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This meeting took place in 2016
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Metabolism, Transcription and Disease (J2)
Organizer(s) Peter Verrijzer, Katherine A. Jones and Paolo Sassone-Corsi
January 10—14, 2016
Snowbird Resort • Snowbird, Utah USA
Discounted Abstract Deadline: Sep 23, 2015
Abstract Deadline: Oct 22, 2015
Scholarship Deadline: Sep 23, 2015
Discounted Registration Deadline: Nov 12, 2015
Supported by the Directors' Fund
Joint Meeting:
Nuclear Receptors: Full Throttle (J1)
Summary of Meeting:
To maintain homeostasis, cells need to coordinate gene expression and metabolic state. There is increasing evidence that misregulation of metabolic flux and gene transcription plays a major role in human diseases, including obesity, diabetes and cancer. The aim of this meeting is to explore how metabolic state influences gene expression programs and, conversely, how intermediary metabolism is controlled by the transcription machinery and chromatin-modulating enzymes. Particular emphasis will be on the connection between gene transcription and metabolism in homeostatic and diseased state. Emerging evidence emphasizes that chromatin-modifying enzymes depend on substrates, or co-factors, that are key components of intermediary metabolism. The cellular concentration of these metabolites fluctuates in response to, for example, nutrient availability, circadian cycles or oncogenic transformation. Thus, chromatin might be considered a sensor of metabolic state. Moreover, some metabolic enzymes play surprisingly direct roles in transcription control. Conversely, transcriptional control of metabolic enzyme expression, for example by nuclear receptors or the oncogene Myc, plays a major role in maintaining homeostasis, circadian rhythm or driving cell growth and proliferation. The aim of this Keystone Symposia meeting is to bring together scientists working on basic aspects of transcription control, epigenetics, metabolic disease and cancer. The meeting should serve as a discussion platform to explore the rapidly growing interphase between transcription regulation, metabolic reprogramming and human disease.
View Scholarships/Awards
To maintain homeostasis, cells need to coordinate gene expression and metabolic state. There is increasing evidence that misregulation of metabolic flux and gene transcription plays a major role in human diseases, including obesity, diabetes and cancer. The aim of this meeting is to explore how metabolic state influences gene expression programs and, conversely, how intermediary metabolism is controlled by the transcription machinery and chromatin-modulating enzymes. Particular emphasis will be on the connection between gene transcription and metabolism in homeostatic and diseased state. Emerging evidence emphasizes that chromatin-modifying enzymes depend on substrates, or co-factors, that are key components of intermediary metabolism. The cellular concentration of these metabolites fluctuates in response to, for example, nutrient availability, circadian cycles or oncogenic transformation. Thus, chromatin might be considered a sensor of metabolic state. Moreover, some metabolic enzymes play surprisingly direct roles in transcription control. Conversely, transcriptional control of metabolic enzyme expression, for example by nuclear receptors or the oncogene Myc, plays a major role in maintaining homeostasis, circadian rhythm or driving cell growth and proliferation. The aim of this Keystone Symposia meeting is to bring together scientists working on basic aspects of transcription control, epigenetics, metabolic disease and cancer. The meeting should serve as a discussion platform to explore the rapidly growing interphase between transcription regulation, metabolic reprogramming and human disease.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, January 10 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 14 with a closing plenary session and keynote address from 17:00 to 20:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 15 in order to fully experience the meeting.
SUNDAY, JANUARY 10
MONDAY, JANUARY 11
TUESDAY, JANUARY 12
WEDNESDAY, JANUARY 13
THURSDAY, JANUARY 14
FRIDAY, JANUARY 15
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, January 10 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 14 with a closing plenary session and keynote address from 17:00 to 20:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 15 in order to fully experience the meeting.
SUNDAY, JANUARY 10
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
08:00—09:00
Welcome and Keynote Address (Joint)
Meeting has ended...abstracts no longer viewable online.
*
Carol A. Lange,
University of Minnesota, USA
*
Peter Verrijzer,
Erasmus University Medical Center, Netherlands
Robert T. Tjian,
HHMI/University of California, Berkeley, USA
Probing Transcription Regulation by Single Molecule Imaging
Probing Transcription Regulation by Single Molecule Imaging
09:00—11:30
Transcription and Human Disease (Joint)
Meeting has ended...abstracts no longer viewable online.
Danny F. Reinberg,
HHMI/New York University, USA
Epigenetic Regulation by Polycomb Complexes
Epigenetic Regulation by Polycomb Complexes
Susanne Mandrup,
University of Southern Denmark, Denmark
Reorganization of the 3D Chromatin Structure during Adipocyte Differentiation
Reorganization of the 3D Chromatin Structure during Adipocyte Differentiation
Mitchell A. Lazar,
Perelman School of Medicine, University of Pennsylvania, USA
Nuclear Receptors and the Transcriptional Regulation of Circadian Rhythms and Metabolism
Nuclear Receptors and the Transcriptional Regulation of Circadian Rhythms and Metabolism
Asifa Akhtar,
Max Planck Institute of Immunobiology and Epigenetics, Germany
Epigenetic Regulation by MOF Containing Complexes
Epigenetic Regulation by MOF Containing Complexes
14:30—16:30
Workshop 1: NR Interactions with DNA and the Transcriptional Machinery
NR Interactions with DNA & the Transcriptional Machinery
*
Carolyn L. Smith,
Baylor College of Medicine, USA
Sofie Johanna Desmet,
Ghent University/VIB, Belgium
Cofactor Profiling Following Selective Modulation of the Glucocorticoid Receptor
Cofactor Profiling Following Selective Modulation of the Glucocorticoid Receptor
Jay Gertz,
University of Utah, USA
Functional Dissection of Estrogen Receptor Alpha Bound Enhancers at their Endogenous Loci
Functional Dissection of Estrogen Receptor Alpha Bound Enhancers at their Endogenous Loci
Ville Paakinaho,
National Institutes of Health, USA
Single-Molecule Analysis of Glucocorticoid Receptor and Cofactor Action in Living Cells
Single-Molecule Analysis of Glucocorticoid Receptor and Cofactor Action in Living Cells
Jing Yang,
Baylor College of Medicine, USA
The Histone Demethylase PHF8, a Novel Interacting Partner of the SMRT Coregulator, Promotes Estrogen Receptor-alpha Transcriptional Activity
The Histone Demethylase PHF8, a Novel Interacting Partner of the SMRT Coregulator, Promotes Estrogen Receptor-alpha Transcriptional Activity
Dinny Graham,
Westmead Institute for Medical Research, University of Sydney, Australia
Differential Effects of Cell Type and Nuclear Environment on Progesterone Receptor Isoform Function
Differential Effects of Cell Type and Nuclear Environment on Progesterone Receptor Isoform Function
Coralie Poulard,
University of Southern California, USA
Crosstalk between Automethylation and Phosphorylation Tightly Regulates G9a Coactivator Function with Steroid Hormone Receptors
Crosstalk between Automethylation and Phosphorylation Tightly Regulates G9a Coactivator Function with Steroid Hormone Receptors
Bart Kolendowski,
University of Western Ontario, Canada
The Role of Thymine DNA Glycosylase (TDG) in Estrogen Receptor Signalling and Enhancer RNA Regulation in Breast Cancer
The Role of Thymine DNA Glycosylase (TDG) in Estrogen Receptor Signalling and Enhancer RNA Regulation in Breast Cancer
Sean W. Fanning,
University of Chicago, USA
Bazedoxifene Potently Inhibits Y537S and D538G ESR1 Somatic Mutants by Disrupting the Constitutively Active AF-2 Conformational State
Bazedoxifene Potently Inhibits Y537S and D538G ESR1 Somatic Mutants by Disrupting the Constitutively Active AF-2 Conformational State
17:00—19:00
Epigenetics and Chromatin as a Metabolic Sensor
Meeting has ended...abstracts no longer viewable online.
*
Asifa Akhtar,
Max Planck Institute of Immunobiology and Epigenetics, Germany
Hans-Martin Herz,
St. Jude Children's Research Hospital, USA
Short Talk: The Histone H3 Lysine 4 to Methionine (H3K4M) Mutant as a Tool to Study Enhancer-Mediated Processes
Short Talk: The Histone H3 Lysine 4 to Methionine (H3K4M) Mutant as a Tool to Study Enhancer-Mediated Processes
Katrin F. Chua,
Stanford University Medical Center, USA
Chromatin Regulation and Genome Maintenance by Mammalian Sirtuins
Chromatin Regulation and Genome Maintenance by Mammalian Sirtuins
Tokameh Mahmoudi,
Erasmus Universiteit Rotterdam, Netherlands
Signaling to Chromatin and Viral Latency
Signaling to Chromatin and Viral Latency
Melanie M. Ott,
University of California, San Francisco, USA
Metabolic Reprogramming of T Cells by SIRT1
Metabolic Reprogramming of T Cells by SIRT1
17:00—19:00
Co-Regulators
Meeting has ended...abstracts no longer viewable online.
*
Karen E. Knudsen,
Thomas Jefferson University, Kimmel Cancer Center, USA
Qianben Wang,
Ohio State University, USA
Precise and Dynamic Definition of Nuclear Receptor Collaborator and Coregulator Cistromes
Precise and Dynamic Definition of Nuclear Receptor Collaborator and Coregulator Cistromes
Carol A. Lange,
University of Minnesota, USA
Stress-Responsive Gene Regulation by GR/HIF/PELP1 Complexes in Triple-Negative Breast Cancer
Stress-Responsive Gene Regulation by GR/HIF/PELP1 Complexes in Triple-Negative Breast Cancer
Timothy E. Reddy,
Duke University, USA
Short Talk: Massively Parallel Reporter Assays Reveal Glucocorticoid Receptor Interaction Modules that Direct Gene Expression Responses to Corticosteroids
Short Talk: Massively Parallel Reporter Assays Reveal Glucocorticoid Receptor Interaction Modules that Direct Gene Expression Responses to Corticosteroids
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Signaling to Chromatin and Human Disease
Meeting has ended...abstracts no longer viewable online.
Gerald R. Crabtree,
Stanford University, USA
ATP-Dependent Chromatin Remodeling: Insights from New Methods and the Genomics of Human Disease
ATP-Dependent Chromatin Remodeling: Insights from New Methods and the Genomics of Human Disease
Irina M. Bochkis,
University of Virginia, USA
Short Talk: Reorganization of Lamina-Associated Domains in Aged Liver Alters Binding of Pioneer Factor Foxa2
Short Talk: Reorganization of Lamina-Associated Domains in Aged Liver Alters Binding of Pioneer Factor Foxa2
*
Jerry L. Workman,
Stowers Institute for Medical Research, USA
Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism
Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism
W. Lee Kraus,
University of Texas Southwestern Medical Center, USA
Nuclear NAD+ Signaling through DNA-dependent PARPs and the Control of Gene Expression
Nuclear NAD+ Signaling through DNA-dependent PARPs and the Control of Gene Expression
Juan Du,
Beckman Research Institute of City of Hope, USA
Short Talk: Chromatin Variation Driven by Transposable Elements Is a Key Contributor to Liver Metabolism in Mice
Short Talk: Chromatin Variation Driven by Transposable Elements Is a Key Contributor to Liver Metabolism in Mice
Ali Shilatifard,
Northwestern University, USA
Enhancer Malfunction in Cancer
Enhancer Malfunction in Cancer
08:00—11:15
From Chromatin to Clinic
Meeting has ended...abstracts no longer viewable online.
*
Scott M. Dehm,
University of Minnesota, USA
Karen E. Knudsen,
Thomas Jefferson University, Kimmel Cancer Center, USA
Nuclear Receptor-DNA Repair Crosstalk: Bench to Bedside
Nuclear Receptor-DNA Repair Crosstalk: Bench to Bedside
John A. Katzenellenbogen,
University of Illinois at Urbana-Champaign, USA
Novel Ligands for Estrogen Receptor and Androgen Receptor Targeted Therapies
Novel Ligands for Estrogen Receptor and Androgen Receptor Targeted Therapies
Susan K. Logan,
New York University School of Medicine, USA
Transcription Repression in Prostate Cancer
Transcription Repression in Prostate Cancer
Amy Peterson,
BeiGene, USA
Advances in the Use of Selective Androgen Receptor Modulators as Cancer Therapies
Advances in the Use of Selective Androgen Receptor Modulators as Cancer Therapies
Yiru Chen Zhao,
University of Illinois at Urbana-Champaign, USA
Short Talk: Prevention of Obesity Related Breast Cancer Using Pathway Preferential Estrogens
Short Talk: Prevention of Obesity Related Breast Cancer Using Pathway Preferential Estrogens
Lisa Greene,
University of Colorado Anschutz Medical Campus, USA
Short Talk: Suppression of CD8 T-cells by Tryptophan Catabolism in Triple-Negative Breast Cancer
Short Talk: Suppression of CD8 T-cells by Tryptophan Catabolism in Triple-Negative Breast Cancer
17:00—19:00
Metabolism and Gene Control
Meeting has ended...abstracts no longer viewable online.
*
Melanie M. Ott,
University of California, San Francisco, USA
Jesper Q. Svejstrup,
Francis Crick Institute, UK
Transcription-Associated Genome Instability
Transcription-Associated Genome Instability
Frances M. Sladek,
University of California, Riverside, USA
Short Talk: Soybean Oil Induces Obesity via Linoleic Acid, Oxylipins and Nuclear Receptor HNF4alpha
Short Talk: Soybean Oil Induces Obesity via Linoleic Acid, Oxylipins and Nuclear Receptor HNF4alpha
Katherine A. Jones,
The Salk Institute, USA
Metabolic Role for CTD Kinases
Metabolic Role for CTD Kinases
Joaquín M. Espinosa,
Linda Crnic Institute for Down Syndrome, USA
Mechanisms of Transcriptional Control by HIF1 and its Cofactors in Response to Hypoxia
Mechanisms of Transcriptional Control by HIF1 and its Cofactors in Response to Hypoxia
17:00—19:00
Advances in Structures, Ligands and Energetics
Meeting has ended...abstracts no longer viewable online.
*
Myles Brown,
Dana-Farber Cancer Institute, USA
Kendall W. Nettles,
The Scripps Research Institute, USA
Predicting Phenotypic Outcomes for Estrogen Receptor Ligands
Predicting Phenotypic Outcomes for Estrogen Receptor Ligands
David L. Bain,
University of Colorado Anschutz Medical Campus, USA
Nuclear Receptor Functional Energetics and Transcriptional Regulation
Nuclear Receptor Functional Energetics and Transcriptional Regulation
Kerry Kornfeld,
Washington University Medical School, USA
Short Talk: The Nuclear Receptor HIZR-1 Mediates Zinc Homeostasis by Functioning as a Zinc Sensor and Transcription Response Effector
Short Talk: The Nuclear Receptor HIZR-1 Mediates Zinc Homeostasis by Functioning as a Zinc Sensor and Transcription Response Effector
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:00
Metabolism and Tumor Suppression
Meeting has ended...abstracts no longer viewable online.
*
Jane Mellor,
University of Oxford, UK
Jennifer Jones McCann,
Thomas Jefferson University, USA
Short Talk: Novel Action of p53 Gain-of-Function Mutations in Prostate Cancer Progression
Short Talk: Novel Action of p53 Gain-of-Function Mutations in Prostate Cancer Progression
Amanda G. Fisher,
Imperial College London, UK
Non-Invasive Imaging of Epigenetic Changes in the Developing Embryo
Non-Invasive Imaging of Epigenetic Changes in the Developing Embryo
Adrian P. Bracken,
Trinity College Dublin, Ireland
The PRC2 Complex in Cellular Proliferation and Cancer
The PRC2 Complex in Cellular Proliferation and Cancer
Selma Masri,
University of California, Irvine, USA
Short Talk: Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis
Short Talk: Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis
Craig B. Thompson,
Memorial Sloan Kettering Cancer Center, USA
Metabolic Regulation of Epigenetics
Metabolic Regulation of Epigenetics
08:00—11:15
Rapid and Integrated Signaling (Extra-Nuclear) Actions of NRs
Meeting has ended...abstracts no longer viewable online.
*
Kenneth S. Korach,
NIEHS, National Institutes of Health, USA
Ellis R. Levin,
University of California, Irvine, USA
Membrane and Nuclear-Only ERalpha Mice Inform Phenotypes and Metabolic Functions Resulting from Estrogen Action
Membrane and Nuclear-Only ERalpha Mice Inform Phenotypes and Metabolic Functions Resulting from Estrogen Action
Cheryl L. Walker,
Baylor College of Medicine, USA
Environmental Estrogens Activate Nongenomic ER Signaling to Developmentally Reprogram the Epigenome
Environmental Estrogens Activate Nongenomic ER Signaling to Developmentally Reprogram the Epigenome
Stephen R. Hammes,
University of Rochester Medical Center, USA
Crosstalk between Estrogen and mTOR Signaling in Lymphangioleiomyomatosis (LAM)
Crosstalk between Estrogen and mTOR Signaling in Lymphangioleiomyomatosis (LAM)
Zeynep Madak-Erdogan,
University of Illinois at Urbana-Champaign, USA
Systems Biology of Gene and Metabolic Regulation by Estrogen Receptors and Kinases in Breast Cancer and Metabolic Disease
Systems Biology of Gene and Metabolic Regulation by Estrogen Receptors and Kinases in Breast Cancer and Metabolic Disease
Rebecca B. Riggins,
Georgetown University, USA
Short Talk: The Extra-Nuclear Life of ERRbeta2: Cytoskeletal and Mitotic Functions of an Orphan Nuclear Receptor Splice Variant
Short Talk: The Extra-Nuclear Life of ERRbeta2: Cytoskeletal and Mitotic Functions of an Orphan Nuclear Receptor Splice Variant
Andrea R. Patterson,
Ohio State University, USA
Short Talk: The Role of Stromal Estrogen Receptor in Mammary Gland Reprogramming Following in Utero BPA Exposure
Short Talk: The Role of Stromal Estrogen Receptor in Mammary Gland Reprogramming Following in Utero BPA Exposure
17:00—19:00
Circadian and Metabolic Cycles (Joint)
Meeting has ended...abstracts no longer viewable online.
*
Mitchell A. Lazar,
Perelman School of Medicine, University of Pennsylvania, USA
Ronald M. Evans,
HHMI/The Salk Institute, USA
Nuclear Receptors—Physiology's Architect: A 30 Year Perspective
Nuclear Receptors—Physiology's Architect: A 30 Year Perspective
Paolo Sassone-Corsi,
University of California, Irvine, USA
Metabolic and Epigenetic Language of the Circadian Clock
Metabolic and Epigenetic Language of the Circadian Clock
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—09:00
Keynote Address
Meeting has ended...abstracts no longer viewable online.
*
Paolo Sassone-Corsi,
University of California, Irvine, USA
Bruce M. Spiegelman,
Harvard Medical School, USA
Transcriptional Control of Brown and Beige Fat: Basic Biology and Potential Therapeutic Pathways
Transcriptional Control of Brown and Beige Fat: Basic Biology and Potential Therapeutic Pathways
09:00—11:15
Obesity, Diabetes and Misregulation of Gene Expression
Meeting has ended...abstracts no longer viewable online.
*
Paolo Sassone-Corsi,
University of California, Irvine, USA
Amandine Chaix,
The Salk Institute for Biological Studies, USA
Short Talk: Time-Restricted Feeding is a Preventative and Therapeutic Intervention Against Diverse Nutritional Challenges
Short Talk: Time-Restricted Feeding is a Preventative and Therapeutic Intervention Against Diverse Nutritional Challenges
Carl S. Thummel,
University of Utah School of Medicine, USA
Regulation of Mitochondrial Transcription and Carbohydrate Homeostasis by the HNF4 Nuclear Receptor
Regulation of Mitochondrial Transcription and Carbohydrate Homeostasis by the HNF4 Nuclear Receptor
Shingo Kajimura,
University of California, San Francisco, USA
Molecular Basis of Beige Adipocyte Maintenance and Energy Expenditure
Molecular Basis of Beige Adipocyte Maintenance and Energy Expenditure
Anders M. Näär,
Harvard Medical School, USA
Transcriptional and MicroRNA Circuits in Metabolic Disorder
Transcriptional and MicroRNA Circuits in Metabolic Disorder
08:00—11:15
Nuclear Receptors in Cancer, Gender Benders and Other Advances
Meeting has ended...abstracts no longer viewable online.
*
Jonna Frasor,
University of Illinois, Chicago, USA
Christine Louise Clarke,
Westmead Millennium Institute, Australia
Progesterone Action in Normal Breast and Breast Cancer
Progesterone Action in Normal Breast and Breast Cancer
Gail S. Prins,
University of Illinois, USA
Estrogenic Regulation of Prostate Stem and Progenitor Cells: Differential Actions through ERalpha and ERbeta
Estrogenic Regulation of Prostate Stem and Progenitor Cells: Differential Actions through ERalpha and ERbeta
Jennifer K. Richer,
University of Colorado Anschutz Medical Campus, USA
Subtype-Specific AR Action in Breast Cancer
Subtype-Specific AR Action in Breast Cancer
John A. Cidlowski,
NIEHS, National Institutes of Health, USA
Stress Hormone Signaling and Heart Disease: The Good, the Bad, and the Deadly
Stress Hormone Signaling and Heart Disease: The Good, the Bad, and the Deadly
Diana M. Cittelly,
University of Colorado Anschutz Medical Campus, USA
Short Talk: Ovarian and Brain Estrogens Promote Brain Metastases of Triple-Negative Breast Cancer
Short Talk: Ovarian and Brain Estrogens Promote Brain Metastases of Triple-Negative Breast Cancer
Christopher M. McNair,
Thomas Jefferson University, USA
Short Talk: RB Loss Re-Programs E2F1 and AR Cistromes in Prostate Cancer
Short Talk: RB Loss Re-Programs E2F1 and AR Cistromes in Prostate Cancer
14:30—16:30
Workshop 2: Signal Transduction and NR Actions
*
Carol A. Lange,
University of Minnesota, USA
Christy Hagan,
University of Kansas Medical Center, USA
Progesterone Receptor Promotes Inflammatory Gene Programs in Breast Cancer
Progesterone Receptor Promotes Inflammatory Gene Programs in Breast Cancer
Lynsey M. Fettig,
University of Colorado, USA
Progesterone Receptor-Retinoic Acid Receptor Crosstalk in Regulating a Breast Cancer Stem Cell Population
Progesterone Receptor-Retinoic Acid Receptor Crosstalk in Regulating a Breast Cancer Stem Cell Population
Michael A. Gordon,
University of Colorado Anschutz Medical Campus, USA
Targeting Multiple Pathways in Breast Cancer: Androgen Receptor, HER2, and mTOR
Targeting Multiple Pathways in Breast Cancer: Androgen Receptor, HER2, and mTOR
Daniel E. Frigo,
University of Houston, USA
Regulation of AMPK by Androgen Receptor Signaling and its Role in Prostate Cancer Metabolism
Regulation of AMPK by Androgen Receptor Signaling and its Role in Prostate Cancer Metabolism
Zhenqi Zhou,
University of California, Los Angeles, USA
ERalpha Deficiency-Induced Mitochondrial Dysfunction and Skeletal Muscle Insulin Resistance is Mediated by Imbalanced Fission-Fusion Dynamics in Females
ERalpha Deficiency-Induced Mitochondrial Dysfunction and Skeletal Muscle Insulin Resistance is Mediated by Imbalanced Fission-Fusion Dynamics in Females
Hari Singhal,
University of Chicago, USA
Progesterone Receptor Agonists, Antagonists and Isoforms Differentially Reprogram Estrogen Signaling in Breast Cancer
Progesterone Receptor Agonists, Antagonists and Isoforms Differentially Reprogram Estrogen Signaling in Breast Cancer
17:00—19:00
Transcriptional Control of Cell Growth
Meeting has ended...abstracts no longer viewable online.
*
Katherine A. Jones,
The Salk Institute, USA
James T. Kadonaga,
University of California, San Diego, USA
Operating Systems, Apps, and Novel Chromatin Structures for the Regulation of Our Genes
Operating Systems, Apps, and Novel Chromatin Structures for the Regulation of Our Genes
Claudio Villanueva,
University of Utah School of Medicine, USA
Short Talk: TLE3 is a Gatekeeper of the Beige Transcriptional Program
Short Talk: TLE3 is a Gatekeeper of the Beige Transcriptional Program
Don Ayer,
University of Utah, USA
c-Myc and MondoA Couple Nutrient Utilization and Availability in Tumorigenesis
c-Myc and MondoA Couple Nutrient Utilization and Availability in Tumorigenesis
Peter Verrijzer,
Erasmus University Medical Center, Netherlands
Transcription Control by Nucleotide Biosynthetic Enzymes
Transcription Control by Nucleotide Biosynthetic Enzymes
17:00—18:00
NRs as Modulators of Immune Cell Function
Meeting has ended...abstracts no longer viewable online.
*
Jennifer K. Richer,
University of Colorado Anschutz Medical Campus, USA
Inez Rogatsky,
Weill Medical College of Cornell University, USA
Transcriptional Cofactor NCoA2/GRIP1 in Macrophage Polarization and Metabolic Control
Transcriptional Cofactor NCoA2/GRIP1 in Macrophage Polarization and Metabolic Control
Christopher K. Glass,
University of California, San Diego, USA
Influence of Tissue Environment on Macrophage Identity and Function
Influence of Tissue Environment on Macrophage Identity and Function
18:00—18:45
Closing Keynote Address
Meeting has ended...abstracts no longer viewable online.
Joe Thornton,
University of Chicago, USA
Nuclear Receptor Evolution: How NR Structures and Functions Came to Be
Nuclear Receptor Evolution: How NR Structures and Functions Came to Be
20:00—21:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
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Symposia, please contact: Sarah Lavicka,
Director of Development, Email: sarahl@keystonesymposia.org, Phone:+1 970-262-2690 Click here for more information on Industry Support and Recognition Opportunities. If you are interested in becoming an advertising/marketing in-kind partner, please contact: Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org, Phone:+1 970-262-2676 |