Keystone Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2009


Here are the related meetings in 2018:
T Cell Dysfunction, Cancer and Infection (A3)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Regulatory T Cells (C5)


Organizer(s) Yasmine Belkaid, Fiona M. Powrie, and Shimon Sakaguchi
March 1—6, 2009
Keystone Resort • Keystone, Colorado USA
Abstract Deadline: Nov 3, 2008
Late Abstract Deadline: Dec 2, 2008
Scholarship Deadline: Nov 3, 2008
Early Registration Deadline: Jan 5, 2009

Sponsored by Novo Nordisk A/S

Summary of Meeting:
Over the past few years Regulatory T cells have taken center stage in the field of immunoregulation. Several types of regulatory T cell have been described on the basis of their origin, generation and mechanism of action, with two main subsets identified: naturally occurring FOXP3+ regulatory T cells and inducible regulatory T cells. All types of regulatory T cell, by virtue of their capacity to control the intensity of effector responses, have been shown to play a major role in the control of immune responses at large. This meeting will highlight recent developments in our understanding of the molecular basis for the differentiation of naturally occurring or inducible regulatory T cells. The second goal is to discuss information on the targets, mechanism of action, recruitment and homeostasis of regulatory T cells. The third goal is to discuss recent advances in our understanding of the conditions favoring the emergence and regulation of these populations and to discuss how these findings are translated in clinical trials.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, MARCH 1

15:00—19:30
Registration

Longs Peak Foyer
18:30—19:30
Refreshments

Longs Peak Foyer
19:30—20:30
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
Alexander Y. Rudensky, HHMI/Memorial Sloan Kettering Cancer Center, USA
Development and Maintenance of Foxp3+Treg


MONDAY, MARCH 2

07:00—08:00
Breakfast

Quandary 1-3
08:00—11:15
Molecular Control of Foxp3+Treg
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
Dan R. Littman, HHMI/New York University School of Medicine, USA
ROR Gamma T, Foxp3, and the Th17 Lineage

Christophe Benoist, Harvard Medical School, USA
Treg Genomics

* Steven F. Ziegler, Benaroya Research Institute, University of Washington School of Medicine, USA
Regulation and Role of Foxp3 in Regulatory T Cells

Jochen Huehn, Experimental Immunology, Helmholtz Centre for Infection Research, Germany
Epigenetic Control of the Foxp3 Locus in Regulatory T Cells

Girdhari Lal, National Centre for Cell Science, India
Short Talk: Epigenetic Regulation of Foxp3 Expression in T Cells during Tolerance and Inflammation

Hozefa S. Bandukwala, Pfizer, Inc, USA
Short Talk: A Critical Role of Domain-Swapping in FOXP3 for its Induction of Suppressive Potential in T Cells

09:20—09:40
Coffee Break

Longs Peak Foyer
11:15
On Own for Lunch

11:15—13:00
Poster Setup

Quandary 1-3
13:00—22:00
Poster Viewing

Quandary 1-3
14:30—16:30
Workshop 1: Molecular Control

Grays Peak / Longs Peak
* Shimon Sakaguchi, Osaka University, Japan

Chan Wang Lio, La Jolla Institute, USA
A Two-Step Model of Thymic Regulatory T Cells Development

Lydia R. Durant, NIAMS, National Institutes of Health, USA
STAT3 Promotes Pathogenic T Cell Development in a Mouse Model of Colitis

Noriko Komatsu, RIKEN Research Center for Allergy and Immunology, Japan
Heterogeneity of Natural Foxp3+ T Cells: A Committed Regulatory T Cell Lineage and an Committed Minor Subpopulation Retaining Developmental Plasticity

Alexander Georg Scheffold, Miltenyi Biotec, Germany
Notch Switches on IL-10 Production and Suppressive Activity in Th1 Cells

Marc Beyer, German Center for Neurodegenerative Diseases, Germany
Genome-Wide mRNA and miRNA Analysis Reveals Individual miRNA-Based Regulation of the Core Transcriptome Genes in Human Regulatory T Cells

Marta Monteiro, Instituto de Medicina Molecular (VAT 506134466), Portugal
Acquisition of Foxp3 Expression and Regulatory Function by Invariant Natural Killer T Cells

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:30
Pathways of Thymic and Peripheral Treg Development
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
Ludger Klein, University of Munich, Institute for Immunology, Germany
Determinants of Intrathymic Regulatory T Cell Development

Harald von Boehmer, Harvard Medical School, USA
Prospective Tolerance by Inducing Foxp3+ Treg in Peripheral Lymphoid Tissue

* Megan K. Levings, University of British Columbia, Canada
The Role of FOXP3 in the Development and Function of Human T Regulatory Cells

Vijay K. Kuchroo, Brigham and Women's Hospital, Harvard Medical School, USA
Role of TGF-beta in Regulating the Balance between Pathogenic and Regulatory T Cells

Lin Chen, University of Southern California, USA
Short Talk: Crystal Structure of the NFAT1:FOXP3: DNA Complex Reveals New Insights into the Function of FOXP3 in Regulatory T Cells

19:30—20:30
Social Hour with Lite Bites

Quandary 1-3
19:30—22:00
Poster Session 1

Quandary 1-3

TUESDAY, MARCH 3

07:00—08:00
Breakfast

Quandary 1-3
08:00—11:15
Inducible Regulatory T Cells
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
* Anne O'Garra, Francis Crick Institute, UK
IL-10 and Immunoregulation

Catherine M. Hawrylowicz, King's College London, UK
IL-10 Secreting T Regulatory Cells in Allergy and Asthma

Dragana Jankovic, NIAID, National Institutes of Health, USA
Highly Polarized Th1 Cells as Regulatory T Cells

Wanjun Chen, NIDCR, National Institutes of Health, USA
Role of TGF-beta in Induction and Survival of Treg Cells

Monica Froicu, Yale University, USA
Short Talk: Therapeutic Effects of CD45RB Ligation on Experimental Colitis

Rachel A. Gottschalk, NIAID, National Institutes of Health, USA
Short Talk: TCR Signal Strength in the Peripheral Conversion to CD4+Foxp3+ Regulatory T Cells in vivo

09:20—09:40
Coffee Break

Longs Peak Foyer
11:15
On Own for Lunch

11:15—13:00
Poster Setup

Quandary 1-3
13:00—22:00
Poster Viewing

Quandary 1-3
14:30—16:30
Workshop 2: Mechanisms

Grays Peak / Longs Peak
* Fiona M. Powrie, University of Oxford, UK

Arthur Hurwitz, NCI, National Institutes of Health, USA
Prostatic Tumors Induce CD8+ T Cells to Become Suppressor Cells

Robert N. Barker, University of Aberdeen, UK
A New Role for Soluble CTLA-4 as a Potent Inhibitory Mediator Secreted by Antigen Stimulated CD4+ Regulatory T Cells

Derese Getnet, Johns Hopkins School of Medicine, USA
A Role for Helios in Induced Regulatory T Cells

Ashley Mahne, Merck Research Laboratories, USA
Regulatory T Cells Impede Autoimmune Diabetes by Modulating Dendritic Cell Maturation in Inflamed Islets

Ann Lauren Jagger, Stanford University, USA
CD4+CD25+Foxp3+ Regulatory T Cells Cooperate with CD4+CD25- Effector T Cells to Restore Immune Homeostasis

Carla M. Cuda, Northwestern University, USA
Pbx1 Plays a Role in Controlling the Level of Tregs in the Periphery

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
Local Control by Treg
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
Fiona M. Powrie, University of Oxford, UK
Immune Regulation in the Gut

* Juan J. Lafaille, New York University School of Medicine, USA
Control of Gut Homeostasis by Induced Treg

Rachel R. Caspi, NEI, National Institutes of Health, USA
Immune Privilege, Tregs and Autoimmunity

19:15—20:15
Social Hour with Lite Bites

Quandary 1-3
19:30—22:00
Poster Session 2

Quandary 1-3

WEDNESDAY, MARCH 4

07:00—08:00
Breakfast

Quandary 1-3
08:00—11:00
Treg in Infectious Diseases/Hygiene Hypothesis
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Plasticity of Regulatory T Cells during Infections

* Richard M. Maizels, University of Edinburgh, UK
Treg Induced by Helminths

Craig L. Maynard, University of Alabama at Birmingham, USA
Short Talk: Contrasting Roles for All-Trans Retinoic Acid in TGF-beta-Mediated Induction of Foxp3 and Il10 Genes in Developing Regulatory T Cells

Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA
Immune Regulation of HIV Infection

Eleanor M. Riley, Roslin Institute, UK
T Cell-Mediated Immunoregulation during Human and Murine Malaria Infections

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00
On Own for Lunch

11:00—13:00
Poster Setup

Quandary 1-3
13:00—22:00
Poster Viewing

Quandary 1-3
14:30—16:30
Workshop 3: Targets

Grays Peak / Longs Peak
* Yasmine Belkaid, NIAID, National Institutes of Health, USA

Linda Wammes, Erasmus Medical Center, Netherlands
Helminth Infections Induce Spill-Over Suppression by Foxp3+ Regulatory T Cells in Rural Indonesia

Eva Bjur, McGill University, Canada
Control of Anti-Tumor Immunity by CD4+FOXP3+ Regulatory T Cells in Tumor Microenvironments

Fulvia Vascotto, University Medical Center of the Johannes Gutenberg University Mainz, Germany
Role of Treg during NK Cell Mediated CHS Response

Jason A. Chesney, University of Louisville, USA
Transient Treg Depletion Causes Regression of Metastases in Stage IV Melanoma Patients

Markus Kleinewietfeld, Max Delbrueck Center for Molecular Medicine, Germany
‘Untouched’ Human Foxp3+ Treg for Clinical Therapies

Hongbo Chi, St. Jude Children's Research Hospital, USA
A Mechanism for the Reversal of Regulatory T Cell Activity to Facilitate Lymphocyte Priming

Mark Claassen, Erasmus MC - University Medical Center Rotterdam, Netherlands
Role of Multiple Human Regulatory T Cell Populations in Controlling Peripheral Blood and Liver Immunity to Hepatitis C Virus Infections

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
Targets and Mechanisms of Suppression
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
Shimon Sakaguchi, Osaka University, Japan
Construction of Treg without Foxp3: Key Roles of CTLA-4 and IL-2

* Ethan M. Shevach, NIAID, National Institutes of Health, USA
Control of Immune Responses by Natural and Adaptive Regulatory T Cells

Dario A. A. Vignali, University of Pittsburgh School of Medicine, USA
The Mechanism of Regulatory T Cell Function

Olaf Rötzschke, Singapore Immunology Network (SIgN), Singapore
Effector/Memory Treg Cells (TREM): Extracellular ATP and Immune Suppression

19:15—20:15
Social Hour with Lite Bites

Quandary 1-3
19:30—22:00
Poster Session 3

Quandary 1-3

THURSDAY, MARCH 5

07:00—08:00
Breakfast

Quandary 1-3
08:00—11:15
Treg Homeostasis and Survival
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
Talal A. Chatila, University of California, Los Angeles, USA
Dual Requirement for Natural and Induced Regulatory T Cells in Peripheral Tolerance

Daniel Campbell, Benaroya Research Institute, USA
T-bet Controls Regulatory T Cell Homeostasis and Function during Type-1 Inflammation

* Arne N. Akbar, University College London, UK
The Kinetics of CD4+Foxp3+ T Cell Accumulation during a Human Cutaneous Antigen-Specific Memory Response in vivo

Benoit L. Salomon, University Pierre et Marie Curie, France
Short Talk: Effector T Cells Limit Their Own-Pathogenicity by Activating Regulatory T Cells

Michael A. Farrar, University of Minnesota, USA
Short Talk: Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

Soyoung Oh, Memorial Sloan-Kettering Cancer Center, USA
Short Talk: Effect of TCR Specificity on the in vivo Function of CD4+CD25+ Regulatory T Cells in an Autoimmune Setting

09:20—09:40
Coffee Break

Longs Peak Foyer
11:15
On Own for Lunch

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
Treg Antigen Specificity/ Treg Homeostasis and Survival
Meeting has ended...abstracts no longer viewable online.

Grays Peak / Longs Peak
* Kingston H.G. Mills, Trinity College Dublin, Ireland
Immunotherapeutic Approaches Based on Manipulating Treg versus Th17 Cells

Maria Grazia Roncarolo, Stanford University School of Medicine, USA
Therapeutic Aspects of Naturally Occurring and Adaptive Regulatory T Cells

Matthias Edinger, University Hospital Regensburg, Germany
Treg Cells in Allogeneic Stem Cell Transplantation

Samantha Bailey-Bucktrout, Rinat, Pfizer, USA
Short Talk: T Regulatory Cell Instability Generates Pathogenic Memory T Cells in vivo

Clare M. Baecher-Allan, Brigham and Women's Hospital, Harvard Medical School, USA
Short Talk: Differential Suppression by Human Treg Subsets and the Role of Granzyme B

19:15—20:15
Social Hour with Lite Bites

Quandary 1-3
20:00—23:00
Entertainment

Quandary 1-3

FRIDAY, MARCH 6

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13AI081362-01




We gratefully acknowledge additional support for this conference from:

European Journal of Immunology JDRF
Novo Nordisk A/S
 

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Cell Press

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676