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This meeting took place in 2010


Here are the related meetings in 2018:
Vectors, Pathogens and Diseases: Current Trends and Emerging Challenges (T1)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Molecular Targets for Control of Vector-Borne Diseases: Bridging Lab and Field Research (F2)


Organizer(s) Kenneth D. Vernick, Elena A. Levashina, Gerry Killeen and Anthony A. James
April 11—16, 2010
Copper Mountain Resort • Copper Mountain, Colorado USA
Abstract Deadline: Dec 11, 2009
Late Abstract Deadline: Jan 6, 2010
Scholarship Deadline: Dec 11, 2009
Early Registration Deadline: Feb 11, 2010

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation


Summary of Meeting:
Vigorous research since the completion of the Anopheles gambiae genome sequence has established the malaria mosquito as a model organism for host-pathogen biology. However, the translation of this growing post-genomic knowledge base into new vector-targeted malaria control strategies is a distinct challenge that now leads laboratory-based molecular researchers to confront the complexity and heterogeneity of the natural malaria transmission system. Simultaneously, a body of field-based vector researchers has been developing new ways to utilize existing vector control tools such as bednets and insecticides that, if consistently implemented, can yield impressive outcomes. Lab and field based practitioners attend different meetings and rarely engage in direct dialog. This conference will examine the tension between the development of new practical malaria control tools, including genomic ones, and the advantages of more fully exploiting existing tools. It is hoped that the scientific discussion will help influence individual and programmatic research priorities.

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Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, APRIL 11

15:00—19:30
Registration

Kokopelli's
18:30—19:30
Refreshments

Kokopelli's
19:30—21:30
Keynote Address (Joint)
Meeting has ended...abstracts no longer viewable online.

Big Horn Ballroom
Michael F. Good, Griffith University, Australia
Malaria Vaccines: Lessons from Immune Escape Instruct New Strategies

Anthony A. James, University of California, Irvine, USA
Transgenic Strategies for Pathogen Transmission Control


MONDAY, APRIL 12

07:00—08:00
Breakfast

Kokopelli's/Ptarmigan B-C
08:00—11:00
Vector Populations
Meeting has ended...abstracts no longer viewable online.

Big Horn C
* Gerry F. Killeen, Liverpool School of Tropical Medicine, UK

Didier Fontenille, Institut de Recherche pour le Developpement (IRD), France
Complexity of the Malaria Vectorial System in Africa

Nora J. Besansky, University of Notre Dame, USA
Chromosome Structural Polymorphism and the Malaria Transmission System

Gregory Lanzaro, University of California, Davis, USA
The Genetic Structure of Anopheles Gambiae Populations

William C. Black IV, Colorado State University, USA
Population Genetics of Aedes aegypti and Dengue Transmission

08:00—11:15
Parasite Interactions with the Immune System
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Kate A. Fitzgerald, University of Massachusetts Medical School, USA

Paolo Arese, University of Torino Medical School, Italy
Effects of Hemozoin and Hemozoin-Generated Molecules on Immune and Non-Immune Host Cells

James Brewer, University of Glasgow, UK
Imaging Infection and Immune Responses in vivo

Jean Langhorne, Francis Crick Institute, UK
Kinetics of the Immune Response in Mice: Relevance for Human Malaria?

Takafumi Tsuboi, Ehime University, Japan
Sexual Stage Parasites and Transmission-Blocking Antibodies

Renée M. Tsolis, University of California, Davis, USA
Short Talk: Malaria Parasite Infection Suppresses Mucosal Responses to Salmonella in the Intestine

09:20—09:40
Coffee Break

Kokopelli's
11:00—13:00
Poster Setup

Big Horn Ballroom
11:00
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Big Horn Ballroom
14:30—16:30
Workshop 1

Big Horn C
* Kenneth D. Vernick, Institut Pasteur, France

14:30—15:30
Special Topics

Debaditya Bhattacharya, Tufts Medical Center, USA
Development of a Reservoir-Targeted Vaccine against Yersinia pestis

Ramavati Pal, St. John's University, USA
Insect Glutathione S-transferase Proteome and Insecticide Resistance

Linda De Vooght, Institute of Tropical Medicine, Antwerp, Belgium
Expression of Trypanosome-Development Inhibitory Proteins into the Periplasm of Sodalis glossinidius, a Bacterial Symbiont of the Tsetse Fly

15:30—16:30
Vector Biology Funding Priorities and Perspectives

* Adriana Costero-Saint Denis, NIAID, National Institutes of Health, USA
Vector Biology Funding Opportunities at the National Institute of Allergy and Infectious Diseases

Inmaculada Peñas Jiménez, European Commission, CORDIS, Belgium
European Union Funded Research on Vector Biology

16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Olfaction, Host Seeking and Behavior
Meeting has ended...abstracts no longer viewable online.

Big Horn C
* Anthony A. James, University of California, Irvine, USA

Laurence J. Zwiebel, Vanderbilt University, USA
Olfactory and Thermosensory Genomics as a Basis for Disrupting Disease Transmission by Vector Mosquitoes

Flaminia Catteruccia, Harvard School of Public Health, USA
Molecular Bases of Anopheles gambiae Reproductive Biology: A Laboratory and Field Study

Willem Takken, Wageningen University, Netherlands
Olfaction and Behavioral Ecology of Disease Vectors

17:00—19:00
Recognizing Protective Immunity
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* John T. Harty, University of Iowa, USA

Robert Sauerwein, Radboud University, Netherlands
Complete Immunity after Limited Exposure to P. falciparum in a Controlled Setting

Eleanor M. Riley, Roslin Institute, UK
Cross-Talk between Innate and Adaptive Immune Cells: Relevance for Assessing Effector Cell Responses to Malaria Vaccines

Laurent Rénia, Singapore Immunology Network, (SIgN), A*STAR, Singapore
Mechanisms of Acquired Immunity against Malaria Liver Stage Immunity

Nathan W. Schmidt, University of Louisville, USA
Short Talk: Plasmodium Species and Host Background Genes Profoundly Influence the Threshold of Memory CD8 T Cells Required for Protective Immunity

19:00—20:00
Social Hour with Lite Bites

Kokopelli's
19:30—22:00
Poster Session 1

Big Horn Ballroom

TUESDAY, APRIL 13

07:00—08:00
Breakfast

Kokopelli's/Ptarmigan B-C
08:00—11:00
Insecticides and Resistance
Meeting has ended...abstracts no longer viewable online.

Big Horn C
* Elena A. Levashina, Max Planck Institute for Infection Biology, Germany

Hilary Ranson, Liverpool School of Tropical Medicine, UK
The Molecular Genetics of Insecticide Resistance in Mosquitoes

Maureen Coetzee, University of Witwatersrand, South Africa
Insecticides and Malaria Epidemiology

Janet Hemingway, Liverpool School of Tropical Medicine, UK
Biochemistry of Insecticide Resistance

Brian D. Foy, Colorado State University, USA
The Effects of Anthelmintics on Anthropophilic Mosquitoes in the Lab and Field

08:00—11:15
Local Milieu for Host-Parasite Interactions
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Gareth Turner, Oxford University, UK

Ute Frevert, New York University School of Medicine, USA
Imaging the Immunobiology of Plasmodium in the Liver

Fidel P. Zavala, Johns Hopkins Bloomberg School of Public Health, USA
Development of Memory CD8+ T Cells Against Malaria Liver Stages

Nick Crispe, University of Washington, USA
Immune Responses in the Liver

Pierre Buffet, Pitie-Salpetriere Hospital, France
Erythrocytes Squeezing across Splenic Slits and the Pathogenesis of Plasmodium falciparum Infection

Sandra March, Massachusetts Institute of Technology, USA
Short Talk: Establishment of the Liver Stages of Plasmodium falciparum in a Microscale Human Liver Platform

Anne-Marie Zeeman, Biomedical Primate Research Centre, Netherlands
Short Talk: An Efficient in vitro Culture System to Study Malaria Dormant Liver Stages

09:20—09:40
Coffee Break

Kokopelli's
11:00—13:00
Poster Setup

Big Horn Ballroom
11:00
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Big Horn Ballroom
16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Pathogen Receptors and Cellular Interactions
Meeting has ended...abstracts no longer viewable online.

Big Horn C
* Kenneth D. Vernick, Institut Pasteur, France

Robert E. Sinden, Imperial College London, UK
The Cell Biology of Plasmodium in the Mosquito

Kenneth E. Olson, Colorado State University, USA
Interactions between Arboviruses and the Mosquito’s RNAi Pathway

Serap Aksoy, Yale University School of Public Health, USA
Microbiome Influences on Host Vector Competence

17:00—19:00
Parasite Invasion and Arrest
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Robert Sauerwein, Radboud University, Netherlands

Maria M. Mota, Instituto de Medicina Molecular, Portugal
Blood Stage /Plasmodium/ Parasites Suppress Co-Infection in the Liver

Urszula Krzych, Walter Reed Army Institute of Research, USA
Memory CD8+ T Cells in Experimental Models of Protective Immunity Induced by Attenuated Plasmodia Sporozoites

Richard J. Pleass, University of Nottingham, UK
Engineering Antibodies for Novel Malaria Vaccines

Audrey Gego, INSERM UMR S 945, France
Short Talk: Identification of New Hepatocyte Factors Involved in Malaria Liver Stage Infection by Large Scale RNAi Screening

19:00—20:00
Social Hour with Lite Bites

Kokopelli's
19:30—22:00
Poster Session 2

Big Horn Ballroom

WEDNESDAY, APRIL 14

07:00—08:00
Breakfast

Kokopelli's/Ptarmigan B-C
08:00—11:00
Host-Parasite Evolution
Meeting has ended...abstracts no longer viewable online.

Big Horn C
* Gerry F. Killeen, Liverpool School of Tropical Medicine, UK

Louis Lambrechts, Institut Pasteur, France
Genetic Specificity of Interactions between Dengue Viruses and Mosquito Vectors

Andrew Read, Pennsylvania State University, USA
Evolution-Proofing Existing Malaria Control Tools

Brian P. Lazzaro, Cornell University, USA
Evolution of Anopheles Immune Defense Genes

Marc A.T. Muskavitch, Biogen, USA
Short Talk: Implementation of a High-Density SNP Genotyping Array for the Vector Mosquito Anopheles gambiae for Analysis of Population Structure and Genetic Mapping

08:00—11:15
Malarial Disease: Contribution of Host Response
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Maria M. Mota, Instituto de Medicina Molecular, Portugal

Gareth Turner, Oxford University, UK
The Pathology of Human Malaria

Kate A. Fitzgerald, University of Massachusetts Medical School, USA
The Innate Immune Response to Malaria

Patrick E. Duffy, NIAID, National Institutes for Health, USA
Malarial Disease and the Placenta

Nick M. Anstey, Menzies School of Health Research, Australia
Disease Caused by Plasmodium vivax

Andrew E. Armitage, Weatherall Institute of Molecular Medicine, UK
Short Talk: Plasmodium falciparum Infected Erythrocytes Induce Hepcidin (HAMP) mRNA Synthesis by Peripheral Blood Mononuclear Cells

Ana Paula Freitas do Rosario, National Institute for Medical Research, UK
Short Talk: TH1 CD4+ T Cells are the Main Source of Protective IL-10 Against Immune-Mediated Pathology during Plasmodium chabaudi AS Infection

09:20—09:40
Coffee Break

Kokopelli's
11:00—13:00
Poster Setup

Big Horn Ballroom
11:00
On Own for Lunch and Recreation

13:00—22:00
Poster Viewing

Big Horn Ballroom
14:30—16:30
Workshop 2: Special Topics

Big Horn C
* Elena A. Levashina, Max Planck Institute for Infection Biology, Germany

Luciano A. Moreira, Instituto de Pesquisas René Rachou-Fiocruz, Brazil
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya and Plasmodium

Kostas Iatrou, National Centre for Scientific Research, Greece
Volatile Constituents of Plant Origin Bind Selectively Various Odorant Binding Proteins of the Malaria Vector Anopheles gambiae and Act as Strong Repellents Capable of Interfering with the Vector’s Host Seeking and Blood Feeding Activities

Igor V. Sharakhov, Virginia Polytechnic Institute, USA
Genome Landscape and Evolutionary Plasticity of Chromosomes in Malaria Mosquitoes

Judith Lum Ndamukong, University of Buea, Cameroon
Biting Densities and Transmission Potential of Malaria Vectors in the Mount Cameroon Region at Contrasting Altitudinal Zones

Hirotaka Kanuka, Jikei University School of Medicine, Japan
Midgut Bacteria Regulates Plasmodium Development in Malaria Vector Anopheles Mosquitoes

14:30—16:30
Workshop

Big Horn B
* Patrick E. Duffy, NIAID, National Institutes for Health, USA

Angela A. Aggrey, University of Rochester Medical Center, USA
The Role of Platelets in Experimental Cerebral Malaria

Noah S. Butler, University of Oklahoma Health Sciences Center, USA
Key Immune-Effector Molecules Differentially Regulate Memory CD8 T Cell-Mediated Immunity Against Liver Stage P. berghei versus P. yoelii Infection

Aubrey Cunnington, London School of Hygiene and Tropical Medicine, UK
Impairment of Host Defence during Malaria: A Possible Consequence of Heme Oxygenase-1 Induction

Lei Shong Lau, University of Melbourne, Australia
The Generation of a Blood-stage Plasmodium berghei-specific CD8+ T Cell Receptor Transgenic Mouse Model

Jenni C. Lawton, National Institute for Medical Research, UK
The cir Multi-Gene Family of Plasmodium chabaudi

Demba Sarr, University of Georgia, USA
Differential Pregnancy Outcomes of Plasmodium chabaudi AS-Infected A/J and C57BL/6 Mice

16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Insect Immunity
Meeting has ended...abstracts no longer viewable online.

Big Horn C
* Anthony A. James, University of California, Irvine, USA

Elena A. Levashina, Max Planck Institute for Infection Biology, Germany
Complement-Like System in Immune Responses of Anopheles gambiae

Alexander S. Raikhel, University of California Riverside, USA
Mosquito Immune Signaling Pathways

Kenneth D. Vernick, Institut Pasteur, France
Mapping and Functional Dissection of Mosquito Resistance to Plasmodium

17:00—19:00
Systems Biology of the Immune Response
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Dyann F. Wirth, Harvard School of Public Health, USA

Bali Pulendran, Emory University, USA
Predicting Protective Immune Responses to Vaccines

Peter D. Crompton, National Institutes of Health, USA
Using Protein Microarrays to Probe the Human Antibody Response to Plasmodium falciparum

Johanna Daily, Albert Einstein College of Medicine, USA
Parasite Transcriptional Respones to Physiologic Conditions

Erica M. Pasini, Biomedical Primate Research Centre, Netherlands
Short Talk: Identification of a Small Exported Protein Strongly Associated with Sequestration through Proteomics of the Membranes of P. berghei Infected Erythrocytes (iRBCs)

19:00—20:00
Social Hour with Lite Bites

Kokopelli's
19:30—22:00
Poster Session 3

Big Horn Ballroom

THURSDAY, APRIL 15

07:00—08:00
Breakfast

Kokopelli's/Ptarmigan B-C
08:00—11:00
Control Strategies - Current and Future I
Meeting has ended...abstracts no longer viewable online.

Big Horn C
* Kenneth D. Vernick, Institut Pasteur, France

Andrea Crisanti, Imperial College London, UK
Homing Endonuclease Transgenes in the Main Human Malaria Vector Anopheles Gambiae: From Dominant Sterility to Genetic Drive

Gerry F. Killeen, Liverpool School of Tropical Medicine, UK
Ecology: A Prerequisite for Malaria Elimination and Eradication

Catherine Bourgouin, Institut Pasteur, France
Vector Targeted Immunological Control of Malaria Transmission

Christian Lengeler, Swiss Tropical and Public Health Institute, Switzerland
From Technology Development and Field Validation to Large-Scale Vector Control Interventions

08:00—11:15
Multigene Families: Role in Immunity and Pathology
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Jean Langhorne, Francis Crick Institute, UK

Dyann F. Wirth, Harvard School of Public Health, USA
Genetic Diversity in Plasmodia

Joseph D. Smith, Seattle Biomedical Research Institute, USA
Structure-Function of DBL Domains and Vaccine Design

Peter R. Preiser, Nanyang Technological University, Singapore
Understanding the Biological Role of Small Variant Antigens in Plasmodium

Lars Hviid, University of Copenhagen, Denmark
The Naturally Acquired Human Antibody Response to Plasmodium falciparum Variant Surface Antigens

Benoit Gamain, Pasteur Institute, France
Short Talk: Full-Length Extracellular Region of the var2CSA Variant of PfEMP1 is Required for Specific, High-Affinity Binding to CSA

Marissa G. Vignali, Seattle Biomedical Research Institute, USA
Short Talk: Differential Gene Expression in P. falciparum Field Samples of Variable Disease Severity

09:20—09:40
Coffee Break

Kokopelli's
11:00
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Kokopelli's
17:00—19:00
Control Strategies - Current and Future II
Meeting has ended...abstracts no longer viewable online.

Big Horn C
* Kenneth D. Vernick, Institut Pasteur, France

Gregor J. Devine, Ifakara Health Institute, Tanzania
Adult Mosquitoes as Insecticide Delivery Agents

Luke S. Alphey, Oxitec Ltd, UK
Sterile Insects for Vector Control

17:00—19:00
Inducing Optimal Protective Responses with Vaccines
Meeting has ended...abstracts no longer viewable online.

Big Horn B
* Michael F. Good, Griffith University, Australia

John T. Harty, University of Iowa, USA
Quantifying CD8 T Cell Mediated Anti-Plasmodium Immunity and Protective Immunity after Attenuated Parasite Immunization

Joanna Kubler Kielb, National Institutes of Health, USA
A Bicomponent Pre-Erythrocytic Investigational Malaria Vaccine

Philip Bejon, University of Oxford, UK
Immunity Induced by a Partially Protective Vaccine

Julie Healer, Walter and Eliza Hall Institute of Medical Research, Australia
Short Talk: Preclinical Development of a Combined Vaccine Against Bloodstage P. falciparum Malaria

19:00—20:00
Social Hour with Lite Bites

Jack's
20:00—23:00
Entertainment

Jack's

FRIDAY, APRIL 16

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13AI088817-01




We gratefully acknowledge additional support for this conference from:

Bill & Melinda Gates Foundation

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