Capital Hotel Floorplan

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This meeting took place in 2007



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Frontiers in Gastrointestinal Cancer: Molecular Genetics, Inflammation, Early Detection and Therapy (T2)


Organizer(s) Qimin Zhan, Yang Ke, Xin Wei Wang, Raymond DuBois and Zongtang Sun
October 14—19, 2007
Capital Hotel • Beijing, China
Abstract Deadline: Jul 17, 2007
Late Abstract Deadline: Jul 17, 2007
Scholarship Deadline: Jun 14, 2007
Early Registration Deadline: Aug 14, 2007

In Collaboration with and Cosponsored by Chinese Academy of Medical Sciences and Peking University Health Science Center

Summary of Meeting:
Gastrointestinal (GI) malignancies account for a large fraction of human cancers. They are almost without exception incurable when gross metastases exist. Three of the 20 top leading causes of worldwide mortality are related to GI malignancies. For example, liver cancer is the third leading cause of worldwide cancer deaths and most of them (>79%) are in Asia. Liver and gastric cancers are the leading cause of cancer deaths in China. There is a strong need to discuss and develop a coherent strategy by joining efforts from both east and west to study GI malignancies. The Keystone Symposia is an excellent platform for a conference on GI malignancies because of its high scientific standard and impact. An in depth discussion of the interest in molecular epidemiology, GI cancer models, molecular diagnostic/prognostic, therapeutic strategies and cancer stem cells in the context of rapid development of these areas is therefore timely. The goals of this symposium are to bring together Academia, Government and Industry laboratories from Asia, North America and Europe working on gastroenterological malignancies, to exchange state-of-the-art and late-breaking discoveries, and to update consensus strategies in a fight against these malignancies.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, OCTOBER 14

15:00—19:00
Registration

Jinyun Foyer
18:00—19:00
Refreshments

Jinyun Foyer
19:00—19:15
Opening Remarks

Jinyun Ballroom
19:15—20:15
Keynote Session
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
Carlo M. Croce, Ohio State University, USA


MONDAY, OCTOBER 15

07:30—08:30
Breakfast

Coffee House
08:30—11:45
Biology and Genetics of GI Malignancies I
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Michael Karin, University of California, San Diego, USA

* Xiaodong Wang, National Institute of Biological Sciences, China

Joanna L. Groden, Ohio State University, USA
DNA Repair and Colon Cancer

Benjamin C.Y. Wong, University of Hong Kong, China
Stomach Cancer: Molecular Targets for Prevention and Treatment

Scott W. Lowe, Memorial Sloan Kettering Cancer Center, USA
Probing the genetics and biology of liver carcinoma using mouse models and RNA interference

Vincent W. Yang, Emory University, USA
Krüppel-Like Factors (KLFs) and Intestinal Tumorigenesis

Ursula Barbara Kurzik-Dumke, Institute of Medical Microbiology and Hygiene, Comparative Tumor Biology, Germany
Short Talk: Htid-1, the Human Homolog of the Drosophila Melanogaster l(2)tid Tumor Suppressor, is a Novel Physiological Ligand of APC Associated with Progression of Colorectal Cancer

Lin Yang, University of Texas, MD Anderson Cancer Center, USA
ZNF306, a Novel “Master Regulator” of Gene Expression, Drives Progression of Colorectal Cancers Unaltered for Commonly-mutated Genes

09:45—10:15
Coffee Break

Jinyun Foyer
12:00—13:00
Poster Setup

Jinyun Foyer
15:30—17:30
Poster Session 1

Jinyun Foyer
16:30—17:30
Coffee & Snacks Available

Jinyun Foyer
17:30—18:30
Evening Keynote Address
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Qimin Zhan, Chinese Academy of Medical Sciences, China

Xiaodong Wang, National Institute of Biological Sciences, China
Apoptosis and Cancer

18:30—19:45
Cancer Biology and Genetics of GI Malignancies II
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Xin Wei Wang, NCI, National Institutes of Health, USA

Qimin Zhan, Chinese Academy of Medical Sciences, China
The Cell Cycle Regulator in Malignant Development of Human Esophageal Cancer

Hong-Yang Wang, International Cooperation Laboratory on Signal Transduction, SMMU, China
Cell Signaling and Human Hepatocellular Carcinoma


TUESDAY, OCTOBER 16

07:30—08:30
Breakfast

Coffee House
08:30—11:45
Role of Microenvironment and Inflammation in GI Cancers I
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Raymond N. DuBois, Arizona State University, USA

Curtis C. Harris, NCI, National Institutes of Health, USA
Inflammation and Cancer: Interactions of the MicroRNA, p53 and Cytokine Pathways

Martin J. Blaser, New York University School of Medicine, USA
Oncogenic Pathways Related to Helicobacter pylori

Michael Karin, University of California, San Diego, USA
How Inflammation Affects Cancer Development and Progression: The IKK Complex and Beyond

Timothy C. Wang, Columbia University, USA
The Role of Inflammation and Bone Marrow Progenitor Cells in the Pathogenesis of Gastric Cancer

Anna Bigas, IDIBELL-Institut de Recerca Oncologica, Spain
Short Talk: Notch Cooperates with Beta-catenin to Activate a Specific Gene Program

Hiroyuki Marusawa, Kyoto University, Japan
Short Talk: Activation-induced Cytidine Deaminase Links Liver Inflammation to Human Hepatocarcinogenesis

09:45—10:15
Coffee Break

Jinyun Foyer
12:00—13:00
Poster Setup

Jinyun Foyer
23:30—13:30
Lunch

Coffee House
13:30—15:30
Workshop

Jinyun Ballroom
* Zongtang Sun, Chinese Academy of Medical Sciences, China

* Xiaodong Wang, National Institute of Biological Sciences, China

François Boudreau, University of Sherbrooke, Canada
Loss of Cathepsin L Activity Promotes Claudin-1 over Expression and Intestinal Neoplasia

Rachid A. Karam, MD Anderson Cancer Center, USA
The NMD RNA Surveillance Pathway Degrades Aberrant E-Cadherin Transcripts in Hereditary Diffuse Gastric Cancer

Giang Huong Nguyen, National Institutes of Health, USA
A Unique Inflammatory Gene Signature Associated with Reduced Survival in Esophageal Cancer

Hui Xiao, Institut Pasteur of Shanghai, China
The Regulatory Role of SIGIRR in Colonic Epithelial Homeostasis, Inflammation and Tumorigenesis

Ying Yang, Institute of Molecular Medicine, Peking University, China
Shp2 Suppresses the mT-induced Transformation by Inhibiting Stat3 and mTOR/S6K1 Signaling Pathways

Mi-Ock Lee, Seoul National University, South Korea
Hepatitis B Virus X Protein Induces the Expression of MTA1 and HDAC1, which Enhances Hypoxia Signaling in Hepatocellular Carcinoma Cells

Siina Junnila, University of Helsinki, Finland
Different Gastric Cancer Subtypes Exhibit Distinct Molecular Profiles by Gene Copy Number, Expression and Tissue Microarrays

15:30—17:30
Poster Session 2

Jinyun Foyer
16:30—17:30
Coffee & Snacks Available

Jinyun Foyer
17:30—19:30
Role of Microenvironment and Inflammation in GI Cancers II
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Snorri S. Thorgeirsson, National Institutes of Health, USA

Varda Rotter, Weizmann Institute of Science, Israel
Identification and Characterization “Gene Signatures” Involved in Cells Transformed in vitro

Hiroshi Ohshima, University of Shizuoka, Japan
Helicobacter pylori Infection, Oxidative and Nitrative Stress and Stomach Cancer


WEDNESDAY, OCTOBER 17

07:30—08:30
Breakfast

Coffee House
08:30—11:45
GI Cancer Epidemiology and Prevention I
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Curtis C. Harris, NCI, National Institutes of Health, USA

Yu-Tang Gao, Shanghai Cancer Institute, China
Gastrointestinal Cancer Incidence and Trends in China

Dongxin Lin, Chinese Academy of Medical Sciences & Peking Union Medical College, China
Genetic Polymorphisms and Risk of Gastroesophageal Cancer

Raymond N. DuBois, Arizona State University, USA
Colorectal Cancer Prevention: Molecular Targets

Yang Ke, Peking University, China
HPV and Esophageal Cancer

Wei-guo Zhu†, Peking University Health Sciences Center, China
Short Talk: A Correlation Exists between Numb and Notch1 Expression in Colorectal Cancer with Clinicopathological Parameters

Donghui Li, University of Texas, MD Anderson Cancer Center, Health Science Center, USA
Short Talk: Genetic Variations in Drug Metabolism and DNA Repair as Predictors for Clinical Outcomes of Pancreatic Adenocarcinoma

09:45—10:15
Coffee Break

Jinyun Foyer
12:00—13:00
Poster Setup

Jinyun Foyer
12:00—17:00
Optional Tour with Lunch

17:00—17:30
Coffee Available

Jinyun Foyer
17:30—19:30
GI Cancer Epidemiology and Prevention II
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Edison T. Liu, The Jackson Laboratory, USA

Thomas Ried, National Cancer Institute, National Institutes of Health, USA
Causes and Consequences of Chromosomal Aneuploidy in Colon Cancer

Gangqiao Zhou, Beijing Proteom Research Center, China
Genetic Susceptibility to Common Cancers of Chinese

Suet Yi Leung, University of Hong Kong, La Ka Shing Faculty of Medicine, Hong Kong
Microsatellite Instability in Hereditary and Sporadic Colorectal Cancer – Genetic and Epigenetic Mechanisms

19:30—20:30
Social Hour with Lite Bites

Jinyun Foyer
19:30—22:00
Poster Session 3

Jinyun Foyer

THURSDAY, OCTOBER 18

07:30—08:30
Breakfast

Coffee House
08:30—11:30
New Horizon in Early Detection and Therapies I
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Peter R. Galle, University of Mainz, Germany

Edison T. Liu, The Jackson Laboratory, USA
Systems Pharmacology: Cancer Therapeutics

Xin Wei Wang, NCI, National Institutes of Health, USA
Diagnostic and Prognostic Signatures of Liver Cancer

Zhao-You Tang, Fudan University, China
Liver Cancer Therapy at Liver Cancer Institute of Fudan University

Frederic Hollande, University of Melbourne, Australia
Short Talk: Inhibition of Beta-catenin/Tcf-4 and Notch After Progastrin-Targeting Reduces Growth and Drives Differentiation of Intestinal Tumors

Guihua Wang, Tongji Hospital, China
Short Talk: A Peptide Inhibitor Targeting p55PIK PI 3-Kinase Regulatory Subunit is Effective in Cancer Therapy

XiangMei Chen, Peking University, China
Short Talk: Aberrant Hypermethylation of Retinoic Acid Signaling Related Genes RARâ1/CRBP1/TIG1 in Gastric Carcinoma

09:45—10:15
Coffee Break

Jinyun Foyer
17:00—17:30
Coffee Available

Jinyun Foyer
17:30—19:30
New Horizon in Early Detection and Therapies II
Meeting has ended...abstracts no longer viewable online.

Jinyun Ballroom
* Yang Ke, Peking University, China

Snorri S. Thorgeirsson, National Institutes of Health, USA
Genomic Decoding of Human Liver Cancer

Peter R. Galle, University of Mainz, Germany
Signal Transduction Pathways and Targeted Therapies in HCC

19:30—20:30
Social Hour with Lite Bites

Jinyun Foyer

FRIDAY, OCTOBER 19

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge additional support for this conference from:

AstraZeneca

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


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If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

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If you are interested in becoming an advertising/marketing in-kind partner, please contact:
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Phone:+1 970-262-2676