Registered Attendees

Registered Attendees

Print This Page

Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Close Window
Santa Fe Community Convention Center Floorplan

Santa Fe Community Convention Center Floorplan

Print This Page



Close Window

This meeting took place in 2014



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Transcriptional Regulation (Q2)


Organizer(s) Richard A. Young, Robert G. Roeder and Joanna Wysocka
February 4—9, 2014
Santa Fe Community Convention Center • Santa Fe, New Mexico USA
Discounted Abstract Deadline: Oct 15, 2013
Abstract Deadline: Nov 7, 2013
Scholarship Deadline: Oct 15, 2013
Discounted Registration Deadline: Dec 4, 2013

Supported by the Directors' Fund

Joint Meeting: Cancer Epigenetics (Q1)

Summary of Meeting:
Transcriptional regulation allows for exquisitely precise, context-dependent interpretation of genomic information and is central for the emergence of diverse cellular behaviors during development and disease. The Keystone Symposia meeting on Transcriptional Regulation will focus both on new insights into fundamentals of gene expression control and on the discussion of how these advances impact our understanding of various biological processes, including cellular plasticity and differentiation, reprogramming and cancer. Together with the concurrent symposium on Cancer Epigenetics, this meeting also aims to cover recent progress toward development of therapeutics targeting transcriptional and chromatin regulators.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, FEBRUARY 4

16:00—20:00
Arrival and Registration


WEDNESDAY, FEBRUARY 5

07:00—08:00
Breakfast

08:00—09:00
Keynote Address (Joint)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Sharon Y.R. Dent, University of Texas MD Anderson Cancer Center, USA

James E. Bradner, Dana-Farber Cancer Institute, USA
Chemical Modulation of Chromatin Structure and Function

09:00—11:45
Fundamentals at the Structural, Biochemical and Genomic Levels (Joint)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Sharon Y.R. Dent, University of Texas MD Anderson Cancer Center, USA

Craig B. Thompson, Memorial Sloan-Kettering Cancer Center, USA
Cellular Metabolism and Epigenetic Changes in Cancer

Joan W. Conaway, Stowers Institute for Medical Research, USA
Function and Regulation of the Human INO80 Complex

Patrick Cramer, Max Planck Institute for Biophysical Chemistry, Germany
Transcriptome Surveillance by Selective Termination of Non-Coding RNA Synthesis

Bing Ren, University of California, San Diego, USA
Long-Range Control Sequences in Health and Diseases

09:40—10:00
Coffee Break

11:45—13:00
Poster Setup

13:00—22:00
Poster Viewing

11:45—17:00
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

17:00—19:15
Transcription Factors and Cofactors
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Richard A. Young, Whitehead Institute for Biomedical Research, USA

Robert G. Roeder, Rockefeller University, USA
Transcriptional Coactivators: Recruitment Mechanisms and Functions

Martha L. Bulyk, Brigham & Women's Hospital and Harvard Medical School, USA
The Genomic Landscape of NF-kB Binding in Lymphoblastoid B-Cells

Eva Nogales, University of California, Berkeley, USA
Structure of the Human Transcription Preinitiation Complex

David H. Price, University of Iowa, USA
Functional Domains of Gdown1 and Regulation by Phosphorylation


Following Session is for Cancer Epigenetics (Q1)

17:00—19:15
Genomic Profiles of Chromatin Modifiers in Cancer
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Peter A. Jones, Van Andel Institute, USA

Kornelia Polyak, Dana-Farber Cancer Institute, Harvard Medical School, USA
The Functional Relevance of JARID1B in Breast Cancer

Peggy J. Farnham, University of Southern California, USA
Using Epigenetic Drugs and Genome Engineering to Target Cancer-Associated Enhancers

Dirk Schübeler, Friedrich Miescher Institute for Biomedical Research, Switzerland
Genomic Patterns and Context Specific Interpretation of DNA Methylation

Dan A. Landau, Dana-Farber Cancer Institute and the Broad Institute, USA
Short Talk: Locally Disordered DNA Methylation Forms the Basis of Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution

James J. Morrow, Case Western Reserve University School of Medicine, USA
Short Talk: Specific Alterations in the Enhancer Epigenome Drive a Unique Transcriptional Program to Mediate the Metastatic Phenotype in Osteosarcoma

19:15—20:15
Social Hour with Lite Bites

19:30—22:00
Poster Session 1


THURSDAY, FEBRUARY 6

07:00—08:00
Breakfast

07:30—08:00
Poster Setup

08:00—19:00
Poster Viewing

08:00—11:00
Transcriptional Control in Development
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Robert G. Roeder, Rockefeller University, USA

Michael S. Levine, University of California, Berkeley, USA
Pause Control in Development

Karen Adelman, NIEHS, National Institutes of Health, USA
RNA Polymerase II Pausing in Pluripotent Stem Cells

Joanna Wysocka, Stanford University School of Medicine, USA
Mechanisms of Developmental Plasticity

Margaret T. Fuller, Stanford University, USA
Cell Type Specific Transcriptional Repression Programs Proper Differentiation a Stem Cell Lineage

Artem Barski, Cincinnati Children's Hospital, USA
Short Talk: Rapid Recall Ability of Memory T Cells Is Encoded in their Epigenome


Following Session is for Cancer Epigenetics (Q1)

08:00—11:00
Histone Modifiers in Development and Cancer
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Mark T. Bedford, University of Texas MD Anderson Cancer Center, USA

Robert A. Waterland, Baylor College of Medicine, USA
Early Nutritional Influences on Human Metastable Epialleles

Sharon Y.R. Dent, University of Texas MD Anderson Cancer Center, USA
A SAGA of GCN5 and USP22 in Development and Disease

Yi Zhang, HHMI/Harvard Medical School, Children's Hospital Boston, USA
Mechanism and Function of Tet-Mediated 5mC Oxidation

Sung Hee Baek, Seoul National University, South Korea
Histone Modifiers in Epigenetic Control of Stem Cell Homeostasis and Cancer

Andy J. Andrews, Fox Chase Cancer Center, USA
Short Talk: Herding KATs: How Acetyl-CoA and Small Molecules Can Alter Selectivity of CBP and p300

09:20—09:40
Coffee Break

11:00—12:00
Lunch

12:00—14:30
Poster Session 2

14:30—15:00
Coffee Available

15:00—17:00
ncRNAs
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Karen Adelman, NIEHS, National Institutes of Health, USA

Howard Y. Chang, Stanford University, USA
Genome Regulation by Long Noncoding RNAs

John L. Rinn, Harvard University, USA
Linking RNA to Nuclear Architecture

Christopher K. Glass, University of California, San Diego, USA
Enhancer RNAs: Noise, Consequence or Contributors to Enhancer Function?

Michael Jordan Rowley, University of Michigan, USA
Short Talk: Gene Expression and Heterochromatin Edge Control via Transcriptional Gene Silencing


Following Session is for Cancer Epigenetics (Q1)

15:00—17:00
Genetic and Epigenetic Interactions in Cancer
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Margaret A. Goodell, Baylor College of Medicine, USA

Susan J. Clark, Garvan Institute of Medical Research, Australia
CpG Island Methylation in Cancer: What Is the Trigger?

Megan P. Hitchins, Stanford University School of Medicine, USA
Epimutations and Epialleles in Familial Cancer

Xiaobing Shi, University of Texas MD Anderson Cancer Center, USA
Short Talk: Histone Variant H3.3-Specific Readout of H3K36 Trimethylation by ZMYND11

Ki Eun Pyo, Seoul National University, South Korea
Short Talk: EZH2 Generates a Methyl Degron that Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex

17:00—
On Own for Dinner


FRIDAY, FEBRUARY 7

07:00—08:00
Breakfast

08:00—11:00
Transcription, Development and Disease
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Joanna Wysocka, Stanford University School of Medicine, USA

Leonard I. Zon, HHMI/Children's Hospital Boston, USA
Transcription Elongation in Blood Development and Cancer

Joaquín M. Espinosa, University of Colorado, Boulder, USA
Mechanisms of Transcriptional Regulation in the p53 Network

Kenneth S. Zaret, University of Pennsylvania, USA
Regulatory Mechanisms in Mammalian Tissue Induction and Cell Reprogramming

Thomas G. Boyer, University of Texas Health Science Center at San Antonio, USA
Uterine Leiomyoma-Linked MED12 Mutations Disrupt Mediator-Associated CDK Activity

Michael L. Stitzel, The Jackson Laboratory for Genomic Medicine, USA
Short Talk: Stretch Enhancers, Cell Identity and GWAS


Following Session is for Cancer Epigenetics (Q1)

08:00—11:00
Aging, Epigenetic Variation and Cancer
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Robert A. Waterland, Baylor College of Medicine, USA

Jean-Pierre Issa, Temple University School of Medicine, USA
Epigenetic Drift in Aging and Cancer

Margaret A. Goodell, Baylor College of Medicine, USA
DNA Methylation in Normal and Malignant Hematopoiesis

Taiping Chen, University of Texas MD Anderson Cancer Center, USA
Crosstalk between DNA Methylation and Histone Methylation in Mammalian Development and Disease

Johnathan R. Whetstine, Massachusetts General Hospital, USA
Chromatin Modulators Provide a New Insight into Cancer Genomes

Brian C. Capell, University of Pennsylvania, USA
Short Talk: Senescence Leads to Epigenomic Disruption Invoking Hallmarks of Reprogramming and Pluripotency

09:20—09:40
Coffee Break

11:00—13:00
Poster Setup

13:00—22:00
Poster Viewing

11:00—14:30
On Own for Lunch and Recreation

14:30—16:30
Workshop: Transcriptional Regulation

* Michael S. Levine, University of California, Berkeley, USA

Benjamin R. Sabari, Rockefeller University, USA
Metabolic Regulation of Transcription through Differential Histone Acylations

Elizabeth M. Duncan, Stowers Institute for Medical Research, USA
Set1 Regulates Genes Required for Stem Cell Function in Schmidtea mediterranea

Alessandro Gardini, Wistar Institute, USA
Integrator Regulates Transcriptional Pausing and Elongation at Immediate Early Genes

Matthias Merkenschlager, Imperial College London, UK
Features of Cohesin-Mediated Gene Regulation

Jian Yan, Karolinska Institutet, Sweden
Inheritance of the Transcriptional Regulatory Landscape in Human Cells

Andrew Xiao, Yale University, USA
A Novel Epigenetic Pathway Regulating ES Heterogeneity

Lorenzo Pasquali, Institut d'Investigacions Biomèdiques August Pi i Sunyer
Pancreatic Islet Epigenomics Reveals Enhancer Clusters that Are Enriched in Type 2 Diabetes

Kai Ge, NIDDK, National Institutes of Health, USA
Enhancer Regulation by H3K4me1/2 Methyltransferase MLL4


Following Session is for Cancer Epigenetics (Q1)

14:30—16:30
Workshop: Current Topics in Epigenetics

* Johnathan R. Whetstine, Massachusetts General Hospital, USA

Calley L. Hirsch, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Canada
Characterizing the Earliest Epigenetic Events in Reprogramming

Alessia Cavazza, Dana Farber Cancer Institute, Harvard Medical School, USA
CNOT3 Regulates an Embryonic Stem Cell-Like Self-Renewal Pathway in Colorectal Cancer

Collene R. Jeter, University of Texas MD Anderson Medical Center, USA
NANOG Regulation of Prostate Tumorigenesis

Gregory David, New York University School of Medicine, USA
An Epigenetic Program Required for Oncogene-Induced Senescence Drives Inflammation and Pancreatic Cancer Progression

Wa Zhang, University of Nebraska Medical Center, USA
The Molecular Pathology of DNA Hypomethylation in Epithelial Ovarian Cancer (EOC)

Daniel Thomas, Stanford University, USA
Wilms' Tumor 1 Mutation is a Driver of DNA Hyper-Methylation in Acute Myeloid Leukemia

16:30—17:00
Coffee Available

17:00—19:00
Therapeutics Discovery (Joint)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Jean-Pierre Issa, Temple University School of Medicine, USA

Mark T. Bedford, University of Texas MD Anderson Cancer Center, USA
Defining New Histone Reader Domains

Peter A. Jones, Van Andel Institute, USA
Targeting Chromatin for Therapy

Yali Dou, University of Michigan, USA
Targeting H3 K4 Methylation by MLL1 in Treatment of Mixed Lineage Leukemia

Rui Li, University of Texas Southwestern Medical Center, USA
Short Talk: Suppression of Estrogen-Induced Gene Expression in Breast Cancer Cells by the BET Inhibitor JQ1

19:00—20:00
Social Hour with Lite Bites

19:30—22:00
Poster Session 3


SATURDAY, FEBRUARY 8

07:00—08:00
Breakfast

08:00—11:00
Programming and Reprogramming (Joint)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Kenneth S. Zaret, University of Pennsylvania, USA

Amanda G. Fisher, MRC Clinical Sciences Centre, Imperial College London, UK
Human X Chromosome Reactivation by Cell Fusion Reprogramming

Chris J.C. van Oevelen, Centre for Genomic Regulation, Spain
C/EBPa Orchestrates the Activity of Distinct Enhancer Types during Transdifferentiation

Jacob Hanna, Weizmann Institute of Science, Israel
Molecular Mechanisms for Inducing and Maintaining Pluripotent States

Richard A. Young, Whitehead Institute for Biomedical Research, USA
Roles for Transcriptional Super-Enhancers in Cell Identity and Disease

09:20—09:40
Coffee Break

11:00—17:00
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

17:00—19:00
Cellular and Global Views of Transcription
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Bing Ren, University of California, San Diego, USA

Job Dekker, University of Massachusetts Medical School, USA
Chromosome Folding and Gene Regulation

B. Franklin Pugh, Pennsylvania State University, USA
Genome-Wide Organization of Chromatin and the Transcription Machinery

Michael Snyder, Stanford University School of Medicine, USA
Analysis of Regulatory Networks within and between Species

Frédéric L. Chedin, University of California, Davis, USA
Short Talk: Transcription Protects CpG Island Promoters from DNA Methylation Independently of Histone H3 lysine 4 Trimethylation


Following Session is for Cancer Epigenetics (Q1)

17:00—19:00
Epigenetic Therapies
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Susan J. Clark, Garvan Institute of Medical Research, Australia

Stephen B. Baylin, Johns Hopkins University School of Medicine, USA
Role of Epigenetics in Cancer Treatments

Caretha L. Creasy, GlaxoSmithKline Pharmaceuticals, USA
Therapeutic Opportunities for EZH2 Methyltransferase Inhibitors in Lymphoma

Kenneth P. Nephew, Indiana University, USA
Epigenetic Therapies that Overcome Cancer Drug Resistance

Michael P. Kladde, University of Florida, USA
Short Talk: Epigenetic Profiling Identifies Drug-Tolerant Glioblastoma Cells

19:00—20:00
Social Hour with Lite Bites

20:00—23:00
Entertainment


SUNDAY, FEBRUARY 9

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Amanda Deem, Assistant Director of Development, Email: AmandaD@keystonesymposia.org,
Phone:+1 970-262-2668

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676