Fairmont Hotel Vancouver Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2009



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Dissecting the Vasculature: Function, Molecular Mechanisms and Malfunction (J8)


Organizer(s) Stephanie Wengert Watts, Nancy J. Rusch and William F. Jackson
February 24—March 1, 2009
Fairmont Hotel Vancouver • Vancouver, British Columbia Canada
Abstract Deadline: Oct 23, 2008
Late Abstract Deadline: Nov 25, 2008
Scholarship Deadline: Oct 23, 2008
Early Registration Deadline: Dec 29, 2008

Supported by the Directors' Fund


Summary of Meeting:
The goal of this meeting is to present the most current research on the vasculature by breaking down the blood vessel into individual cells (endothelium, smooth muscle and nerve) and examine the function of organelles (nucleus, ER, plasma membrane) within each cell type. This work will be synthesized into the whole blood vessel, and a focus given to vessel dysfunction in hypertension and—as is highlighted by a concurrent meeting—diabetes. Workshops will support young investigators, and techniques specific to studying the vasculature. Attendees should take away an appreciation for the complexity and beauty of the vasculature.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, FEBRUARY 24

15:00—19:30
Registration

BC Foyer
18:30—19:30
Refreshments

Pacific Ballroom
19:30—20:30
Keynote Address (Joint)
Meeting has ended...abstracts no longer viewable online.

British Columbia Ballroom
* Ann Marie Schmidt, New York University Langone Medical Center, USA

* William F. Jackson, Michigan State University, USA

Joseph Loscalzo, Brigham and Women's Hospital, Harvard Medical School, USA
Redox Dysregulation in Vascular Disease


WEDNESDAY, FEBRUARY 25

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:00
Endothelial Cell Signaling Components
Meeting has ended...abstracts no longer viewable online.
The Endothelial Cell: New Molecules and Markers

British Ballroom
* Jonathan H. Jaggar, University of Tennessee College of Medicine, USA

* Michel Feletou, Institut de Recherche Servier, France

Brant M. Weinstein, NICHD, National Institutes of Health, USA
Regulation of Developmental Angiogenesis and Lymphangiogenesis

Mark S. Taylor, University of South Alabama College of Medicine, USA
Localized Calcium Signaling in the Endothelium

Lothar A. Blatter, Rush University Chicago, USA
Calcium and NFAT Signaling in Vascular Endothelial Cells

Luisa Iruela-Arispe, University of California, Los Angeles, USA
Intracrine VEGF Signaling in Endothelial Cells

Ralf Koehler, Phillips University Marburg, Germany
Short Talk: EDHF-Signaling and Arterial Blood Pressure in Mice Deficient of Endothelial KCa-Channels

Evgenia V. Gerasimovskaya, University of Colorado Denver, USA
Short Talk: PI3K and RhoA/ROCK Pathways Play a Critical Role in Hypoxia-Induced ATP Exocytosis and ATP-induced Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells

08:00—11:15
Glucose and Other Metabolites: Actions on Target Cells
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* Michael A. Brownlee, Albert Einstein College of Medicine, USA
Unifying Mechanisms and the Complications of Diabetes

Ann Marie Schmidt, New York University Langone Medical Center, USA
RAGE, Inflammation and the Complications of Diabetes

George L. King, Joslin Diabetes Center, USA
Protein Kinase C and the Complications of Diabetes

Paul Fernyhough, St Boniface Research Centre, Canada
Mitochondrial Stress and the Pathogenesis of Diabetic Neuropathy

Adriana Machado-Lima, University of São Paulo, Brazil
Short Talk: Glycated Albumin Isolated from Uncontrolled Type 1 and Type 2 Diabetes Mellitus Patients Impairs Cell Cholesterol Removal and Induces Lipid Accumulation in Macrophages

Bruce A. Perkins, University of Toronto, Canada
Short Talk: Excess Urinary Excretion of Markers of Glycation Predict Subsequent Early Renal Function Decline in Type 1 Diabetes

09:20—09:40
Coffee Break

BC Foyer
11:00
On Own for Lunch

11:15—13:00
Poster Setup

Pacific Ballroom
13:00—22:00
Poster Viewing

Pacific Ballroom
14:30—16:30
Workshop 1: Techniques (Joint)

British Columbia Ballroom
* Karen Lounsbury, University of Vermont, USA

Paul L. Hermonat, University of Arkansas for Medical Sciences, USA
Viral Gene Therapy Targeting the Vasculature

W. Gil Wier, University of Maryland School of Medicine, USA
Techniques for Imaging Signal Transduction in the Vasculature

Lloyd P. Aiello, Joslin Diabetes Center, USA
Designing Clinical Trials - The Fruits of Translational Research

16:30—17:00
Coffee Available

BC Foyer
17:00—19:00
Endothelial Cell Interactions and Targeting
Meeting has ended...abstracts no longer viewable online.
The Endothelial Cell: New Molecules and Markers

British Ballroom
* Mark S. Taylor, University of South Alabama College of Medicine, USA

* Richard A. Cohen, Boston University School of Medicine, USA

Sarah Y. Yuan, University of California, Davis, USA
Endothelial Junction and Vascular Permeability

Michel Feletou, Institut de Recherche Servier, France
The Endothelium as a Target for Drug Development

Wolfgang F. Graier, Medical University of Graz, Austria
Endothelial Mitochondria as Key Players for Endothelial Cell Function and Dysfunction

Caroline Cheng, Erasmus Medical Center, Netherlands
Short Talk: Functional Analysis of a Newly Identified Regulator of New Vessel Formation “EGIP”

17:00—19:00
Insulin Resistance and Actions
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
Insulin Actions and Cardiovascular Pathologies

Michael J. Quon, National Institutes of Health, USA
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction: From Cells to Humans

Nir Barzilai, Albert Einstein College of Medicine, USA
Aging and Insulin Resistance

Manuel Roman Benito, Universidad de Complutense, Spain
Short Talk: Compensated and Non-Compensated Insulin Resistance Induces Differential Cardiovascular Damage in Obese BATIRKO Mice

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
19:30—22:00
Poster Session 1

Pacific Ballroom

THURSDAY, FEBRUARY 26

07:00—08:00
Breakfast

Pacific Ballroom
07:00—08:00
Poster Setup

Pacific Ballroom
08:00—11:15
Vascular Smooth Muscle Cell Components and Communicators
Meeting has ended...abstracts no longer viewable online.
Vascular Smooth Muscle Cell Dissection: From Birth to Function

British Ballroom
* Julian H. Lombard, Medical College of Wisconsin, USA

* Keshari Thakali, Univ of Arkansas for Medical Sciences, USA

Mark W. Majesky, University of North Carolina at Chapel Hill, USA
Developmental Origins of Coronary Smooth Muscle

Jonathan H. Jaggar, University of Tennessee College of Medicine, USA
Mitochondrial Regulation of Arterial Calcium Signaling and Diameter

William F. Jackson, Michigan State University, USA
Vascular Ion Channels: Will the Key Players Please Stand Up?

Karen Lounsbury, University of Vermont, USA
Phenotype Switching in Vascular Smooth Muscle Cells: A Complex Interaction between Transcription Factors

Prasad V.G Katakam, Wake Forest University Health Sciences, USA
Short Talk: Impaired Mitochondria Dependent Vasodilation in Cerebral Arteries of Zucker Obese Rats with Insulin Resistance

Magdalena M. Szewczyk, McMaster University, Canada
Short Talk: Inhibitors Bioengineered to Inhibit Different Isoforms of Plasma Membrane Ca2+ Pumps in Vascular Smooth Muscle and Endothelium

08:00—11:15
Inflammation and Immunity: Links to Diabetes and Obesity
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Anthony W. Ferrante, Columbia University, USA
Inflammatory Mechanisms and Obesity

Ajay Chawla, University of California, San Francisco, USA
Macrophage Activation, Obesity and Insulin Resistance

* Douglas Golenbock, University of Massachusetts Medical School, USA
Toll Like Receptors - Linking Innate and Adaptive Immunity

Ishwarlal Jialal, University of California, Davis, USA
Diabetes (both Type 1 & 2) is a Pro-Inflammatory State?

Patricia W. Bedard, Pfizer, USA
Short Talk: CX3CR1 Contributes to Adipose Tissue Macrophage Infiltration and Insulin Resistance on a High Fat, High Sucrose Diet

Zhaoyun Zhang, Joslin Diabetes Center, USA
Short Talk: Overexpressing G6PD Reduces Oxidant Stress Induced by High Glucose via PKA Activation in Endothelial Cells

09:20—09:40
Coffee Break

BC Foyer
11:15—12:00
Lunch

Pacific Ballroom
12:00—14:30
Poster Session 2

Pacific Ballroom
14:30—16:30
Workshop 2: Funding for the Young Cardiovascular and Diabetes Investigator (Joint)

British Columbia Ballroom
* Ann Marie Schmidt, New York University Langone Medical Center, USA

* Nancy J. Rusch, University of Arkansas for Medical Sciences, USA

Cristina Rabadan-Diehl, NHLBI, National Institutes of Health, USA

Ronald Kohanski, NIA, National Institutes of Health, USA

Teresa Jones, NIDDK, National Institutes of Health, USA

R. Clinton Webb, Georgia Regents University, USA

Barbara Araneo, Novo Nordisk, USA

16:30—17:00
Coffee Available

BC Foyer
17:00—19:00
New Insights into Mechanisms of Vascular Contraction
Meeting has ended...abstracts no longer viewable online.
Vascular Smooth Muscle Cell Dissection: From Birth to Function

British Ballroom
* Lothar A. Blatter, Rush University Chicago, USA

* Frank Chip Brosius III, University of Michigan, USA

Richard J. Paul, University of Cincinnati College of Medicine, USA
It’s Not Just [Ca2+]i Anymore or Rho, ROS and Hypoxic Vasorelaxation

R. Clinton Webb, Georgia Regents University, USA
New Insights into Mechanisms of Vascular Contraction: STIM-1/Orai-1 Pathway and Vascular Dysfunction

W. Gil Wier, University of Maryland School of Medicine, USA
Genetically Encoded FRET-Based Sensors Allow Visualization of Signal Transduction in Individual Cells of Intact Arteries

Zachary P. Neeb, Indiana University School of Medicine, USA
Short Talk: Store-Operated Ca2+ Influx in Coronary Smooth Muscle Cells Predicts Coronary Atherosclerosis in the Metabolic Syndrome

17:00—19:00
Regeneration and Diabetes
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Douglas Zochodne, University of Calgary, Canada
Diabetes and Regenerative Failure of Peripheral Neurons

* Martin Friedlander, The Scripps Research Institute, USA
Cell-Based Therapies for Diabetic Retinopathy

Omaida C. Velazquez, University of Miami, Jackson Memorial Hospital, USA
The Potential Role of Hyperoxia and Endothelial Progenitor Cell Mobilization in Diabetic Wound Healing

Alex Chen, University of Pittsburgh, USA
Short Talk: Restoration of Endothelial Progenitor Cell Function with Manganese Superoxide Dismutase Gene Transfer in Type 2 Diabetic Wound Healing

19:00
On Own for Dinner


FRIDAY, FEBRUARY 27

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:15
Influences of Neighboring Cells on Vascular Smooth Muscle Function
Meeting has ended...abstracts no longer viewable online.
Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts

British Ballroom
* William F. Jackson, Michigan State University, USA

* David Robertson, Vanderbilt University Medical Center, USA

Jessica Andrea Filosa, Georgia Regents University, USA
Interpreting the Communication between Cerebral Microvessels and Astrocytes in the Brain

Ronald J. Korthuis, University of Missouri, USA
Postischemic Arteriolar Dysfunction is Dependent on Venular Leukocyte Adhesion and Mast Cells: Role of Cell-Cell Communication

Brant Isakson, University of Virginia, USA
Coordinated Function of Endothelial and Vascular Smooth Muscle Cells

Gregory Fink, Michigan State University, USA
Arteries and Veins: Substrates for Disparate But Integrated Sympathetic Control

Cécile Fligny, INSERM, France
Short Talk: Are Pericytes Responsible for Renal Interstitial Fibrosis through Transglutaminase-Mediated Collagen Assembly?

Lisa A. Lesniewski, University of Colorado, Boulder, USA
Short Talk: Age-Associated Endothelial Dysfunction is Associated with IKKbeta-Mediated Reductions in FoxO3a Activity and MnSOD Expression

08:00—11:15
Novel Targets and Treatments for Diabetes and its Complications
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Lloyd P. Aiello, Joslin Diabetes Center, USA
Novel Targets and Treatments for Diabetic Retinopathy and Macular Edema

Kumar Sharma, University of California, San Diego, USA
A Systems Biology Understanding of Diabetic Nephropathy Based on Novel Anti-Fibrosis Treatments and Biomarkers

* Ravichandran Ramasamy, New York University School of Medicine, USA
Aldose Reductase & Rage: Key Targets for Cardioprotective Interventions in Diabetes

Nobuyo Maeda, University of North Carolina, USA
Antioxidant Defense against Diabetic Cardiovascular Disease

Lokesh Kumar Bhatt, School of Pharmacy and Technology Management, India
Short Talk: Enhancement of MMP2 and MMP9 Inhibition in Presence of Aspirin, a COX Inhibitor: A New Therapeutic Approach in Treatment of Diabetic Neuropathy

Jia Liu, Joslin Diabetes Center, USA
Short Talk: Plasma Kallikrein Exacerbates Intracerebral Hemorrhage Expansion in Diabetic Rats

09:20—09:40
Coffee Break

BC Foyer
11:15
On Own for Lunch

11:15—13:00
Poster Setup

Vancouver Island Room
13:00—22:00
Poster Viewing

Pacific Ballroom
16:30—17:00
Coffee Available

BC Foyer
17:00—19:00
Synthesis of the Whole Vessel
Meeting has ended...abstracts no longer viewable online.
Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts

British Ballroom
* Gregory Fink, Michigan State University, USA

* Nancy J. Rusch, University of Arkansas for Medical Sciences, USA

David Robertson, Vanderbilt University Medical Center, USA
Human Phenotypes and Animal Knockout Models of Genetic Autonomic Disorders

Paul L. Hermonat, University of Arkansas for Medical Sciences, USA
Viral Delivery of Therapeutic Genes for Vascular Pathologies

David D. Gutterman, Medical College of Wisconsin, USA
Human Microvascular Function in Disease: Mechanistic Insights

Hema Raina, University of Maryland, USA
Short Talk: Sympathetic Nerve Activity Enhances, and Endothelium Inhibits, the Vasoconstrictor Effect of Low-Dose Ouabain

17:00—19:00
Cellular Mechanisms, Shaping the Nature and Severity of Complications
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
Erwin P. Böttinger, Mount Sinai School of Medicine, USA
Impact of Podocyte Injury in Diabetes

Thomas M. Coffman, NUS Duke SIngapore, Singapore
Impact of Hypertension and the Renin-Angiotensin System

* Geoffrey C. Gurtner, Stanford University, USA
Impaired Neovascularization in Diabetes and Aging

Sandeep Raha, Hamilton Health Services, Canada
Short Talk: Maternal Obesity Results in Placental Mitochondrial Dysfunction and Compromised Neonatal Health

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
19:30—22:00
Poster Session 3

Pacific Ballroom

SATURDAY, FEBRUARY 28

07:00—08:00
Breakfast

Pacific Ballroom
08:00—11:15
Hypertension and Angiogenesis - Responses to Vascular Injury/Genomics - Disease Models and Human Genomics (Joint)
Meeting has ended...abstracts no longer viewable online.
Mechanisms of Vascular Pathologies: Diabetes and Hypertension

British Columbia Ballroom
* Ronald J. Korthuis, University of Missouri, USA

* Thomas M. Coffman, NUS Duke SIngapore, Singapore

Susan Quaggin, Northwestern University, USA
Angiogenesis and Diabetic Nephropathy

Maria B. Grant, University of Florida, USA
Vascular Repair Strategies for Diabetic Retinopathy- Mobilization and Differentiation of Hematopoietic Stem Cell by IGFBP-3

Geert W. Schmid-Schönbein, University of California, San Diego, USA
A Molecular Mechanism for Blood Pressure Elevation, Type II Diabetes, Immune Suppression and Microvascular Rarefaction in the Spontaneously Hypertensive Rat

Frank Chip Brosius III, University of Michigan, USA
Flipped Signaling: Consequences of Altered Glucose Transporter Expression in Vascular Cells

Julia V. Busik, Michigan State University, USA
Short Talk: Inhibition of Sphingomyelinases Protects from Inflammation, Vascular Degeneration and Neovascularization in Retinopathy Animal Models

David A. Antonetti, University of Michigan, USA
Short Talk: Atypical PKC Inhibitors Block both VEGF and TNF alpha Induced Endothelial Permeability

09:20—09:40
Coffee Break

BC Foyer
11:15
On Own for Lunch

16:30—17:00
Coffee Available

BC Foyer
17:00—19:00
Mechanisms and Targeted Treatment of Vascular Pathologies: Focus on Hypertension
Meeting has ended...abstracts no longer viewable online.
Mechanisms of Vascular Pathologies: Diabetes and Hypertension

British Ballroom
* R. Clinton Webb, Georgia Regents University, USA

* David D. Gutterman, Medical College of Wisconsin, USA

Andrea D. Eckhart, Thomas Jefferson University, USA
Novel Mouse Models for Studying Vascular Contributions to Hypertension

Nancy J. Rusch, University of Arkansas for Medical Sciences, USA
Ion Channel Expression and Function in Hypertension

Richard A. Cohen, Boston University School of Medicine, USA
Redox Regulation of SERCA in Diabetic Vascular Disease

Julian H. Lombard, Medical College of Wisconsin, USA
Short Talk: Endothelial Dysfunction and Paradoxical Increase in Vascular Oxidative Stress with Angiotensin II Suppression

17:00—19:00
Genetics and Epigenetics
Meeting has ended...abstracts no longer viewable online.

Columbia Ballroom
* John Sedor, Case Western Reserve School of Medicine, USA
Genetics of Diabetic Nephropathy

Rama Natarajan, Beckman Research Institute of City of Hope, USA
Epigenetics, Metabolic Memory, Inflammation and Diabetic Complications

Juro Sakai, University of Tokyo, Japan
Short Talk: PPARgamma/RXRalpha Heterodimer Induces Histone Modification Enzyme PR-Set7/Setd8 and Promotes Adipogenesis through a Positive Feedback Loop

Monika A. Niewczas, Joslin Diabetes Center, USA
Short Talk: TNF alpha Related Markers Predict Glomerular Filtration Rate (GFR) Decline but not an Increase in Urinary Albumin Excretion in Patients with Early Diabetic Nephropathy: Results of a Prospective Study

19:00—20:00
Social Hour with Lite Bites

Pacific Ballroom
20:00—23:00
Entertainment

Pacific Ballroom

SUNDAY, MARCH 1

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 5R13DK076500-03




We gratefully acknowledge additional support for this conference from:


American Heart Association's Council on Arteriosclerosis, Thrombosis and Vascular Biology


American Heart Association's Council on Basic Cardiovascular Sciences


We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Institut de Recherches Servier


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Cell Press

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676