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This meeting took place in 2009



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Emerging Themes in Tumor Suppressors: Function and Clinical Implications in the Post-Genomic Era (B1)


Organizer(s) Kun-Liang Guan, Eric R. Fearon and Stephen H. Friend
January 25—30, 2009
Sagebrush Inn & Suites • Taos, New Mexico USA
Abstract Deadline: Sep 25, 2008
Late Abstract Deadline: Oct 28, 2008
Scholarship Deadline: Sep 25, 2008
Early Registration Deadline: Nov 25, 2008

Supported by the Directors' Fund

Summary of Meeting:
This symposium will cover the recent exciting discoveries on tumor suppressors and related areas. The sessions, topics, and speakers have been chosen to reflect the fact that cancers arise from multiple defects in tumor suppressor pathways/networks. The pathways to be discussed at the meeting are among those most commonly altered in cancer cells, and where exciting results have emerged over the past few years and where considerable progress is expected. The talks will offer exciting new results from the speakers’ laboratories and it is expected that common biological themes will emerge in many sessions, such as the pleiotropic effects of tumor suppressor gene defects on multiple different cell phenotypes, and the likely cross-talk between tumor suppressor gene pathways that currently appear to be functionally distinct.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, JANUARY 25

15:00—19:30
Registration

Chamisa Lobby
18:30—19:30
Refreshments

Chamisa Lobby
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Stephen H. Friend, Sage Bionetworks, USA

Eric Schadt, Mount Sinai School of Medicine, USA
Networks as the Sensors and Drivers of Disease


MONDAY, JANUARY 26

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:15
p53 and ARF
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Stephen B. Baylin, Johns Hopkins University School of Medicine, USA

Scott W. Lowe, Memorial Sloan Kettering Cancer Center, USA
Identifying New Tumor Suppressors through in vivo RNA Interference Screens

Yukiko Hasumi, National Cancer Institute, National Institutes of Health, USA
Short Talk: Investigating the Role of the BHD Tumor Suppressor Gene in vivo; Early Embryonic Lethality and Increased Incidence of Kidney Tumor in BHD Heterozygous Null Mice

Charles J. Sherr, St. Jude Children's Research Hospital, USA
The Arf Tumor Suppressor: Gating Cellular Self-Renewal

Craig B. Thompson, Memorial Sloan Kettering Cancer Center, USA
Autophagy and Cancer - Cell Survival vs. Cell Death

Veronique T. Baron, vaccine research institute of sand iego, USA
Short Talk: Gain-of-Function Mutation of p53 Initiates a Positive Feedback Loop Involving EGR-1, EGF-R, and the ERK1/2 Pathway in Prostate Cancer Cells

Pier Paolo Pandolfi, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Aberrant PTEN/PI3K Signaling in Tumorigenesis

09:20—09:40
Coffee Break

Chamisa Lobby
11:00
On Own for Lunch

11:15—13:00
Poster Setup

Chamisa Ballroom 2
13:00—22:00
Poster Viewing

Chamisa Ballroom 2
16:30—17:00
Coffee Available

Chamisa Lobby
17:00—19:00
Epigenetics, Chromatin Modification and Tumor Suppressors
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Scott W. Lowe, Memorial Sloan Kettering Cancer Center, USA

Stephen B. Baylin, Johns Hopkins University School of Medicine, USA
Epigenetic Mechanisms of Tumor Suppressor Gene Inactivation

Yang Shi, Children's Hospital Boston, Harvard Medical School, USA
Histone Methylation

Manel Esteller, Belvitge Biomedical Research Institute (IDIBELL), Spain
Cancer Epigenomics

19:00—20:00
Social Hour with Lite Bites

Chamisa Ballroom 2
19:30—22:00
Poster Session 1

Chamisa Ballroom 2

TUESDAY, JANUARY 27

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:15
PTEN/FOXO/TSC/LKB
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Michael B. Kastan, St. Jude Children's Research Hospital, USA

Jihye Paik, Dana Farber Cancer Institute/ Harvard Medical School, USA
FoxOs in Cancer and Stem Cells

Bin Zhao, Zhejiang University, China
Short Talk: Tead Binding and WW Domains are both Required for the Growth Stimulation and Oncogenic Transformation Activity of YAP

Elizabeth Petri Henske, Brigham and Women's Hospital, USA
LAM and TSC Pathogenesis

Yang Liu, University of Michigan, Ann Arbor, USA
FOXP3 is an X-Linked Cancer Suppressor Gene

Arti Santhanam, National Cancer Institute at Frederick, USA
Short Talk: Novel Tumor Suppressor Pdcd4 Inhibits mRNA Translation Initiation to Prevent Tumorigenesis and Invasion

Senthil Kumar Muthuswamy, Ontario Cancer Institute, Canada
Cell Polarity and Tumor Suppression

09:20—09:40
Coffee Break

Chamisa Lobby
11:00
On Own for Lunch

11:15—13:00
Poster Setup

Chamisa Ballroom 2
13:00—22:00
Poster Viewing

Chamisa Ballroom 2
16:30—17:00
Coffee Available

Chamisa Lobby
17:00—19:00
Tumor Suppressors, Checkpoints and Genetic Instability
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Elizabeth Petri Henske, Brigham and Women's Hospital, USA

Lynda Chin, University of Texas MD Anderson Cancer Center, USA
Translating the Cancer Genome

Dina Dikovskaya, College of Life Sciences, University of Dundee, UK
Mechanisms for Tumour Predisposition by Mutations in Adenomatous Polyposis Coli

Michael B. Kastan, St. Jude Children's Research Hospital, USA
Molecular Controls of the ATM-p53 Pathway

19:00—20:00
Social Hour with Lite Bites

Chamisa Ballroom 2
19:30—22:00
Poster Session 2

Chamisa Ballroom 2

WEDNESDAY, JANUARY 28

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:00
Non-Coding RNAs in Tumor Suppression
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Sean J. Morrison, University of Texas Southwestern Medical Center, USA

Reuven Agami, Netherlands Cancer Institute, Netherlands
Cofactor Regulating p53 Tumor Suppressor Activity

Xiaotao Li, Baylor College of Medicine, USA
Short Talk: Regulation of p53 by the Proteasome Activator REGgamma

Carlo M. Croce, Ohio State University, USA
Non-Coding RNA in Oncogene and Tumor Suppression Function

Randall S. Johnson, University of Cambridge, UK
Inflammatory Cell VEGF Release: Angiogenesis as a Tumor Suppressor

Martijn Kedde, Netherlands Cancer Institute, Netherlands
Short Talk: Interplay between microRNAs and RNA Binding Proteins Regulate the p27 Tumor Suppressor

Yue Xiong, University of North Carolina at Chapel Hill, USA
Control of Stem and Progenitor Cell Cycle by INK4 Genes

09:20—09:40
Coffee Break

Chamisa Lobby
11:00
On Own for Lunch

11:00—13:00
Poster Setup

Chamisa Ballroom 2
13:00—22:00
Poster Viewing

Chamisa Ballroom 2
16:30—17:00
Coffee Available

Chamisa Lobby
17:00—19:00
Cancer Stem Cells and Tumor Suppressor Pathways
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Carlo M. Croce, Ohio State University, USA

Sean J. Morrison, University of Texas Southwestern Medical Center, USA
Hmga2 Increases the Self-Renewal of Fetal and Young Adult Stem Cells as Compared to Old Adult Stem Cells by Negatively Regulating p16Ink4a and p19Arf Expression

David Bilder, University of California, Berkeley, USA
New Insights into Drosophila Tumor Suppression

Ariel Ruiz i Altaba, University of Geneva Medical School, Switzerland
HEDGEHOG-GLI Signaling in Stem Cells and Cancer

19:00—20:00
Social Hour with Lite Bites

Chamisa Ballroom 2
19:30—22:00
Poster Session 3

Chamisa Ballroom 2

THURSDAY, JANUARY 29

07:00—08:00
Breakfast

Los Vaqueros
08:00—11:15
Tissue Context and Tumor Suppressor Function
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Yue Xiong, University of North Carolina at Chapel Hill, USA

Colleen A. Fordyce, University of California, San Francisco, USA
Epithelial-Stromal Interactions and Tumor Suppressors

Alice Hawley Berger, Beth Israel Deaconess Medical Center, USA
Short Talk: Identification of DOK Family Proteins as Lung Tumor Suppressors

Eileen P. White, Rutgers University, USA
Autophagy, Metabolic Stress and Genome Damage

Tian Xu, Yale University School of Medicine, USA
Cell Polarity and JNK Signaling in Drosophila Tumor Progression and Metastasis

Gutian Xiao, University of Pittsburgh Medical Center, USA
Short Talk: Epigenetic Repression of PDLIM2 in Cancer

Andrea I. McClatchey, Massachusetts General Hospital, USA
Membrane Organization in Receptor Tyrosine Kinase Signaling and Tissue Homeostasis

Kun-Liang Guan, University of California, San Diego, USA
The TSC-mTOR Pathway in Cell Growth Regulation

09:20—09:40
Coffee Break

Chamisa Lobby
11:15
On Own for Lunch

16:30—17:00
Coffee Available

Chamisa Lobby
17:00—19:00
Metabolism and Cancer
Meeting has ended...abstracts no longer viewable online.

Chamisa Ballroom 1
* Tian Xu, Yale University School of Medicine, USA

19:00—20:00
Social Hour with Lite Bites

Chamisa Ballroom 2
20:00—23:00
Entertainment

Chamisa Ballroom 2

FRIDAY, JANUARY 30

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13CA135833-01




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