

Shiv I. S. Grewal, NCI, National Institutes of Health, USA
Heterochromatin: A Versatile Platform of the Genome

Masami Horikoshi, University of Tokyo, Japan
Short Talk: Structure and Functional Basis of the Histone Chaperone CIA/ASF1-Histone H3-H4 Complex

19:00—20:00
Social Hour with Lite Bites

Peaks 14 - 17
19:30—22:00
Poster Session 1

Peaks 14 - 17

FRIDAY, APRIL 13

07:00—08:00
Breakfast

Peaks 6 - 12
08:00—11:15
Non Coding RNAs
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
Danesh Moazed, Harvard Medical School, USA
Transcription and RNAi in Heterochromatin

Sundeep Kalantry, University of Michigan Medical School, USA
Short Talk: Xist RNA-Independent Initiation of Mouse Imprinted X-Chromosome Inactivation

Takashi Nagano, Babraham Institute, UK
Short Talk: The Air Non-Coding RNA Epigenetically Silences Transcription by Interacting with Chromatin at Specific Regions

John L. Rinn, University of Colorado, Boulder, USA
Short Talk: Epigenetic Regulation of the Human HOX Loci by Non-coding RNAs

Yota Murakami, Institute for Virus Research, Kyoto University, Japan
Short Talk: Determinants of the Fate of Non-Coding RNA Transcribed from RNAi-Dependent Heterochromatin in Fission Yeast

* Barbara Panning, University of California, San Francisco, USA
Xist RNA and Randomness

09:20—09:40
Coffee Break

Foyer
11:15—13:00
Poster Setup

Peaks 14 - 17
13:00—22:00
Poster Viewing

Peaks 14 - 17
16:30—17:00
Coffee Available

Foyer
17:00—19:00
DNA Methylation
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
Steven E. Jacobsen, University of California, Los Angeles, USA
DNA Methylation in Arabidopsis

* Marisa S. Bartolomei, University of Pennsylvania Perelman School of Medicine, USA
Epigenetic Regulation of H19 and Igf2 Imprinting

Timothy H. Bestor, Columbia University College of Physicians and Surgeons, USA
An Epigenetic Machine Interprets Histone H3K4 Methylation to Guide DNA Methylation

Matthew C. Lorincz, University of British Columbia, Canada
Short Talk: An Unmethylated 3’ Promoter-Proximan Region is Required for Efficient Transcription Initiation

19:00—20:00
Social Hour with Lite Bites

Peaks 14 - 17
19:30—22:00
Poster Session 2

Peaks 14 - 17

SATURDAY, APRIL 14

07:00—08:00
Breakfast

Peaks 6 - 12
08:00—11:15
Histone Variants
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
Ralph Scully, Beth Israel Deaconess Medical Center, USA
Histone H2AX-Associated Proteins MDC1, 53BP1 and BRCA1 in Recombination Control

Elizabeth M. Duncan, Stowers Institute for Medical Research, USA
Short Talk: Chromatin Remodeling during Murine ES Cell Differentiation

* Hiten D. Madhani, University of California, San Francisco, USA
Determinants of Promoter Chromatin Architecture

Steven Henikoff, Fred Hutchinson Cancer Research Center, USA
Epigenetic Patterns Generated by Histone Replacement

Karolin Luger, Colorado State University, USA
Histone Chaperones and Scavengers

Jason H. Brickner, Northwestern University, USA
Short Talk: Gene Recruitment to the Nuclear Periphery Confers Memory of Past Transcription

09:20—09:40
Coffee Break

Foyer
11:15—13:00
Poster Setup

Peaks 14 - 17
13:00—22:00
Poster Viewing

Peaks 14 - 17
16:30—17:00
Coffee Available

Foyer
17:00—19:15
Epigenetics and Disease 1
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
Terumi Kohwi-Shigematsu, Lawrence Berkeley National Laboratory, USA
Genome Organizer SATB1 in Breast Carcinogenesis

* Douglas Higgs, MRC Molecular Haematology Unit, UK
Progress Towards Understanding the Role of the ATRX Protein

Dennis R. Grayson, University of Illinois at Chicago, USA
Methylation and the Regulation of Reelin and GAD67 in Schizophrenia

Raman Nagarajan, GlaxoSmithKline, USA
Short Talk: Defects in MECP2 Expression and Epigenetic Regulation are Common in Autism Brain

Kyoko Yokomori, University of California, Irvine, USA
Short Talk: Specific Loss of Heterochromatin at D4Z4 Repeats in Facioscapulohumeral Dystrophy

19:15—20:15
Social Hour with Lite Bites

Peaks 14 - 17
19:30—22:00
Poster Session 3

Peaks 14 - 17

SUNDAY, APRIL 15

07:00—08:00
Breakfast

Peaks 6 - 12
08:00—11:00
Genomic Approaches
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
* Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Silent Running: RNA Interference and Heterochromatin in Plants and Fission Yeast

Jeffrey A. Jeddeloh, Roche NimbleGen, USA
Short Talk: Comparative Epigenetic Profiling Reveals Novel Cancer Biomarkers

Richard A. Young, Whitehead Institute for Biomedical Research, USA
TrxG and PcG Proteins in Vertebrate Development

Chia-Lin Wei, Genome Institute of Singapore, Singapore
Short Talk: Global Mapping of Histone K4 and K27 Trimethylation Patterns Reveal Distinct Compartments and Utilization of Human ESC Genome

Thomas G. Fazzio, University of Massachusetts Medical School, USA
Short Talk: Identification of Chromatin Regulators Required for Embryonic Stem Cell Self-Renewal using RNA Interference

Nevan J. Krogan, University of California, San Francisco, USA
E-MAP Analysis of Chromatin in S. cerevisiae

09:20—09:40
Coffee Break

Foyer
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Epigenetics and Disease 2
Meeting has ended...abstracts no longer viewable online.

Peaks 1 - 5
* Maarten Van Lohuizen, Netherlands Cancer Institute, Netherlands
Polycomb Repressors Controlling Stem Cell Fate: Implications for Cancer and Development

Moshe Szyf, McGill University, Canada
DNA Demethylation and Cancer; Therapeutic Implications

Harriet Karimi Kinyamu, NIEHS, National Institutes of Health, USA
Short Talk: Proteasome Inhibition Alters HIstone H3 Lysine Methylation Landscape to Modulate Hormone Regulated Gene Expression

Amar J. S. Klar, NCI, National Institutes of Health, USA
Regulation of DNA Strand/Chromatid Segregation in Mouse Cell Divisions

19:00—20:00
Social Hour with Lite Bites

Peaks 14 - 17
20:00—23:00
Entertainment

Peaks 14 - 17

MONDAY, APRIL 16

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 CA124284-01




We gratefully acknowledge additional support for this conference from:

CellCentric Ltd.
EMD Millipore

Rett Syndrome Research Foundation
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676