Fairmont Chateau Whistler Floorplan

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This meeting took place in 2009



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Stem Cell Niche Interactions (D5)


Organizer(s) Markus Grompe and Margaret A. Goodell
April 21—26, 2009
Fairmont Chateau Whistler • Whistler, British Columbia Canada
Abstract Deadline: Dec 22, 2008
Late Abstract Deadline: Jan 26, 2009
Scholarship Deadline: Dec 22, 2008
Early Registration Deadline: Feb 23, 2009

Supported by the Directors' Fund

Summary of Meeting:
Embryonic stem cells are pluripotent precursors able to differentiate into the many cell types of the body. Adult or tissue stem cells are undifferentiated but lineage specific precursor cells able to proliferate long term while producing daughters that maintain the undifferentiated state (self-renew) and daughters that differentiate into specific cell types. In addition to their intrinsic interest for developmental biology, both kinds of stem cells have great promise for tissue renewal and regenerative medicine. Much has been learned in the past year about the mechanisms that maintain and induce stem cell pluripotency, the mechanisms that control differentiation, and the molecular regulation of stemness and self-renewal. Interactions between stem cells and their niches regulate self-renewal versus differentiation of adult stem cells and key signals from surrounding cells may organize fate decisions in space and time to pattern early embryonic development and differentiation of specific cell types. Understanding of the fundamental biology of embryonic and adult stem cells is being translated into development of “artificial niches” and conditions for controlling cell proliferation and differentiation. This meeting will bring together stem cell scientists from diverse model systems and backgrounds. All career levels will be represented. Current opportunities and challenges in the field will be highlighted in an atmosphere of informal exchange, facilitating new ideas and collaborations towards meeting the next great challenges in the field.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, APRIL 21

15:00—19:30
Registration

Macdonald Foyer
18:30—19:30
Refreshments

Macdonald Foyer
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* Markus Grompe, Oregon Health & Science University, USA

Sean J. Morrison, University of Texas Southwestern Medical Center, USA
The Regulation of Hematopoietic Stem Cell Self-Renewal


WEDNESDAY, APRIL 22

07:00—08:00
Breakfast

Macdonald Ballroom
08:00—11:15
Control of Stem Cell Differentiation
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* James A. Thomson, Morgridge Institute for Research, University of Wisconsin, USA

Deepak Srivastava, Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
MicroRNA Regulation of Cardiac Cell Fate Decisions

Ronald D. McKay, Lieber Institute for Brain Development, USA
Neural Lineages

Didier Stainier, Max Planck Institute for Heart and Lung Research, Germany
Endodermal Organ Development and Regeneration in Zebrafish

Gordon M. Keller, University Health Network, MaRS Centre, Canada
Cardiovascular Development from Mouse and Human Pluripotent Stem Cells

Jolly Mazumdar, University of Pennsylvania, USA
Short Talk: O2 Regulates Stem Cells through Wnt/beta-catenin Signaling

Fabio M.V. Rossi, University of British Columbia, Canada
Short Talk: Muscle Injury Activates Fibro/Adipogenic Progenitors that Provide a Transient Pro-Differentiation Niche for Myogenic Cells

09:20—09:40
Coffee Break

Macdonald Foyer
11:15
On Own for Lunch

11:15—13:00
Poster Setup

Macdonald Ballroom
13:00—22:00
Poster Viewing

Macdonald Ballroom
16:30—17:00
Coffee Available

Macdonald Foyer
17:00—19:00
Novel Sources of Pluripotent Cells
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* Ronald D. McKay, Lieber Institute for Brain Development, USA

Shoukrat Mitalipov, Oregon Health & Science University, USA
Pluripotent Stem Cells Derived by Somatic Cell Nuclear Transfer and Parthenogenesis

James A. Thomson, Morgridge Institute for Research, University of Wisconsin, USA
Human Induced Pluripotent Stem Cells Derived with Episomal Vectors

Timm Schroeder, ETH Zürich, Switzerland
Tracking Stem Cell Behavior at the Single Cell Level: New Tools for Old Questions

Robert David, Universität Rostock, Germany
Short Talk: Generation of Distinct Cardiovascular Cell Types from Pluripotent Stem Cells via Directed Forward Programming

19:00—20:00
Social Hour with Lite Bites

Macdonald Ballroom
19:30—22:00
Poster Session 1

Macdonald Ballroom

THURSDAY, APRIL 23

07:00—08:00
Breakfast

Macdonald Ballroom
07:00—08:00
Poster Setup

Macdonald Ballroom
08:00—11:15
Transcriptional and Epigenetic Regulation of Embryonic Stem Cell Fate
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* Gordon M. Keller, University Health Network, MaRS Centre, Canada

Yehudit Bergman, Hebrew University Medical School, Israel
Silencing of Embryonically-Specific Genes

Paul A. Khavari, Stanford University, USA
Epigenetic Regulation of Epidermal Self-Renewal and Differentiation

Thomas P. Zwaka, Icahn School of Medicine at Mount Sinai, USA
Ronin Controls a Unique Genetic Program Involved in the Perpetuity of Mouse Embryonic Stem Cells

Robert E. Braun, The Jackson Laboratory, USA
Short Talk: The Germline Stem Cell Niche Is Required for Fetal Stem Progenitor Cells and for Teratoma Formation

Cédric Blanpain, Universite Libre de Bruxelles, Belgium
Short Talk: Identification of the Cell Lineage at the Origin of Basocelullar Carcinoma

09:20—09:40
Coffee Break

Macdonald Foyer
11:15—12:00
Lunch

Macdonald Ballroom
12:00—14:30
Poster Session 2

Macdonald Ballroom
12:00—19:00
Poster Viewing

Macdonald Ballroom
16:30—17:00
Coffee Available

Macdonald Foyer
17:00—19:00
Asymmetric Cell Division
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* Allan C. Spradling, HHMI/Carnegie Institute, USA

Chris Q. Doe, University of Oregon, USA
Intrinsic and Extrinsic Cues Regulating Neuroblast ACD

Yukiko M. Yamashita, University of Michigan, Ann Arbor, USA
Asymmetric Stem Cell Divisions in the Drosophila Testis

Shahragim Tajbakhsh, Institut Pasteur, France
Skeletal Muscle Stem Cell Properties and Polarized Cell Divisions

Ellen J. Ward, University of Washington, USA
Short Talk: bantam miRNA is Required for Germline Stem Cell Division and Maintenance in the Drosophila Ovarian Niche

19:00
On Own for Dinner


FRIDAY, APRIL 24

07:00—08:00
Breakfast

Macdonald Ballroom
08:00—11:00
Tissue Specific Stem Cells I
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* Timm Schroeder, ETH Zürich, Switzerland

Stephen Badylak, University of Pittsburgh, USA
Biologic Scaffolds to Recreate the Regenerative Niche

Jill Helms, Stanford University School of Medicine, USA
Enhancing Bone Healing via Wnt-Protein Mediated Activation of Endogenous Stem Cells

Helen M. Blau, Stanford University, USA
Adult Stem Cell Behavior in Bioengineered Niches

Hans C. Clevers, Hubrecht Institute, Netherlands
Wnt, Lgr5 Stem Cells and Colon Cancer

Hans-Willem E. Snoeck, Columbia University Medical Center, USA
Short Talk: Quantitative Traits in Hemotopoiesis

09:20—09:40
Coffee Break

Macdonald Foyer
11:00
On Own for Lunch

11:00—13:00
Poster Setup

Macdonald Ballroom
13:00—22:00
Poster Viewing

Macdonald Ballroom
16:30—17:00
Coffee Available

Macdonald Foyer
17:00—19:00
Clinical Applications of Stem Cells and Artificial Niches
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* Helen M. Blau, Stanford University, USA

Markus Grompe, Oregon Health & Science University, USA
Regeneration in the Adult Liver: Stem Cells or Mature Hepatocytes?

Yann Barrandon, École Polytechnique Fédérale de Lausanne, Switzerland
Manipulating Epithelial Stem Cell Potency

Aileen Anderson, University of California, Irvine, USA
Stem Cell Transplantation in Spinal Cord Injury

Eric Lagasse, University of Pittsburgh, USA
Short Talk: Rescue of Lethal Hepatic Failure by Functional Ectopic Liver in Lymph Nodes

19:00—20:00
Social Hour with Lite Bites

Macdonald Ballroom
19:30—22:00
Poster Session 3

Macdonald Ballroom

SATURDAY, APRIL 25

07:00—08:00
Breakfast

Macdonald Ballroom
08:00—11:00
Tissue Specific Stem Cells II
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* Haifan Lin, Yale University, USA

Allan C. Spradling, HHMI/Carnegie Institute, USA
The Dynamic Follicle Stem Cell Niche

Shosei Yoshida, National Institute for Basic Biology, Japan
Spermatogenic Stem Cell System and its Niche in the Mouse Testis

Margaret A. Goodell, Baylor College of Medicine, USA
Regulation of Hematopoietic Stem Cells

Chutima Noi Talchai, Columbia University, USA
Short Talk: Foxo1 Controls Renewal of Pancreatic Endocrine Progenitors, and Beta Cell Formation

Tudorita (Doina) Tumbar, Cornell University, USA
Short Talk: Distinct Self-Renewal and Differentiation Phases in the Niche of Infrequently Dividing Hair Follicle Stem Cells

09:20—09:40
Coffee Break

Macdonald Foyer
11:15
On Own for Lunch

16:30—17:00
Coffee Available

Macdonald Foyer
17:00—19:00
Non-Coding RNAs and Cell Fate Control
Meeting has ended...abstracts no longer viewable online.

Macdonald Ballroom
* Margaret A. Goodell, Baylor College of Medicine, USA

Haifan Lin, Yale University, USA
Piwis and piRNAs in Germline Stem Cell Development

Soo-Kyung Lee, Oregon Health & Science University, USA
The Role of microRNAs and Small C-Terminal Phosphatases in Nervous System Development

Linheng Li, Stowers Institute for Medical Research, USA
Real Time Imaging the Functional HSC Niche

Xuting Rebecca Sheng, Johns Hopkins School of Medicine, USA
Short Talk: Live Imaging of Drosophila Spermatogonia Dedifferentiating into Germline Stem Cells

19:00—20:00
Social Hour with Lite Bites

Macdonald DEF
20:00—23:00
Entertainment

Macdonald DEF

SUNDAY, APRIL 26

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HD061141-01




We gratefully acknowledge additional support for this conference from:

Cell Signaling Technology, Inc. JDRF
The Company of Biologists Ltd
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Cell Press

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676