Copper Mountain Resort Floorplan

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This meeting took place in 2008



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Pathological and Physiological Regulation of Cardiac Hypertrophy (A4)


Organizer(s) Leslie A. Leinwand and Eric N. Olson
January 13—18, 2008
Copper Mountain Resort • Copper Mountain, Colorado USA
Abstract Deadline: Sep 14, 2007
Late Abstract Deadline: Oct 17, 2007
Scholarship Deadline: Sep 14, 2007
Early Registration Deadline: Nov 13, 2007

Sponsored by Novartis Institutes for BioMedical Research

Summary of Meeting:
Heart disease remains a leading cause of death and constitutes a complex array of disorders. This meeting will explore new areas of research on how the heart adapts to a wide variety of stimuli including exercise, diet, and genetic background. In the post-genome era, it is now possible to contemplate new heart disease therapies such as through tissue engineering, and stem cell and molecular therapies. The role of microRNAs in regulating cardiac development and disease is an exciting new field of study. We will also consider understanding the mechanisms that animals in nature use to regulate their hearts during hibernation and fasting and feeding.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, JANUARY 13

15:00—19:30
Registration

Kokopelli's
18:30—19:30
Refreshments

Kokopelli's
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Bighorn A
James A. Spudich, Stanford University, USA
How do Myosins Really Work?


MONDAY, JANUARY 14

07:00—08:00
Breakfast

Kokopelli's
08:00—11:00
MicroRNAs in Cardiac Development and Disease
Meeting has ended...abstracts no longer viewable online.

Bighorn A
* Eric N. Olson, University of Texas Southwestern Medical Center, USA

Deepak Srivastava, Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
MicroRNA Regulation of Cardiac Cell Fate, Morphogenesis and Maintenance

Eva van Rooij, Hubrecht Institute, Netherlands
Stress Responsive microRNAs and their Control of Cardiac Disease

Michel A.J. Georges, University of Liège, Belgium
Uncovering Roles for miRNAs in Shaping Phenotypic Variability in Domestic Animals

Minoru Omi, Tohoku University, Japan
Short Talk: miR-21 is Required for Heart Valve Formation in Zebrafish

Prakash K. Rao, Novartis Institute for Biomedical Research, USA
Short Talk: The Role of MicroRNAs in Muscle Maintenance

09:20—09:40
Coffee Break

Kokopelli's
11:00—13:00
Poster Setup

Big Horn C
13:00—22:00
Poster Viewing

Big Horn C
16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Cardiac Remodeling
Meeting has ended...abstracts no longer viewable online.

Bighorn A
* Robert J. Schwartz, Texas A&M University, USA
Serum Response Factor

Eric N. Olson, University of Texas Southwestern Medical Center, USA
The Myomir Network

Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
Unexpected Role for T-type Calcium entry in regulating Cardiac Growth

Michael D. Schneider, Imperial College London, UK
Cardiac Specification in Embryonic Stem CellsCardiac Specification in Embryonic Stem Cells

19:00—20:00
Social Hour with Lite Bites

Kokopelli's
19:30—22:00
Poster Session 1

Big Horn C

TUESDAY, JANUARY 15

07:00—08:00
Breakfast

Kokopelli's
08:00—11:00
Hibernating and Feeding: What We Can Learn from Nature about Maintenance of Cardiac and Skeletal Muscle Mass
Meeting has ended...abstracts no longer viewable online.

Bighorn A
* Nadia A. Rosenthal, The Jackson Laboratory, USA

Stephen M. Secor, University of Alabama, USA
The Python Heart: Extreme Regulation of Form and Function

Thomas G. Marr, Hiberna Corporation, USA
Profound Mammalian Hibernation

Nadia A. Rosenthal, The Jackson Laboratory, USA
The Role of IGF1 in Maintaining Muscle Mass in Heart Failure

09:20—09:40
Coffee Break

Kokopelli's
11:00—13:00
Poster Setup

Big Horn C
13:00—22:00
Poster Viewing

Big Horn C
16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
The Effects of Heart Disease on Skeletal Muscle
Meeting has ended...abstracts no longer viewable online.

Bighorn A
* Elizabeth M. McNally, Northwestern University, USA

* Elizabeth M. McNally, Northwestern University, USA

Daniel P. Kelly, University of Pennsylvania, USA
PGC-1 Coactivators in Heart and Skeletal Muscle

Andrew R. Marks, Columbia University College of Physicians and Surgeons, USA
Remodeling of the RyR1 Channel Complex Causes Impaired Exercise Capacity in Heart Failure

Steven R. Houser, Temple University School of Medicine, USA
Differing Viewpoints on RyR and Heart Failure

19:00—20:00
Social Hour with Lite Bites

Kokopelli's
19:30—22:00
Poster Session 2

Big Horn C

WEDNESDAY, JANUARY 16

07:00—08:00
Breakfast

Kokopelli's
08:00—11:00
Modifiers of Heart Disease
Meeting has ended...abstracts no longer viewable online.

Bighorn A
Leslie A. Leinwand, University of Colorado Boulder, USA
A Tale of Two Diets: Diet Affects the Heart

* Christine E. Seidman, Harvard Medical School, USA
Mechanistic Insight through Deep Transcriptional Profiling

Joseph H. Nadeau, Pacific Northwest Research Institute, USA
Genetic Architecture of Complex Traits in Chromosome Substitution Strains

Da-Zhi Wang, Children's Hospital Boston, USA
miRNAs that Regulate Cardiac Development and Function

09:20—09:40
Coffee Break

Kokopelli's
11:00—13:00
Poster Setup

Big Horn C
13:00—22:00
Poster Viewing

Big Horn C
16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Is Blocking Pathologic Hypertrophy a Good Therapeutic Strategy?
Meeting has ended...abstracts no longer viewable online.

Bighorn A
* Michael R. Bristow, University of Colorado Anschutz Medical Campus, USA
Maladaptive Remodeling of the Human Left Ventricle as a Therapeutic Target

Jeffrey Robbins, Cincinnati Children's Hospital Medical Center, USA
Pathologic Hypertrophy – an Unfolding Story

Fady Malik, Cytokinetics Inc., USA
Can Small Molecules Improve Cardiac Performance?

Joseph A. Hill, University of Texas Southwestern Medical Center, USA
Short Talk: Cardiomyocyte Autophagy in the Pathogenesis of Heart Failure

19:00—20:00
Social Hour with Lite Bites

Kokopelli's
19:30—22:00
Poster Session 3

Big Horn C

THURSDAY, JANUARY 17

07:00—08:00
Breakfast

Kokopelli's
08:00—11:00
Stem Cells and Gene Therapy: The Ongoing Debate
Meeting has ended...abstracts no longer viewable online.

Bighorn A
* Daniel P. Kelly, University of Pennsylvania, USA

Yuh-Shin Chang, Massachusetts General Hospital, USA
A Stretch-Activated Survival Pathway in Heart Progenitors and Their Progeny Mediates by the ER/SR Transcription Factor Creb3L2

Elizabeth M. McNally, Northwestern University, USA
Regeneration and Repair in Skeletal Muscle

Elizabeth M. McNally, Northwestern University, USA
Regeneration and Repair in Skeletal Muscle

Ulrich Martin, Hannover Medical School, Germany
Short Talk: Cardiac Differentiation of Induced Pluripotent Stem (iPS) Cells

Jay W. Schneider, University of Texas Southwestern Medical Center, USA
Short Talk: Small Molecules that Promote Fate and Myocardial Repair

09:20—09:40
Coffee Break

Kokopelli's
16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Tissue Engineering of Valves and Hearts
Meeting has ended...abstracts no longer viewable online.

Bighorn A
* Leslie A. Leinwand, University of Colorado Boulder, USA

Kristi S. Anseth, HHMI/University of Colorado, USA
Hydrogel Niches for 3D Culture of Valvular Interstitial Cells: Approaches to Valve Regeneration

Thomas Eschenhagen, University Medical Center Hamburg-Eppendorf, Germany
A Functional Construct of Myocardium for Drug Screening and Target Validation

Doris A. Taylor, Texas Heart Institute, USA
Cells for Cure of CVD: Science or Science Fiction?

19:00—20:00
Social Hour with Lite Bites

Kokopelli's
20:00—23:00
Entertainment

Bighorn C

FRIDAY, JANUARY 18

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HL091551-01




We gratefully acknowledge additional support for this conference from:


American Heart Association's Council on Basic Cardiovascular Sciences

Boehringer Ingelheim Pharmaceuticals, Inc.
Novartis Institutes for BioMedical Research
 

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Cytokinetics, Inc.


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