Beaver Run Resort Floorplan

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This meeting took place in 2009



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Omics Meets Cell Biology (B2)


Organizer(s) Ruedi H. Aebersold and Tony Pawson
January 25—30, 2009
Beaver Run Resort • Breckenridge, Colorado USA
Abstract Deadline: Sep 25, 2008
Late Abstract Deadline: Oct 28, 2008
Scholarship Deadline: Sep 25, 2008
Early Registration Deadline: Nov 25, 2008

Sponsored by Bristol-Myers Squibb Company and Novartis Institutes for BioMedical Research

Summary of Meeting:
Apart from deciphering the genomic sequences of hundreds of species, the (human) genome project has catalyzed a wave of technological innovation that is unprecedented in the life sciences. Among its most important products are a number of assays or technologies for the quantitative, global and high throughput analysis of the genome, the molecules derived from the genome and their interactions. These technologies are colloquially described as “OMICS” technologies. The data sets generated by OMICS technologies represent a unique resource for biologists. They have also raised a number of challenging technical and conceptual issues, the solutions to which will ultimately determine the impact of OMICS technologies on biology. These include the error models, completeness and reproducibility of large scale data sets, the question whether and how different data types obtained from the same systems can be integrated and, most importantly, whether validated new biological knowledge has been or will be created either from OMICS data alone or by strategies that combine OMICS and traditional approaches. This conference will bring together the leading experts representing OMICS technologies and leading cell biologists to discuss these issues.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, JANUARY 25

15:00—19:30
Registration

Foyer
18:30—19:30
Refreshments

Foyer
19:30—21:30
Keynote Session
Meeting has ended...abstracts no longer viewable online.

Peak 5
* Tony Pawson, Samuel Lunenfeld Research Institute, Canada

Marc W. Kirschner, Harvard Medical School, USA
Robustness in Biology

David B. Searls, GlaxoSmithKline Pharmaceuticals, USA
Omic Empiricism


MONDAY, JANUARY 26

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Omics and Signaling I
Meeting has ended...abstracts no longer viewable online.

Peak 5
Tony Pawson, Samuel Lunenfeld Research Institute, Canada
Signaling Networks: Bidirectional Cellular Communication

* Rudolf H. Aebersold, Institute of Molecular Systems Biology, ETH Zürich, Switzerland
Kinase-Substrate Networks

Ernst Hafen, Institute of Molecular Systems Biology, ETH Zurich, Switzerland
Control of Cell Growth

Benjamin Cosgrove, Stanford University, USA
Multi-Variate Analysis of Signaling Networks Governing Cell Phenotypic Behaviour: Applications to Hepatocyte Toxicity and Pathology

09:20—09:40
Coffee Break

Foyer
11:00
On Own for Lunch

11:00—13:00
Poster Setup

Peaks 1-4
13:00—22:00
Poster Viewing

Peaks 1-4
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Omics and Signaling II
Meeting has ended...abstracts no longer viewable online.

Peak 5
Jennifer Mummery Widmer, Institute of Molecular Biotechnology, Austrian Academy of Sciences, Austria
Short Talk: Genome-Wide Analysis of Notch Signaling during Drosophila External Sensory Organ Development by Transgenic RNAi

Sarah Teichmann, Wellcome Trust Sanger Institute, UK
Evolution of Protein Complexes and Protein Interaction Networks

* Edward A. Dennis, University of California, San Diego, USA
Lipid Metabolomics and Cell Signaling

19:00—20:00
Social Hour with Lite Bites

Peaks 1-4
19:30—22:00
Poster Session 1

Peaks 1-4

TUESDAY, JANUARY 27

07:00—08:00
Breakfast

Summit Gallery
07:00—08:00
Poster Setup

Peaks 1-4
08:00—11:00
Omics and Sub-Cellular Organization I
Meeting has ended...abstracts no longer viewable online.

Peak 5
Laurence Pelletier, Samuel Lunenfeld Research Institute, Canada
Mechanisms of Mitotic Spindle Assembly

Lucas Pelkmans, University of Zürich, Switzerland
Population Context Predicts Activity in Human Cells

* Julie Ahringer, University of Cambridge, UK
Expanding the Cell Polarity Network

Mathias Uhlén, Royal Institute of Technology, Sweden
Protein Atlas and Cell Morphology

Christopher J. Bakal, Institute of Cancer Research, UK
Short Talk: A Systems Genetics Analysis of Rho Signaling

09:20—09:40
Coffee Break

Foyer
11:00—12:00
Lunch

Peaks 1-4
12:00—14:30
Poster Session 2

Peaks 1-4
14:30—16:30
Workshop: Available Bioinformatics Resources for Cell Biologists

Peak 5
Scott R. Floyd, Duke University, USA
Using Advanced Image Analysis Methods in High-Throughput Image-Based Screens for DNA Damage

Gary Bader, University of Toronto, Canada
Biological Network Visualization and Analysis using Cytoscape and Pathway Commons

* Rolf Apweiler, European Bioinformatics Institute, UK
Databases and their Utility

Olga Vitek, Purdue University, USA
Experimental Design from a Statistics Point of View

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Omics and Sub-Cellular Organization II
Meeting has ended...abstracts no longer viewable online.

Peak 5
* Wolfgang P. Baumeister, Max Planck Institute of Biochemistry, Germany
Cryo-Electron Microscopy: From Molecules to Systems

Peer Bork, European Molecular Biology Laboratory, Germany
Databases/Data Integration/Computational Biology

Oliver Hantschel, Swiss Federal Institute of Technology Lausanne, Switzerland
Short Talk: Interaction Proteomic, Chemical Proteomic and Transcriptomic Analysis of Abl Oncoproteins and their Inhibitors

19:00
On Own for Dinner


WEDNESDAY, JANUARY 28

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Omics and Cell Metabolism I
Meeting has ended...abstracts no longer viewable online.

Peak 5
* Stephen George Oliver, Cambridge University, UK
Identifying Functional Modules using Metabolic Models

Garry P. Nolan, Stanford University, USA
Diseased Signaling Networks at the Single Cell Level

Uwe Sauer, Institute of Molecular Systems Biology, ETH Zurich, Switzerland
Unraveling Condition-Specific Networks of Active Metabolic Regulation

Trey Ideker, University of California, San Diego, USA
Mapping Gene Regulatory Pathways by Assembly of Physical and Genetic Interactions

Marta M. Lipinski, University of Maryland School of Medicine, USA
Short Talk: A Genome-Wide Image-Based Screen Identifies Global Molecular Mechanisms Regulating Mammalian Autophagy

09:20—09:40
Coffee Break

Foyer
11:00
On Own for Lunch

11:00—13:00
Poster Setup

Peaks 1-4
13:00—22:00
Poster Viewing

Peaks 1-4
16:30—17:00
Coffee Available

Foyer
17:00—19:00
Omics Experimental and Computational Strategies I
Meeting has ended...abstracts no longer viewable online.

Peak 5
David M. Sabatini, Whitehead Institute for Biomedical Research, USA
Large Scale Loss of Function Screens in Mammalian Cells

Sabine P. Cordes, Mount Sinai Hospital, Canada
The Mouse and the OMICS of Happiness

* Cheryl Arrowsmith, University of Toronto, Canada
Integrating Structural Genomics and Chemical Genomics for Biology and Medicine

Shohei Koide, New York University Langone Medical Center, USA
Short Talk: Affinity Clamps: Next-Generation Affinity Reagents

19:00—20:00
Social Hour with Lite Bites

Peaks 1-4
19:30—22:00
Poster Session 3

Peaks 1-4

THURSDAY, JANUARY 29

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Omics and DNA Damage/Cell Cycle Research
Meeting has ended...abstracts no longer viewable online.

Peak 5
Stephen J. Elledge, Harvard Medical School, USA
Integrative Approaches for DNA Damage and Cell Cycle Analysis

* Michael P. Snyder, Stanford University School of Medicine, USA
Identifying Regulators of Neuronal Differentiation by High-Throughput Screening of Embryonic Stem Cells

Daniel Durocher, Lunenfeld-Tanenbaum Research Institute, Canada
High Content-High Throughput Screens to Probe the Cellular Response to DNA Damage

Joan S. Brugge, Harvard Medical School, USA
Mining the Genome for Regulators of Cell Migration

Steven P. Gygi, Harvard Medical School, USA
Short Talk: Combining Chemical Genetics with Phosphoproteomics: Identifying Direct Cdk1 Targets in Yeast

09:20—09:40
Coffee Break

Foyer
11:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Omics Experimental and Computational Strategies II
Meeting has ended...abstracts no longer viewable online.

Peak 5
Christian von Mering, University of Zurich, Switzerland
The STRING Protein Network Resource: Data Integration for Systems Biology

Timothy R. Hughes, University of Toronto, Canada
Function and Evolution of Transcriptional Networks

* A.J. Marian Walhout, University of Massachusetts Medical School, USA
Gene-Centered Regulatory Networks

Peter V. Hornbeck, Cell Signaling Technology, USA
Short Talk: PhosphoSitePlus: A Resource Enabling both System-Wide and Reductionist Studies of Post-translational Modifications

René H. Medema, Netherlands Cancer Institute, Netherlands
Short Talk: Omics Meets Motor Proteins on the Spindle

19:00—20:00
Summary Discussion with Lite Bites

Peaks 1-4
20:00—23:00
Entertainment

Peaks 1-4

FRIDAY, JANUARY 30

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13GM085837-01




We gratefully acknowledge additional support for this conference from:

Bristol-Myers Squibb Company Cell Signaling Technology, Inc.
Lilly Singapore Centre for Drug Discovery Novartis Institutes for BioMedical Research

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Royal Society of Chemistry

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


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If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

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Phone:+1 970-262-2676