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This meeting took place in 2008



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Molecular Mechanisms of Angiogenesis in Development and Disease (J5)


Organizer(s) Mark W. Majesky, Peter M. Carmeliet and Luisa Iruela-Arispe
January 15—20, 2008
Fairmont Hotel Vancouver • Vancouver, British Columbia Canada
Abstract Deadline: Sep 17, 2007
Late Abstract Deadline: Oct 22, 2007
Scholarship Deadline: Sep 17, 2007
Early Registration Deadline: Nov 19, 2007

Sponsored by Abbott Laboratories and Genentech, Inc.


Summary of Meeting:
This conference will discuss advances in vascular biology and angiogenesis research, with an emphasis on the role of developmental pathways in vascular disease. Substantial progress has been made in our understanding of molecular mechanisms that direct early steps in vascular development. Yet many important questions remain in the areas of angioblast formation, establishment of arterial, venous and lymphatic identity, lumen formation and stabilization of nascent vessels by mural cell recruitment. Moreover, lineage-mapping studies show that blood vessels are highly mosaic in their origins, raising new questions about the role of lineage diversity in patterns of vascular disease seen in adult vessels. Intrinsic pathways for planar cell polarity in endothelial cells will be discussed in terms of vascular growth, responses to blood flow, repair of endothelial injury, and tube formation. Lessons learned from genetic studies in model organisms will be applied to questions concerning how angiogenesis is controlled by soluble growth factors, cell-matrix interactions, proteases, hypoxia and heterotypic cell-cell interactions in higher vertebrates. An important and highly-debated topic in the field involves the multiple types of endothelial progenitor cells that have been identified, and what promise they may hold for vascular therapeutic applications. An update on these questions will be included, along with discussions of advances in vascular imaging, and emerging novel angiogenesis and anti-angiogenesis strategies. Thus, an integrated view of angiogenesis linking developmental pathways and disease pathogenesis will be presented so as to highlight basic mechanisms and identify new opportunities for control of blood vessel formation in tissue ischemia, wound repair, diabetes and cancer.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, JANUARY 15

15:00—19:30
Registration

BC Foyer
18:30—19:30
Refreshments

BC Foyer
19:30—21:30
Keynote Session (Joint)
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
Salvador Moncada, University of Manchester, UK
Nitric Oxide and Oxygen Homeostasis


WEDNESDAY, JANUARY 16

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:00
Vascular Development
Meeting has ended...abstracts no longer viewable online.

British Ballroom
* Peter F. Carmeliet, University of Leuven, VIB, Belgium

Brant M. Weinstein, NICHD, National Institutes of Health, USA
Pathways for Arterial Specification in Zebrafish

Takashi Mikawa, Cardiovascular Research Institute, University of California, San Francisco, USA
Control of Vessel Patterning by BMP Signaling

Sophia Y. Tsai, Baylor College of Medicine, USA
Role of COUP-TFII in Venous Specification

Michael Simons, Yale University, USA
Regulation of Arterial Branching Morphogenesis

Robert Herpers, Hubrecht Institute, Netherlands
Short Talk: Redundant Roles for sox7 and sox18 in Arteriovenous Specification in Zebrafish

08:00—11:00
Oxygen and Cells
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Lorenz Poellinger, Karolinska Institutet, Sweden

Sten Lindahl, Karolinska Institutet, Sweden
Short Talk: Oxygen Biology: An Historical Perspective

Peter J. Ratcliffe, University of Oxford, UK
Protein Hydroxylation and the Cellular Response to Hypoxia

Paul T. Schumacker, Northwestern University, USA
Signaling by Mitochondrial Reactive Oxygen Species during Hypoxia

Edward T.H. Yeh, University of Texas MD Anderson Cancer Center, USA
Short Talk: SUMO-specific Protease 1 is Essential for Stabilization of HIF-1alpha during Hypoxia

Bradly G. Wouters, University Health Network, Canada
Short Talk: Hypoxia Inhibits Disulfide Bond Formation and Protein Folding in the Endoplasmic Reticulum

Walter F. Boron, Case Western Reserve University, USA
Gas Channels

José López-Barneo, Hospital Universitario Virgen del Rocío, Spain
Facilitated O2 Diffusion and O2 Regulated Ion Channels

09:20—09:40
Coffee Break

BC Foyer
11:00—13:00
Poster Setup

Pacific Ballroom
13:00—22:00
Poster Viewing

Pacific Ballroom
14:30—16:30
Workshop 1: Experimental Models of Angiogenesis

British Ballroom
* George E. Davis, University of Missouri School of Medicine, USA

Jeffrey J. Essner, Iowa State University, USA
Moesin is Required For VEGF-dependent Endothelial Tube Formation In Vivo

Maria J. Machado, INSERM U833, France
Longitudinal Analyses of Blind-Ended Vessel Permeability During Angiogenesis in vivo

Jing Chen, Boston Children's Hospital / Harvard Medical School, USA
Erythropoietin Prevents Pathologic Vessel Loss and Subsequent Proliferation in a Mouse Model of Oxygen-Induced Retinopathy

Theresa T. Lu, Hospital for Special Surgery/Weill Cornell Medicine, USA
Dendritic Cells Regulate Lymph Node Vascular Growth

Bruno Larrivée, College de France, France
Activation of the UNC5B Receptor by Netrin-1 Inhibits Sprouting Angiogenesis

Ping Ao, University of Washington, USA
Cancer Genesis and Progression as Dynamics in Functional Landscape of Endogenous Molecular-Cellular Network

14:30—16:30
Workshop 1: Neurophysiological Responses to Hypoxia

Columbia Ballroom
* Jan-Marino Ramirez, University of Chicago, USA

Ganesh K. Kumar, University Of Chicago, USA
ROS Signaling Mediates Intermittent Hypoxia-Induced Neurotransmitter Synthesis Via Post-translational Modifications of Synthesizing Enzymes

Stephen T. Brown, McMaster University, Canada
Chronic Hypoxia Regulates Genes Important for Metabolism, Packaging, and Secretion of Catecholamines in an Immortalized Adrenomedullary Chromaffin Cell Line

Alfredo J. Garcia, University of Chicago, USA
Redox State Modulates the Respiratory Rhythmogenesis in the Pre-Botzinger Complex

Jay B. Dean, University of South Florida, USA
Hyperoxia Induces CA1 Hippocampal Redox Stress, Neural Plasticity, and Hyperexcitability in Rat Brain Slices

Thomas F. Floyd, Stony Brook University, USA
Impact of Aging Upon Cerebral Hypoxia Sensing of Anemia

Fei Meng†, Birmingham University, UK
Hypoxia-induced Calcium Elevation in Human Embryonic Kidney Cells

16:30—17:00
Coffee Available

BC Foyer
17:00—19:00
Endothelial Guidance and Signaling
Meeting has ended...abstracts no longer viewable online.

British Ballroom
* Luisa Iruela-Arispe, University of California, Los Angeles, USA

Tuomas Tammela, Koch Institute for Integrative Cancer Research at MIT, USA
Featured Speaker: "Next Generation of Vascular Biologists": VEGF-C/VEGFR-3 in Angiogenic Sprouting and Lymphatic Vessel Maturation

Holger Gerhardt, Max Delbrück Center for Molecular Medicine, Germany
Molecular Regulation of Endothelial Tip and Stalk Cells in Sprouting Angiogenesis

Christiana Ruhrberg, University College London, UK
Neuropilin Signalling in Neuronal and Vascular Development

Michael Potente, Max Planck Institute for Heart and Lung Research, Germany
Short Talk: SIRT1 Regulates Endothelial Tip Cell Formation during Sprouting Angiogenesis

Michael Potente, Max Planck Institute for Heart and Lung Research, Germany
Short Talk: SIRT1 Regulates Endothelial Tip Cell Formation during Sprouting Angiogenesis

17:00—19:00
Adaptive Responses to Hypoxia
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Randall S. Johnson, University of Cambridge, UK

Gregg L. Semenza, Johns Hopkins University School of Medicine, USA
Role of Hypoxia-Inducible Factor 1 in Oxygen Homeostasis

Joseph A. Garcia, University of Texas Southwestern Medical Center, USA
Molecular Mechanisms Underlying HIF-2 Selective Signal Transduction

John G. Wood, University of Kansas Medical Center, USA
Short Talk: Microvascular Acclimatization to Hypoxia

Mircea Ivan, Tufts-New England Medical Center, USA
Short Talk: A microRNA Component of the Hypoxia Response

Cynthia M. Beall, Case Western Reserve University, USA
Contrasting Adaptations to Hypoxia by Andean, Tibetan and East African Populations

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
19:30—22:00
Poster Session 1

Pacific Ballroom

THURSDAY, JANUARY 17

07:00—08:00
Breakfast

Pacific Ballroom
07:00—08:00
Poster Setup

Pacific Ballroom
08:00—11:00
Angiogenesis in Disease & Tissue Maintenance
Meeting has ended...abstracts no longer viewable online.

British Ballroom
* Michael Simons, Yale University, USA

Peter F. Carmeliet, University of Leuven, VIB, Belgium
Hypoxia, Angiogenesis, Metabolism

Gavin O. Thurston, Regeneron Pharmaceuticals Inc., USA
Dll4-Notch Signaling in Angiogenesis

Florian P. Limbourg, Medizinische Hochschule Hannover, Germany
Short Talk: Notch Signaling in the Arterial Endothelium Determines Postnatal Arteriogenesis

Donald M. McDonald, University of California, San Francisco, USA
Endothelial-Pericyte Interactions in Angiogenic Blood Vessels

Charles A. Lambert, Tour de Pathologie B23/3, Belgium
Short Talk: VEGF111, a New VEGF-A Isoform Induced by Genotoxic Agents: Resistance to Proteolytic Degradation and Effect on Heart Ischemia after Infarction in Mice

Jason U. Tilan, Georgetown University, USA
Short Talk: The NPY-Y2 Receptor (R) System and Platelets are Important for Ischemic Angiogenesis.

08:00—11:00
Development and Differentiation
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Peter J. Ratcliffe, University of Oxford, UK

Randall S. Johnson, University of Cambridge, UK
Tissue-Specific Effects of HIF-1 Loss of Function

Guo-Hua Fong, University of Connecticut Health Center, USA
Short Talk: The HIF-Specific Prolyl Hydroxylase PHD2 Protein may be Directly Required in the Vascular Endothelium to Prevent Excessive Angiogenesis in Mice

Erinn B. Rankin, Stanford University, USA
Short Talk: Hypoxia-Inducible Factor 2 Regulates VHL Associated Vascular Tumorigenesis and Hepatic Lipid Metabolism In Vivo

Susan Quaggin, Northwestern University, USA
Podocyte-Endothelial Interactions and Angiogenic Factors in the Kidney

Ellen van Rooijen, Hubrecht Institute, Developmental Biology and Stem Cell Research, Netherlands
Short Talk: The von Hippel-Lindau Tumor Suppressor Gene Ortholog vhl1 Regulates Zebrafish Hematopoiesis

Lorenz Poellinger, Karolinska Institutet, Sweden
Oxygen-Dependent Regulation of Cellular Differentiation

M. Celeste Simon, University of Pennsylvania, USA
Hypoxia and Stem Cells

09:20—09:40
Coffee Break

BC Foyer
11:30—12:30
Lunch

Pacific Ballroom
12:00—14:30
Poster Session 2

Pacific Ballroom
14:30—16:30
Workshop 2: Stem Cells and Endothelial Progenitors

British Ballroom
* Karen K. Hirschi, Yale University, USA

Jessica L. Dries, East Carolina University, USA
Enhanced Post-MI Angiogenesis Protects Hearts of Mice Null for the Circadian Clock Gene mPer2

Tatiana V. Byzova, Cleveland Clinic Foundation, USA
Beta 3 Integrin Function on Bone Marrow-Derived Cells Determines the Course of Adaptive and Pathological Angiogenesis

Masamichi Eguchi, Tukai University School of Medicine, Japan
Thrombopoietin (TPO) Contributes to Therapeutic Vasculogenesis through Promoting Mobilization and Survival of Endothelial Progenitor Cells (EPCs) via akt/mTOR/p70S6K Pathway

Elazar Zelzer, Weizmann Institute of Science, Israel
SOX9 Regulation of Vegf in the Developing Skeleton Regulates Early Limb Vasculature Patterning

Priya Prahalad, Georgetown University, USA
9-cis-Retinoic Acid Mediated Regulation of Vasculogenic Mimicry in Breast Cancer

14:30—16:30
Workshop 2: Animal Models

Columbia Ballroom
* M. Celeste Simon, University of Pennsylvania, USA

Xin Qi, Stanford University School of Medicine, USA
The Complex of Protein Kinase C delta and c-Abl Communicates Endoplasmic Reticulum Stress to the Mitochondria; an Essential Step in the Subsequent Apoptosis

Reiko Inagi, University of Tokyo School of Medicine, Japan
Glyoxalase I Overexpression Lowers Oxidative Stress and Ameliorates Renal Ischemia-Reperfusion Injury in the Rat

Sunghee Cho, Cornell University, Burke Medical Research Institute, USA
Hyperlipidemia Exacerbates Ischemic Brain Injury Via CD36-mediated Foam Cell Formation

Gail Walkinshaw, Fibrogen, USA
Novel HIF Prolyl Hydroxylase Inhibitors are Neuroprotective in Both Permanent and Transient Rodent Models of Middle Cerebral Artery Occlusion

Holger K. Eltzschig, University of Colorado Denver, USA
Role of HIF-1alpha in A2B Adenosine Receptor-dependent Cardioprotection During Ischemic Preconditioning

Mikko A. I. Keränen, University of Helsinki,, Finland
Constitutively Expressed Hypoxia-Inducible Factor-1Ą Prevents the Development of Cardiac Allograft Vasculopathy in the Rat

Cormac Taylor, University College Dublin, Ireland
The Hydroxylase Inhibitor DMOG is Protective in a Murine Model of Colitis

16:30—17:00
Coffee Available

BC Foyer
17:00—19:00
Extracellular Matrix and Angiogenesis
Meeting has ended...abstracts no longer viewable online.

British Ballroom
* Victoria L. Bautch, University of North Carolina at Chapel Hill, USA

Weilan Ye, Genentech, Inc., USA
The Roles of EGFL7 and EGFL8 in Vascular Morphogenesis

David A. Cheresh, University of California, San Diego, USA
Chemical Disruption of B-RAF/C-RAF Dimerization Blocks Angiogenesis and Tumor Growth

R. Andrea DeYoung, University of California, Los Angeles, USA
Short Talk: An Essential Role for CCN2 in Skin Angiogenesis

17:00—19:00
Metabolism
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Chi Van Dang, University of Pennsylvania, USA
Oxygen-Dependent Regulation of Glucose Metabolism and Oncogenesis: Interplay between MYC and HIF

Kathleen A. O'Hagan, University College Dublin, Ireland
Short Talk: PGC-1alpha Induced Increase in Oxygen Consumption Leads to Activity of HIF Target Genes

Julián Aragonés Lopez, Research Institute Princesa, Spain
Short Talk: PHD1 Deficient Mice Lower Oxygen Consumption by Reprogramming Skeletal Muscle Glucose Metabolism via PPARA Transcription Factor

Robert T. Abraham, Pfizer Worldwide Research and Development, USA
Interplay between mTOR Signaling and Autophagy during Metabolic Stress in Human Cancer Cells

Keith Laderoute, SRI International, USA
5'-AMP-Activated Protein Kinase (AMPK): Overview and Relevance for Tumor Biology

19:00
On Own for Dinner


FRIDAY, JANUARY 18

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:00
Endothelial Progenitors, Ischemia and Cardiovascular Disease (Joint)
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Mark W. Majesky, University of North Carolina at Chapel Hill, USA

* Gregg L. Semenza, Johns Hopkins University School of Medicine, USA

Eli Keshet, Hebrew University, Israel
Angiogenic- and non-Angiogenic Roles of VEGF in Adult Organs

Maria B. Grant, University of Florida, USA
IGF Binding Protein-3 Regulates Hematopoietic Stem Cell and Endothelial Precursor Cell Function During Vascular Development

Vivek Mittal, Weill Cornell Medical College, USA
Bone Marrow-Derived Endothelial Progenitor Cells Regulate the Angiogenic Switch in Tumor Growth and Metastasis

Stefanie Dimmeler, University of Frankfurt, Germany
Bone Marrow Progenitor Cell Therapy for Myocardial Infarction

09:20—09:40
Coffee Break

BC Foyer
11:00—13:00
Poster Setup

Pacific Ballroom
13:00—22:00
Poster Viewing

Pacific Ballroom
16:30—17:00
Coffee Available

BC Foyer
17:00—19:00
Vascular Growth, Assembly, and Polarity
Meeting has ended...abstracts no longer viewable online.

British Ballroom
* Eli Keshet, Hebrew University, Israel

Mark A. Krasnow, Stanford University School of Medicine, USA
Genetic Dissection of Tube Formation and Branching

George E. Davis, University of Missouri School of Medicine, USA
Molecular Control of Endothelial Lumen Formation

Victoria L. Bautch, University of North Carolina at Chapel Hill, USA
Integrating Cell Division and Vascular Morphogenesis

Hiroyasu Kidoya, Research Institute for Microbial Diseases, Osaka University, Japan
Short Talk: Apelin, as an Induction Factor for Neovascular Maturation

17:00—19:00
ROS and Redox
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Nanduri R. Prabhakar, University of Chicago, USA
Responses to Intermittent Hypoxia: Consequences of Altered Red-Ox Homeostasis?

Stephen L. Archer, Queen's University, Canada
Metabolic-Electric Signaling in the Pulmonary Circulation - The Interface Between Oxygen Sensing, Pulmonary Hypertension and Cancer

Kay F. Macleod, University of Chicago, USA
Short Talk: Regulation of Mitochondrial Integrity, Autophagy, and Cell Survival by BNIP3

Patrick van Uden, Dundee University, Scotland
Short Talk: NF-kappaB modulates the HIF pathway

Masayuki Yamamoto, Tohoku University Graduate School of Medicine, Japan
Protective Responses to Oxidant Stress

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
19:30—22:00
Poster Session 3

Pacific Ballroom

SATURDAY, JANUARY 19

07:00—08:00
Breakfast

Pacific Ballroom
07:00—08:00
Poster Setup

Pacific Ballroom
08:00—11:00
Pathological Angiogenesis
Meeting has ended...abstracts no longer viewable online.

British Ballroom
* Arie Horowitz, Thomas Jefferson University, USA

Michael J. Detmar, ETH - Zürich, Switzerland
Tumor Lymphangiogenesis

Christiana DelloRusso, Children's Hospital Boston, USA
Short Talk: Loss of p53 Tumor Suppressor Function may be Rescued by Re-Expression of the Endogenous Angiogenesis Inhibitors TSP-1 and Endostatin

Shira Landskroner, Alexion Pharmaceuticals, USA
Short Talk: The Adipocyte-Derived Factor Adiponectin Contributes to Mammary Tumor Growth through Enhanced Angiogenesis

Gabriele A.I. Bergers, University of California, San Francisco, USA
Regulation and Function of Bone Marrow-Derived Cells in Tumors

Daniela C. Tirziu, Yale University School of Medicine, USA
Short Talk: Angiogenesis-Driven Myocardial Hypertrophy

Yoshihide Asano, Medical University of South Carolina, USA
Short Talk: Fli1 Impairs the Interaction of Endothelial Cells with Pericytes - a Possible Mechanism for Scleroderma Vasculopathy

Christopher G. Kevil, Louisiana State University Health Sciences Center, USA
Short Talk: Endothelial Cav-1 Mediates Pathological Angiogenesis in the 3% DSS Model of Experimental Colitis

08:00—11:00
Cancer
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
William G. Kaelin, Jr., Dana-Farber Cancer Institute, USA
The VHL Gene: Oxygen Sensing and Cancer

Poul H. B. Sorensen, University of British Columbia, Canada
Short Talk: A Novel E3 Ubiquitin Ligase HACE1 Represses HIF-1alpha Accumulation Under Hypoxic Conditions

Jacques Pouysségur, University of Nice, France
Targeting Hypoxia-Induced Tumor Metabolism

Amato J. Giaccia, Stanford University, USA
Hypoxia Induced Gene Expression in Cancer Cells

Erwin G. Van Meir, Emory University School of Medicine, USA
Short Talk: KCN1, a Novel HIF Inhibitor Blocks Tumor Growth Through Binding of Plectin-1 and Inhibition of the HSP90 Pathway

* Mark W. Dewhirst, Duke University Medical Center, USA
Exploring Oxidative Stress and HIF-1 in Early Angiogenesis and Response to Radiotherapy and Chemotherapy

Annamaria Rapisarda, SAIC-Frederick, Inc., USA
Short Talk: Antitumor Activity of Antiangiogenic Agents Combined with HIF-1 Inhibitors: Blocking Hypoxic Dependent Survival Pathways Improves Therapeutic Efficacy

09:20—09:40
Coffee Break

BC Foyer
11:30—12:30
Lunch

Pacific Ballroom
12:00—14:30
Poster Session 4

Pacific Ballroom
14:30—16:30
Workshop 3: Therapeutics

Columbia Ballroom
* Amato J. Giaccia, Stanford University, USA

Joseph R. Marszalek, Merck Research Laboratories, USA
Using RNAi to Identify Modulators of the HIF Pathway/Hypoxia for Cancer

Navdeep S. Chandel, Northwestern University, USA
A Chemical Genomics Screen Highlights the Essential Role of Mitochondria in HIF Regulation

Natalya A. Smirnova, Burke Research Medical Institute, USA
High-throughput Screening for HIF Prolyl Hydroxylase Inhibitors

Stephen John Klaus, Fibrogen, USA
Induction of Erythropoiesis in Rodents by Novel and Distinct Families of Orally Active HIF Prolyl Hydroxylase Inhibitors

Sean P. Colgan, University of Colorado Denver, USA
Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

Shan Ping Yu, Emory University School of Medicine, USA
In Vitro Hypoxic Preconditioning of Stem Cells as a Strategy of Promoting Cell Survival and Functional Benefits After Transplantation into the Ischemic Rat Brain

Periannan Kuppusamy†, Ohio State University, USA
Oxygen Sensing in Myocardial Stem Cell Therapy

14:30—16:30
Workshop 3: Vascular Cell Signaling

British Ballroom
* Donald M. McDonald, University of California, San Francisco, USA

Suphansa Sawamiphak, Max Planck Institute of Neurobiology, Germany
Eph/Ephrin-Mediated Endothelial Cell Interactions

Masahiro Murakami, Yale University School of Medicine, USA
Mechanism of FGF-Mediated Maintenance of Vascular Integrity

Tetsuya Saito, University of Tokyo, Japan
Molecular Mechanism of Alternative VEGFR-1 Gene Expression in Human Endothelial Cell

Richard J. Bodnar, University of Pittsburgh, USA
Vessel Dissociation: The Role of CXC Receptor 3

Arie Horowitz, Thomas Jefferson University, USA
VEGF and Semaphorin Induce Neuropilin-1 Endocytosis via Separate Pathways

Robert C. Doebele, University of Colorado, USA
Epac/Rap1 Inhibit Endothelial Cell Chemotaxis and Angiogenesis via Induction of Thrombospondin-1

16:30—17:00
Coffee Available

BC Foyer
17:00—19:00
Novel Therapeutic Targets in Angiogenesis
Meeting has ended...abstracts no longer viewable online.

British Ballroom
* Gabriele A.I. Bergers, University of California, San Francisco, USA

Paul R. Riley, University of Oxford, UK
Thymosin beta4 and Coronary Angiogenesis

Zoltan P. Arany, University of Pennsylvania, USA
Short Talk: HIF-Independent Regulation of VEGF and Angiogenesis by the Metabolic Sensor and Transcriptional Coactivator PGC-1á

Sara Weis, University of California, San Diego, USA
Short Talk: Compensatory Role for Pyk2 during Angiogenesis in Adult Mice Lacking Endothelial Cell FAK

Angela K. Nevins, Indiana University School of Medicine, USA
Short Talk: The Role of VEGF-Induced Surface Expression of Nucleolin in Tumor Angiogenesis

Melanie A. Simpson, University of Nebraska, USA
Short Talk: Prostate Tumor Growth, Vascularization, and Metastasis are Modulated by Differential Turnover of Hyaluronan

Kristin E. Hubert, Oregon Health & Sciences University, USA
Short Talk: Trail Deficient Mice Exhibit Delayed Regression of Retinal Neovascularization

17:00—19:00
Respiratory Disease
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Peter A. Robbins, University of Oxford, UK
Hypoxia and Mechanisms of Cardio-Respiratory Control in Humans

Larrisa A. Shimoda, Johns Hopkins School of Medicine, USA
Hypoxic Pulmonary Hypertension

Michael L. Maitland, University of Chicago, USA
Short Talk: Developing the Anti-cancer VEGFR2/Multikinase Inhibitor Sorafenib for Treatment of Human Pulmonary Arterial Hypertension

Agnes Görlach, German Heart Center Munich, Germany
Short Talk: The Serum- and Glucocorticoid Regulated Kinase-1 is a Novel Regulator of Hypoxia-Inducible Factor 1

Michail Sitkovsky, Northeastern University, USA
Iatrogenic Complication Due to Elimination of Hypoxia-driven, Immunosuppressive and Tissue Protecting Adenosinergic Pathway

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
20:00—23:00
Entertainment

Pacific Ballroom

SUNDAY, JANUARY 20

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge additional support for this conference from:

Abbott Laboratories Genentech, Inc.
March of Dimes Foundation
 

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


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