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This meeting took place in 2008


Here are the related meetings in 2018:
Gene Control in Development and Disease (X6)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Regulatory Mechanisms in Eukaryotic Transcription (B4)


Organizer(s) Kevin Struhl and John T. Lis
February 3—8, 2008
Keystone Resort • Keystone, Colorado USA
Abstract Deadline: Oct 4, 2007
Late Abstract Deadline: Nov 2, 2007
Scholarship Deadline: Oct 4, 2007
Early Registration Deadline: Dec 4, 2007

Supported by the Director's Fund

Summary of Meeting:
Transcriptional regulatory mechanisms are central to many biological phenomena such as cell growth, development of multicellular organisms, response to environmental conditions, and disease. Critical subject areas to be address include (1) detailed structure-function analysis of the basic transcription machinery, (2) how transcriptional co-activators connect gene-specific activator proteins to the basic machinery, (3) the mechanism of transcriptional elongation and its coupling to mRNA processing, (4) the role of chromatin structure in transcriptional mechanisms, (5) the role of nuclear organization, (6) transcriptional silencing mechanisms including the involvement of RNAi, (7) various long-range effects on transcriptional activity, and (8) genome-wide and other functional genomic approaches. These research areas are interconnected at many levels, from detailed mechanistic issues to important biological phenomena. A major goal of the meeting is to provide an avenue for participants to learn about the latest conceptual and technical advances in eukaryotic transcription regulation.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, FEBRUARY 3

15:00—19:30
Registration

Longs Peak Foyer
18:30—19:30
Refreshments

Longs Peak Foyer
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Longs Peak
Robert G. Roeder, Rockefeller University, USA
Function of Diverse Coactivators in Transcriptional Regulation


MONDAY, FEBRUARY 4

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—11:00
Basic Transcriptional Mechanisms
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Stephen Buratowski, Harvard Medical School, USA

Steven Hahn, Fred Hutchinson Cancer Research Center, USA
Mechanisms of RNA Polymerase II Transcription Initiation and Activation

Karen Adelman, Harvard Medical School, USA
RNA Polymerase is Poised for Rapid Activation Across the Genome

James A. Goodrich, University of Colorado, USA
Regulation of the Early Steps of Transcription by ncRNAs

Michael Meisterernst, Institute of Molecular Tumor Biology, Germany
Short Talk: A Dynamic Model for Control of Transcription by General RNA Polymerase II Transcription Cofactors

Tamar Juven-Gershon, Bar-Ilan University, Israel
Short Talk: The Importance of the Downstream Core Promoter Element (DPE) in the Development of the Animal Body Plan

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00—13:00
Poster Setup

Grays Peak 1-3
13:00—22:00
Poster Viewing

Grays Peak 1-3
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Transcriptional Co-Activators
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Joan W. Conaway, Stowers Institute for Medical Research, USA

Kevin Struhl, Harvard Medical School, USA
Molecular Understanding of Epigenetics

Laszlo Tora, Institut de Genetique et de Biologie Moleculaire et Cellulaire, France
TBP and TBP2 (TRF3) Involved in Transcriptional Events Regulated by Oogenesis and Early Embryogenesis

Arnold J. Berk, University of California, Los Angeles, USA
Short Talk: Adenovirus Small e1a Drives Cell Cycling by Globally Re-Localizing Chromatin Modifying Complexes

Marc Timmers, University Medical Centre Utrecht, Netherlands
Short Talk: TFIID and Chromatin Modification

Laurie A. Stargell, Colorado State University, USA
Short Talk: Spn1 Regulates Chromatin-Remodeling Complexes during Transcriptional Activation by RNA Pol II

19:00—20:00
Social Hour with Lite Bites

Grays Peak 1-3
19:30—22:00
Poster Session 1

Grays Peak 1-3

TUESDAY, FEBRUARY 5

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—11:00
Transcriptional Elongation and Coupling to mRNA Processing
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Shelley L. Berger, University of Pennsylvania, USA

Stephen Buratowski, Harvard Medical School, USA
Suppression of Cryptic Transcription by Two CTD-Dependent Mechanisms

Joan W. Conaway, Stowers Institute for Medical Research, USA
Regulation of DUB Uch37 by the INO80 Complex and by the 19S Proteasome

Nicholas J. Proudfoot, University of Oxford, UK
Mechanism of Pre-mRNA 3’ End Formation: Interconnections with Gene Structure and Mitosis

Nevan J. Krogan, University of California, San Francisco, USA
Functional Insights on Transcriptional Regulation from Genetic and Protein-Protein Interaction Maps

David H. Price, University of Iowa, USA
Short Talk: The Termination Factor TTF2 is Involved in Mammalian Transcription-Coupled Repair

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00—13:00
Poster Setup

Grays Peak 1-3
13:00—22:00
Poster Viewing

Grays Peak 1-3
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
Role of Chromatin in Transcriptional Mechanisms
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Bing Ren, Ludwig Institute for Cancer Research, USA

Shelley L. Berger, University of Pennsylvania, USA
Post-Transcriptional Modifications of Histone H4 in Gametogenesis and Aging

Robert J. Sims, Constellation Pharmaceuticals, USA
The CTD of RNA Pol II is Regulated by Site-Specific Methylation

Jerry L. Workman, Stowers Institute for Medical Research, USA
Chromatin-Modifying Complexes and Histone Variants

Masami Horikoshi, University of Tokyo, Japan
Short Talk: From Histone Modification to Nuclesome Disassembly

François Robert, Institut de Recherches Cliniques de Montreal, Canada
Short Talk: Human H2A.Z Modulates Early Events in the Process of Transcription and is Required for Estrogen Receptor Signaling

19:15—20:15
Social Hour with Lite Bites

Grays Peak 1-3
19:30—22:00
Poster Session 2

Grays Peak 1-3

WEDNESDAY, FEBRUARY 6

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—11:00
Nuclear Organization and Transcription
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Peter B. Becker, University of Munich, Germany

Gordon L. Hager, NCI, National Institutes of Health, USA
Transcription Factor Dynamics and Global Chromatin Structure

Robert H. Singer, Albert Einstein College of Medicine, USA
Modeling the Synthesis and Behavior of mRNA

John T. Lis, Cornell University, USA
The Dynamics of Transcription Factors and Chromatin at Specific Loci upon Gene Activation

Michael Hampsey, Robert Wood Johnson Medical School, UMDNJ, USA
Short Talk: DNA Loops in RNA Polymerase II Transcription

Benoit Coulombe, Institut de recherches cliniques de Montréal, Canada
Short Talk: Proteomics Survey Identifies Novel Regulatory Factors That Target the Elongation Factor P-TEFb and RNA Polymerase II

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00—13:00
Poster Setup

Grays Peak 1-3
13:00—22:00
Poster Viewing

Grays Peak 1-3
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Transcriptional Silencing
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Barbara J. Meyer, University of California, Berkeley, USA

Danesh Moazed, Harvard Medical School, USA
Role of Histone Modifications and Non-Coding RNA in Heterochromatin Assembly

Michael R. Green, University of Massachusetts Medical Center, USA
Oncogene-Directed Epigenetic Silencing

Min Gyu Lee, University of Texas MD Anderson Cancer Center, USA
Short Talk: Crosstalk between H3K27 Demethylation and H3K4 Methylation for Gene Activation

19:00—20:00
Social Hour with Lite Bites

Grays Peak 1-3
19:30—22:00
Poster Session 3

Grays Peak 1-3

THURSDAY, FEBRUARY 7

07:00—08:00
Breakfast

Grays Peak 1-3
08:00—11:00
Long-Range Effects
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Richard A. Young, Whitehead Institute for Biomedical Research, USA

Job Dekker, University of Massachusetts Medical School, USA
Spatial Organization of Chromatin and Long-Range Gene Regulation

Edith Heard, Institut Curie, France
Cis and Trans Regulation during X Inactivation

Barbara J. Meyer, University of California, Berkeley, USA
X-Chromosome-Wide Repression through Dosage Compensation

Peter B. Becker, University of Munich, Germany
Dosage Compensation in Fruit Flies: Making the X a Special Chromosome

09:20—09:40
Coffee Break

Longs Peak Foyer
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Global Approaches
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Danesh Moazed, Harvard Medical School, USA

Richard A. Young, Whitehead Institute for Biomedical Research, USA
Regulatory Circuitry of Human Embryonic Stem Cells

Bing Ren, Ludwig Institute for Cancer Research, USA
Differential Roles of Promoters, Enhancers and Insulators in Cell-Type Specific Gene Expression

Michael P. Snyder, Stanford University School of Medicine, USA
Mapping Regulatory Networks in Yeast and Humans

Chia-Lin Wei, Genome Institute of Singapore, Singapore
Short Talk: Global Mapping of Chromatin Interactions and Transcription Networks Mediated by Pluripotent TFs in ES Cells

19:00—20:00
Social Hour with Lite Bites

Grays Peak 1-3
20:00—23:00
Entertainment

Grays Peak 1-3

FRIDAY, FEBRUARY 8

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13CA130251-01




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