Fairmont Banff Springs Floorplan

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This meeting took place in 2008



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HIV Pathogenesis (X8)


Organizer(s) Steven M. Wolinsky, John P. Moore and Bette T. Korber
March 27—April 1, 2008
Fairmont Banff Springs • Banff, Alberta Canada
Abstract Deadline: Nov 28, 2007
Late Abstract Deadline: Dec 28, 2007
Scholarship Deadline: Nov 28, 2007
Early Registration Deadline: Jan 28, 2008

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation


Summary of Meeting:
Elucidating the molecular mechanisms of HIV infection is essential for the design and development of an effective vaccine and the next generation of antiviral agents. This Keystone Symposia meeting will focus on (1) our understanding of HIV proteins and their functions, (2) host factors used to aid in viral replication, (3) viral genetic diversity and adaptation, and (4) the central role of the destruction of CD4+ T cells in lymphoid tissue to the pathogenesis. The pathogenic mechanisms of HIV infection from transmission through clinical latency, including the means used by the virus to establish infection and propagate in target cells and evade the innate and adaptive host defense mechanisms will be examined. Scientists from diverse disciplines will be brought together with the objective of devising vaccines and other biology-based ways to prevent transmission and progression to AIDS. The meeting will promote further insights into the dynamic interplay between the virus, the host, and its immune response.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


THURSDAY, MARCH 27

15:00—19:30
Registration

Van Horne Ballroom Foyer
18:30—19:30
Refreshments

Van Horne Ballroom Foyer
19:30—21:30
Keynote Session (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom
* Steven Wolinsky, Northwestern University, USA

Henry A. Erlich, Roche Molecular Systems, USA
HLA Allelic and Haplotypic Diversity and Host Immunity

Dan H. Barouch, Harvard Medical School/Beth Israel Deaconess Medical Center, USA

Lawrence Corey, Fred Hutchinson Cancer Research Center, USA
HIV Vaccines: The Way Forward


FRIDAY, MARCH 28

07:00—08:00
Breakfast

New Brunswick, Alberta, Cascade
08:00—11:00
Biology of Transmission (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom
* Steven Wolinsky, Northwestern University, USA

Ashley T. Haase, University of Minnesota, USA
Sexual Mucosal Transmission

Daniel C. Douek, NIAID, National Institutes of Health, USA
Immune Events in the HIV-Infected Gut

Thomas J. Hope, Northwestern University, Feinberg School of Medicine, USA
Analysis of the Early Interactions of HIV with Human Cervical Explants and the Rhesus Macaque Female Genital Tract: The First 4 Hours of Virus Exposure

James Arthos, NIAID, National Institutes of Health, USA
Short Talk: HIV-1 Envelope Binds to and Signals through alpha4beta7 Integrin, the Gut Mucosal Homing Receptor for Peripheral T Cells

Frank Wegmann, Janssen, Netherlands
Short Talk: Combining HIV Antigens and Polyanionic Microbicides to Induce High Levels of Mucosal Env-Specific Antibodies

09:20—09:40
Coffee Break

Van Horne Ballroom Foyer
11:00—13:00
Poster Setup

New Brunswick, Alberta, Cascade
13:00—22:00
Poster Viewing

New Brunswick, Alberta, Cascade
12:00—13:30
Hands-on Computer Session on Los Alamos Sequence Database
Maximum attendance: 60. Interested participants may sign up at the meeting on a first-come, first-serve basis.

Beatty/Coleman
Thomas K. Leitner, Los Alamos National Laboratory, USA

Bette Tina Marie Korber, Los Alamos National Laboratory, USA

14:30—16:30
Workshop 1: Pathogenic and Non-Pathogenic Pathways

Van Horne Ballroom AB
* Cristian Apetrei, University of Pittsburgh, USA
Experimentally-Induced Immune Activation in Natural Hosts of SIVs Results in Significant Increases in Viral Replication

* Genoveffa Franchini, NCI, National Institutes of Health, USA
Preferential Loss of Th17 T Cells at Mucosal Sites and Immune Activation Predicts AIDS Progression

Mirko Paiardini, Emory University, YNPRC, USA
Th17 Cells in the Gut of Naturally SIV-Infected Sooty Mangabeys

Satya Dandekar, University of California, Davis, USA
Early Onset of Enteropathic Changes in SIV Infection Lead to Impaired IL-17 Orchestrated Gut Mucosal Immune Response Against Salmonella and cause its Systemic Dissemination from the Gut

Joern E. Schmitz, Beth Israel Deaconess Medical Center, USA
Adaptive Immune Responses Appear to Contribute Little to Viral Containment of SIVagm infection in African Green Monkeys

Thaidra A. Gaufin, Tulane National Primate Research Center, USA
Humoral Immune Responses have Little Impact on Controlling Viremia during SIVagm Infection of African Green Monkeys (AGMs)

Andre Durudas, Seattle Biomedical Research Institute, USA
Tissue Specific Inflammatory Responses are Associated with Disease Outcome Following Oral SIV Transmission

S. Rochelle Mikkelsen, North Carolina State University, USA
Transient Depletion of CD4+CD25+ Regulatory T Cells in Cats Chronically Infected with Feline Immunodeficiency Virus Improves Anti-Viral and Novel Immune Responses

14:30—16:30
Workshop 1 : Novel Vaccines and Adjuvants

Van Horne Ballroom C
* Rama Rao Amara, Emory University, USA

* Robert A. Seder, NIAID, National Institutes of Health, USA

Tomas Hanke, University of Oxford, UK
Development of a Universal T Cell Vaccine

Antu K. Dey, Novartis Vaccines & Diagnostics, USA
N-Terminal Substitutions in HIV-1 gp41 Reduce the Expression of non-Trimeric Envelope Glycoproteins on the Virus

Gerald Kimani Chege, University of Cape Town, South Africa
A Pantothenate Auxotrophic Strain of BCG Expressing HIV-1 Gag Induces Cellular Responses in Baboons, which are Efficiently Boosted by HIV-1 Pr55gag VLPs

Mario Roederer, NIAID, National Institutes of Health, USA
Fine Aerosol Adenovirus Vaccination against SIV and Tuberculosis in Rhesus Macaque

David B. Weiner, University of Pennsylvania School of Medicine, USA
Induction of Potent T Cell Immunity in Macaques by EP DNA + Molecular Adjuvants, Comparison of -Specific Responses Induced by Co-Vaccination of SIV DNA + Plasmid IL-12, IL-15 or RANTES in Rhesus Macaques

Sean X. Du†, Maxygen, USA
Directed Molecular Evolution Created Genetic and Antigenic Diversity and Improved Overall Immunogenicity of HIV-1 gp120 Immunogen

Mattias Forsell, Umeå University, Sweden
Elicitation of Co-Receptor Site Directed Antibodies against HIV-1 is caused by Primary Receptor Binding to the Viral Envelope Glycoproteins

16:30—17:00
Coffee Available

Van Horne Ballroom Foyer
17:00—19:15
Host and Viral Genetics
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
* Bette Tina Marie Korber, Los Alamos National Laboratory, USA

Sunil K. Ahuja, University of Texas Health Science Center, USA
Host Factors and Pathogenesis

Mary Carrington, Frederick National Laboratory for Cancer Research, USA
The Influence of HLA Class I and KIR on HIV-1 Disease

Beatrice H. Hahn, University of Pennsylvania, USA
HIV-1 Transmission and Early Viral Evolution

Christine M. Rousseau, University of Washington, USA
Short Talk: HLA-Driven Evolution of HIV-1 Subtype C: Immune Escape and Viral Fitness Costs

Athe M.N. Tsibris, Massachusetts General Hospital, USA
Short Talk: V3 Loop Sequence Dynamics in Subjects Failing CCR5 Antagonist Therapy

17:00—19:30
Progress in Clinical Trials of HIV Vaccines
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom C
* Peggy Johnston, NIAID, National Institutes of Health, USA

Susan P. Buchbinder, San Francisco Department of Public Health, USA
Primary Efficacy Results from the STEP Study (Merck V520 Protocol 023/HVTN 502)—a Phase II Test-of-Concept Trial of the MRKAd5 HIV-1 gag/pol/nef Trivalent Vaccine

M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA
T Lymphocyte Responses Elicited by Current Vaccines

Gary J. Nabel, Sanofi, USA
Criteria for Advancement of Novel Vaccine Candidates

William Snow, AIDS Vaccine Advocacy Coalition, USA
Short Talk: STEP-ing Forward: Community Perspectives on Communication and Decision-Making in the MRK-Ad5 Trials

Harriet L. Robinson, GeoVax Inc., USA
Short Talk: GeoVax Clade B DNA/MVA HIV/AIDS Vaccine is well Tolerated and Immunogenic when Administered to Healthy Seronegative Adults (HVTN 065 part A)

Laura Papagno, Laboratoire d'Immunologie Cellulaire, INSERM U543, France
Short Talk: Comprehensive Analysis of Virus-Specific CD8+ and CD4+ T Cells Provides Clues for the Failure of Therapeutic Immunization with ALVAC-HIV (vCP1452) Vaccine

19:15—20:15
Social Hour with Lite Bites

New Brunswick, Alberta, Cascade
19:30—22:00
Poster Session 1

New Brunswick, Alberta, Cascade

SATURDAY, MARCH 29

07:00—08:00
Breakfast

New Brunswick, Alberta, Cascade
08:00—11:00
Intracellular Events
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
* Robert W. Doms, University of Pennsylvania School of Medicine, USA
HIV Entry and its Inhibition

Katherine A. Jones, The Salk Institute, USA
Transcription Elongation by HIV-1 Tat Links to Histone Methylation

Frederic D. Bushman, University of Pennsylvania, USA
Retroviral DNA Integration: Mechanism and Consequences

Daria J. Hazuda, Merck Research Laboratories, USA
Inhibitors of HIV-1 Integrase: Lessons from the Analysis of Resistance Derived in vivo and in vitro

Eiji Morita, RIMD, Osaka University, Japan
Short Talk: Identification of ESCRT-I Binding Factors Required for Efficient HIV-1 Release

08:00—08:20
Special Lecture
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom C
Alan Bernstein, Canadian Institute for Advanced Research, Canada
Special Lecture

08:00—11:00
Optimization of Vectors and T Lymphocyte Responses
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom C
* Nina D. Russell, Bill & Melinda Gates Foundation, USA

Giuseppe Pantaleo, Centre Hospitalier Universitaire Vaudois, Switzerland
Novel Poxvirus Vectors

Danilo R. Casimiro, Aeras, USA
What's Next After STEP? Implications on Vaccine Design

Dan H. Barouch, Harvard Medical School/Beth Israel Deaconess Medical Center, USA
Novel Adenovirus Vector-Based Vaccines for HIV-1

Stephen C. De Rosa, University of Washington, Fred Hutchinson Cancer Research Center, USA
Short Talk: Kinetics of T Cell Responses to Vaccination for HIV with Heterologous DNA Prime-rAd5 Boost Contrasted with Homologous rAd5 Prime-Boost

Rama Rao Amara, Emory University, USA
Short Talk: Preexisting Immunity to Vaccinia Reduces the Frequency of SIV-Specific CCR-5+ve but not CCR-7+ve CD4 T Cells Elicited by a DNA/MVA Vaccine and Enhances the Control of SIV251 Challenge

09:20—09:40
Coffee Break

Van Horne Ballroom Foyer
11:15—13:00
Poster Setup

New Brunswick, Alberta, Cascade
13:00—22:00
Poster Viewing

New Brunswick, Alberta, Cascade
12:00—13:30
Hands-on Computer Session on Los Alamos Sequence/Immunology Databases
Maximum attendance: 60. Interested participants may sign up at the meeting on a first-come, first-serve basis.

Beatty/Coleman
Thomas K. Leitner, Los Alamos National Laboratory, USA

Bette Tina Marie Korber, Los Alamos National Laboratory, USA

14:30—16:30
Workshop 2: Aspects of Progression

* Bette Tina Marie Korber, Los Alamos National Laboratory, USA

Jason Ho, NIAID, National Institutes of Health, USA
HIV-Specific B Cells Are Enriched in a Dysfunctional Tissue-like Memory B-Cell Compartment in HIV-Infected Viremic Individuals

David M. Kuhrt, Maine Medical Center Research Institute, USA
Phenotypic Perturbation of the B Cell Compartment During Acute Simian Immunodeficiency Virus Infection

* Jason M. Brenchley, NIAID, National Institutes of Health, USA
Th17 Cells are Preferentially Depleted from GI Tract, but not BAL or Blood, of HIV-Infected Individuals

Pratip K. Chattopadhyay, National Institutes of Health, USA
Does T-Cell Function during Acute/Early HIV Predict Outcome?

Peter W. Hunt, University of California, San Francisco, USA
Inflammatory Consequences of Viral Control in HIV-infected Patients with Undetectable Plasma HIV RNA Levels in the Absence of Therapy

Paul de Bakker, Vertex Pharmaceuticals, USA
A Genome-Wide Association Study in HIV Elite Controllers to Identify Host Genetic Factors that Influence Viral Control in the Absence of Anti-Retroviral Therapy

14:30—16:30
Workshop 2: Mucosal/Innate Immunity

Van Horne Ballroom C
* M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA

* Karin Loré, Karolinska Institutet, Sweden

Kimberly Ann Schoenly, University of Pennsylvania, USA
Systemic and Mucosal Immune Responses Elicited by Electroporation Delivered Mucosal Targeting Chemokine DNA Vaccines in Mice and Macaques

David R. Kaufman, Merck Research Laboratories, USA
Systemic Vaccination with Hetrologous Recombinant Adenovirus Prime-Boost Regimens Elicits Potent and Durable Mucosal Immunity

Cornelia Gujer, Karolinska Institutet, Sweden
Dendritic Cell Mediated Support of Human B Cell Responses Via Toll-Like Receptor Ligands

Kathlyn Santos, NIAID, National Institutes of Health, USA
Immunomodulation of Human Dendritic Cells by MVA and Ad5 Vaccine Vectors

Elizabeth Rhee, Beth Israel Deaconess Medical Center, USA
Rare Serotype Recombinant Adenovirus Vaccine Vectors Elicit Expression of Type I Interferon

Salix Boulet, Université de Montréal, Canada
Increased Expression of KIR3DL1 Subtypes and HLA-B57 in HIV Exposed Uninfected (EU) versus HIV Susceptible Individuals

Patrice Debré, Hopital Pitie Salpetriere, France
A New Concept for HIV Vaccine Preventing CD4 T Cell Depletion

16:30—17:00
Coffee Available

Van Horne Ballroom Foyer
17:00—19:15
Restriction Factors
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
Felipe Diaz-Griffero, Albert Einstein College of Medicine, USA
Blocking Early Events in HIV-1 Infection

Ruzena Stranska, University of Massachusetts Medical School, USA
Short Talk: Heterokaryon Analysis Suggests the Existence of a Dominant Restriction to SIV Infection in Macrophages

* Michael H. Malim, King's College London, UK
APOBEC Proteins and Intrinsic Resistance to HIV Infection

Stuart J. Neil, King's College London, UK
Short Talk: Tetherin, A Novel Antiviral Inhibitpr of Retrovirus Release that is Targeted by the HIV-1 VPU Protein

Harmit S. Malik, Fred Hutchinson Cancer Research Center, USA
Viral Restriction: Evolutionary Signatures of the Arms-Race between Host and Virus

17:00—19:15
Prospects for Generating Broad Neutralizing Antibody Responses
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom C
* John R. Mascola, NIAID, National Institutes of Health, USA

Peter D. Kwong, NIAID, National Institutes of Health, USA
CD4-Binding-Site Antibodies: Prospects, Complications and Crystallographic Analyses

Munir Alam, Duke Human Vaccine Institute, USA
The Role of Hydrophobic CDRH3 Loops of the Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 in Binding gp41, Lipids and in HIV-1 Neutralization

Quentin J. Sattentau, Sir William Dunn School of Pathology, UK
Novel Formulation, Adjuvantation and Delivery Strategies for Inducing Env-Specific Antibodies

James E. Robinson, Tulane University Health Sciences Center, USA
Short Talk: SHIV-Infected Rhesus Macaques Develop Antibodies Recognizing Quaternary Epitope(s) Exposed on Autologous Virus Particles

Nicole A. Doria-Rose, NIAID, National Institutes of Health, USA
Short Talk: Frequency and Phenotype of HIV gp120-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies

19:15—20:15
Social Hour with Lite Bites

New Brunswick, Alberta, Cascade
19:30—22:00
Poster Session 2

New Brunswick, Alberta, Cascade

SUNDAY, MARCH 30

07:00—08:00
Breakfast

New Brunswick, Alberta, Cascade
08:00—11:00
Structure
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
Ian A. Wilson, The Scripps Research Institute, USA
HIV Neutralizing Antibody Structures

Kenneth H. Roux, Florida State University, USA
HIV Envelope Glycoproteins

Sriram Subramaniam, National Institutes of Health, USA
Electron Tomography of HIV-1 and SIV: Spike Architecture and Entry Mechanisms

* Wesley I. Sundquist, University of Utah School of Medicine, USA
Retroviral Budding

Reuben S. Harris, University of Minnesota, USA
Short Talk: Structure of the DNA Deaminase Domain of the HIV-1 Restriction Factor APOBEC3G

08:00—11:00
Protection Against Transmission of Mucosal Viruses: What Can Be Learned?
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom C
* Mario Roederer, NIAID, National Institutes of Health, USA

Janine T. Bryan, Merck, USA
HPV Vaccine

Harry B. Greenberg, Stanford University, USA
Rotavirus Pathogenesis and Vaccination-The Second Time is a Charm

Lawrence Corey, Fred Hutchinson Cancer Research Center, USA
The HSV-HIV Connection: What Similarities Exist for Vaccine Development

Maria Grazia Pau, Johnson & Johnson Inc., USA
Flu, TB

Meritxell Genescà, Health Sciences Research Institute Germans Trias i Pujol Foundation, Spain
Short Talk: SIV-specific CD8+ T Cells Mediated Protection from Uncontrolled Viral Replication after Vaginal Challenge in Live-Attenuated Immunized Rhesus Macaques

09:20—09:40
Coffee Break

Van Horne Ballroom Foyer
11:00—13:00
Poster Setup

New Brunswick, Alberta, Cascade
13:00—22:00
Poster Viewing

New Brunswick, Alberta, Cascade
14:30—16:30
Workshop 3: Mucosal/Innate Immunity and T/B Cell Immunology

Van Horne Ballroom AB
* Galit Alter, Ragon Institute of MGH, MIT and Harvard, USA

* John P. Moore, Weill Medical College of Cornell University, USA
The Mannose Moieties of gp120 Glycans Suppress the Antibody Response to gp120 in Mice via an MCLR- and IL-10-Dependent Mechanism

Elias A. Said, Université de Montréal, Canada
PD-1 Expression in Monocytes: Up-Regulated during HIV Infection and Induces IL10 Production

Appakkudal Anand, Ohio State University Medical Center, USA
HIV-1 Macrophage-Tropic gp120-Induced Migration of Dendritic Cells is Regulated by the Tyrosine Kinase, Pyk2

Shahin Ranjbar, Immune Disease Institute, USA
HIV-1 Replication is Differentially Regulated by Different Clinical Strains of Mycobacterium Tuberculosis

Evan S. Jacobs, Blood Systems Research Institute, USA
PDC Interaction with HIV-Infected Cells Results in Fusion and Loss of Function Leading to the Potential Depletion of PDC in vivo

Angela Meier, Harvard Medical School, Massachusetts General Hospital, USA
Gender Differences in the Activation of pDCs in Response to HIV-1-Encoded TLR7/8 Ligands

Joseph N. Brown, University of Florida, USA
HIV-1 Activates Macrophages Independent of Toll-like Receptors, a Potential Mechanism for Dysregulation of Innate Immunity

16:30—17:00
Coffee Available

Van Horne Ballroom Foyer
17:00—19:00
Viral Control (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom
* Dan H. Barouch, Harvard Medical School/Beth Israel Deaconess Medical Center, USA

Andrew J. McMichael, Oxford University, UK
Cellular Immune Responses before and during Early HIV Infection

Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA
Durable Control of HIV Replication

Douglas D. Richman, University of California, San Diego, USA
Neutralizing Antibody in the Control of HIV Infection

Galit Alter, Ragon Institute of MGH, MIT and Harvard, USA
Short Talk: Specific Expansion of Highly Functional KIR+ NK Cells during Acute HIV-1 Infection

19:00—20:00
Social Hour with Lite Bites

New Brunswick, Alberta, Cascade
19:30—22:00
Poster Session 3

New Brunswick, Alberta, Cascade

MONDAY, MARCH 31

07:00—08:00
Breakfast

New Brunswick, Alberta, Cascade
08:00—11:15
Interface Between Immunology and Vaccine Design (Joint)
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom
* M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA

Rafi Ahmed, Emory University School of Medicine, USA
CD8 T Cell Memory

David I. Watkins, University of Miami, Miller School of Medicine, USA
The Thorny Issue of Heterologous Challenge

Bali Pulendran, Emory University, USA
Modulating Vaccine Responses with Innate Immunity

Claire A. Chougnet, Cincinnati Children's Hospital Medical Center, USA
Interactions between Regulatory T Cells and HIV: A Complex Balancing Act

April L. Ferre, University of California, Davis, USA
Short Talk: Polyfunctional T-Cells in the Rectal Mucosa of HIV Controllers

Natalie A. Hutnick, University of Pennsylvania, USA
Short Talk: T-Cell Responses in Healthy Adults to Replication Deficient AdHu5 Vector

09:20—09:40
Coffee Break

Van Horne Ballroom Foyer
16:30—17:00
Coffee Available

Van Horne Ballroom Foyer
17:00—19:15
Drugs and Drug Resistance
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom AB
* Jeffrey D. Lifson, Leidos Biomedical Research, Inc., USA
Lasting Beneficial Consequences of Pharmacological Alteration of Virus/Host Balance in Primary SIV Infection

Joseph K. Wong, University of California, San Francisco, USA
Drug Resistance

Robin Shattock, Imperial College London, UK
New Developments in Design of Effective Microbicides

Nicoli Nattrass, University of Cape Town, South Africa
The Economics of Drug Delivery

17:00—19:00
Correlates of Immune Protection
Meeting has ended...abstracts no longer viewable online.

Van Horne Ballroom C
* John R. Mascola, NIAID, National Institutes of Health, USA

Louis J. Picker, Oregon Health & Science University, USA
Live Attenuated Vaccines

Robert Paul Johnson, Harvard Medical School, New England Primate Research Center, USA
Protection Against Mucosal SIV Transmission

Rafick-Pierre Sékaly, Case Western Reserve University, USA
Systems Biology Approaches to Understanding Memory T Cells Development and Defects

Qingsheng Li, University of Nebraska Center for Virology, USA
Short Talk: Divergent Host Transcriptional Profiles in Lymphatic Tissues of Sooty Mangabeys and Rhesus Macaques Infected with Simian Immunodeficiency Viruses

19:15—20:15
Social Hour with Lite Bites

New Brunswick, Alberta, Cascade
20:00—23:00
Entertainment

New Brunswick, Alberta, Cascade

TUESDAY, APRIL 1

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 5R13AI068352-03




We gratefully acknowledge additional support for this conference from:

Bill & Melinda Gates Foundation Merck Research Laboratories
Office of AIDS Research, NIH
Boehringer Ingelheim (Canada) Ltd.


We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Merck & Co., Inc.


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