Beaver Run Resort Floorplan

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This meeting took place in 2009



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Epigenetics, Development and Human Disease (A1)


Organizer(s) Anne Ferguson-Smith and Steven Henikoff
January 5—10, 2009
Beaver Run Resort • Breckenridge, Colorado USA
Abstract Deadline: Sep 15, 2008
Late Abstract Deadline: Oct 8, 2008
Scholarship Deadline: Sep 15, 2008
Early Registration Deadline: Nov 5, 2008

Supported by the Directors' Fund

Summary of Meeting:
This meeting aims to provide a stimulating forum for exploring the epigenetic control of genome function illustrated through the regulation of a variety of biological processes in a range of model organisms. The role of factors influencing chromatin organization and chromosome architecture, and the dynamic changes in epigenetic state that regulate development, are two well-established but fast-moving areas that will be covered. The dynamic nature of epigenetic states renders them both adaptable and vulnerable; this will be explored in sessions considering the influence of the environment on epigenetic control, and the causes and consequences of epigenetic change in disease. We anticipate that the data presented will allow evolutionary insights and functional comparison of epigenetic mechanisms in different organisms and systems, resulting in the integration of ideas to generate new concepts and a deeper understanding in this field.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


MONDAY, JANUARY 5

15:00—19:30
Registration

Foyer
18:30—19:30
Refreshments

Foyer
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
Anne C. Ferguson-Smith, University of Cambridge, UK
Opening and Welcoming Greeting

* Steven Henikoff, Fred Hutchinson Cancer Research Center, USA

Huntington F. Willard, Duke University, USA
Epigenetics in Complex Genomes: What's the Genome Do?

20:30—21:30
Orientation for New Attendees and New Investigators
Keystone Symposia's Chief Scientific Officer, Dr. Andy Robertson, to lead discussion in a "What to Expect during your Attendance" for interested delegates.

Colorado Ballroom

TUESDAY, JANUARY 6

07:00—08:00
Breakfast

Summit Gallery
08:00—11:15
Chromatin Dynamics
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
* Barbara J. Meyer, University of California, Berkeley, USA

Bradley R. Cairns, HHMI/University of Utah, USA
DNA Methylation Dynamics in Zebrafish Embryos

Steven Henikoff, Fred Hutchinson Cancer Research Center, USA
Histone Variants and Chromatin Dynamics

Jessica K. Tyler, Weill Cornell Medicine, USA
Novel Roles for Core Histone Acetylation on H3 lysine 56 in Longevity and Tumorigenesis

Geneviève Almouzni, Centre National de la Recherche Scientifique, France
During Cell Cycle - Challenges of DNA Replication and Repair

Petra Hajkova, MRC Clinical Sciences Centre, UK
Short Talk: Mechanistic Aspects of DNA Demethylation in Mouse Development

Craig S. Pikaard, HHMI/Indiana University, USA
Short Talk: Plant RNA Polymerases IV and V: Subunit Structures and Modes of Action in RNA-Directed DNA Methylation

09:20—09:40
Coffee Break

Foyer
11:15
On Own for Lunch

11:15—13:00
Poster Setup

Breckenridge Ballroom
13:00—22:00
Poster Viewing

Breckenridge Ballroom
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Functional Organization of the Nucleus
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
* Amanda G. Fisher, MRC Clinical Sciences Centre, Imperial College London, UK

Jeannie T. Lee, Massachusetts General Hospital, USA
Imprinted X Chromosome Inactivation

Gary Karpen, Lawrence Berkeley National Laboratory, University of California, Berkeley, USA
DNA Repair in Heterochromatin

Peter Fraser, Florida State University, USA
The Role of the Air Non-Coding RNA in Gene Silencing

Jane A. Skok, New York University School of Medicine, USA
Short Talk: Recombinase-Dependent Homologous Pairing of Ig Alleles: A Novel Regulatory Aspect of Allelic Exclusion

19:00—20:00
Social Hour with Lite Bites

Breckenridge Ballroom
19:30—22:00
Poster Session 1

Breckenridge Ballroom

WEDNESDAY, JANUARY 7

07:00—08:00
Breakfast

Summit Gallery
08:00—11:15
Long-Range Epigenetic Control during Development
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
* Geneviève Almouzni, Centre National de la Recherche Scientifique, France

William G. Kelly, Emory University, USA
Chromatin Remodeling and Erasure during C. elegans Germline Specification

Vincenzo Pirrotta, Rutgers University, USA
Alternative Chromatin States of Polycomb Target Genes

Barbara J. Meyer, University of California, Berkeley, USA
Targeting X-Chromosome Repression

Asifa Akhtar, Max Planck Institute of Immunobiology and Epigenetics, Germany
Dosage Compensation

Sam Schoenmakers, Erasmus MC - University Medical Center, Netherlands
Short Talk: Meiotic Sex Chromosome Inactivation in the Female Germline

Patrick J. E. C. Wijchers, Hubrecht Institute, Netherlands
Short Talk: Sexual Dimorphisms in Mammals

09:20—09:40
Coffee Break

Foyer
11:15
On Own for Lunch

11:15—13:00
Poster Setup

Breckenridge Ballroom
13:00—22:00
Poster Viewing

Breckenridge Ballroom
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Integrated Epigenetic Mechanisms
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
* William G. Kelly, Emory University, USA

Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Copying and Reprogramming of Heterochromatin with RNAi

Jonathan I. Gent, University of Georgia, USA
Short Talk: A Small RNA Mediated, Paternal Contribution to C. elegans Embryogenesis?

Steven E. Jacobsen, University of California, Los Angeles, USA
DNA Methylation in Arabidopsis

Timothy H. Bestor, Columbia University College of Physicians and Surgeons, USA
Interactions between DNA Methylation and Histone Modifications in Mammals

19:00—20:00
Social Hour with Lite Bites

Breckenridge Ballroom
19:30—22:00
Poster Session 2

Breckenridge Ballroom

THURSDAY, JANUARY 8

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Parental Origin-Specific Epigenetic Processes
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
* Timothy H. Bestor, Columbia University College of Physicians and Surgeons, USA

James Turner, National Institute of Medical Research, UK
Meiotic Silencing in Mammals

Sundeep Kalantry, University of Michigan Medical School, USA
Short Talk: Evolution of Xist-Requirement in the Initiation of Mouse Imprinted X-Chromosome Inactivation

Robert L. Fischer, University of California, Berkeley, USA
Imprinting in Plants

Wolf Reik, Babraham Institute, UK
Epigenetic Regulation of Imprinting, Reprogramming, and Lineage Commitment in Mammalian Development

Urszula Brykczynska, Friedrich Miescher Institute, Switzerland
Short talk: Transmission of Methylated Histones with Modifications Specific Genomic Localization by Human Spermatozoa

Nico Ruf, Babraham Institute, UK
Short Talk: Transcription is Required for Establishment of Germline Methylation Marks at Imprinted Genes

09:20—09:40
Coffee Break

Foyer
11:00
On Own for Lunch

11:00—13:00
Poster Setup

Breckenridge Ballroom
13:00—22:00
Poster Viewing

Breckenridge Ballroom
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Environmental Modulation of Epigenetic States
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
* Michael Meaney, McGill University, Canada

Paul D. Soloway, Cornell University, USA
Antagonism Between DNA and H3K27 Methylation at the Imprinted Rasgrf1 Locus

E. Jean Finnegan, CSIRO Plant Industry, Australia
Epigenetic Determinants of an Environmental Response

Jay C. Dunlap, Dartmouth Medical School, USA
Short Talk: DNA Methylation, the frq Antisense Transcript qrf, and the ATP-Dependent Chromatin-Remodeling Enzyme CHD2: Roles in the Epigenetic Transfer of Circadian Time

Frédéric L. Chedin, University of California, Davis, USA
Short talk: The DNMT3L Protein Interacts with Multiple Nucleosomal Components to Guide de novo Methylation

19:00—20:00
Social Hour with Lite Bites

Breckenridge Ballroom
19:30—22:00
Poster Session 3

Breckenridge Ballroom

FRIDAY, JANUARY 9

07:00—08:00
Breakfast

Summit Gallery
08:00—11:15
Vertebrate Developmental Epigenetics
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
* Wolf Reik, Babraham Institute, UK

Amanda G. Fisher, MRC Clinical Sciences Centre, Imperial College London, UK
Epigenetic Regulators of Pluripotency

Matthias Merkenschlager, Imperial College London, UK
Cohesins in Gene Regulation and Genome Organisation

Gerald R. Crabtree, Stanford University, USA
Understanding the Words of Chromatin Remodeling

Michael Meaney, McGill University, Canada
Epigenetic Programming of Behavior and Physiology

Simon C. Biddie, University of Bristol, UK
Short Talk: Cell-Specific Interactions of the Glucocorticoid Receptor with Chromatin

Qiaoning Guan, University of California, Berkeley, USA
Short Talk: Nutritional Epigenomics in Yeasts and Human

09:20—09:40
Coffee Break

Foyer
11:15
On Own for Lunch

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Epigenetic Mechanisms of Disease
Meeting has ended...abstracts no longer viewable online.

Colorado Ballroom
* E. Jean Finnegan, CSIRO Plant Industry, Australia

Arthur L. Beaudet, Baylor College of Medicine, USA
The Role of Epigenetics in Neurobehavioral Disorders

Kristian Helin, University of Copenhagen, Denmark
Histone Methylation at the Center of Cellular Differentiation and Disease

Andrew G. Clark, Cornell University, USA
Short Talk: Transcriptome-Wide Identification of Novel Imprinted Genes in Neonatal Mouse Brain

Andrew Chess, Massachusetts General Hospital, USA
Genome-Wide Allele-Specific Epigenomic Analyses

19:00—20:00
Social Hour with Lite Bites

Breckenridge Ballroom
20:00—23:00
Entertainment

Breckenridge Ballroom

SATURDAY, JANUARY 10

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13ES016960-01




We gratefully acknowledge additional support for this conference from:

CellCentric Ltd. Integrated DNA Technologies

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

BioMed Central Cell Press
Royal Society of Chemistry
 

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676