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This meeting took place in 2009



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Frontiers in Reproductive Biology and Regulation of Fertility (B5)


Organizer(s) Sudhansu K. Dey, Martin M. Matzuk and Kelle H. Moley
February 1—6, 2009
Hilton Santa Fe Historic Plaza Hotel • Santa Fe, New Mexico USA
Abstract Deadline: Oct 1, 2008
Late Abstract Deadline: Oct 30, 2008
Scholarship Deadline: Oct 1, 2008
Early Registration Deadline: Dec 1, 2008

Supported by the Directors' Fund

Summary of Meeting:
Sexual reproduction is a complex and highly regulated process essential for successful propagation and diversification of genetic complements, beginning with germ cell development and completing with birth of live young. For successful reproduction, a plethora of events including gametogenesis, ovulation, fertilization, implantation, and placentation requires precise regulation; the success of each go-ahead event is dependent on the accomplishment of the preceding event. Research on these events and their coordination has been translated into clinical practice, particularly for enhancing successes in fertility clinics, controlling gynecological diseases and developing contraceptives. This meeting is designed to bring together a diverse group of leaders, established and rising in the field, who study the complex regulation of reproduction and related developmental processes. The speakers and participants will comprise a group that uses a variety of model systems to better understand the processes relevant to human and animal reproduction and fertility regulation.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, FEBRUARY 1

15:00—19:30
Registration

Promenade
18:30—19:30
Refreshments

Promenade
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Kelle Moley, Washington University in St. Louis, USA
Introduction of Keynote Speaker

Janet Rossant, Hospital for Sick Children, Canada
Stem Cells and Early Lineage Development


MONDAY, FEBRUARY 2

07:00—08:00
Breakfast

Chamisa
08:00—11:00
Meiosis, Germ Cell Renewal and Differentiation
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
David C. Page, Whitehead Institute for Biomedical Research, USA
A Combination of Germ-Cell-Intrinsic and Extrinsic Factors Governs Meiotic Initiation in Mouse Embryos

Yumiko Saga, National Institute of Genetics, Japan
Nanos2 Promotes Sexual Differentiation of Male Germ Cells

* Tim Schedl, Washington University, USA
Systematic Identification of MPK-1 ERK Substrates Functioning in C. elegans Germ Cell Development

Satoshi Tsukamoto, National Institute of Radiological Sciences, Japan
Role of Autophagy during Early Embryogenesis in Mice

09:20—09:40
Coffee Break

Promenade
11:00
On Own for Lunch

11:00—13:00
Poster Setup

Mesa C
13:00—22:00
Poster Viewing

Mesa C
16:30—17:00
Coffee Available

Promenade
17:00—19:00
Female Reproductive Tract Morphogenesis
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* David C. Page, Whitehead Institute for Biomedical Research, USA

Richard R. Behringer, University of Texas MD Anderson Cancer Center, USA
Development of the Female Reproductive Tract

Thomas Edward Spencer, Washington State University, USA
Postnatal Uterine Morphogenesis: Strategies and Insights from Domestic Animals

Francesco J. DeMayo, Baylor College of Medicine, USA
Developmental Pathways Regulating Uterine Function

Shinichi Miyagawa, Kumamoto University, Japan
Short Talk: Identification of Genetic Cascade for External Genital Development

19:00—20:00
Social Hour with Lite Bites

Mesa C
19:30—22:00
Poster Session 1

Mesa C

TUESDAY, FEBRUARY 3

07:00—08:00
Breakfast

Chamisa
07:00—08:00
Poster Setup

Mesa C
08:00—11:00
Testicular Biology and Fertilization
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Michael D. Griswold, Washington State University, USA

Kate Loveland, Monash Institute of Medical Research, Australia
Activin Signaling in the Testis: Key Target Genes and Physiological Outcomes

Michael D. Griswold, Washington State University, USA
Retinoic Acid and the Cycle of the Seminiferous Epithelium

Erika Matunis, Johns Hopkins University School of Medicine, USA
Stem Cell Niches and Testicular Development

Jurrien Dean, NIDDK, National Institutes of Health, USA
Evolving Paradigms of Sperm-Egg Recognition in Mouse Fertilization

Yeunhee Kim, Cornell University, USA
Short Talk: Production of Donor-Derived Sperm after Spermatogonial Stem Cell Transplantation in the Dog

09:20—09:40
Coffee Break

Promenade
11:00—12:00
Lunch

Mesa C
12:00—14:30
Poster Session 2

Mesa C
12:00—17:00
Poster Viewing

Mesa C
16:30—17:00
Coffee Available

Promenade
17:00—19:15
Ovarian Biology and Oogenesis
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Martin M. Matzuk, Baylor College of Medicine, USA

John J. Eppig, The Jackson Laboratory, USA
Signaling Pathways Mediating Oocyte Control of Cumulus Cell Metabolism

Stephanie A. Pangas, Baylor College of Medicne, USA
Signaling through SMAD Proteins in the Ovary

Richard L. Stouffer, Oregon National Primate Research Center, USA
Molecular Analyses of Periovulatory Events in the Primate Follicle: From Microarray Assays to in Vivo Manipulation

Ankur K. Nagaraja, Baylor College of Medicine, USA
Short Talk: MicroRNAs in the Mammalian Ovary and Ovarian Cancer

Agnieszka Jedrusik, Wellcome Trust/Cancer Research UK Gurdon Institute, UK
Short Talk: Role of Cdx2 in Cell Fate Determination

19:15
On Own for Dinner


WEDNESDAY, FEBRUARY 4

07:00—08:00
Breakfast

Chamisa
08:00—11:00
Preimplantation Biology
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Kelle Moley, Washington University in St. Louis, USA
Energy Metabolism in Preimplantation Embryos

Magdalena Zernicka-Goetz, University of Cambridge, UK
Origins of Pluripotent ICM and Trophectoderm and Molecular Mechanisms behind their Specification

Mellissa Mann, Children's Health Research Institute, Canada
Susceptibility of Genomic Imprinting to Assisted Reproductive Technology

Toshihiko Fujimori, National Institute for Basic Biology, Japan
Analysis of Cell Behaviors during Preimplantation Mouse Development

Mylene W. M. Yao, Stanford University School of Medicine, USA
Short Talk: The Dynamic Gene Regulatory Network and Reprogramming in the Early Embryo

09:20—09:40
Coffee Break

Promenade
11:00
On Own for Lunch

16:30—17:00
Coffee Available

Promenade
17:00—19:00
Endocrine Disruptors, Environment and Epigenetics
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Selvaraj G. Nataraja, EMD Serono Research Institute, USA

Patricia Hunt, Washington State University, USA
Estrogens and the Oocyte: Can Environmental Factors Influence Female Reproductive Potential?

Michael K. Skinner, Washington State University, USA
Epigenetic Transgenerational Actions of Endocrine Disruptors on Reproduction and Disease: The Ghosts in Your Genes

Carmen J. Williams, National Institute of Environmental Health Sciences, USA
Short Talk: Neonatal Genistein Exposure Disrupts Adult Female Reproductive Tract Support of Preimplantation Embryo Development and Implantation

Shannon M. Hawkins, Baylor College of Medicine, USA
Short Talk: The Role of MicroRNAs in Uterine Dysfunction

Jihoon Kim, KAIST, South Korea
Short Talk: DNA Methylation Status of Imprinted Genes during Human Embryonic Stem Cell Differentiation

19:00—20:00
Social Hour with Lite Bites

Mesa C
20:00—22:00
Workshop: Genetics and Epigenetics of Reproduction

Mesa A-B
* Wendy P. Robinson, University of British Columbia, Canada
Epigenetic Profiling in the Human Placenta using the Illumina GoldenGate Methylation Panel

Joan K. Riley, Washington University, USA
Inhibition of GAPDH Leads to the Inactivation of S6K1 and Decreased Survival via Elevated ROS Production

Mana Parast, University of California, San Diego, USA
Hypoxia Inhibits PPARgamma-Induced Labyrinthine Differentiation of Mouse Trophoblast Stem Cells

Zhilin Liu, Baylor College of Medicine, USA
Genes in Sterol and Lipid Biosynthetic Pathways are Targets of FSH and FOXO1 Regulation in Granulosa Cells: Evidence from Cells Expressing Mutant Forms of FOXO1

Rebecca Marie Harris, Northwestern University, USA
Identification of Novel Genes Required for Spermatogenesis through Genome-Wide Mutagenesis with N-ethyl-N-nitrosourea

Masahito Ikawa, Osaka University, Japan
ER Chaperones and Sperm Fertility


THURSDAY, FEBRUARY 5

07:00—08:00
Breakfast

Chamisa
08:00—11:00
Pathways Governing Conceptus-Endometrial Dialogue
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Sudhansu K. Dey, Cincinnati Children's Hospital Medical Center, USA

John P. Lydon, Baylor College of Medicine, USA
Importance of Steroid Receptor Coregulator-2 in Female Reproductive Biology: Insights from Experimental Mouse Genetics

Haibin Wang, Chinese Academy of Sciences, China
Lipid Signaling in Embryo-Uterine Crosstalk

Carlos Simon, Fundacion IVI, Spain
Pathways Governing Human Endometrial Receptivity

Bruce Murphy, University of Montreal, Canada
The Enigma of Embryonic Diapause

Yasushi Hirota, Cincinnati Children's Hospital Medical Center, USA
Short Talk: Uterine Deletion of p53 Confers Compromised Decidualization and Induces Preterm Labor

09:20—09:40
Coffee Break

Promenade
11:00
On Own for Lunch

16:30—17:00
Coffee Available

Promenade
17:00—19:15
Biology of Placentation
Meeting has ended...abstracts no longer viewable online.

Mesa A-B
* Bruce Murphy, University of Montreal, Canada

Susan J. Fisher, University of California, San Francisco, USA
Formation of an Immunotolerant Uterine Niche for Human Placental Cytotrophoblasts

Vikki M. Abrahams, Yale University School of Medicine, USA
The Role of Pattern Recognition Receptors in Trophoblast Function

Miguel Constância, University of Cambridge, UK
Genomic Imprinting, Fetal Growth and the Allocation of Maternal Resources

Manyu Li, University of North Carolina-Chapel Hill, USA
Short Talk: Adrenomedullin Signaling at the Maternal-Fetal Interface

Nathan M. Hunkapiller, University of California, San Francisco, USA
Short Talk: Notch Expression and Function during Placental Vascular Remodeling

19:00—20:00
Social Hour with Lite Bites

Mesa C
20:00—23:00
Entertainment

Mesa C

FRIDAY, FEBRUARY 6

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13ES017382-01




We gratefully acknowledge additional support for this conference from:

Burroughs Wellcome Fund
EMD Serono, Inc.

Lalor Foundation
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Cell Press
Society for the Study of Reproduction


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676